𝕏

Task 54879822

Name HuVeMOp_20240626210043898283_ORdGradInc_k_24-Pueyo_APDR-conf_243_1
Workunit 26058412
Created 26 Jun 2024, 19:01:02 UTC
Sent 26 Jun 2024, 20:18:13 UTC
Report deadline 30 Jun 2024, 5:54:13 UTC
Received 27 Jun 2024, 1:01:38 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 232912
Run time 1 hours 51 min 45 sec
CPU time 1 hours 49 min 57 sec
Validate state Valid
Credit 61.33
Device peak FLOPS 5.34 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.98 MB
Peak swap size 32.60 GB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.24.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626210043898283_ORdGradInc_k_24-Pueyo_APDR-conf_243.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626210043898283_ORdGradInc_k_24-Pueyo_APDR-conf_243_1_r858663119_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626210043898283_ORdGradInc_k_24-Pueyo_APDR-conf_243_1_r858663119_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 121.473157
     * GNaL_b in INaL: 0.005397
     * Gto_b in Ito: 0.067165
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.032704
     * GKs_b in IKs: 0.001805
     * GK1_b in IK1: 0.159986
     * Gncx_b in INaCa_i: 0.000970
     * Pnak_b in INaK: 63.916287
     * GKb_b in IKb: 0.003899
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.041045
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 19400527, states[0] = -95.145024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 38907921, states[0] = -95.125438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58380620, states[0] = -95.106726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 77790505, states[0] = -95.054669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97131144, states[0] = -60.659043, states[40]= 0.000004
Saving checkpoint... 
Iteration: 116587270, states[0] = -13.315333, states[40]= 0.001796
Saving checkpoint... 
Iteration: 136132765, states[0] = -62.367852, states[40]= 0.000003
Saving checkpoint... 
Iteration: 155547527, states[0] = 11.479732, states[40]= 0.005463
Saving checkpoint... 
Iteration: 174991116, states[0] = -95.115070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 194399771, states[0] = -95.098181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 213911803, states[0] = -95.101108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 233278941, states[0] = -95.036841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 252761049, states[0] = -95.019849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 272138288, states[0] = -69.545388, states[40]= 0.000001
Saving checkpoint... 
Iteration: 291547272, states[0] = 11.608701, states[40]= 0.005474
Saving checkpoint... 
Iteration: 311017649, states[0] = 22.819869, states[40]= 0.014697
Saving checkpoint... 
Iteration: 330476901, states[0] = -95.112682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 349887914, states[0] = -95.094400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 369275068, states[0] = -95.033256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 388759524, states[0] = -95.018128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 408237505, states[0] = -94.992140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 427582647, states[0] = -8.800908, states[40]= 0.002700
Saving checkpoint... 
Iteration: 446965117, states[0] = -95.110973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 466448506, states[0] = -95.108314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 485938154, states[0] = -95.106435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 505268389, states[0] = -95.026985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 524675348, states[0] = -94.879721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 544126277, states[0] = -54.428548, states[40]= 0.000012
Saving checkpoint... 
Iteration: 563570533, states[0] = 0.108724, states[40]= 0.004467
Saving checkpoint... 
Iteration: 583109771, states[0] = -36.155852, states[40]= 0.000208
Saving checkpoint... 
Iteration: 602486632, states[0] = -95.113775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 621904163, states[0] = -95.098811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641352648, states[0] = -95.081672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 660705815, states[0] = -94.943048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 680107748, states[0] = -34.050252, states[40]= 0.000274
Saving checkpoint... 
Iteration: 699478851, states[0] = -95.112755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 718874040, states[0] = -95.089759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 738335756, states[0] = -95.073939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 757703429, states[0] = -94.938703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 777194798, states[0] = -94.922448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 796672102, states[0] = -94.867111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 816013149, states[0] = 24.278556, states[40]= 0.029121
Saving checkpoint... 
Iteration: 835416253, states[0] = -95.101674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 854861706, states[0] = -95.085212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 874337676, states[0] = -95.074812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 893799373, states[0] = -95.052355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 913232759, states[0] = -94.985495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 932584887, states[0] = -10.853893, states[40]= 0.002260
Saving checkpoint... 
Iteration: 952073135, states[0] = -1.516644, states[40]= 0.004215
Saving checkpoint... 
Iteration: 971524576, states[0] = 20.615645, states[40]= 0.008593
Saving checkpoint... 
Iteration: 991044024, states[0] = 13.018577, states[40]= 0.005622
Saving checkpoint... 
Iteration: 1010409338, states[0] = -95.099937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1029873302, states[0] = -95.089359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1049309448, states[0] = -95.059025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1068756374, states[0] = -95.014437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1088111004, states[0] = -37.448069, states[40]= 0.000174
Saving checkpoint... 
Iteration: 1107481094, states[0] = -95.112851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1126970509, states[0] = -95.111428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1146402930, states[0] = -95.098242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1165751128, states[0] = -95.008536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1185283825, states[0] = -95.040390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1204763617, states[0] = -95.021956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1224223888, states[0] = -94.972528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1243607493, states[0] = -33.785595, states[40]= 0.000283
Saving checkpoint... 
Iteration: 1262962284, states[0] = -95.110165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1282444938, states[0] = -95.107305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1301979930, states[0] = -95.112611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1321414519, states[0] = -95.101040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1340864605, states[0] = -95.086083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1360303321, states[0] = -95.054857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1379726447, states[0] = -94.976269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1399129217, states[0] = -57.893212, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1418548086, states[0] = 11.251799, states[40]= 0.005441
Saving checkpoint... 
Iteration: 1438048902, states[0] = 10.891621, states[40]= 0.005411
Saving checkpoint... 
Iteration: 1457527292, states[0] = 19.677098, states[40]= 0.007688
Saving checkpoint... 
Iteration: 1476871513, states[0] = -95.088525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1496385242, states[0] = -95.093039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1515673032, states[0] = -10.533048, states[40]= 0.002565
Saving checkpoint... 
Iteration: 1534959517, states[0] = -95.183656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1554193434, states[0] = -95.269760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1573387577, states[0] = -95.265098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1592547473, states[0] = -95.142332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1611776323, states[0] = -95.247414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1630978539, states[0] = -95.253314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1650256370, states[0] = -95.366672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1669531497, states[0] = 16.353373, states[40]= 0.007722
Saving checkpoint... 
Iteration: 1688953740, states[0] = -95.364719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1708071218, states[0] = -95.238249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1727393901, states[0] = -95.395742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1746733795, states[0] = -92.963605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1765990281, states[0] = -95.278260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1785310939, states[0] = 25.769121, states[40]= 0.045330
Saving checkpoint... 
Iteration: 1804479653, states[0] = -95.169034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1823647251, states[0] = -88.620817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1842914927, states[0] = -95.121719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1862097210, states[0] = -24.009963, states[40]= 0.000728
Saving checkpoint... 
Iteration: 1881325985, states[0] = -95.075472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1900426998, states[0] = -95.107692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1919680079, states[0] = -94.893924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1938965114, states[0] = -95.111670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1958050986, states[0] = 9.946722, states[40]= 0.005339
Saving checkpoint... 
Iteration: 1977364386, states[0] = -95.086162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1996558324, states[0] = 6.563499, states[40]= 0.005107
Saving checkpoint... 
Iteration: 2015874217, states[0] = -95.089342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2035105294, states[0] = -31.519449, states[40]= 0.000371
Saving checkpoint... 
Iteration: 2054305786, states[0] = -95.056198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2073538224, states[0] = 15.463197, states[40]= 0.006009
Saving checkpoint... 
Iteration: 2092770180, states[0] = -95.027921, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.990437
 - CaMKt in component CaMK (millimolar): 0.006408
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.688613
 - nass in component intracellular_ions (millimolar): 6.688672
 - ki in component intracellular_ions (millimolar): 145.295911
 - kss in component intracellular_ions (millimolar): 145.295891
 - cansr in component intracellular_ions (millimolar): 1.287548
 - cajsr in component intracellular_ions (millimolar): 1.251095
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003586
 - hf in component INa (dimensionless): 0.881529
 - hs in component INa (dimensionless): 0.881525
 - j in component INa (dimensionless): 0.881499
 - hsp in component INa (dimensionless): 0.728720
 - jp in component INa (dimensionless): 0.881482
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.714376
 - hLp in component INaL (dimensionless): 0.461193
 - a in component Ito (dimensionless): 0.000620
 - iF in component Ito (dimensionless): 0.999872
 - iS in component Ito (dimensionless): 0.630979
 - ap in component Ito (dimensionless): 0.000316
 - iFp in component Ito (dimensionless): 0.999872
 - iSp in component Ito (dimensionless): 0.707327
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.938506
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999898
 - jca in component ICaL (dimensionless): 0.999982
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001528
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.337959
 - xs1 in component IKs (dimensionless): 0.229043
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997314
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
02:38:36 (39368): called boinc_finish(0)

</stderr_txt>
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