𝕏

Task 54876257

Name HuVeMOp_20240626203548235982_ORdGradInc_k_24-Pueyo_APDR-conf_278_1
Workunit 26056651
Created 26 Jun 2024, 18:36:49 UTC
Sent 26 Jun 2024, 19:45:38 UTC
Report deadline 30 Jun 2024, 5:21:38 UTC
Received 26 Jun 2024, 23:03:09 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241023
Run time 2 hours 28 min 57 sec
CPU time 2 hours 26 min 45 sec
Validate state Initial
Credit 0.00
Device peak FLOPS 1.00 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.25 MB
Peak swap size 3.82 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626203548235982_ORdGradInc_k_24-Pueyo_APDR-conf_278.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626203548235982_ORdGradInc_k_24-Pueyo_APDR-conf_278_1_r1812632934_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626203548235982_ORdGradInc_k_24-Pueyo_APDR-conf_278_1_r1812632934_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 117.379899
     * GNaL_b in INaL: 0.007775
     * Gto_b in Ito: 0.073108
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.032118
     * GKs_b in IKs: 0.001809
     * GK1_b in IK1: 0.166848
     * Gncx_b in INaCa_i: 0.000961
     * Pnak_b in INaK: 67.412136
     * GKb_b in IKb: 0.003974
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033034
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13967096, states[0] = -95.195484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 27873968, states[0] = -95.148558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 41941750, states[0] = -95.152279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 56558957, states[0] = 8.529859, states[40]= 0.005064
Saving checkpoint... 
Iteration: 71554227, states[0] = 10.620207, states[40]= 0.005153
Saving checkpoint... 
Iteration: 86327203, states[0] = -95.094868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 101304543, states[0] = -95.078287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 116381678, states[0] = -95.114669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 131362366, states[0] = -95.106614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 145797660, states[0] = -95.070106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 160016567, states[0] = 23.419811, states[40]= 0.015982
Saving checkpoint... 
Iteration: 174045463, states[0] = 14.273359, states[40]= 0.005366
Saving checkpoint... 
Iteration: 187971052, states[0] = -95.132425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 201883260, states[0] = -95.112564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 216049668, states[0] = 12.643777, states[40]= 0.005244
Saving checkpoint... 
Iteration: 230001687, states[0] = 49.822551, states[40]= 0.059847
Saving checkpoint... 
Iteration: 244022784, states[0] = 21.913396, states[40]= 0.008869
Saving checkpoint... 
Iteration: 258016739, states[0] = 23.387548, states[40]= 0.015613
Saving checkpoint... 
Iteration: 271843049, states[0] = -95.096262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 285801809, states[0] = -95.071879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 299683485, states[0] = -94.908505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 313594645, states[0] = -12.447449, states[40]= 0.001886
Saving checkpoint... 
Iteration: 327547046, states[0] = 13.671115, states[40]= 0.005315
Saving checkpoint... 
Iteration: 341963106, states[0] = -95.130787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 356838456, states[0] = -95.093932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 371783365, states[0] = -95.057257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 386599318, states[0] = -16.687793, states[40]= 0.001276
Saving checkpoint... 
Iteration: 401412915, states[0] = -95.120732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 416543622, states[0] = 14.986621, states[40]= 0.005437
Saving checkpoint... 
Iteration: 431882633, states[0] = -95.111995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 447299364, states[0] = -95.069993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 462849724, states[0] = -95.099235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 477941791, states[0] = -95.127014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 493115078, states[0] = -31.309253, states[40]= 0.000425
Saving checkpoint... 
Iteration: 508221937, states[0] = -94.983609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 523529521, states[0] = 19.957003, states[40]= 0.006759
Saving checkpoint... 
Iteration: 538482323, states[0] = -95.133441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 553908968, states[0] = -95.119648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 569062031, states[0] = 7.570068, states[40]= 0.004997
Saving checkpoint... 
Iteration: 584555682, states[0] = 10.237217, states[40]= 0.005121
Saving checkpoint... 
Iteration: 600080222, states[0] = -1.564308, states[40]= 0.004090
Saving checkpoint... 
Iteration: 615402467, states[0] = -95.117882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 630828639, states[0] = -95.088615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 646311306, states[0] = -95.078181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 661803985, states[0] = -95.073206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 677411535, states[0] = -95.120240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 692822879, states[0] = -95.085312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 708288917, states[0] = -95.061747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 723552296, states[0] = 11.605138, states[40]= 0.005186
Saving checkpoint... 
Iteration: 738754042, states[0] = -95.027532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 753988068, states[0] = -95.134061, states[40]= 0.000000
Saving checkpoint... 
Iteration: 768961007, states[0] = -95.130227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 783839699, states[0] = -95.094325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 799053026, states[0] = 11.312849, states[40]= 0.005171
Saving checkpoint... 
Iteration: 814093879, states[0] = -11.770343, states[40]= 0.002009
Saving checkpoint... 
Iteration: 828828255, states[0] = -95.088298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 844041445, states[0] = 15.806720, states[40]= 0.005539
Saving checkpoint... 
Iteration: 859424043, states[0] = -95.123129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 874801127, states[0] = -95.071055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 889811152, states[0] = -95.077952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 904602169, states[0] = -19.319835, states[40]= 0.001039
Saving checkpoint... 
Iteration: 919440993, states[0] = -95.126630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 934477874, states[0] = -95.132637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 948767215, states[0] = -95.041780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 963034157, states[0] = 18.427596, states[40]= 0.006102
Saving checkpoint... 
Iteration: 977291720, states[0] = -95.063865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 991300192, states[0] = -95.070314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1005125829, states[0] = -41.803640, states[40]= 0.000104
Saving checkpoint... 
Iteration: 1019014749, states[0] = 23.850246, states[40]= 0.021138
Saving checkpoint... 
Iteration: 1032840807, states[0] = -95.094741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1047123792, states[0] = -39.731781, states[40]= 0.000140
Saving checkpoint... 
Iteration: 1061346812, states[0] = -95.097590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1075948481, states[0] = -95.127940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1090658870, states[0] = -86.099003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1105442378, states[0] = -95.126797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1119705982, states[0] = -94.956068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1134823965, states[0] = -95.085710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1149750023, states[0] = -95.022538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1164857872, states[0] = -95.102400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1179733401, states[0] = -95.000586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1194021141, states[0] = 22.338350, states[40]= 0.009902
Saving checkpoint... 
Iteration: 1208695014, states[0] = -94.935346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1223465174, states[0] = -95.130642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1238753889, states[0] = -95.027090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1254164514, states[0] = -92.717630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1268690733, states[0] = -94.926652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1283732983, states[0] = -94.999932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1298207810, states[0] = -94.959268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1312565382, states[0] = 6.090214, states[40]= 0.004914
Saving checkpoint... 
Iteration: 1326962410, states[0] = -95.130157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1341260238, states[0] = -95.034208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1355265411, states[0] = -95.039711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1370070012, states[0] = 3.931668, states[40]= 0.004759
Saving checkpoint... 
Iteration: 1385417350, states[0] = -95.121299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1400757785, states[0] = -95.031461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415896810, states[0] = -95.115866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1431112969, states[0] = -29.330898, states[40]= 0.000522
Saving checkpoint... 
Iteration: 1446448342, states[0] = -95.127721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1461945704, states[0] = -95.127233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1476717625, states[0] = -94.976093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1491166703, states[0] = -93.765666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1505347472, states[0] = -95.312186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1519330171, states[0] = -71.086357, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1534285699, states[0] = -18.880400, states[40]= 0.001166
Saving checkpoint... 
Iteration: 1548422456, states[0] = -61.823879, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1562863203, states[0] = -95.208357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1577269375, states[0] = -95.228803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1591647458, states[0] = -94.849396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1606484762, states[0] = -95.393965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1621028750, states[0] = -72.786528, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1635236045, states[0] = -95.350513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1649417599, states[0] = 22.885814, states[40]= 0.015518
Saving checkpoint... 
Iteration: 1663594217, states[0] = -29.256059, states[40]= 0.000512
Saving checkpoint... 
Iteration: 1677670706, states[0] = -5.242715, states[40]= 0.003822
Saving checkpoint... 
Iteration: 1692041392, states[0] = 12.677995, states[40]= 0.006328
Saving checkpoint... 
Iteration: 1706224057, states[0] = -65.509191, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1719882017, states[0] = -95.394343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1733495792, states[0] = -30.955065, states[40]= 0.000431
Saving checkpoint... 
Iteration: 1747189323, states[0] = -95.399446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1760881086, states[0] = -95.261846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1774454859, states[0] = -95.371592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1788082506, states[0] = -16.831774, states[40]= 0.001406
Saving checkpoint... 
Iteration: 1801653447, states[0] = -86.227670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1815347811, states[0] = -95.139236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1828984786, states[0] = -95.161968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1842987894, states[0] = -95.152760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1856989848, states[0] = -95.146524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1870964448, states[0] = -95.138715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1886105761, states[0] = -22.995515, states[40]= 0.000828
Saving checkpoint... 
Iteration: 1901114331, states[0] = -30.848639, states[40]= 0.000446
Saving checkpoint... 
Iteration: 1916162332, states[0] = -91.108857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1931242757, states[0] = -95.014470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1946154431, states[0] = -78.276023, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1961138528, states[0] = -55.955599, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1976267865, states[0] = -95.042271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1991179394, states[0] = -94.886231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2005722481, states[0] = -94.983819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2020244472, states[0] = -95.015227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2034777643, states[0] = -95.051319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2049220998, states[0] = -94.981299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2063977006, states[0] = -95.131914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2077993825, states[0] = -95.134040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2092569739, states[0] = 4.063071, states[40]= 0.004769
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -95.010600
 - CaMKt in component CaMK (millimolar): 0.006793
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.636979
 - nass in component intracellular_ions (millimolar): 6.637039
 - ki in component intracellular_ions (millimolar): 145.343612
 - kss in component intracellular_ions (millimolar): 145.343592
 - cansr in component intracellular_ions (millimolar): 1.303571
 - cajsr in component intracellular_ions (millimolar): 1.265674
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003579
 - hf in component INa (dimensionless): 0.881875
 - hs in component INa (dimensionless): 0.881871
 - j in component INa (dimensionless): 0.881843
 - hsp in component INa (dimensionless): 0.729373
 - jp in component INa (dimensionless): 0.881825
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.712503
 - hLp in component INaL (dimensionless): 0.454433
 - a in component Ito (dimensionless): 0.000619
 - iF in component Ito (dimensionless): 0.999872
 - iS in component Ito (dimensionless): 0.619827
 - ap in component Ito (dimensionless): 0.000315
 - iFp in component Ito (dimensionless): 0.999872
 - iSp in component Ito (dimensionless): 0.694062
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.930995
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999871
 - jca in component ICaL (dimensionless): 0.999976
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001586
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.346712
 - xs1 in component IKs (dimensionless): 0.247543
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997308
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
00:15:18 (535809): called boinc_finish(0)

</stderr_txt>
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