𝕏

Task 54915161

Name HuVeMOp_20240627023557214974_ORdGradInc_k_24-Pueyo_APDR-conf_790_0
Workunit 26075906
Created 27 Jun 2024, 0:36:14 UTC
Sent 27 Jun 2024, 2:31:39 UTC
Report deadline 30 Jun 2024, 12:07:39 UTC
Received 27 Jun 2024, 14:55:19 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 238678
Run time 2 hours 51 min 8 sec
CPU time 2 hours 23 min 4 sec
Validate state Valid
Credit 60.38
Device peak FLOPS 3.99 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.16 MB
Peak swap size 6.23 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627023557214974_ORdGradInc_k_24-Pueyo_APDR-conf_790.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627023557214974_ORdGradInc_k_24-Pueyo_APDR-conf_790_0_r1462355943_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627023557214974_ORdGradInc_k_24-Pueyo_APDR-conf_790_0_r1462355943_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 113.724260
     * GNaL_b in INaL: 0.006721
     * Gto_b in Ito: 0.083998
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.034074
     * GKs_b in IKs: 0.001777
     * GK1_b in IK1: 0.149008
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 69.931393
     * GKb_b in IKb: 0.003957
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.053297
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12574240, states[0] = -2.489814, states[40]= 0.003879
Saving checkpoint... 
Iteration: 25009467, states[0] = 23.141389, states[40]= 0.060772
Saving checkpoint... 
Iteration: 37217289, states[0] = -94.835435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 50020693, states[0] = 20.688681, states[40]= 0.009583
Saving checkpoint... 
Iteration: 62298348, states[0] = -94.911493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 74558816, states[0] = 7.140564, states[40]= 0.004854
Saving checkpoint... 
Iteration: 86746453, states[0] = -94.848571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 99294277, states[0] = -94.895964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 112188208, states[0] = -94.740968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 114413932, states[0] = -94.950582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 127556075, states[0] = 8.493591, states[40]= 0.004907
Saving checkpoint... 
Iteration: 141089298, states[0] = -11.713011, states[40]= 0.002002
Saving checkpoint... 
Iteration: 154431713, states[0] = -94.952013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167422020, states[0] = -94.949477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 180565192, states[0] = 4.442550, states[40]= 0.004692
Saving checkpoint... 
Iteration: 193468236, states[0] = -94.957727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 206721233, states[0] = -94.801704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 220018218, states[0] = 21.427531, states[40]= 0.012291
Saving checkpoint... 
Iteration: 233165567, states[0] = -94.073547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 246154445, states[0] = -85.736516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 259121675, states[0] = -43.730223, states[40]= 0.000070
Saving checkpoint... 
Iteration: 272463543, states[0] = -94.956632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 284493811, states[0] = -94.960708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 297824424, states[0] = -94.910926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 310813270, states[0] = -94.903841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 323879252, states[0] = -94.936298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 338129065, states[0] = -51.895598, states[40]= 0.000019
Saving checkpoint... 
Iteration: 351735233, states[0] = -94.823725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 365416541, states[0] = -94.947261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 379387130, states[0] = -94.938920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 393179136, states[0] = -94.705866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 406898355, states[0] = -94.942363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 420692569, states[0] = -94.746356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 434507454, states[0] = 24.765176, states[40]= 0.094706
Saving checkpoint... 
Iteration: 448042622, states[0] = 13.931153, states[40]= 0.005232
Saving checkpoint... 
Iteration: 461749221, states[0] = -94.843109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 475398244, states[0] = -94.942291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 489396305, states[0] = -94.941711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 503094897, states[0] = -16.977830, states[40]= 0.001218
Saving checkpoint... 
Iteration: 516504997, states[0] = 28.884455, states[40]= 0.139813
Saving checkpoint... 
Iteration: 530344774, states[0] = -94.921823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 544035353, states[0] = 16.598972, states[40]= 0.005674
Saving checkpoint... 
Iteration: 557761299, states[0] = -94.857746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 571306205, states[0] = -94.898774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 585096700, states[0] = -18.739149, states[40]= 0.001047
Saving checkpoint... 
Iteration: 598946660, states[0] = -94.953547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 613073577, states[0] = 0.078959, states[40]= 0.004262
Saving checkpoint... 
Iteration: 625771779, states[0] = -94.869048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 639776121, states[0] = -94.873390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 653229798, states[0] = -94.815226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 667033049, states[0] = 17.388031, states[40]= 0.005900
Saving checkpoint... 
Iteration: 680957616, states[0] = -94.955412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 694557077, states[0] = 8.109801, states[40]= 0.004888
Saving checkpoint... 
Iteration: 708423613, states[0] = -94.948742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 721744030, states[0] = -94.836064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 735535962, states[0] = 16.385188, states[40]= 0.005623
Saving checkpoint... 
Iteration: 748624868, states[0] = -47.203370, states[40]= 0.000041
Saving checkpoint... 
Iteration: 762071684, states[0] = 1.142236, states[40]= 0.004392
Saving checkpoint... 
Iteration: 775870559, states[0] = -94.932855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 789834835, states[0] = -94.916559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 803468867, states[0] = -94.957107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 817100725, states[0] = -22.680772, states[40]= 0.000787
Saving checkpoint... 
Iteration: 830539700, states[0] = 15.031328, states[40]= 0.005371
Saving checkpoint... 
Iteration: 844162226, states[0] = -93.135014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 857843518, states[0] = -94.921018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 871628063, states[0] = -50.765430, states[40]= 0.000023
Saving checkpoint... 
Iteration: 884972122, states[0] = -94.957536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 898840218, states[0] = -94.919331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 912967111, states[0] = -94.956782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 926898867, states[0] = -94.942217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 940790286, states[0] = -94.886127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 954824893, states[0] = -94.910818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 968817402, states[0] = -94.906169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 982613546, states[0] = -35.321855, states[40]= 0.000233
Saving checkpoint... 
Iteration: 996483509, states[0] = -94.959022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1010840798, states[0] = -94.919564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1024635132, states[0] = -58.836176, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1038351748, states[0] = -94.924839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1052229458, states[0] = -94.814464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1065941650, states[0] = -94.952339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1079664795, states[0] = -93.921048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1093480579, states[0] = -94.958585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1106885940, states[0] = -94.938118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1120762242, states[0] = -94.858498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1134406841, states[0] = -94.944330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1148550573, states[0] = 10.809917, states[40]= 0.005006
Saving checkpoint... 
Iteration: 1162312964, states[0] = -94.903142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1176728235, states[0] = -94.812452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1190937275, states[0] = -94.951406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1204998758, states[0] = -94.960723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1219074330, states[0] = -0.359306, states[40]= 0.004203
Saving checkpoint... 
Iteration: 1232478008, states[0] = -94.958162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1245998905, states[0] = -94.960716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1259598062, states[0] = -20.072419, states[40]= 0.000944
Saving checkpoint... 
Iteration: 1273718317, states[0] = -94.795804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1287725994, states[0] = -94.808773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1301550046, states[0] = 11.022366, states[40]= 0.005016
Saving checkpoint... 
Iteration: 1315108382, states[0] = -30.194308, states[40]= 0.000430
Saving checkpoint... 
Iteration: 1328562093, states[0] = 5.898652, states[40]= 0.004782
Saving checkpoint... 
Iteration: 1342557839, states[0] = 7.782463, states[40]= 0.004874
Saving checkpoint... 
Iteration: 1356699042, states[0] = -94.759287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1370866228, states[0] = -94.930832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1384837309, states[0] = -94.917543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1398673162, states[0] = -94.634693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1412292985, states[0] = -94.888114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1426554713, states[0] = 9.109666, states[40]= 0.004930
Saving checkpoint... 
Iteration: 1440283566, states[0] = -94.879955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1454027451, states[0] = 19.148858, states[40]= 0.006777
Saving checkpoint... 
Iteration: 1467555395, states[0] = 8.823633, states[40]= 0.004918
Saving checkpoint... 
Iteration: 1481556065, states[0] = 8.540796, states[40]= 0.004907
Saving checkpoint... 
Iteration: 1495860636, states[0] = -94.928477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1509635193, states[0] = 15.079108, states[40]= 0.006576
Saving checkpoint... 
Iteration: 1522767325, states[0] = -95.213638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1536533850, states[0] = -95.192129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1550769580, states[0] = -6.721904, states[40]= 0.003407
Saving checkpoint... 
Iteration: 1564829265, states[0] = 17.143044, states[40]= 0.007431
Saving checkpoint... 
Iteration: 1578812552, states[0] = -95.181950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1592955466, states[0] = -95.240338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1606359310, states[0] = -95.065849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1620358980, states[0] = 1.221241, states[40]= 0.004962
Saving checkpoint... 
Iteration: 1633990255, states[0] = -95.146625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1647985691, states[0] = -24.872617, states[40]= 0.000695
Saving checkpoint... 
Iteration: 1661669433, states[0] = -95.257390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1675450413, states[0] = -95.239171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1689321321, states[0] = 20.123410, states[40]= 0.010483
Saving checkpoint... 
Iteration: 1703379744, states[0] = -95.266183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1717438399, states[0] = -95.225599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1731324442, states[0] = 18.982246, states[40]= 0.008778
Saving checkpoint... 
Iteration: 1744679928, states[0] = -95.125021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1758757127, states[0] = -95.058900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1772002715, states[0] = -95.171965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1785772015, states[0] = -95.105994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1799830807, states[0] = -84.139105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1813507939, states[0] = 24.086795, states[40]= 0.087022
Saving checkpoint... 
Iteration: 1827852340, states[0] = -94.961965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1841557310, states[0] = 7.589103, states[40]= 0.004884
Saving checkpoint... 
Iteration: 1854963382, states[0] = -94.972333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1868747824, states[0] = -94.851697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1882402145, states[0] = -94.949932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1896477276, states[0] = -94.962486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1910792071, states[0] = -94.890222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1925377571, states[0] = -94.936801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1939477074, states[0] = -94.958942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1953029641, states[0] = 18.480245, states[40]= 0.006359
Saving checkpoint... 
Iteration: 1967214302, states[0] = -94.788822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1981681400, states[0] = -94.716149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1995300838, states[0] = -94.894210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2008985877, states[0] = -94.958876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2022667180, states[0] = -94.301123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2036772066, states[0] = -94.868570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2050867266, states[0] = -94.930860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2064326350, states[0] = -94.911038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2078146023, states[0] = -72.607922, states[40]= 0.000001
Saving checkpoint... 
Iteration: 2092019253, states[0] = 21.215337, states[40]= 0.010992
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.836193
 - CaMKt in component CaMK (millimolar): 0.006665
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.611140
 - nass in component intracellular_ions (millimolar): 6.611199
 - ki in component intracellular_ions (millimolar): 145.371402
 - kss in component intracellular_ions (millimolar): 145.371382
 - cansr in component intracellular_ions (millimolar): 1.292367
 - cajsr in component intracellular_ions (millimolar): 1.255026
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003643
 - hf in component INa (dimensionless): 0.878857
 - hs in component INa (dimensionless): 0.878852
 - j in component INa (dimensionless): 0.878825
 - hsp in component INa (dimensionless): 0.723680
 - jp in component INa (dimensionless): 0.878806
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709011
 - hLp in component INaL (dimensionless): 0.452461
 - a in component Ito (dimensionless): 0.000626
 - iF in component Ito (dimensionless): 0.999868
 - iS in component Ito (dimensionless): 0.624564
 - ap in component Ito (dimensionless): 0.000319
 - iFp in component Ito (dimensionless): 0.999868
 - iSp in component Ito (dimensionless): 0.699880
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.937489
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999894
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001527
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.332484
 - xs1 in component IKs (dimensionless): 0.236224
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997354
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
10:55:04 (2648): called boinc_finish(0)

</stderr_txt>
]]>


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