𝕏

Task 54919920

Name HuVeMOp_20240627033041315565_ORdGradInc_k_24-Pueyo_APDR-conf_396_0
Workunit 26078224
Created 27 Jun 2024, 1:30:54 UTC
Sent 27 Jun 2024, 3:40:59 UTC
Report deadline 30 Jun 2024, 13:16:59 UTC
Received 27 Jun 2024, 23:58:29 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 237767
Run time 1 hours 28 min 28 sec
CPU time 1 hours 27 min 12 sec
Validate state Valid
Credit 60.64
Device peak FLOPS 4.40 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.50 MB
Peak swap size 3.82 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.20.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627033041315565_ORdGradInc_k_24-Pueyo_APDR-conf_396.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627033041315565_ORdGradInc_k_24-Pueyo_APDR-conf_396_0_r1985963648_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627033041315565_ORdGradInc_k_24-Pueyo_APDR-conf_396_0_r1985963648_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 109.367449
     * GNaL_b in INaL: 0.006830
     * Gto_b in Ito: 0.072090
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.032629
     * GKs_b in IKs: 0.001883
     * GK1_b in IK1: 0.160556
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 64.833553
     * GKb_b in IKb: 0.003798
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037451
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12594247, states[0] = -16.805699, states[40]= 0.001261
Saving checkpoint... 
Iteration: 24677948, states[0] = -94.786870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 36649129, states[0] = -76.808722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48273450, states[0] = -94.927804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59881776, states[0] = -94.988760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 71817920, states[0] = -94.955436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 83767845, states[0] = -94.911983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 95690412, states[0] = -94.789482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 107592658, states[0] = -13.197972, states[40]= 0.001780
Saving checkpoint... 
Iteration: 119574440, states[0] = 0.558103, states[40]= 0.004443
Saving checkpoint... 
Iteration: 131609508, states[0] = -29.257888, states[40]= 0.000514
Saving checkpoint... 
Iteration: 143261171, states[0] = -94.900164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 154873660, states[0] = -94.975607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 166923593, states[0] = -94.990116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 178954418, states[0] = -94.996150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 190898145, states[0] = -94.983207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 202487902, states[0] = -95.000927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 214081366, states[0] = -3.742333, states[40]= 0.003734
Saving checkpoint... 
Iteration: 225983455, states[0] = -95.000251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 238063891, states[0] = 6.005500, states[40]= 0.004939
Saving checkpoint... 
Iteration: 250152983, states[0] = -80.652001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 262225295, states[0] = -94.850480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 274219294, states[0] = -94.840539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 286286730, states[0] = -94.924378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 298246253, states[0] = -94.880948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 310337886, states[0] = -94.959036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 322395204, states[0] = -94.982004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 334076647, states[0] = -0.677141, states[40]= 0.004269
Saving checkpoint... 
Iteration: 346042223, states[0] = 15.137966, states[40]= 0.005471
Saving checkpoint... 
Iteration: 358062422, states[0] = 6.685438, states[40]= 0.004978
Saving checkpoint... 
Iteration: 370057737, states[0] = 8.772051, states[40]= 0.005079
Saving checkpoint... 
Iteration: 381674558, states[0] = -94.704238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 393716397, states[0] = -94.835461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 405720772, states[0] = -94.842933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 417785664, states[0] = -94.923357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 429828235, states[0] = -94.953685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 441469624, states[0] = -94.998090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 453056868, states[0] = 9.148184, states[40]= 0.005096
Saving checkpoint... 
Iteration: 465001450, states[0] = 49.684558, states[40]= 0.054983
Saving checkpoint... 
Iteration: 476552098, states[0] = 11.164296, states[40]= 0.005185
Saving checkpoint... 
Iteration: 488625050, states[0] = -44.760868, states[40]= 0.000066
Saving checkpoint... 
Iteration: 500163265, states[0] = -93.200222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 511822228, states[0] = -94.950094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 523826698, states[0] = -94.952744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 535938870, states[0] = -94.992685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 547900056, states[0] = -94.983299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 559901084, states[0] = -94.983587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 571476153, states[0] = -94.998964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 583543445, states[0] = 14.660036, states[40]= 0.005420
Saving checkpoint... 
Iteration: 595463240, states[0] = -94.997014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 607052885, states[0] = 10.836746, states[40]= 0.005170
Saving checkpoint... 
Iteration: 619231796, states[0] = -94.860380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 630931848, states[0] = -94.991176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 642486576, states[0] = -95.000320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 654123684, states[0] = -43.308497, states[40]= 0.000082
Saving checkpoint... 
Iteration: 666165886, states[0] = -94.029876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 678223014, states[0] = -94.846496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 690258263, states[0] = -94.895513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 702365174, states[0] = -94.971305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 714431948, states[0] = -94.991149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 726469035, states[0] = -94.997837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 738055189, states[0] = 9.866689, states[40]= 0.005127
Saving checkpoint... 
Iteration: 749762821, states[0] = -94.900639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 761933087, states[0] = -94.991364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 773586075, states[0] = -7.282064, states[40]= 0.002981
Saving checkpoint... 
Iteration: 785600219, states[0] = -20.245161, states[40]= 0.000971
Saving checkpoint... 
Iteration: 796849877, states[0] = -94.964648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 808846043, states[0] = -94.962828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 820455397, states[0] = -94.995588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 832428052, states[0] = -94.990233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 844092669, states[0] = -13.057363, states[40]= 0.001803
Saving checkpoint... 
Iteration: 856155709, states[0] = -85.302732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 868231406, states[0] = -94.859646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 879890660, states[0] = -94.980277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 891960414, states[0] = -94.996387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 903933478, states[0] = -94.991365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 915934279, states[0] = -94.991526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 928045127, states[0] = 13.994996, states[40]= 0.005360
Saving checkpoint... 
Iteration: 940017361, states[0] = 23.137202, states[40]= 0.013821
Saving checkpoint... 
Iteration: 951662194, states[0] = -92.653572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 963694930, states[0] = -94.794481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 975695382, states[0] = -94.795395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 987639416, states[0] = -61.059759, states[40]= 0.000004
Saving checkpoint... 
Iteration: 999275530, states[0] = -94.913672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1010862827, states[0] = -94.970176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1022849302, states[0] = -94.964250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1034454864, states[0] = -94.995373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1046495962, states[0] = -95.001232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1058573535, states[0] = 1.126462, states[40]= 0.004512
Saving checkpoint... 
Iteration: 1070599877, states[0] = -19.916515, states[40]= 0.000994
Saving checkpoint... 
Iteration: 1082622008, states[0] = -41.554899, states[40]= 0.000106
Saving checkpoint... 
Iteration: 1094363004, states[0] = -94.970200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1106385116, states[0] = -94.978354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1118408922, states[0] = -94.985423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1130047395, states[0] = 13.087091, states[40]= 0.005292
Saving checkpoint... 
Iteration: 1142079582, states[0] = -2.527396, states[40]= 0.003963
Saving checkpoint... 
Iteration: 1154135337, states[0] = -56.248649, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1165789128, states[0] = -94.925905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1177772136, states[0] = -94.910216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1189910320, states[0] = -94.985750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1201879724, states[0] = -94.976464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1213856760, states[0] = -94.967498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1225878094, states[0] = -94.975877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1237910920, states[0] = -94.985879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1249948929, states[0] = -94.994197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1261535230, states[0] = 17.769006, states[40]= 0.005921
Saving checkpoint... 
Iteration: 1273086307, states[0] = -7.470141, states[40]= 0.002939
Saving checkpoint... 
Iteration: 1285153023, states[0] = -80.713028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1296816995, states[0] = -94.946379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1308945806, states[0] = -94.993585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1320944988, states[0] = -94.993424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1332871533, states[0] = -94.973415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1344953965, states[0] = -94.995039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1356921183, states[0] = -94.988358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1368524598, states[0] = 21.254950, states[40]= 0.007831
Saving checkpoint... 
Iteration: 1380568566, states[0] = 3.748535, states[40]= 0.004778
Saving checkpoint... 
Iteration: 1392598350, states[0] = -18.449899, states[40]= 0.001109
Saving checkpoint... 
Iteration: 1404136607, states[0] = -57.725055, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1416193984, states[0] = -94.792280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1427840697, states[0] = -94.959829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1439821978, states[0] = -94.949407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1451447083, states[0] = -94.993742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1463427999, states[0] = -94.989858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1475492411, states[0] = -95.000565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1487553653, states[0] = 10.515445, states[40]= 0.005155
Saving checkpoint... 
Iteration: 1499640117, states[0] = -61.910660, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1511612244, states[0] = -95.148690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1523656173, states[0] = -95.216835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1535261227, states[0] = -95.058608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1547284291, states[0] = -95.125423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1559263882, states[0] = -95.080860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1570793797, states[0] = -95.274084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1582792213, states[0] = -95.275605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1594352550, states[0] = -95.017406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1606318081, states[0] = -60.239641, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1618303274, states[0] = -41.831905, states[40]= 0.000105
Saving checkpoint... 
Iteration: 1630302756, states[0] = -41.264270, states[40]= 0.000114
Saving checkpoint... 
Iteration: 1641983998, states[0] = -20.443146, states[40]= 0.001031
Saving checkpoint... 
Iteration: 1654026199, states[0] = -72.159066, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1665659814, states[0] = 1.930929, states[40]= 0.005195
Saving checkpoint... 
Iteration: 1677288939, states[0] = -95.278653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1689261797, states[0] = -95.256746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1700856605, states[0] = -95.063757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1712904461, states[0] = -95.182144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1724875070, states[0] = -95.121614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1736767374, states[0] = -3.603016, states[40]= 0.004227
Saving checkpoint... 
Iteration: 1748371179, states[0] = -95.265201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1759534124, states[0] = 15.992927, states[40]= 0.006952
Saving checkpoint... 
Iteration: 1771559472, states[0] = 2.145238, states[40]= 0.005224
Saving checkpoint... 
Iteration: 1783163766, states[0] = -95.258681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1795144860, states[0] = -95.239475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1806732604, states[0] = -94.909883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1818702127, states[0] = -94.846999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1830223035, states[0] = -94.875375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1842208833, states[0] = -94.842183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1854163897, states[0] = -93.834206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1866134934, states[0] = -56.638617, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1878159222, states[0] = -90.794470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1890170617, states[0] = -94.603043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1902141204, states[0] = -63.589555, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1913634154, states[0] = -55.103142, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1925629276, states[0] = -49.522122, states[40]= 0.000031
Saving checkpoint... 
Iteration: 1937578803, states[0] = -2.067091, states[40]= 0.004046
Saving checkpoint... 
Iteration: 1949220660, states[0] = -94.842799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1961254317, states[0] = -94.890767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1972962545, states[0] = -94.996557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1985021988, states[0] = 21.977098, states[40]= 0.009017
Saving checkpoint... 
Iteration: 1996935038, states[0] = -94.991263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2008853202, states[0] = -94.965597, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2020441745, states[0] = -94.992477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2032462543, states[0] = -94.996117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2044471726, states[0] = -94.997494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2056090356, states[0] = -10.945365, states[40]= 0.002196
Saving checkpoint... 
Iteration: 2068135076, states[0] = -55.948936, states[40]= 0.000011
Saving checkpoint... 
Iteration: 2080158807, states[0] = -89.728387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2092239595, states[0] = -94.870846, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.876926
 - CaMKt in component CaMK (millimolar): 0.006885
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.744643
 - nass in component intracellular_ions (millimolar): 6.744703
 - ki in component intracellular_ions (millimolar): 145.233750
 - kss in component intracellular_ions (millimolar): 145.233731
 - cansr in component intracellular_ions (millimolar): 1.311383
 - cajsr in component intracellular_ions (millimolar): 1.273707
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003628
 - hf in component INa (dimensionless): 0.879568
 - hs in component INa (dimensionless): 0.879563
 - j in component INa (dimensionless): 0.879535
 - hsp in component INa (dimensionless): 0.725015
 - jp in component INa (dimensionless): 0.879516
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709699
 - hLp in component INaL (dimensionless): 0.452566
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.622455
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.697018
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.933322
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999881
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001612
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.341760
 - xs1 in component IKs (dimensionless): 0.241822
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997344
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
18:43:21 (232385): called boinc_finish(0)

</stderr_txt>
]]>


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