𝕏

Task 54918111

Name HuVeMOp_20240627031542242209_ORdGradInc_k_24-Pueyo_APDR-conf_463_1
Workunit 26077366
Created 27 Jun 2024, 1:15:48 UTC
Sent 27 Jun 2024, 3:02:50 UTC
Report deadline 30 Jun 2024, 12:38:50 UTC
Received 29 Jun 2024, 12:53:32 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 218836
Run time 1 hours 43 min 45 sec
CPU time 58 min 49 sec
Validate state Valid
Credit 61.94
Device peak FLOPS 5.93 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.70 MB
Peak swap size 5.31 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627031542242209_ORdGradInc_k_24-Pueyo_APDR-conf_463.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627031542242209_ORdGradInc_k_24-Pueyo_APDR-conf_463_1_r1690518805_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627031542242209_ORdGradInc_k_24-Pueyo_APDR-conf_463_1_r1690518805_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 105.327713
     * GNaL_b in INaL: 0.005710
     * Gto_b in Ito: 0.079087
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.033974
     * GKs_b in IKs: 0.001857
     * GK1_b in IK1: 0.152028
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 64.877758
     * GKb_b in IKb: 0.003978
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.051058
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11514825, states[0] = 21.628990, states[40]= 0.019815
Saving checkpoint... 
Iteration: 24881215, states[0] = -94.932934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 38309890, states[0] = -94.886359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 51822072, states[0] = -94.886443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 65438837, states[0] = -94.923174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 79023157, states[0] = 19.938168, states[40]= 0.008127
Saving checkpoint... 
Iteration: 92289340, states[0] = -94.852883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 105546176, states[0] = 11.647703, states[40]= 0.005174
Saving checkpoint... 
Iteration: 119150933, states[0] = -85.974296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 132492829, states[0] = -94.922755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 145740747, states[0] = -94.796781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 154978944, states[0] = -94.920341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 168171349, states[0] = -94.629119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 181405702, states[0] = -94.905893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 194788145, states[0] = -94.847426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 208031025, states[0] = 17.528872, states[40]= 0.006202
Saving checkpoint... 
Iteration: 221486117, states[0] = -94.920567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 234604182, states[0] = -29.594800, states[40]= 0.000452
Saving checkpoint... 
Iteration: 248139074, states[0] = -67.879162, states[40]= 0.000001
Saving checkpoint... 
Iteration: 261493935, states[0] = -94.921391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 274745840, states[0] = -94.802526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 287945102, states[0] = -94.914236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 301291602, states[0] = -94.849988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 314732823, states[0] = -94.784358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 328145981, states[0] = -77.824093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 341424559, states[0] = -94.910040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 354649881, states[0] = -84.139606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 368020794, states[0] = 20.632002, states[40]= 0.009504
Saving checkpoint... 
Iteration: 381410324, states[0] = -94.906622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 394625701, states[0] = -52.172316, states[40]= 0.000018
Saving checkpoint... 
Iteration: 407969908, states[0] = -94.918185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 421286722, states[0] = -94.845840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 434707686, states[0] = -94.742065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 448073932, states[0] = -1.957110, states[40]= 0.004027
Saving checkpoint... 
Iteration: 461418522, states[0] = -94.908583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474871438, states[0] = -94.894574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 487993730, states[0] = -94.921198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 501327239, states[0] = -94.874178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 514692244, states[0] = -94.711368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 527957376, states[0] = -94.916194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 541384045, states[0] = -94.898920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 554570363, states[0] = 0.239628, states[40]= 0.004354
Saving checkpoint... 
Iteration: 567719106, states[0] = -94.762382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 580916752, states[0] = -94.908091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 594163580, states[0] = -94.274116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 607594895, states[0] = -20.318010, states[40]= 0.000934
Saving checkpoint... 
Iteration: 620774229, states[0] = -94.834336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 633999830, states[0] = -94.921786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 647243561, states[0] = -94.799276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 660578457, states[0] = -5.137051, states[40]= 0.003424
Saving checkpoint... 
Iteration: 674014811, states[0] = 22.033369, states[40]= 0.019686
Saving checkpoint... 
Iteration: 687378225, states[0] = -94.896875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 700713835, states[0] = -94.753141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 713899598, states[0] = -94.903547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 727024864, states[0] = 19.509734, states[40]= 0.007491
Saving checkpoint... 
Iteration: 740297726, states[0] = -94.854540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 753699928, states[0] = -94.726894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 767105399, states[0] = -30.808477, states[40]= 0.000398
Saving checkpoint... 
Iteration: 780417319, states[0] = -94.908108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 793513764, states[0] = 22.271131, states[40]= 0.023770
Saving checkpoint... 
Iteration: 806666896, states[0] = -94.513607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 820133231, states[0] = -60.728253, states[40]= 0.000004
Saving checkpoint... 
Iteration: 833405716, states[0] = -94.905153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 846682543, states[0] = -94.689359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 860102673, states[0] = -28.081882, states[40]= 0.000522
Saving checkpoint... 
Iteration: 873667460, states[0] = -94.536582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 887044968, states[0] = 12.190820, states[40]= 0.005212
Saving checkpoint... 
Iteration: 900311289, states[0] = -94.864123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 913613584, states[0] = -39.099907, states[40]= 0.000136
Saving checkpoint... 
Iteration: 926998246, states[0] = -94.921441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 940253588, states[0] = -94.811802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 953529357, states[0] = 18.096807, states[40]= 0.006451
Saving checkpoint... 
Iteration: 966872694, states[0] = -94.894743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 980375548, states[0] = -94.895763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 993918736, states[0] = -94.908317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1007206145, states[0] = -94.738817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1020366537, states[0] = -94.892397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1033842889, states[0] = -94.882101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1047261244, states[0] = -94.820587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1060402277, states[0] = -94.904088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1073779528, states[0] = -94.839075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1087234070, states[0] = -94.785731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1100664990, states[0] = -94.402793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1114125477, states[0] = -51.921802, states[40]= 0.000019
Saving checkpoint... 
Iteration: 1127304851, states[0] = -94.859559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1140470439, states[0] = -94.917827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1153841357, states[0] = -94.881278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167243578, states[0] = -94.798989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1180472487, states[0] = -94.918094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1193751957, states[0] = -94.809673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1207305586, states[0] = -94.860031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1220717599, states[0] = -94.759417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1234015313, states[0] = 21.921508, states[40]= 0.018101
Saving checkpoint... 
Iteration: 1247081711, states[0] = -7.747643, states[40]= 0.002862
Saving checkpoint... 
Iteration: 1260401998, states[0] = -94.903893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1273738509, states[0] = -94.791992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1286936075, states[0] = -94.911903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1300234620, states[0] = -94.786409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1313641216, states[0] = -70.738013, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1327004718, states[0] = 29.840367, states[40]= 0.144803
Saving checkpoint... 
Iteration: 1340366358, states[0] = -94.892138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1353676544, states[0] = -94.669182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1366763737, states[0] = -94.823130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1380124836, states[0] = -51.207579, states[40]= 0.000021
Saving checkpoint... 
Iteration: 1393324796, states[0] = -94.872244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406740759, states[0] = -94.795035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1419971002, states[0] = -94.917742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1433566134, states[0] = 2.580239, states[40]= 0.004616
Saving checkpoint... 
Iteration: 1446981843, states[0] = -94.919192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1460300522, states[0] = -94.856217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1473506760, states[0] = 25.738677, states[40]= 0.107771
Saving checkpoint... 
Iteration: 1486713623, states[0] = -94.752294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1499953196, states[0] = -94.914925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1513096960, states[0] = -95.064421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1526381557, states[0] = -95.183184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1539650622, states[0] = 5.777822, states[40]= 0.005523
Saving checkpoint... 
Iteration: 1553155672, states[0] = 2.486631, states[40]= 0.005175
Saving checkpoint... 
Iteration: 1566608690, states[0] = 24.904294, states[40]= 0.069178
Saving checkpoint... 
Iteration: 1580103654, states[0] = 35.133726, states[40]= 0.116776
Saving checkpoint... 
Iteration: 1593314668, states[0] = 22.210936, states[40]= 0.021834
Saving checkpoint... 
Iteration: 1606275382, states[0] = -15.766305, states[40]= 0.001547
Saving checkpoint... 
Iteration: 1619731673, states[0] = 15.485277, states[40]= 0.007050
Saving checkpoint... 
Iteration: 1632992674, states[0] = -35.714130, states[40]= 0.000221
Saving checkpoint... 
Iteration: 1646288410, states[0] = -95.097541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1659442467, states[0] = -94.700354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1672746022, states[0] = -95.186343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1686211576, states[0] = -95.140500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1699627252, states[0] = -82.491712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1712862807, states[0] = -95.037609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1726023681, states[0] = -76.307474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1739250354, states[0] = -94.978719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1752589545, states[0] = -95.224523, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1765619062, states[0] = -69.061691, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1778924106, states[0] = -95.159442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1792402658, states[0] = -95.125581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1805732779, states[0] = -94.840956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1811306783, states[0] = -94.914153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1821027193, states[0] = 18.376355, states[40]= 0.006784
Saving checkpoint... 
Iteration: 1834480247, states[0] = -94.947896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1847955040, states[0] = -94.934764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1861456663, states[0] = -94.928617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1875407220, states[0] = -94.913820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1888905245, states[0] = -94.910406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1902457408, states[0] = -94.919432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1916184391, states[0] = -94.696042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1929998714, states[0] = -94.922706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1939399119, states[0] = -94.904054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1944842484, states[0] = -94.882529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1957901944, states[0] = -94.904249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1972487584, states[0] = -94.920095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1982437363, states[0] = -94.912108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1991866618, states[0] = -94.892118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2005320179, states[0] = -94.869296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2019025389, states[0] = 19.352535, states[40]= 0.007329
Saving checkpoint... 
Iteration: 2032333921, states[0] = -94.876992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2045912946, states[0] = -94.906311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2059483162, states[0] = -94.918992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2073180108, states[0] = -94.681881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2086686274, states[0] = -94.697486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2096205048, states[0] = -94.736042, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.796775
 - CaMKt in component CaMK (millimolar): 0.006692
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.754561
 - nass in component intracellular_ions (millimolar): 6.754620
 - ki in component intracellular_ions (millimolar): 145.225779
 - kss in component intracellular_ions (millimolar): 145.225759
 - cansr in component intracellular_ions (millimolar): 1.301206
 - cajsr in component intracellular_ions (millimolar): 1.264280
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003657
 - hf in component INa (dimensionless): 0.878166
 - hs in component INa (dimensionless): 0.878161
 - j in component INa (dimensionless): 0.878134
 - hsp in component INa (dimensionless): 0.722383
 - jp in component INa (dimensionless): 0.878116
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.708787
 - hLp in component INaL (dimensionless): 0.453825
 - a in component Ito (dimensionless): 0.000628
 - iF in component Ito (dimensionless): 0.999867
 - iS in component Ito (dimensionless): 0.628233
 - ap in component Ito (dimensionless): 0.000320
 - iFp in component Ito (dimensionless): 0.999867
 - iSp in component Ito (dimensionless): 0.704453
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.940421
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999903
 - jca in component ICaL (dimensionless): 0.999981
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001568
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.325050
 - xs1 in component IKs (dimensionless): 0.228601
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997365
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
07:53:17 (4228): called boinc_finish(0)

</stderr_txt>
]]>


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