𝕏

Task 54902791

Name HuVeMOp_20240627004113829118_ORdGradInc_k_24-Pueyo_APDR-conf_823_1
Workunit 26069803
Created 26 Jun 2024, 22:41:23 UTC
Sent 27 Jun 2024, 0:15:21 UTC
Report deadline 30 Jun 2024, 9:51:21 UTC
Received 27 Jun 2024, 2:42:16 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241023
Run time 2 hours 26 min 37 sec
CPU time 2 hours 24 min 34 sec
Validate state Valid
Credit 61.73
Device peak FLOPS 1.00 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.25 MB
Peak swap size 3.82 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627004113829118_ORdGradInc_k_24-Pueyo_APDR-conf_823.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627004113829118_ORdGradInc_k_24-Pueyo_APDR-conf_823_1_r2004604145_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627004113829118_ORdGradInc_k_24-Pueyo_APDR-conf_823_1_r2004604145_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 105.180520
     * GNaL_b in INaL: 0.005655
     * Gto_b in Ito: 0.079325
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.032856
     * GKs_b in IKs: 0.001887
     * GK1_b in IK1: 0.145349
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 70.049071
     * GKb_b in IKb: 0.003855
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.054141
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 15028695, states[0] = 18.044712, states[40]= 0.006581
Saving checkpoint... 
Iteration: 29662667, states[0] = -94.225518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 44074667, states[0] = -1.765378, states[40]= 0.004044
Saving checkpoint... 
Iteration: 58252821, states[0] = -94.908602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 72852650, states[0] = -94.979456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 87180207, states[0] = -94.752563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 101708876, states[0] = -94.819157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 116120333, states[0] = -43.246991, states[40]= 0.000074
Saving checkpoint... 
Iteration: 130594668, states[0] = -17.363852, states[40]= 0.001184
Saving checkpoint... 
Iteration: 145057416, states[0] = 7.900860, states[40]= 0.004922
Saving checkpoint... 
Iteration: 158648633, states[0] = -76.604606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 172617158, states[0] = -39.716917, states[40]= 0.000126
Saving checkpoint... 
Iteration: 186430156, states[0] = -94.989006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 200970551, states[0] = -94.996276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 215569738, states[0] = 2.055403, states[40]= 0.004522
Saving checkpoint... 
Iteration: 229757288, states[0] = -94.888291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 244317967, states[0] = -94.943528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 259064274, states[0] = 4.808065, states[40]= 0.004752
Saving checkpoint... 
Iteration: 273672139, states[0] = -94.621181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 288300980, states[0] = -94.931213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 302559579, states[0] = 6.978240, states[40]= 0.004877
Saving checkpoint... 
Iteration: 316895580, states[0] = -94.979196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 331930702, states[0] = -94.988443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346792641, states[0] = -94.924348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 361659461, states[0] = -91.331951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 376037794, states[0] = 15.858514, states[40]= 0.005545
Saving checkpoint... 
Iteration: 390500748, states[0] = 44.020015, states[40]= 0.008926
Saving checkpoint... 
Iteration: 404994875, states[0] = -94.999049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 419352417, states[0] = -94.962553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 433925127, states[0] = -94.987105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 448422816, states[0] = -94.986549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 462953843, states[0] = -94.992975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 477512190, states[0] = 23.081927, states[40]= 0.032783
Saving checkpoint... 
Iteration: 492338180, states[0] = -94.955342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 507011486, states[0] = 23.266741, states[40]= 0.038058
Saving checkpoint... 
Iteration: 521661669, states[0] = -92.748376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 536459138, states[0] = -94.993854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 551493839, states[0] = -94.998841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 566280776, states[0] = -94.913480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 581236918, states[0] = -94.860138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 596176857, states[0] = -94.713763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 611405696, states[0] = -94.982007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 626473526, states[0] = -94.996080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641505065, states[0] = 29.170593, states[40]= 0.137358
Saving checkpoint... 
Iteration: 656396740, states[0] = -94.979349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 671334218, states[0] = -94.953062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 686123699, states[0] = -46.573151, states[40]= 0.000045
Saving checkpoint... 
Iteration: 700619660, states[0] = -42.268359, states[40]= 0.000086
Saving checkpoint... 
Iteration: 715640928, states[0] = -66.023320, states[40]= 0.000002
Saving checkpoint... 
Iteration: 730816804, states[0] = -94.942367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 746167877, states[0] = -94.354286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 761441217, states[0] = -94.990416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 776847164, states[0] = -94.959821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 791681448, states[0] = -94.745396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 806095776, states[0] = -18.308734, states[40]= 0.001091
Saving checkpoint... 
Iteration: 820733682, states[0] = -94.855037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 835478324, states[0] = -94.996654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 850194841, states[0] = -94.782502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 864973435, states[0] = -94.995933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 879471510, states[0] = -94.995638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 893971501, states[0] = -94.995628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 908409047, states[0] = -94.982769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 922801042, states[0] = -94.930871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 937299428, states[0] = -94.929592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 951767339, states[0] = -94.899406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 966399123, states[0] = -94.979897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 981289926, states[0] = -94.921641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 996290985, states[0] = -94.922555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1011302022, states[0] = -94.931584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1026381338, states[0] = -94.974054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1041351771, states[0] = -94.961898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1056689653, states[0] = -94.770588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1071883826, states[0] = -94.974901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1086826383, states[0] = -94.948259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1101813418, states[0] = -94.939862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1116890021, states[0] = -94.976963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1132100597, states[0] = -23.082964, states[40]= 0.000767
Saving checkpoint... 
Iteration: 1146755676, states[0] = -94.885603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1161559351, states[0] = 7.080711, states[40]= 0.004882
Saving checkpoint... 
Iteration: 1176481355, states[0] = -94.996884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1191341674, states[0] = -94.956802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1206061939, states[0] = 5.906423, states[40]= 0.004820
Saving checkpoint... 
Iteration: 1220905669, states[0] = -94.981657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1235813852, states[0] = -94.940085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1251175750, states[0] = -94.700039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1266443732, states[0] = -94.990632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1281800087, states[0] = -94.929919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1297061862, states[0] = 5.941968, states[40]= 0.004822
Saving checkpoint... 
Iteration: 1312373814, states[0] = -94.971122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1327688353, states[0] = -94.767246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1343114397, states[0] = -36.843964, states[40]= 0.000189
Saving checkpoint... 
Iteration: 1358430831, states[0] = -94.987886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1373616288, states[0] = -38.771273, states[40]= 0.000144
Saving checkpoint... 
Iteration: 1388975201, states[0] = -94.995897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1404240456, states[0] = -94.864921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1419604729, states[0] = -27.177762, states[40]= 0.000569
Saving checkpoint... 
Iteration: 1434989381, states[0] = -94.997794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1450475473, states[0] = -94.995902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1465725189, states[0] = -94.840861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1480931907, states[0] = -94.988054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1495857493, states[0] = -94.964272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1510866473, states[0] = -2.635770, states[40]= 0.004270
Saving checkpoint... 
Iteration: 1525990203, states[0] = -95.147695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1541176661, states[0] = -13.749271, states[40]= 0.001866
Saving checkpoint... 
Iteration: 1556618871, states[0] = -95.224619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1571972662, states[0] = -95.293958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1586830596, states[0] = -82.636756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1601786339, states[0] = -25.635217, states[40]= 0.000653
Saving checkpoint... 
Iteration: 1616939677, states[0] = -95.266696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1632111024, states[0] = -54.842797, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1647132819, states[0] = -86.636902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1661750088, states[0] = 6.770297, states[40]= 0.005584
Saving checkpoint... 
Iteration: 1676240920, states[0] = -93.848688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1691170032, states[0] = -7.709175, states[40]= 0.003192
Saving checkpoint... 
Iteration: 1706157857, states[0] = 2.026516, states[40]= 0.005091
Saving checkpoint... 
Iteration: 1721150195, states[0] = 6.702200, states[40]= 0.005578
Saving checkpoint... 
Iteration: 1735962759, states[0] = -95.117384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1750697862, states[0] = -95.202653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1765466766, states[0] = -95.297791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1780335949, states[0] = -90.689696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1795484468, states[0] = -95.312608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1810676343, states[0] = -94.783118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1825800541, states[0] = -94.970174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1841021200, states[0] = 20.895784, states[40]= 0.009238
Saving checkpoint... 
Iteration: 1856193402, states[0] = -94.795653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1871193357, states[0] = -94.789547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1886324626, states[0] = -94.953626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1901608124, states[0] = -30.781436, states[40]= 0.000404
Saving checkpoint... 
Iteration: 1916606409, states[0] = -28.993140, states[40]= 0.000484
Saving checkpoint... 
Iteration: 1931486977, states[0] = -94.999026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1946417186, states[0] = -94.985487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1961168754, states[0] = -94.440052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1976142360, states[0] = -67.845128, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1991132047, states[0] = -55.776667, states[40]= 0.000010
Saving checkpoint... 
Iteration: 2006335526, states[0] = -94.953208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2021187690, states[0] = -94.765263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2036259050, states[0] = -94.889278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2051232922, states[0] = -94.853164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2065999857, states[0] = -94.998689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2080901709, states[0] = -94.980015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2095612144, states[0] = -34.570993, states[40]= 0.000257
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.874539
 - CaMKt in component CaMK (millimolar): 0.006644
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.536147
 - nass in component intracellular_ions (millimolar): 6.536207
 - ki in component intracellular_ions (millimolar): 145.446424
 - kss in component intracellular_ions (millimolar): 145.446404
 - cansr in component intracellular_ions (millimolar): 1.292285
 - cajsr in component intracellular_ions (millimolar): 1.254987
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003628
 - hf in component INa (dimensionless): 0.879526
 - hs in component INa (dimensionless): 0.879522
 - j in component INa (dimensionless): 0.879493
 - hsp in component INa (dimensionless): 0.724937
 - jp in component INa (dimensionless): 0.879474
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709951
 - hLp in component INaL (dimensionless): 0.453367
 - a in component Ito (dimensionless): 0.000625
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.625049
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.700386
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.937254
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999894
 - jca in component ICaL (dimensionless): 0.999980
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001532
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.331449
 - xs1 in component IKs (dimensionless): 0.235602
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997344
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
04:42:04 (538774): called boinc_finish(0)

</stderr_txt>
]]>