Task 54907402

Name	HuVeMOp_20240627012042230474_ORdGradInc_k_24-Pueyo_APDR-conf_587_0
Workunit	26072085
Created	26 Jun 2024, 23:21:07 UTC
Sent	27 Jun 2024, 1:08:13 UTC
Report deadline	30 Jun 2024, 10:44:13 UTC
Received	27 Jun 2024, 10:36:26 UTC
Server state	Over
Outcome	Success
Client state	Done
Exit status	0 (0x00000000)
Computer ID	213754
Run time	3 hours 14 min 31 sec
CPU time	3 hours 7 min 35 sec
Validate state	Valid
Credit	59.55
Device peak FLOPS	3.69 GFLOPS
Application version	Human ventricular cell models optimization v0.02 windows_x86_64
Peak working set size	10.59 MB
Peak swap size	6.21 MB
Peak disk usage	0.28 MB
Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627012042230474_ORdGradInc_k_24-Pueyo_APDR-conf_587.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627012042230474_ORdGradInc_k_24-Pueyo_APDR-conf_587_0_r130299669_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627012042230474_ORdGradInc_k_24-Pueyo_APDR-conf_587_0_r130299669_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 112.419339
     * GNaL_b in INaL: 0.006026
     * Gto_b in Ito: 0.074867
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.033798
     * GKs_b in IKs: 0.001922
     * GK1_b in IK1: 0.160307
     * Gncx_b in INaCa_i: 0.000961
     * Pnak_b in INaK: 64.699343
     * GKb_b in IKb: 0.003777
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.045450
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12031619, states[0] = 17.461340, states[40]= 0.006365
Saving checkpoint... 
Iteration: 24139617, states[0] = -73.067880, states[40]= 0.000001
Saving checkpoint... 
Iteration: 35518000, states[0] = 22.010710, states[40]= 0.012845
Saving checkpoint... 
Iteration: 46805983, states[0] = -95.053196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58823708, states[0] = -95.058504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 70969231, states[0] = -95.099062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 83281411, states[0] = -95.022063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 95355794, states[0] = -95.065487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 107511345, states[0] = 23.973155, states[40]= 0.039923
Saving checkpoint... 
Iteration: 118945754, states[0] = -95.088361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 131045816, states[0] = 12.650970, states[40]= 0.005325
Saving checkpoint... 
Iteration: 143090155, states[0] = -14.495236, states[40]= 0.001583
Saving checkpoint... 
Iteration: 155105022, states[0] = -29.527044, states[40]= 0.000467
Saving checkpoint... 
Iteration: 166335276, states[0] = -95.052002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 178305155, states[0] = -95.034091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 189617826, states[0] = -42.900188, states[40]= 0.000081
Saving checkpoint... 
Iteration: 201005318, states[0] = 29.748050, states[40]= 0.134429
Saving checkpoint... 
Iteration: 212291139, states[0] = -95.023553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 223881109, states[0] = -95.070215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 236073179, states[0] = -0.572172, states[40]= 0.004301
Saving checkpoint... 
Iteration: 248326765, states[0] = -95.046899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260548340, states[0] = 11.623221, states[40]= 0.005249
Saving checkpoint... 
Iteration: 272751795, states[0] = -94.985440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 284871724, states[0] = -95.066875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 296554837, states[0] = 8.810940, states[40]= 0.005097
Saving checkpoint... 
Iteration: 308716897, states[0] = -94.936273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 319439555, states[0] = -95.084731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 331590762, states[0] = -15.028624, states[40]= 0.001503
Saving checkpoint... 
Iteration: 343519100, states[0] = 21.976030, states[40]= 0.011495
Saving checkpoint... 
Iteration: 355260809, states[0] = -94.995457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 367550260, states[0] = 10.807980, states[40]= 0.005199
Saving checkpoint... 
Iteration: 379852701, states[0] = -95.059364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 391757205, states[0] = -94.991512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 403996308, states[0] = -95.092980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 415493890, states[0] = -95.092704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 427327296, states[0] = -95.047027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 439532039, states[0] = 18.036088, states[40]= 0.006278
Saving checkpoint... 
Iteration: 451746629, states[0] = -94.979086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 463822176, states[0] = -95.044135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 475957651, states[0] = -95.087779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 488085265, states[0] = -9.750939, states[40]= 0.002461
Saving checkpoint... 
Iteration: 500175438, states[0] = -94.850224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 512113825, states[0] = -38.572812, states[40]= 0.000153
Saving checkpoint... 
Iteration: 524297833, states[0] = -95.028274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 536590799, states[0] = -15.065002, states[40]= 0.001498
Saving checkpoint... 
Iteration: 548887627, states[0] = -95.071971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 560736320, states[0] = -94.965577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 572227412, states[0] = -94.952760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 584371248, states[0] = -95.066514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 595779745, states[0] = -95.013700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 607545570, states[0] = 12.781563, states[40]= 0.005333
Saving checkpoint... 
Iteration: 618946682, states[0] = -95.085857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 630496586, states[0] = -95.092883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 642028547, states[0] = 19.230316, states[40]= 0.006832
Saving checkpoint... 
Iteration: 653367033, states[0] = -95.064935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 657565063, states[0] = 3.966926, states[40]= 0.004807
Saving checkpoint... 
Iteration: 668344669, states[0] = -95.055630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 680535778, states[0] = 16.669955, states[40]= 0.005882
Saving checkpoint... 
Iteration: 692513972, states[0] = 23.235196, states[40]= 0.023608
Saving checkpoint... 
Iteration: 704588310, states[0] = -12.618113, states[40]= 0.001894
Saving checkpoint... 
Iteration: 715578069, states[0] = -3.845228, states[40]= 0.003733
Saving checkpoint... 
Iteration: 727547940, states[0] = 11.792650, states[40]= 0.005260
Saving checkpoint... 
Iteration: 739413663, states[0] = -95.078955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 751508327, states[0] = 25.524848, states[40]= 0.077805
Saving checkpoint... 
Iteration: 763621867, states[0] = -47.388279, states[40]= 0.000041
Saving checkpoint... 
Iteration: 775780982, states[0] = -95.014680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 788092126, states[0] = -16.392380, states[40]= 0.001322
Saving checkpoint... 
Iteration: 800319345, states[0] = -95.042295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 812482080, states[0] = -95.091068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 823753473, states[0] = -94.987048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 834527959, states[0] = 19.422645, states[40]= 0.006952
Saving checkpoint... 
Iteration: 846655444, states[0] = -92.466891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 858881608, states[0] = -95.069896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 870309951, states[0] = -95.036436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 882567414, states[0] = 2.738600, states[40]= 0.004700
Saving checkpoint... 
Iteration: 894616550, states[0] = -41.486705, states[40]= 0.000101
Saving checkpoint... 
Iteration: 906945169, states[0] = -95.085426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 919077486, states[0] = -3.425950, states[40]= 0.003814
Saving checkpoint... 
Iteration: 930598838, states[0] = -23.185829, states[40]= 0.000773
Saving checkpoint... 
Iteration: 942862293, states[0] = -95.062964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 955160929, states[0] = -94.361554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 967400514, states[0] = -95.075461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 978487009, states[0] = -95.091584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 989731406, states[0] = -94.958409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1001423759, states[0] = -95.081125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1013559457, states[0] = 6.703510, states[40]= 0.004989
Saving checkpoint... 
Iteration: 1024914628, states[0] = -95.079025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1037090356, states[0] = -14.624488, states[40]= 0.001563
Saving checkpoint... 
Iteration: 1047690811, states[0] = -94.887216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1059930939, states[0] = -95.082612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1071933810, states[0] = -95.083185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1084074401, states[0] = -1.339914, states[40]= 0.004183
Saving checkpoint... 
Iteration: 1096062450, states[0] = 5.271934, states[40]= 0.004903
Saving checkpoint... 
Iteration: 1107825020, states[0] = -95.045385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1119260633, states[0] = -94.994835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1131414841, states[0] = -95.079016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1143435804, states[0] = -95.083539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1154757131, states[0] = -94.990998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1165452124, states[0] = -95.086487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1177568091, states[0] = 2.373824, states[40]= 0.004664
Saving checkpoint... 
Iteration: 1188875722, states[0] = -95.067744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1200980794, states[0] = -95.090686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1212822949, states[0] = -95.044156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1225135663, states[0] = -63.863967, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1237286985, states[0] = -95.019478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1249455153, states[0] = -95.086942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1261456675, states[0] = -95.087182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1273619350, states[0] = -44.558188, states[40]= 0.000063
Saving checkpoint... 
Iteration: 1285780773, states[0] = -95.014211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1297773103, states[0] = -95.007259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1309092322, states[0] = -16.589078, states[40]= 0.001298
Saving checkpoint... 
Iteration: 1316689752, states[0] = -94.884879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1328459991, states[0] = -95.087669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1340581898, states[0] = -6.818139, states[40]= 0.003104
Saving checkpoint... 
Iteration: 1352751103, states[0] = -94.983984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1364868876, states[0] = -95.065216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1376969941, states[0] = -95.089123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1388599725, states[0] = -24.085449, states[40]= 0.000727
Saving checkpoint... 
Iteration: 1400778885, states[0] = -95.012487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1412532943, states[0] = 17.713622, states[40]= 0.006168
Saving checkpoint... 
Iteration: 1424455677, states[0] = -95.086929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1435328045, states[0] = -95.046868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1447292729, states[0] = -95.023919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1458494838, states[0] = -95.092224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1470720637, states[0] = -94.941720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1482814026, states[0] = -95.038683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1494928203, states[0] = -95.081801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1506347346, states[0] = 9.207213, states[40]= 0.005822
Saving checkpoint... 
Iteration: 1518372114, states[0] = -8.900967, states[40]= 0.002933
Saving checkpoint... 
Iteration: 1530453785, states[0] = -95.132400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1541648838, states[0] = -95.318703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1553740661, states[0] = 12.029691, states[40]= 0.006306
Saving checkpoint... 
Iteration: 1565111222, states[0] = 24.640387, states[40]= 0.041966
Saving checkpoint... 
Iteration: 1577219389, states[0] = -68.891570, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1588124551, states[0] = -95.306471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1600114003, states[0] = -95.293101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1611407972, states[0] = -53.369299, states[40]= 0.000017
Saving checkpoint... 
Iteration: 1622315166, states[0] = -95.296570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1633948647, states[0] = -95.129475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1645488716, states[0] = -95.372073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1657535093, states[0] = 14.658150, states[40]= 0.006821
Saving checkpoint... 
Iteration: 1668844861, states[0] = -95.335331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1680917906, states[0] = 22.011910, states[40]= 0.014578
Saving checkpoint... 
Iteration: 1692810548, states[0] = -95.291039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1703068658, states[0] = -95.357882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1714514928, states[0] = 23.079517, states[40]= 0.021598
Saving checkpoint... 
Iteration: 1726457379, states[0] = -95.348078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1738371982, states[0] = -95.216303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1749776209, states[0] = -95.226076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1761811991, states[0] = -95.293390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1773368925, states[0] = -7.536540, states[40]= 0.003299
Saving checkpoint... 
Iteration: 1784578121, states[0] = -95.230354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1796542968, states[0] = -94.986873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1808662137, states[0] = -94.778409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1820606829, states[0] = -33.906072, states[40]= 0.000288
Saving checkpoint... 
Iteration: 1832606427, states[0] = -32.729601, states[40]= 0.000330
Saving checkpoint... 
Iteration: 1844036820, states[0] = 15.983016, states[40]= 0.005794
Saving checkpoint... 
Iteration: 1856025872, states[0] = 19.918111, states[40]= 0.007443
Saving checkpoint... 
Iteration: 1867932002, states[0] = -95.092736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1879908669, states[0] = -95.084443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1890419882, states[0] = -95.085210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1902373024, states[0] = -95.070280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1913929624, states[0] = -95.084641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1925964550, states[0] = -95.089995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1937908832, states[0] = -95.078483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1949969008, states[0] = -95.089644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1961707185, states[0] = -94.919129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1971911996, states[0] = -95.078362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1983668929, states[0] = -94.802766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1994861362, states[0] = -95.062250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2005807405, states[0] = -95.034290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2017952567, states[0] = -95.086186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2028459612, states[0] = -95.087281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2040494683, states[0] = -95.091912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2052586397, states[0] = -10.798726, states[40]= 0.002244
Saving checkpoint... 
Iteration: 2064666029, states[0] = -94.739262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2076604748, states[0] = -29.193577, states[40]= 0.000483
Saving checkpoint... 
Iteration: 2088514888, states[0] = 23.006338, states[40]= 0.020109
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.968270
 - CaMKt in component CaMK (millimolar): 0.006723
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.703360
 - nass in component intracellular_ions (millimolar): 6.703420
 - ki in component intracellular_ions (millimolar): 145.276572
 - kss in component intracellular_ions (millimolar): 145.276552
 - cansr in component intracellular_ions (millimolar): 1.304532
 - cajsr in component intracellular_ions (millimolar): 1.267482
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003594
 - hf in component INa (dimensionless): 0.881148
 - hs in component INa (dimensionless): 0.881144
 - j in component INa (dimensionless): 0.881118
 - hsp in component INa (dimensionless): 0.727999
 - jp in component INa (dimensionless): 0.881100
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.713466
 - hLp in component INaL (dimensionless): 0.459494
 - a in component Ito (dimensionless): 0.000621
 - iF in component Ito (dimensionless): 0.999871
 - iS in component Ito (dimensionless): 0.629093
 - ap in component Ito (dimensionless): 0.000316
 - iFp in component Ito (dimensionless): 0.999871
 - iSp in component Ito (dimensionless): 0.705221
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.937702
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999897
 - jca in component ICaL (dimensionless): 0.999981
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001586
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.332346
 - xs1 in component IKs (dimensionless): 0.232508
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997320
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
02:36:03 (7236): called boinc_finish(0)

</stderr_txt>
]]>