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Task 54913462

Name HuVeMOp_20240627023041663998_ORdGradInc_k_24-Pueyo_APDR-conf_173_1
Workunit 26075065
Created 27 Jun 2024, 0:30:56 UTC
Sent 27 Jun 2024, 2:08:50 UTC
Report deadline 30 Jun 2024, 11:44:50 UTC
Received 27 Jun 2024, 6:52:42 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 227318
Run time 43 min 50 sec
CPU time 41 min 47 sec
Validate state Initial
Credit 0.00
Device peak FLOPS 5.60 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 2.95 MB
Peak swap size 391.76 GB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.20.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627023041663998_ORdGradInc_k_24-Pueyo_APDR-conf_173.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627023041663998_ORdGradInc_k_24-Pueyo_APDR-conf_173_1_r2136226675_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627023041663998_ORdGradInc_k_24-Pueyo_APDR-conf_173_1_r2136226675_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 124.830054
     * GNaL_b in INaL: 0.007741
     * Gto_b in Ito: 0.077057
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.032935
     * GKs_b in IKs: 0.001917
     * GK1_b in IK1: 0.157343
     * Gncx_b in INaCa_i: 0.000961
     * Pnak_b in INaK: 61.612033
     * GKb_b in IKb: 0.004032
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.040611
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 48020523, states[0] = 21.836321, states[40]= 0.010082
Saving checkpoint... 
Iteration: 94262049, states[0] = -94.899400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 141822442, states[0] = -94.948491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 189891535, states[0] = -94.978729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 236643240, states[0] = -64.952127, states[40]= 0.000002
Saving checkpoint... 
Iteration: 285032013, states[0] = 18.562073, states[40]= 0.006250
Saving checkpoint... 
Iteration: 331574622, states[0] = 0.492183, states[40]= 0.004417
Saving checkpoint... 
Iteration: 376665348, states[0] = -93.630286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 424749140, states[0] = -94.881833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 473869140, states[0] = -94.970632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 521253307, states[0] = -94.886992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 569650062, states[0] = -74.551123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 616138375, states[0] = -58.980132, states[40]= 0.000007
Saving checkpoint... 
Iteration: 662085174, states[0] = -6.466175, states[40]= 0.003149
Saving checkpoint... 
Iteration: 708491369, states[0] = -94.998547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 756922494, states[0] = -94.986678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 804283229, states[0] = -94.918403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 852755809, states[0] = -94.889826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 900977299, states[0] = -94.996604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 948067564, states[0] = 4.173996, states[40]= 0.004794
Saving checkpoint... 
Iteration: 995489568, states[0] = -94.998160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1043500472, states[0] = -31.309280, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1089922525, states[0] = -94.986492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1136463930, states[0] = -94.994482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1182569404, states[0] = 3.264415, states[40]= 0.004719
Saving checkpoint... 
Iteration: 1231280065, states[0] = -94.915255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1279471954, states[0] = -94.995621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1324563363, states[0] = 6.151062, states[40]= 0.004928
Saving checkpoint... 
Iteration: 1370821551, states[0] = -94.946740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1419750199, states[0] = -94.882601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1465874332, states[0] = -94.972018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1513294430, states[0] = -29.132057, states[40]= 0.000511
Saving checkpoint... 
Iteration: 1559089578, states[0] = -95.274148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1604076697, states[0] = -95.274312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1650615532, states[0] = 23.044168, states[40]= 0.019894
Saving checkpoint... 
Iteration: 1696878864, states[0] = -15.040036, states[40]= 0.001678
Saving checkpoint... 
Iteration: 1743220062, states[0] = -95.214738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1789507143, states[0] = 27.806033, states[40]= 0.096281
Saving checkpoint... 
Iteration: 1835595909, states[0] = -17.327870, states[40]= 0.001224
Saving checkpoint... 
Iteration: 1880664372, states[0] = -93.496003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1926642683, states[0] = -64.423233, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1972748603, states[0] = -94.880759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2018159445, states[0] = -89.480428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2064518669, states[0] = 22.344610, states[40]= 0.012035
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.874586
 - CaMKt in component CaMK (millimolar): 0.006949
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.872432
 - nass in component intracellular_ions (millimolar): 6.872492
 - ki in component intracellular_ions (millimolar): 145.105244
 - kss in component intracellular_ions (millimolar): 145.105223
 - cansr in component intracellular_ions (millimolar): 1.314684
 - cajsr in component intracellular_ions (millimolar): 1.276958
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003628
 - hf in component INa (dimensionless): 0.879527
 - hs in component INa (dimensionless): 0.879522
 - j in component INa (dimensionless): 0.879494
 - hsp in component INa (dimensionless): 0.724939
 - jp in component INa (dimensionless): 0.879475
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709452
 - hLp in component INaL (dimensionless): 0.451925
 - a in component Ito (dimensionless): 0.000625
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.621726
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.696312
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.933888
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999881
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001619
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.344194
 - xs1 in component IKs (dimensionless): 0.241843
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997344
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
01:52:31 (28298): called boinc_finish(0)

</stderr_txt>
]]>