𝕏

Task 54921132

Name HuVeMOp_20240627034041599520_ORdGradInc_k_24-Pueyo_APDR-conf_971_0
Workunit 26078825
Created 27 Jun 2024, 1:40:49 UTC
Sent 27 Jun 2024, 3:40:59 UTC
Report deadline 30 Jun 2024, 13:16:59 UTC
Received 27 Jun 2024, 16:32:22 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 237767
Run time 1 hours 28 min 16 sec
CPU time 1 hours 27 min 1 sec
Validate state Valid
Credit 63.22
Device peak FLOPS 4.40 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.50 MB
Peak swap size 3.82 MB
Peak disk usage 0.26 MB

Stderr output

<core_client_version>7.20.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627034041599520_ORdGradInc_k_24-Pueyo_APDR-conf_971.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627034041599520_ORdGradInc_k_24-Pueyo_APDR-conf_971_0_r1036434274_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627034041599520_ORdGradInc_k_24-Pueyo_APDR-conf_971_0_r1036434274_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 102.213908
     * GNaL_b in INaL: 0.008359
     * Gto_b in Ito: 0.091802
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032695
     * GKs_b in IKs: 0.001882
     * GK1_b in IK1: 0.177426
     * Gncx_b in INaCa_i: 0.000960
     * Pnak_b in INaK: 64.041670
     * GKb_b in IKb: 0.003987
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.034466
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12101277, states[0] = -16.776965, states[40]= 0.001226
Saving checkpoint... 
Iteration: 24261796, states[0] = -95.084019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35952561, states[0] = -95.169959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48093404, states[0] = -9.118812, states[40]= 0.002494
Saving checkpoint... 
Iteration: 59921159, states[0] = -95.156113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 72111337, states[0] = -24.515274, states[40]= 0.000797
Saving checkpoint... 
Iteration: 84342422, states[0] = -95.125298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 96477083, states[0] = -95.161912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 108548139, states[0] = 13.761935, states[40]= 0.004821
Saving checkpoint... 
Iteration: 120554807, states[0] = 11.358031, states[40]= 0.004798
Saving checkpoint... 
Iteration: 132652509, states[0] = -68.207756, states[40]= 0.000002
Saving checkpoint... 
Iteration: 144281551, states[0] = -95.081346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 156521495, states[0] = 21.336884, states[40]= 0.007794
Saving checkpoint... 
Iteration: 168659243, states[0] = -79.517569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 180771716, states[0] = -95.071573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 192834782, states[0] = -95.118137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 204903133, states[0] = -95.144749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 216764915, states[0] = -95.064363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 228723773, states[0] = -95.009521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 240924760, states[0] = -95.150097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 252690652, states[0] = -94.947238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 264331965, states[0] = -95.116438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 276450097, states[0] = -95.155179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 288609285, states[0] = -22.388895, states[40]= 0.000886
Saving checkpoint... 
Iteration: 300711272, states[0] = -94.988002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 312466635, states[0] = -95.157898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 324680995, states[0] = -94.901433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 336946850, states[0] = -95.154530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 348977103, states[0] = -95.159404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 361034093, states[0] = 18.377765, states[40]= 0.005236
Saving checkpoint... 
Iteration: 372675265, states[0] = -94.721426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 384311606, states[0] = -95.104011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396368749, states[0] = -95.133233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 408017464, states[0] = 21.902391, states[40]= 0.011680
Saving checkpoint... 
Iteration: 419617063, states[0] = -29.323257, states[40]= 0.000565
Saving checkpoint... 
Iteration: 431330339, states[0] = -95.115396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 442963003, states[0] = -95.157224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 454947088, states[0] = -95.154481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 467017816, states[0] = 21.861932, states[40]= 0.011152
Saving checkpoint... 
Iteration: 479074213, states[0] = 3.266489, states[40]= 0.004533
Saving checkpoint... 
Iteration: 491171809, states[0] = -94.273815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 503127811, states[0] = -39.319389, states[40]= 0.000165
Saving checkpoint... 
Iteration: 515047340, states[0] = 14.074422, states[40]= 0.004827
Saving checkpoint... 
Iteration: 527110598, states[0] = -23.553443, states[40]= 0.000838
Saving checkpoint... 
Iteration: 539200653, states[0] = -94.967847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 551248267, states[0] = -95.044547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 562902237, states[0] = -95.144123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 575006024, states[0] = 25.284655, states[40]= 0.135327
Saving checkpoint... 
Iteration: 586670277, states[0] = -93.845848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 598285957, states[0] = -95.084305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 610360412, states[0] = -95.129740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 622704546, states[0] = -94.975284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 634980499, states[0] = -95.159651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 647080447, states[0] = 0.046672, states[40]= 0.004208
Saving checkpoint... 
Iteration: 659270444, states[0] = -95.069717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 671456865, states[0] = -95.156042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 683800503, states[0] = -95.095937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 696118543, states[0] = -30.659127, states[40]= 0.000495
Saving checkpoint... 
Iteration: 707668514, states[0] = -93.026547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 719681046, states[0] = -94.901691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 731615222, states[0] = -27.670931, states[40]= 0.000650
Saving checkpoint... 
Iteration: 743669087, states[0] = -93.340712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 755639362, states[0] = -51.577547, states[40]= 0.000026
Saving checkpoint... 
Iteration: 767674414, states[0] = -94.652957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 779720874, states[0] = -95.004285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 791320794, states[0] = -95.109564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 803336232, states[0] = -95.118290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 814977793, states[0] = -95.159142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 826638858, states[0] = -51.004146, states[40]= 0.000028
Saving checkpoint... 
Iteration: 838635117, states[0] = -46.848148, states[40]= 0.000054
Saving checkpoint... 
Iteration: 850633587, states[0] = -45.204431, states[40]= 0.000070
Saving checkpoint... 
Iteration: 862131639, states[0] = -43.163381, states[40]= 0.000094
Saving checkpoint... 
Iteration: 874151588, states[0] = -66.777692, states[40]= 0.000002
Saving checkpoint... 
Iteration: 886148143, states[0] = -62.133456, states[40]= 0.000004
Saving checkpoint... 
Iteration: 898301712, states[0] = -95.096669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 909947724, states[0] = -95.154250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 922019105, states[0] = 21.700196, states[40]= 0.009598
Saving checkpoint... 
Iteration: 934096033, states[0] = -10.753218, states[40]= 0.002157
Saving checkpoint... 
Iteration: 946141061, states[0] = -53.532177, states[40]= 0.000019
Saving checkpoint... 
Iteration: 958392433, states[0] = -95.140944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 970368219, states[0] = -95.132589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 981990355, states[0] = -95.160659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 994060044, states[0] = 9.386017, states[40]= 0.004782
Saving checkpoint... 
Iteration: 1005625167, states[0] = -36.775573, states[40]= 0.000235
Saving checkpoint... 
Iteration: 1017598272, states[0] = -12.655022, states[40]= 0.001811
Saving checkpoint... 
Iteration: 1029594558, states[0] = -9.536775, states[40]= 0.002401
Saving checkpoint... 
Iteration: 1041134600, states[0] = -46.288700, states[40]= 0.000059
Saving checkpoint... 
Iteration: 1053087724, states[0] = -4.418547, states[40]= 0.003474
Saving checkpoint... 
Iteration: 1065060536, states[0] = 9.192715, states[40]= 0.004779
Saving checkpoint... 
Iteration: 1076595365, states[0] = -10.198202, states[40]= 0.002267
Saving checkpoint... 
Iteration: 1088695720, states[0] = -94.957565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1100701563, states[0] = -94.969186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1112778952, states[0] = -95.077629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1124753389, states[0] = -95.050459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1136812108, states[0] = -95.103767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1148823083, states[0] = -95.110670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1160853238, states[0] = -95.126235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1172868457, states[0] = -95.132525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1184841786, states[0] = -95.120831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1196894500, states[0] = -95.141390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1208880598, states[0] = -95.136910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1220875514, states[0] = -95.135115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232501361, states[0] = 47.973796, states[40]= 0.060795
Saving checkpoint... 
Iteration: 1244100155, states[0] = -14.292411, states[40]= 0.001556
Saving checkpoint... 
Iteration: 1256064613, states[0] = 7.546275, states[40]= 0.004746
Saving checkpoint... 
Iteration: 1268093960, states[0] = -9.053339, states[40]= 0.002502
Saving checkpoint... 
Iteration: 1279287966, states[0] = -95.085502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1291292783, states[0] = -95.089477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1302957100, states[0] = -95.155599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1314984126, states[0] = -95.159613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1327014307, states[0] = 22.207322, states[40]= 0.019684
Saving checkpoint... 
Iteration: 1339082302, states[0] = -1.006928, states[40]= 0.004064
Saving checkpoint... 
Iteration: 1351249022, states[0] = -95.044889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1363317732, states[0] = -95.107229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1375435063, states[0] = -95.151425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1387494826, states[0] = -95.160889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1399534791, states[0] = 18.173182, states[40]= 0.005192
Saving checkpoint... 
Iteration: 1411573015, states[0] = 3.839101, states[40]= 0.004574
Saving checkpoint... 
Iteration: 1423608568, states[0] = -21.751418, states[40]= 0.000914
Saving checkpoint... 
Iteration: 1435247698, states[0] = -95.043140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1446834933, states[0] = -95.117111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1458873020, states[0] = -95.134024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1470874410, states[0] = -95.134524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1482924492, states[0] = -95.149049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1494909973, states[0] = -95.145499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1506595908, states[0] = -95.363593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1518294890, states[0] = -95.374423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1529837446, states[0] = -81.339143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1541782492, states[0] = -13.700086, states[40]= 0.001866
Saving checkpoint... 
Iteration: 1553670366, states[0] = -95.380518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1565684332, states[0] = -95.395366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1577735948, states[0] = 15.390769, states[40]= 0.006095
Saving checkpoint... 
Iteration: 1589734031, states[0] = 16.167056, states[40]= 0.006231
Saving checkpoint... 
Iteration: 1601611787, states[0] = -95.321688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1613567656, states[0] = -95.231154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1625165487, states[0] = -0.026244, states[40]= 0.004789
Saving checkpoint... 
Iteration: 1637088595, states[0] = -95.406127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1648676696, states[0] = -95.255013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1660604700, states[0] = -37.678714, states[40]= 0.000207
Saving checkpoint... 
Iteration: 1672579865, states[0] = -12.042099, states[40]= 0.002194
Saving checkpoint... 
Iteration: 1684129108, states[0] = -95.349435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1696205568, states[0] = 27.249351, states[40]= 0.135955
Saving checkpoint... 
Iteration: 1708206890, states[0] = 25.284568, states[40]= 0.106862
Saving checkpoint... 
Iteration: 1719707407, states[0] = -40.675899, states[40]= 0.000138
Saving checkpoint... 
Iteration: 1731652287, states[0] = 7.579018, states[40]= 0.005490
Saving checkpoint... 
Iteration: 1743635046, states[0] = 15.682497, states[40]= 0.006153
Saving checkpoint... 
Iteration: 1755702883, states[0] = -35.757697, states[40]= 0.000266
Saving checkpoint... 
Iteration: 1767617898, states[0] = 21.515275, states[40]= 0.012407
Saving checkpoint... 
Iteration: 1779171676, states[0] = -95.243305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1791136446, states[0] = -83.086078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1802673177, states[0] = -94.874058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1814561682, states[0] = 7.739574, states[40]= 0.004809
Saving checkpoint... 
Iteration: 1826094985, states[0] = -11.632739, states[40]= 0.002016
Saving checkpoint... 
Iteration: 1837158142, states[0] = -80.900541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1849114033, states[0] = -27.618593, states[40]= 0.000651
Saving checkpoint... 
Iteration: 1861216438, states[0] = -95.006813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1873238246, states[0] = -95.037751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1884856993, states[0] = -95.132667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1896416730, states[0] = -95.150692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1908335730, states[0] = -95.119850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1920303601, states[0] = -95.099138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1932332277, states[0] = -95.116606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1944323486, states[0] = -95.111193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1956366977, states[0] = -95.131958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1968353980, states[0] = -95.126350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1980344665, states[0] = -95.121896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1991911640, states[0] = -95.145716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2003503027, states[0] = 35.729471, states[40]= 0.159055
Saving checkpoint... 
Iteration: 2015064876, states[0] = 7.434135, states[40]= 0.004743
Saving checkpoint... 
Iteration: 2027050038, states[0] = 13.118302, states[40]= 0.004810
Saving checkpoint... 
Iteration: 2038858724, states[0] = -95.127922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2050434070, states[0] = -95.150668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2061917148, states[0] = -95.146827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2073576761, states[0] = 2.003089, states[40]= 0.004425
Saving checkpoint... 
Iteration: 2085519098, states[0] = 21.701209, states[40]= 0.009606
Saving checkpoint... 
Iteration: 2097124099, states[0] = -35.768845, states[40]= 0.000269
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -95.036747
 - CaMKt in component CaMK (millimolar): 0.007530
 - cass in component intracellular_ions (millimolar): 0.000075
 - nai in component intracellular_ions (millimolar): 6.787247
 - nass in component intracellular_ions (millimolar): 6.787311
 - ki in component intracellular_ions (millimolar): 145.182381
 - kss in component intracellular_ions (millimolar): 145.182360
 - cansr in component intracellular_ions (millimolar): 1.342410
 - cajsr in component intracellular_ions (millimolar): 1.303228
 - cai in component intracellular_ions (millimolar): 0.000076
 - m in component INa (dimensionless): 0.003570
 - hf in component INa (dimensionless): 0.882322
 - hs in component INa (dimensionless): 0.882317
 - j in component INa (dimensionless): 0.882290
 - hsp in component INa (dimensionless): 0.730220
 - jp in component INa (dimensionless): 0.882271
 - mL in component INaL (dimensionless): 0.000048
 - hL in component INaL (dimensionless): 0.712209
 - hLp in component INaL (dimensionless): 0.452380
 - a in component Ito (dimensionless): 0.000618
 - iF in component Ito (dimensionless): 0.999873
 - iS in component Ito (dimensionless): 0.615488
 - ap in component Ito (dimensionless): 0.000315
 - iFp in component Ito (dimensionless): 0.999873
 - iSp in component Ito (dimensionless): 0.689557
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.929735
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999866
 - jca in component ICaL (dimensionless): 0.999974
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001718
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.332868
 - xs1 in component IKs (dimensionless): 0.254297
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997301
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
11:20:15 (231744): called boinc_finish(0)

</stderr_txt>
]]>


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