Task 54894081
| Name | HuVeMOp_20240626223132141174_ORdGradInc_k_24-Pueyo_APDR-conf_88_1 |
| Workunit | 26065497 |
| Created | 26 Jun 2024, 20:32:22 UTC |
| Sent | 26 Jun 2024, 23:03:39 UTC |
| Report deadline | 30 Jun 2024, 8:39:39 UTC |
| Received | 27 Jun 2024, 16:58:34 UTC |
| Server state | Over |
| Outcome | Success |
| Client state | Done |
| Exit status | 0 (0x00000000) |
| Computer ID | 216880 |
| Run time | 57 min 33 sec |
| CPU time | 54 min 50 sec |
| Validate state | Valid |
| Credit | 58.56 |
| Device peak FLOPS | 4.73 GFLOPS |
| Application version | Human ventricular cell models optimization v0.02 arm64-apple-darwin |
| Peak working set size | 2.97 MB |
| Peak swap size | 391.75 GB |
| Peak disk usage | 0.27 MB |
Stderr output
<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>
===============================================================
--- DENIS Myocyte Simulator ---
Version 0.22 - Beta
---------------------------------------------------------------
https://denis.usj.es
Universidad San Jorge
===============================================================
Boinc file names:
- INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626223132141174_ORdGradInc_k_24-Pueyo_APDR-conf_88.xml
- OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626223132141174_ORdGradInc_k_24-Pueyo_APDR-conf_88_1_r1352467757_0
- MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626223132141174_ORdGradInc_k_24-Pueyo_APDR-conf_88_1_r1352467757_1
- CHECKPOINT_FILE: denis_checkpoint
- CHECKPOINT_FILE_2: denis_checkpoint_2
Configuration:
- Model name: ORd_SS_biphasic
- Solver: FE
- Simulation time: 4200000.000000
- dt: 0.002000
- Constants to change: 21
* GNa in INa: 98.567807
* GNaL_b in INaL: 0.005618
* Gto_b in Ito: 0.073610
* PCa_b in ICaL: 0.000081
* GKr_b in IKr: 0.034050
* GKs_b in IKs: 0.001875
* GK1_b in IK1: 0.144311
* Gncx_b in INaCa_i: 0.000960
* Pnak_b in INaK: 68.003345
* GKb_b in IKb: 0.003769
* PNab in INab: 0.000000
* PCab in ICab: 0.000000
* GpCa in IpCa: 0.047131
* celltype in environment: 0.000000
* nCL_1 in membrane: 1000.000000
* CL_1 in membrane: 600.000000
* nCL_2 in membrane: 600.000000
* CL_2 in membrane: 1000.000000
* cao in extracellular: 1.000000
* ko in extracellular: 4.000000
* nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint...
Iteration: 35472480, states[0] = -95.033383, states[40]= 0.000000
===============================================================
--- DENIS Myocyte Simulator ---
Version 0.22 - Beta
---------------------------------------------------------------
https://denis.usj.es
Universidad San Jorge
===============================================================
Boinc file names:
- INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626223132141174_ORdGradInc_k_24-Pueyo_APDR-conf_88.xml
- OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626223132141174_ORdGradInc_k_24-Pueyo_APDR-conf_88_1_r1352467757_0
- MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626223132141174_ORdGradInc_k_24-Pueyo_APDR-conf_88_1_r1352467757_1
- CHECKPOINT_FILE: denis_checkpoint
- CHECKPOINT_FILE_2: denis_checkpoint_2
Configuration:
- Model name: ORd_SS_biphasic
- Solver: FE
- Simulation time: 4200000.000000
- dt: 0.002000
- Constants to change: 21
* GNa in INa: 98.567807
* GNaL_b in INaL: 0.005618
* Gto_b in Ito: 0.073610
* PCa_b in ICaL: 0.000081
* GKr_b in IKr: 0.034050
* GKs_b in IKs: 0.001875
* GK1_b in IK1: 0.144311
* Gncx_b in INaCa_i: 0.000960
* Pnak_b in INaK: 68.003345
* GKb_b in IKb: 0.003769
* PNab in INab: 0.000000
* PCab in ICab: 0.000000
* GpCa in IpCa: 0.047131
* celltype in environment: 0.000000
* nCL_1 in membrane: 1000.000000
* CL_1 in membrane: 600.000000
* nCL_2 in membrane: 600.000000
* CL_2 in membrane: 1000.000000
* cao in extracellular: 1.000000
* ko in extracellular: 4.000000
* nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
- Iteration number: 35472480
Loading states...
- states[0]: -87.000000 (Before loading)
- states[40]: 0.000000 (Before loading)
- states[0]: -95.033383 (After loading)
- states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
===============================================================
--- DENIS Myocyte Simulator ---
Version 0.22 - Beta
---------------------------------------------------------------
https://denis.usj.es
Universidad San Jorge
===============================================================
Boinc file names:
- INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626223132141174_ORdGradInc_k_24-Pueyo_APDR-conf_88.xml
- OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626223132141174_ORdGradInc_k_24-Pueyo_APDR-conf_88_1_r1352467757_0
- MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626223132141174_ORdGradInc_k_24-Pueyo_APDR-conf_88_1_r1352467757_1
- CHECKPOINT_FILE: denis_checkpoint
- CHECKPOINT_FILE_2: denis_checkpoint_2
Configuration:
- Model name: ORd_SS_biphasic
- Solver: FE
- Simulation time: 4200000.000000
- dt: 0.002000
- Constants to change: 21
* GNa in INa: 98.567807
* GNaL_b in INaL: 0.005618
* Gto_b in Ito: 0.073610
* PCa_b in ICaL: 0.000081
* GKr_b in IKr: 0.034050
* GKs_b in IKs: 0.001875
* GK1_b in IK1: 0.144311
* Gncx_b in INaCa_i: 0.000960
* Pnak_b in INaK: 68.003345
* GKb_b in IKb: 0.003769
* PNab in INab: 0.000000
* PCab in ICab: 0.000000
* GpCa in IpCa: 0.047131
* celltype in environment: 0.000000
* nCL_1 in membrane: 1000.000000
* CL_1 in membrane: 600.000000
* nCL_2 in membrane: 600.000000
* CL_2 in membrane: 1000.000000
* cao in extracellular: 1.000000
* ko in extracellular: 4.000000
* nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
- Iteration number: 35472480
Loading states...
- states[0]: -87.000000 (Before loading)
- states[40]: 0.000000 (Before loading)
- states[0]: -95.033383 (After loading)
- states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
===============================================================
--- DENIS Myocyte Simulator ---
Version 0.22 - Beta
---------------------------------------------------------------
https://denis.usj.es
Universidad San Jorge
===============================================================
Boinc file names:
- INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626223132141174_ORdGradInc_k_24-Pueyo_APDR-conf_88.xml
- OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626223132141174_ORdGradInc_k_24-Pueyo_APDR-conf_88_1_r1352467757_0
- MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626223132141174_ORdGradInc_k_24-Pueyo_APDR-conf_88_1_r1352467757_1
- CHECKPOINT_FILE: denis_checkpoint
- CHECKPOINT_FILE_2: denis_checkpoint_2
Configuration:
- Model name: ORd_SS_biphasic
- Solver: FE
- Simulation time: 4200000.000000
- dt: 0.002000
- Constants to change: 21
* GNa in INa: 98.567807
* GNaL_b in INaL: 0.005618
* Gto_b in Ito: 0.073610
* PCa_b in ICaL: 0.000081
* GKr_b in IKr: 0.034050
* GKs_b in IKs: 0.001875
* GK1_b in IK1: 0.144311
* Gncx_b in INaCa_i: 0.000960
* Pnak_b in INaK: 68.003345
* GKb_b in IKb: 0.003769
* PNab in INab: 0.000000
* PCab in ICab: 0.000000
* GpCa in IpCa: 0.047131
* celltype in environment: 0.000000
* nCL_1 in membrane: 1000.000000
* CL_1 in membrane: 600.000000
* nCL_2 in membrane: 600.000000
* CL_2 in membrane: 1000.000000
* cao in extracellular: 1.000000
* ko in extracellular: 4.000000
* nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
- Iteration number: 35472480
Loading states...
- states[0]: -87.000000 (Before loading)
- states[40]: 0.000000 (Before loading)
- states[0]: -95.033383 (After loading)
- states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint...
Iteration: 84576696, states[0] = -3.161724, states[40]= 0.003824
Saving checkpoint...
Iteration: 143505384, states[0] = 29.046576, states[40]= 0.129771
===============================================================
--- DENIS Myocyte Simulator ---
Version 0.22 - Beta
---------------------------------------------------------------
https://denis.usj.es
Universidad San Jorge
===============================================================
Boinc file names:
- INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626223132141174_ORdGradInc_k_24-Pueyo_APDR-conf_88.xml
- OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626223132141174_ORdGradInc_k_24-Pueyo_APDR-conf_88_1_r1352467757_0
- MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626223132141174_ORdGradInc_k_24-Pueyo_APDR-conf_88_1_r1352467757_1
- CHECKPOINT_FILE: denis_checkpoint
- CHECKPOINT_FILE_2: denis_checkpoint_2
Configuration:
- Model name: ORd_SS_biphasic
- Solver: FE
- Simulation time: 4200000.000000
- dt: 0.002000
- Constants to change: 21
* GNa in INa: 98.567807
* GNaL_b in INaL: 0.005618
* Gto_b in Ito: 0.073610
* PCa_b in ICaL: 0.000081
* GKr_b in IKr: 0.034050
* GKs_b in IKs: 0.001875
* GK1_b in IK1: 0.144311
* Gncx_b in INaCa_i: 0.000960
* Pnak_b in INaK: 68.003345
* GKb_b in IKb: 0.003769
* PNab in INab: 0.000000
* PCab in ICab: 0.000000
* GpCa in IpCa: 0.047131
* celltype in environment: 0.000000
* nCL_1 in membrane: 1000.000000
* CL_1 in membrane: 600.000000
* nCL_2 in membrane: 600.000000
* CL_2 in membrane: 1000.000000
* cao in extracellular: 1.000000
* ko in extracellular: 4.000000
* nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
- Iteration number: 143505384
Loading states...
- states[0]: -87.000000 (Before loading)
- states[40]: 0.000000 (Before loading)
- states[0]: 29.046576 (After loading)
- states[40]: 0.129771 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint...
Iteration: 170675767, states[0] = -94.718448, states[40]= 0.000000
Saving checkpoint...
Iteration: 216935926, states[0] = -94.981226, states[40]= 0.000000
Saving checkpoint...
Iteration: 269054012, states[0] = 9.169952, states[40]= 0.005045
Saving checkpoint...
Iteration: 332864889, states[0] = -94.959568, states[40]= 0.000000
Saving checkpoint...
Iteration: 383357696, states[0] = -94.956453, states[40]= 0.000000
Saving checkpoint...
Iteration: 443677774, states[0] = -94.728970, states[40]= 0.000000
Saving checkpoint...
Iteration: 501011664, states[0] = 23.807950, states[40]= 0.036025
Saving checkpoint...
Iteration: 551844078, states[0] = -94.949906, states[40]= 0.000000
Saving checkpoint...
Iteration: 610163444, states[0] = -94.173267, states[40]= 0.000000
Saving checkpoint...
Iteration: 668627213, states[0] = -53.513791, states[40]= 0.000014
Saving checkpoint...
Iteration: 724429656, states[0] = -94.979340, states[40]= 0.000000
Saving checkpoint...
Iteration: 780067170, states[0] = 2.884049, states[40]= 0.004653
Saving checkpoint...
Iteration: 840191327, states[0] = -94.768113, states[40]= 0.000000
===============================================================
--- DENIS Myocyte Simulator ---
Version 0.22 - Beta
---------------------------------------------------------------
https://denis.usj.es
Universidad San Jorge
===============================================================
Boinc file names:
- INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626223132141174_ORdGradInc_k_24-Pueyo_APDR-conf_88.xml
- OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626223132141174_ORdGradInc_k_24-Pueyo_APDR-conf_88_1_r1352467757_0
- MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626223132141174_ORdGradInc_k_24-Pueyo_APDR-conf_88_1_r1352467757_1
- CHECKPOINT_FILE: denis_checkpoint
- CHECKPOINT_FILE_2: denis_checkpoint_2
Configuration:
- Model name: ORd_SS_biphasic
- Solver: FE
- Simulation time: 4200000.000000
- dt: 0.002000
- Constants to change: 21
* GNa in INa: 98.567807
* GNaL_b in INaL: 0.005618
* Gto_b in Ito: 0.073610
* PCa_b in ICaL: 0.000081
* GKr_b in IKr: 0.034050
* GKs_b in IKs: 0.001875
* GK1_b in IK1: 0.144311
* Gncx_b in INaCa_i: 0.000960
* Pnak_b in INaK: 68.003345
* GKb_b in IKb: 0.003769
* PNab in INab: 0.000000
* PCab in ICab: 0.000000
* GpCa in IpCa: 0.047131
* celltype in environment: 0.000000
* nCL_1 in membrane: 1000.000000
* CL_1 in membrane: 600.000000
* nCL_2 in membrane: 600.000000
* CL_2 in membrane: 1000.000000
* cao in extracellular: 1.000000
* ko in extracellular: 4.000000
* nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
- Iteration number: 840191327
Loading states...
- states[0]: -87.000000 (Before loading)
- states[40]: 0.000000 (Before loading)
- states[0]: -94.768113 (After loading)
- states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint...
Iteration: 885489367, states[0] = -94.989440, states[40]= 0.000000
Saving checkpoint...
Iteration: 935028368, states[0] = 19.305412, states[40]= 0.006758
Saving checkpoint...
Iteration: 988024569, states[0] = 20.496048, states[40]= 0.007757
Saving checkpoint...
Iteration: 1030138541, states[0] = -66.862331, states[40]= 0.000001
Saving checkpoint...
Iteration: 1081326780, states[0] = -94.940083, states[40]= 0.000000
Saving checkpoint...
Iteration: 1130901061, states[0] = -94.971772, states[40]= 0.000000
Saving checkpoint...
Iteration: 1178620158, states[0] = -45.584218, states[40]= 0.000051
Saving checkpoint...
Iteration: 1216126822, states[0] = -53.068919, states[40]= 0.000015
Saving checkpoint...
Iteration: 1246558806, states[0] = 7.007027, states[40]= 0.004940
Saving checkpoint...
Iteration: 1301587054, states[0] = -11.403128, states[40]= 0.002098
Saving checkpoint...
Iteration: 1356819447, states[0] = -94.935375, states[40]= 0.000000
===============================================================
--- DENIS Myocyte Simulator ---
Version 0.22 - Beta
---------------------------------------------------------------
https://denis.usj.es
Universidad San Jorge
===============================================================
Boinc file names:
- INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626223132141174_ORdGradInc_k_24-Pueyo_APDR-conf_88.xml
- OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626223132141174_ORdGradInc_k_24-Pueyo_APDR-conf_88_1_r1352467757_0
- MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626223132141174_ORdGradInc_k_24-Pueyo_APDR-conf_88_1_r1352467757_1
- CHECKPOINT_FILE: denis_checkpoint
- CHECKPOINT_FILE_2: denis_checkpoint_2
Configuration:
- Model name: ORd_SS_biphasic
- Solver: FE
- Simulation time: 4200000.000000
- dt: 0.002000
- Constants to change: 21
* GNa in INa: 98.567807
* GNaL_b in INaL: 0.005618
* Gto_b in Ito: 0.073610
* PCa_b in ICaL: 0.000081
* GKr_b in IKr: 0.034050
* GKs_b in IKs: 0.001875
* GK1_b in IK1: 0.144311
* Gncx_b in INaCa_i: 0.000960
* Pnak_b in INaK: 68.003345
* GKb_b in IKb: 0.003769
* PNab in INab: 0.000000
* PCab in ICab: 0.000000
* GpCa in IpCa: 0.047131
* celltype in environment: 0.000000
* nCL_1 in membrane: 1000.000000
* CL_1 in membrane: 600.000000
* nCL_2 in membrane: 600.000000
* CL_2 in membrane: 1000.000000
* cao in extracellular: 1.000000
* ko in extracellular: 4.000000
* nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
- Iteration number: 1356819447
Loading states...
- states[0]: -87.000000 (Before loading)
- states[40]: 0.000000 (Before loading)
- states[0]: -94.935375 (After loading)
- states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint...
Iteration: 1413100263, states[0] = -24.729805, states[40]= 0.000676
===============================================================
--- DENIS Myocyte Simulator ---
Version 0.22 - Beta
---------------------------------------------------------------
https://denis.usj.es
Universidad San Jorge
===============================================================
Boinc file names:
- INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626223132141174_ORdGradInc_k_24-Pueyo_APDR-conf_88.xml
- OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626223132141174_ORdGradInc_k_24-Pueyo_APDR-conf_88_1_r1352467757_0
- MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626223132141174_ORdGradInc_k_24-Pueyo_APDR-conf_88_1_r1352467757_1
- CHECKPOINT_FILE: denis_checkpoint
- CHECKPOINT_FILE_2: denis_checkpoint_2
Configuration:
- Model name: ORd_SS_biphasic
- Solver: FE
- Simulation time: 4200000.000000
- dt: 0.002000
- Constants to change: 21
* GNa in INa: 98.567807
* GNaL_b in INaL: 0.005618
* Gto_b in Ito: 0.073610
* PCa_b in ICaL: 0.000081
* GKr_b in IKr: 0.034050
* GKs_b in IKs: 0.001875
* GK1_b in IK1: 0.144311
* Gncx_b in INaCa_i: 0.000960
* Pnak_b in INaK: 68.003345
* GKb_b in IKb: 0.003769
* PNab in INab: 0.000000
* PCab in ICab: 0.000000
* GpCa in IpCa: 0.047131
* celltype in environment: 0.000000
* nCL_1 in membrane: 1000.000000
* CL_1 in membrane: 600.000000
* nCL_2 in membrane: 600.000000
* CL_2 in membrane: 1000.000000
* cao in extracellular: 1.000000
* ko in extracellular: 4.000000
* nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
- Iteration number: 1413100263
Loading states...
- states[0]: -87.000000 (Before loading)
- states[40]: 0.000000 (Before loading)
- states[0]: -24.729805 (After loading)
- states[40]: 0.000676 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint...
Iteration: 1471280681, states[0] = -94.904782, states[40]= 0.000000
===============================================================
--- DENIS Myocyte Simulator ---
Version 0.22 - Beta
---------------------------------------------------------------
https://denis.usj.es
Universidad San Jorge
===============================================================
Boinc file names:
- INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626223132141174_ORdGradInc_k_24-Pueyo_APDR-conf_88.xml
- OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626223132141174_ORdGradInc_k_24-Pueyo_APDR-conf_88_1_r1352467757_0
- MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626223132141174_ORdGradInc_k_24-Pueyo_APDR-conf_88_1_r1352467757_1
- CHECKPOINT_FILE: denis_checkpoint
- CHECKPOINT_FILE_2: denis_checkpoint_2
Configuration:
- Model name: ORd_SS_biphasic
- Solver: FE
- Simulation time: 4200000.000000
- dt: 0.002000
- Constants to change: 21
* GNa in INa: 98.567807
* GNaL_b in INaL: 0.005618
* Gto_b in Ito: 0.073610
* PCa_b in ICaL: 0.000081
* GKr_b in IKr: 0.034050
* GKs_b in IKs: 0.001875
* GK1_b in IK1: 0.144311
* Gncx_b in INaCa_i: 0.000960
* Pnak_b in INaK: 68.003345
* GKb_b in IKb: 0.003769
* PNab in INab: 0.000000
* PCab in ICab: 0.000000
* GpCa in IpCa: 0.047131
* celltype in environment: 0.000000
* nCL_1 in membrane: 1000.000000
* CL_1 in membrane: 600.000000
* nCL_2 in membrane: 600.000000
* CL_2 in membrane: 1000.000000
* cao in extracellular: 1.000000
* ko in extracellular: 4.000000
* nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
- Iteration number: 1471280681
Loading states...
- states[0]: -87.000000 (Before loading)
- states[40]: 0.000000 (Before loading)
- states[0]: -94.904782 (After loading)
- states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint...
Iteration: 1528556891, states[0] = 2.989491, states[40]= 0.005228
Saving checkpoint...
Iteration: 1591577337, states[0] = -16.636599, states[40]= 0.001427
Saving checkpoint...
Iteration: 1660249464, states[0] = 6.910337, states[40]= 0.005666
===============================================================
--- DENIS Myocyte Simulator ---
Version 0.22 - Beta
---------------------------------------------------------------
https://denis.usj.es
Universidad San Jorge
===============================================================
Boinc file names:
- INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626223132141174_ORdGradInc_k_24-Pueyo_APDR-conf_88.xml
- OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626223132141174_ORdGradInc_k_24-Pueyo_APDR-conf_88_1_r1352467757_0
- MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626223132141174_ORdGradInc_k_24-Pueyo_APDR-conf_88_1_r1352467757_1
- CHECKPOINT_FILE: denis_checkpoint
- CHECKPOINT_FILE_2: denis_checkpoint_2
Configuration:
- Model name: ORd_SS_biphasic
- Solver: FE
- Simulation time: 4200000.000000
- dt: 0.002000
- Constants to change: 21
* GNa in INa: 98.567807
* GNaL_b in INaL: 0.005618
* Gto_b in Ito: 0.073610
* PCa_b in ICaL: 0.000081
* GKr_b in IKr: 0.034050
* GKs_b in IKs: 0.001875
* GK1_b in IK1: 0.144311
* Gncx_b in INaCa_i: 0.000960
* Pnak_b in INaK: 68.003345
* GKb_b in IKb: 0.003769
* PNab in INab: 0.000000
* PCab in ICab: 0.000000
* GpCa in IpCa: 0.047131
* celltype in environment: 0.000000
* nCL_1 in membrane: 1000.000000
* CL_1 in membrane: 600.000000
* nCL_2 in membrane: 600.000000
* CL_2 in membrane: 1000.000000
* cao in extracellular: 1.000000
* ko in extracellular: 4.000000
* nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
- Iteration number: 1660249464
Loading states...
- states[0]: -87.000000 (Before loading)
- states[40]: 0.000000 (Before loading)
- states[0]: 6.910337 (After loading)
- states[40]: 0.005666 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading resultsTime...
Loading resultsAPD90...
Loading resultsAPD75...
Loading resultsAPD50...
Loading resultsAPD25...
Loading resultsAPD10...
Loading resultsTriangulation...
Loading resultsMaxV...
Loading resultsMinV...
Loading resultsMaxDiffV...
Loading resultsMinDiffV...
Copy resultsTime...
Copy resultsAPD90...
Copy resultsAPD75...
Copy resultsAPD50...
Copy resultsAPD25...
Copy resultsAPD10...
Copy resultsTriangulation...
Copy resultsMaxV...
Copy resultsMinV...
Copy resultsMaxDiffV...
Copy resultsMinDiffV...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
===============================================================
--- DENIS Myocyte Simulator ---
Version 0.22 - Beta
---------------------------------------------------------------
https://denis.usj.es
Universidad San Jorge
===============================================================
Boinc file names:
- INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626223132141174_ORdGradInc_k_24-Pueyo_APDR-conf_88.xml
- OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626223132141174_ORdGradInc_k_24-Pueyo_APDR-conf_88_1_r1352467757_0
- MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626223132141174_ORdGradInc_k_24-Pueyo_APDR-conf_88_1_r1352467757_1
- CHECKPOINT_FILE: denis_checkpoint
- CHECKPOINT_FILE_2: denis_checkpoint_2
Configuration:
- Model name: ORd_SS_biphasic
- Solver: FE
- Simulation time: 4200000.000000
- dt: 0.002000
- Constants to change: 21
* GNa in INa: 98.567807
* GNaL_b in INaL: 0.005618
* Gto_b in Ito: 0.073610
* PCa_b in ICaL: 0.000081
* GKr_b in IKr: 0.034050
* GKs_b in IKs: 0.001875
* GK1_b in IK1: 0.144311
* Gncx_b in INaCa_i: 0.000960
* Pnak_b in INaK: 68.003345
* GKb_b in IKb: 0.003769
* PNab in INab: 0.000000
* PCab in ICab: 0.000000
* GpCa in IpCa: 0.047131
* celltype in environment: 0.000000
* nCL_1 in membrane: 1000.000000
* CL_1 in membrane: 600.000000
* nCL_2 in membrane: 600.000000
* CL_2 in membrane: 1000.000000
* cao in extracellular: 1.000000
* ko in extracellular: 4.000000
* nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
- Iteration number: 1660249464
Loading states...
- states[0]: -87.000000 (Before loading)
- states[40]: 0.000000 (Before loading)
- states[0]: 6.910337 (After loading)
- states[40]: 0.005666 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading resultsTime...
Loading resultsAPD90...
Loading resultsAPD75...
Loading resultsAPD50...
Loading resultsAPD25...
Loading resultsAPD10...
Loading resultsTriangulation...
Loading resultsMaxV...
Loading resultsMinV...
Loading resultsMaxDiffV...
Loading resultsMinDiffV...
Copy resultsTime...
Copy resultsAPD90...
Copy resultsAPD75...
Copy resultsAPD50...
Copy resultsAPD25...
Copy resultsAPD10...
Copy resultsTriangulation...
Copy resultsMaxV...
Copy resultsMinV...
Copy resultsMaxDiffV...
Copy resultsMinDiffV...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
===============================================================
--- DENIS Myocyte Simulator ---
Version 0.22 - Beta
---------------------------------------------------------------
https://denis.usj.es
Universidad San Jorge
===============================================================
Boinc file names:
- INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626223132141174_ORdGradInc_k_24-Pueyo_APDR-conf_88.xml
- OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626223132141174_ORdGradInc_k_24-Pueyo_APDR-conf_88_1_r1352467757_0
- MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626223132141174_ORdGradInc_k_24-Pueyo_APDR-conf_88_1_r1352467757_1
- CHECKPOINT_FILE: denis_checkpoint
- CHECKPOINT_FILE_2: denis_checkpoint_2
Configuration:
- Model name: ORd_SS_biphasic
- Solver: FE
- Simulation time: 4200000.000000
- dt: 0.002000
- Constants to change: 21
* GNa in INa: 98.567807
* GNaL_b in INaL: 0.005618
* Gto_b in Ito: 0.073610
* PCa_b in ICaL: 0.000081
* GKr_b in IKr: 0.034050
* GKs_b in IKs: 0.001875
* GK1_b in IK1: 0.144311
* Gncx_b in INaCa_i: 0.000960
* Pnak_b in INaK: 68.003345
* GKb_b in IKb: 0.003769
* PNab in INab: 0.000000
* PCab in ICab: 0.000000
* GpCa in IpCa: 0.047131
* celltype in environment: 0.000000
* nCL_1 in membrane: 1000.000000
* CL_1 in membrane: 600.000000
* nCL_2 in membrane: 600.000000
* CL_2 in membrane: 1000.000000
* cao in extracellular: 1.000000
* ko in extracellular: 4.000000
* nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
- Iteration number: 1660249464
Loading states...
- states[0]: -87.000000 (Before loading)
- states[40]: 0.000000 (Before loading)
- states[0]: 6.910337 (After loading)
- states[40]: 0.005666 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading resultsTime...
Loading resultsAPD90...
Loading resultsAPD75...
Loading resultsAPD50...
Loading resultsAPD25...
Loading resultsAPD10...
Loading resultsTriangulation...
Loading resultsMaxV...
Loading resultsMinV...
Loading resultsMaxDiffV...
Loading resultsMinDiffV...
Copy resultsTime...
Copy resultsAPD90...
Copy resultsAPD75...
Copy resultsAPD50...
Copy resultsAPD25...
Copy resultsAPD10...
Copy resultsTriangulation...
Copy resultsMaxV...
Copy resultsMinV...
Copy resultsMaxDiffV...
Copy resultsMinDiffV...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint...
Iteration: 1723964512, states[0] = -95.116349, states[40]= 0.000000
Saving checkpoint...
Iteration: 1796197499, states[0] = -40.545327, states[40]= 0.000115
Saving checkpoint...
Iteration: 1877472905, states[0] = -94.995821, states[40]= 0.000000
===============================================================
--- DENIS Myocyte Simulator ---
Version 0.22 - Beta
---------------------------------------------------------------
https://denis.usj.es
Universidad San Jorge
===============================================================
Boinc file names:
- INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626223132141174_ORdGradInc_k_24-Pueyo_APDR-conf_88.xml
- OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626223132141174_ORdGradInc_k_24-Pueyo_APDR-conf_88_1_r1352467757_0
- MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626223132141174_ORdGradInc_k_24-Pueyo_APDR-conf_88_1_r1352467757_1
- CHECKPOINT_FILE: denis_checkpoint
- CHECKPOINT_FILE_2: denis_checkpoint_2
Configuration:
- Model name: ORd_SS_biphasic
- Solver: FE
- Simulation time: 4200000.000000
- dt: 0.002000
- Constants to change: 21
* GNa in INa: 98.567807
* GNaL_b in INaL: 0.005618
* Gto_b in Ito: 0.073610
* PCa_b in ICaL: 0.000081
* GKr_b in IKr: 0.034050
* GKs_b in IKs: 0.001875
* GK1_b in IK1: 0.144311
* Gncx_b in INaCa_i: 0.000960
* Pnak_b in INaK: 68.003345
* GKb_b in IKb: 0.003769
* PNab in INab: 0.000000
* PCab in ICab: 0.000000
* GpCa in IpCa: 0.047131
* celltype in environment: 0.000000
* nCL_1 in membrane: 1000.000000
* CL_1 in membrane: 600.000000
* nCL_2 in membrane: 600.000000
* CL_2 in membrane: 1000.000000
* cao in extracellular: 1.000000
* ko in extracellular: 4.000000
* nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
- Iteration number: 1877472905
Loading states...
- states[0]: -87.000000 (Before loading)
- states[40]: 0.000000 (Before loading)
- states[0]: -94.995821 (After loading)
- states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading resultsTime...
Loading resultsAPD90...
Loading resultsAPD75...
Loading resultsAPD50...
Loading resultsAPD25...
Loading resultsAPD10...
Loading resultsTriangulation...
Loading resultsMaxV...
Loading resultsMinV...
Loading resultsMaxDiffV...
Loading resultsMinDiffV...
Copy resultsTime...
Copy resultsAPD90...
Copy resultsAPD75...
Copy resultsAPD50...
Copy resultsAPD25...
Copy resultsAPD10...
Copy resultsTriangulation...
Copy resultsMaxV...
Copy resultsMinV...
Copy resultsMaxDiffV...
Copy resultsMinDiffV...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
===============================================================
--- DENIS Myocyte Simulator ---
Version 0.22 - Beta
---------------------------------------------------------------
https://denis.usj.es
Universidad San Jorge
===============================================================
Boinc file names:
- INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626223132141174_ORdGradInc_k_24-Pueyo_APDR-conf_88.xml
- OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626223132141174_ORdGradInc_k_24-Pueyo_APDR-conf_88_1_r1352467757_0
- MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626223132141174_ORdGradInc_k_24-Pueyo_APDR-conf_88_1_r1352467757_1
- CHECKPOINT_FILE: denis_checkpoint
- CHECKPOINT_FILE_2: denis_checkpoint_2
Configuration:
- Model name: ORd_SS_biphasic
- Solver: FE
- Simulation time: 4200000.000000
- dt: 0.002000
- Constants to change: 21
* GNa in INa: 98.567807
* GNaL_b in INaL: 0.005618
* Gto_b in Ito: 0.073610
* PCa_b in ICaL: 0.000081
* GKr_b in IKr: 0.034050
* GKs_b in IKs: 0.001875
* GK1_b in IK1: 0.144311
* Gncx_b in INaCa_i: 0.000960
* Pnak_b in INaK: 68.003345
* GKb_b in IKb: 0.003769
* PNab in INab: 0.000000
* PCab in ICab: 0.000000
* GpCa in IpCa: 0.047131
* celltype in environment: 0.000000
* nCL_1 in membrane: 1000.000000
* CL_1 in membrane: 600.000000
* nCL_2 in membrane: 600.000000
* CL_2 in membrane: 1000.000000
* cao in extracellular: 1.000000
* ko in extracellular: 4.000000
* nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
- Iteration number: 1877472905
Loading states...
- states[0]: -87.000000 (Before loading)
- states[40]: 0.000000 (Before loading)
- states[0]: -94.995821 (After loading)
- states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading resultsTime...
Loading resultsAPD90...
Loading resultsAPD75...
Loading resultsAPD50...
Loading resultsAPD25...
Loading resultsAPD10...
Loading resultsTriangulation...
Loading resultsMaxV...
Loading resultsMinV...
Loading resultsMaxDiffV...
Loading resultsMinDiffV...
Copy resultsTime...
Copy resultsAPD90...
Copy resultsAPD75...
Copy resultsAPD50...
Copy resultsAPD25...
Copy resultsAPD10...
Copy resultsTriangulation...
Copy resultsMaxV...
Copy resultsMinV...
Copy resultsMaxDiffV...
Copy resultsMinDiffV...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint...
Iteration: 1941702111, states[0] = -94.791836, states[40]= 0.000000
Saving checkpoint...
Iteration: 2015523794, states[0] = 20.722115, states[40]= 0.008049
Saving checkpoint...
Iteration: 2088940057, states[0] = -94.980778, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
- v in component membrane (millivolt): -94.865890
- CaMKt in component CaMK (millimolar): 0.006561
- cass in component intracellular_ions (millimolar): 0.000073
- nai in component intracellular_ions (millimolar): 6.585516
- nass in component intracellular_ions (millimolar): 6.585574
- ki in component intracellular_ions (millimolar): 145.397599
- kss in component intracellular_ions (millimolar): 145.397580
- cansr in component intracellular_ions (millimolar): 1.290229
- cajsr in component intracellular_ions (millimolar): 1.253334
- cai in component intracellular_ions (millimolar): 0.000074
- m in component INa (dimensionless): 0.003632
- hf in component INa (dimensionless): 0.879375
- hs in component INa (dimensionless): 0.879371
- j in component INa (dimensionless): 0.879342
- hsp in component INa (dimensionless): 0.724653
- jp in component INa (dimensionless): 0.879323
- mL in component INaL (dimensionless): 0.000050
- hL in component INaL (dimensionless): 0.710421
- hLp in component INaL (dimensionless): 0.455273
- a in component Ito (dimensionless): 0.000625
- iF in component Ito (dimensionless): 0.999869
- iS in component Ito (dimensionless): 0.627882
- ap in component Ito (dimensionless): 0.000318
- iFp in component Ito (dimensionless): 0.999869
- iSp in component Ito (dimensionless): 0.703619
- d in component ICaL (dimensionless): 0.000000
- ff in component ICaL (dimensionless): 1.000000
- fs in component ICaL (dimensionless): 0.937829
- fcaf in component ICaL (dimensionless): 1.000000
- fcas in component ICaL (dimensionless): 0.999898
- jca in component ICaL (dimensionless): 0.999981
- ffp in component ICaL (dimensionless): 1.000000
- fcafp in component ICaL (dimensionless): 1.000000
- nca in component ICaL (dimensionless): 0.001524
- xrf in component IKr (dimensionless): 0.000003
- xrs in component IKr (dimensionless): 0.328788
- xs1 in component IKs (dimensionless): 0.232490
- xs2 in component IKs (dimensionless): 0.000088
- xk1 in component IK1 (dimensionless): 0.997347
- Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
- Jrelp in component ryr (millimolar_per_millisecond): 0.000000
12:58:18 (23085): called boinc_finish(0)
</stderr_txt>
]]>
