𝕏

Task 54878240

Name HuVeMOp_20240626203708416222_ORdGradInc_k_24-Drouin_ENDO_6000-conf_272_0
Workunit 26057643
Created 26 Jun 2024, 18:38:02 UTC
Sent 26 Jun 2024, 20:02:26 UTC
Report deadline 29 Jun 2024, 20:02:26 UTC
Received 28 Jun 2024, 4:16:44 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 239842
Run time 1 hours 3 min 18 sec
CPU time 53 min 59 sec
Validate state Valid
Credit 40.67
Device peak FLOPS 6.87 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.47 MB
Peak swap size 3.69 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.20.5</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626203708416222_ORdGradInc_k_24-Drouin_ENDO_6000-conf_272.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626203708416222_ORdGradInc_k_24-Drouin_ENDO_6000-conf_272_0_r709189195_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626203708416222_ORdGradInc_k_24-Drouin_ENDO_6000-conf_272_0_r709189195_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 121.571002
     * GNaL_b in INaL: 0.007827
     * Gto_b in Ito: 0.087262
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.032549
     * GKs_b in IKs: 0.001787
     * GK1_b in IK1: 0.173117
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 69.216074
     * GKb_b in IKb: 0.003856
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.053232
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 500.000000
     * CL_0 in membrane: 6000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 8683633, states[0] = -94.361708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 16926307, states[0] = -94.291065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24994660, states[0] = -94.268318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33426217, states[0] = -94.169037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 41216631, states[0] = -94.208277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 49940182, states[0] = -94.203118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58425044, states[0] = -94.207949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 66416193, states[0] = -94.130044, states[40]= 0.000000
Saving checkpoint... 
Iteration: 74748002, states[0] = -94.186052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 83412898, states[0] = -94.187169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 91172876, states[0] = -94.208267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 99942156, states[0] = -94.214909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 108454021, states[0] = -94.154459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 116494736, states[0] = -94.183942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 124969767, states[0] = -94.189098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133752704, states[0] = -94.192128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 141920214, states[0] = -94.213812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 150367496, states[0] = -94.064476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 158829564, states[0] = -94.180513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 166977903, states[0] = -94.188092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 175704835, states[0] = -94.192249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 184429164, states[0] = -94.198005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 192740937, states[0] = -94.215050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 201175228, states[0] = -46.418455, states[40]= 0.000487
Saving checkpoint... 
Iteration: 209895195, states[0] = -94.179683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 218246083, states[0] = -94.184579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226860557, states[0] = -94.189353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 235796501, states[0] = -94.190331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 244220039, states[0] = -94.203474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 252521304, states[0] = -94.185174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 261328097, states[0] = -93.990838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 269492984, states[0] = -94.182193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 278170226, states[0] = -94.185209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 287043797, states[0] = -94.186673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 295133579, states[0] = -94.206075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 304065852, states[0] = -94.208267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 312683653, states[0] = -94.212621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 320986021, states[0] = -94.178908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 329790019, states[0] = -94.180000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 338464240, states[0] = -94.182305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346528910, states[0] = -94.195192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 355284777, states[0] = -94.201351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 364015958, states[0] = -94.209801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 372192517, states[0] = -61.045087, states[40]= 0.000050
Saving checkpoint... 
Iteration: 380961389, states[0] = -94.178946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 389669142, states[0] = -94.180692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 397898546, states[0] = -94.188460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 406710813, states[0] = -94.191485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 415512167, states[0] = -94.195463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 423385558, states[0] = -94.088449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432099481, states[0] = 6.444646, states[40]= 0.004165
Saving checkpoint... 
Iteration: 440852095, states[0] = -94.179466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 448971530, states[0] = -94.187364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 457809624, states[0] = -94.189735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 466580062, states[0] = -94.193924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474362041, states[0] = -94.054880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 482891383, states[0] = -94.179182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 491615985, states[0] = -94.180918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 499693257, states[0] = -94.191670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 508507217, states[0] = -94.195443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 517263755, states[0] = -94.201728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 525263395, states[0] = -93.788338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 533488410, states[0] = -94.181828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 542108404, states[0] = -94.185513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 550246788, states[0] = -94.202182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 558801424, states[0] = -94.214644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 567435734, states[0] = -94.138685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 575859526, states[0] = -94.179232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 584268123, states[0] = -94.183729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 593019653, states[0] = -94.186527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 601342503, states[0] = -94.199391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 609909478, states[0] = -94.212648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 618623126, states[0] = -94.206930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 626706540, states[0] = -94.180104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 635475961, states[0] = -94.181784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 644612353, states[0] = -94.180728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 652744609, states[0] = -94.190542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 661264238, states[0] = -94.201510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 669891805, states[0] = -94.213011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 678194009, states[0] = -62.410853, states[40]= 0.000040
Saving checkpoint... 
Iteration: 686939080, states[0] = -94.178630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 695495864, states[0] = -94.181538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 703542798, states[0] = -94.194380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 712072307, states[0] = -94.207467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 720734729, states[0] = -94.213971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 729176813, states[0] = -47.693884, states[40]= 0.000407
Saving checkpoint... 
Iteration: 737855070, states[0] = -94.179028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 746551474, states[0] = -94.181033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 754572164, states[0] = -94.193682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763147532, states[0] = -94.204951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 771508580, states[0] = -94.179680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 779587442, states[0] = -94.180717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 788199850, states[0] = -94.184144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 797213417, states[0] = -94.183987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 806128672, states[0] = -94.184904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 815349804, states[0] = -94.182621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 823642422, states[0] = -94.192168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 832142786, states[0] = -94.205005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 840911268, states[0] = -94.212275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 849084017, states[0] = 13.378119, states[40]= 0.002759
Saving checkpoint... 
Iteration: 857107942, states[0] = -94.185072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 865789379, states[0] = -94.189487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 873666941, states[0] = -94.210753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 881477381, states[0] = -94.181424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 889914547, states[0] = -94.187531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 898065321, states[0] = -94.207434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 906508322, states[0] = -94.179388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 915039369, states[0] = 28.707947, states[40]= 0.000332
Saving checkpoint... 
Iteration: 923391079, states[0] = -94.182096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 931534880, states[0] = -94.194230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 939868849, states[0] = -94.213150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 947934797, states[0] = -94.178284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 956053593, states[0] = -94.185586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 964462733, states[0] = -94.195827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 972714806, states[0] = -94.213068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 981075374, states[0] = 16.819450, states[40]= 0.001984
Saving checkpoint... 
Iteration: 989687701, states[0] = -94.179716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 997896653, states[0] = -94.187638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1006141941, states[0] = -94.204787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1014526836, states[0] = -94.185930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1022841316, states[0] = -94.178705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1030955626, states[0] = -94.186756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1039509944, states[0] = -94.194630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1047913583, states[0] = -94.211921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1055933163, states[0] = -94.178140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1064514520, states[0] = -94.180868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1072917087, states[0] = -94.187236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1080811090, states[0] = -94.213838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1089107778, states[0] = 2.139289, states[40]= 0.004594
Saving checkpoint... 
Iteration: 1097403585, states[0] = -94.181740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1105516562, states[0] = -94.194389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1113845712, states[0] = -94.213344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1122091132, states[0] = 10.331546, states[40]= 0.003440
Saving checkpoint... 
Iteration: 1130119436, states[0] = -94.184552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1138570110, states[0] = -94.193182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1147031956, states[0] = -94.208174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1154860822, states[0] = -94.178405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1163466780, states[0] = -94.181112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1171722047, states[0] = -94.190202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1180200984, states[0] = -94.202680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1188433860, states[0] = -94.136323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1196489916, states[0] = -94.180877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1204643556, states[0] = -94.191608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1213008124, states[0] = -94.208852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1221031774, states[0] = 30.471643, states[40]= 0.000255
Saving checkpoint... 
Iteration: 1229263045, states[0] = -94.182867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1237655963, states[0] = -94.191323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1245537359, states[0] = -94.188910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253592574, states[0] = -94.180009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1262065979, states[0] = -94.185001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1269711665, states[0] = -94.212540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1278026784, states[0] = 31.333250, states[40]= 0.000352
Saving checkpoint... 
Iteration: 1286760671, states[0] = -94.178821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1294764671, states[0] = -94.189291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1303279041, states[0] = -94.200173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1311554541, states[0] = -94.193536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1319292748, states[0] = -94.182447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1327469088, states[0] = -94.195164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336188218, states[0] = -94.202855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1344399569, states[0] = -94.103744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1352578177, states[0] = -94.179975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1361042815, states[0] = -94.185147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1368963362, states[0] = -94.210037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1377578724, states[0] = -94.198857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1386010960, states[0] = 30.975962, states[40]= 0.042467
Saving checkpoint... 
Iteration: 1394066305, states[0] = -94.184810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1402679768, states[0] = -94.190642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1411251466, states[0] = -94.200826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1419474370, states[0] = -94.162854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1427739366, states[0] = -94.178757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1436174175, states[0] = -94.183504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1444126227, states[0] = -94.204674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1452629044, states[0] = -94.206454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1460848830, states[0] = -94.178041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1468861994, states[0] = -94.187487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1476882430, states[0] = -94.212093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1485312420, states[0] = -93.951064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493383735, states[0] = -94.181355, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.053138
 - CaMKt in component CaMK (millimolar): 0.001328
 - cass in component intracellular_ions (millimolar): 0.000102
 - nai in component intracellular_ions (millimolar): 6.617272
 - nass in component intracellular_ions (millimolar): 6.617399
 - ki in component intracellular_ions (millimolar): 145.246986
 - kss in component intracellular_ions (millimolar): 145.246976
 - cansr in component intracellular_ions (millimolar): 1.839653
 - cajsr in component intracellular_ions (millimolar): 1.839473
 - cai in component intracellular_ions (millimolar): 0.000106
 - m in component INa (dimensionless): 0.003942
 - hf in component INa (dimensionless): 0.864475
 - hs in component INa (dimensionless): 0.864475
 - j in component INa (dimensionless): 0.864477
 - hsp in component INa (dimensionless): 0.697251
 - jp in component INa (dimensionless): 0.864477
 - mL in component INaL (dimensionless): 0.000058
 - hL in component INaL (dimensionless): 0.706221
 - hLp in component INaL (dimensionless): 0.512301
 - a in component Ito (dimensionless): 0.000660
 - iF in component Ito (dimensionless): 0.999849
 - iS in component Ito (dimensionless): 0.999248
 - ap in component Ito (dimensionless): 0.000336
 - iFp in component Ito (dimensionless): 0.999849
 - iSp in component Ito (dimensionless): 0.999712
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.999502
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005563
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.000547
 - xs1 in component IKs (dimensionless): 0.015082
 - xs2 in component IKs (dimensionless): 0.000097
 - xk1 in component IK1 (dimensionless): 0.997551
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
23:16:36 (3100435): called boinc_finish(0)

</stderr_txt>
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