𝕏

Task 54875385

Name HuVeMOp_20240626203548235982_ORdGradInc_k_24-Pueyo_APDR-conf_461_0
Workunit 26056216
Created 26 Jun 2024, 18:36:22 UTC
Sent 26 Jun 2024, 19:34:12 UTC
Report deadline 30 Jun 2024, 5:10:12 UTC
Received 28 Jun 2024, 18:41:27 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 214017
Run time 2 hours 45 min 33 sec
CPU time 2 hours 45 min 31 sec
Validate state Valid
Credit 54.85
Device peak FLOPS 3.52 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.80 MB
Peak swap size 3.82 MB
Peak disk usage 0.30 MB

Stderr output

<core_client_version>7.14.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626203548235982_ORdGradInc_k_24-Pueyo_APDR-conf_461.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626203548235982_ORdGradInc_k_24-Pueyo_APDR-conf_461_0_r1511060765_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626203548235982_ORdGradInc_k_24-Pueyo_APDR-conf_461_0_r1511060765_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 109.714675
     * GNaL_b in INaL: 0.005883
     * Gto_b in Ito: 0.085921
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033235
     * GKs_b in IKs: 0.001785
     * GK1_b in IK1: 0.156513
     * Gncx_b in INaCa_i: 0.000960
     * Pnak_b in INaK: 68.694165
     * GKb_b in IKb: 0.003805
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.049957
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13236684, states[0] = -94.928508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 26424276, states[0] = -95.013976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 39699809, states[0] = -94.815801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 52989216, states[0] = -94.997947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 66238875, states[0] = -94.863854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 79500461, states[0] = -34.713347, states[40]= 0.000004
Saving checkpoint... 
Iteration: 92804677, states[0] = -94.922912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 106107278, states[0] = -29.581947, states[40]= 0.000463
Saving checkpoint... 
Iteration: 119339556, states[0] = -94.940420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 132531827, states[0] = 17.524807, states[40]= 0.005920
Saving checkpoint... 
Iteration: 145751783, states[0] = -94.868004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 158934431, states[0] = -94.969682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 172136484, states[0] = -60.290873, states[40]= 0.000005
Saving checkpoint... 
Iteration: 185438123, states[0] = -94.969917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 198728363, states[0] = -94.834515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 211996632, states[0] = -94.978448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 225245901, states[0] = -94.859314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 238434432, states[0] = -94.968823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 250862788, states[0] = -94.947978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 264113624, states[0] = -35.601303, states[40]= 0.000228
Saving checkpoint... 
Iteration: 277402411, states[0] = -94.961153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 290629087, states[0] = -51.877696, states[40]= 0.000019
Saving checkpoint... 
Iteration: 303882080, states[0] = -94.954961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 317167641, states[0] = -94.442920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 330457357, states[0] = -94.972861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 343764116, states[0] = -94.880722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 357069506, states[0] = 2.108574, states[40]= 0.004496
Saving checkpoint... 
Iteration: 370363792, states[0] = -94.948246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 383658394, states[0] = -90.969154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396949841, states[0] = -94.971545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 410253018, states[0] = -94.867999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 423547083, states[0] = 12.004202, states[40]= 0.005040
Saving checkpoint... 
Iteration: 436840051, states[0] = -94.937598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 450135549, states[0] = -59.161245, states[40]= 0.000006
Saving checkpoint... 
Iteration: 463430725, states[0] = -94.967832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 476723723, states[0] = -94.826693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 490024586, states[0] = 19.668249, states[40]= 0.007365
Saving checkpoint... 
Iteration: 503336124, states[0] = -94.935554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 516632451, states[0] = -55.633857, states[40]= 0.000010
Saving checkpoint... 
Iteration: 529882440, states[0] = -94.954929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 543138787, states[0] = -62.969931, states[40]= 0.000003
Saving checkpoint... 
Iteration: 556388561, states[0] = -94.956888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 569623323, states[0] = -45.585506, states[40]= 0.000053
Saving checkpoint... 
Iteration: 582900257, states[0] = -94.960340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 596202823, states[0] = -94.789391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 609488129, states[0] = -94.977027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 622735994, states[0] = -94.845374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 635962896, states[0] = -94.973548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 648959606, states[0] = -94.973023, states[40]= 0.000000
Saving checkpoint... 
Iteration: 662229526, states[0] = -94.835737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 675449258, states[0] = -94.971272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 688737470, states[0] = -94.847442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 701945942, states[0] = -94.970662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 715194576, states[0] = -94.772898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 728481706, states[0] = -94.976151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 741756882, states[0] = -94.872375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 754971456, states[0] = -94.974746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 768200063, states[0] = -94.783894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 781433437, states[0] = -94.968200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 794681204, states[0] = -94.740667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 807969126, states[0] = -94.974378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 821210731, states[0] = -94.804108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 834447246, states[0] = -94.970817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 847734285, states[0] = -94.842756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861030929, states[0] = 17.834459, states[40]= 0.006033
Saving checkpoint... 
Iteration: 874064144, states[0] = 4.765159, states[40]= 0.004708
Saving checkpoint... 
Iteration: 887327613, states[0] = -94.930702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 900579353, states[0] = -3.802779, states[40]= 0.003637
Saving checkpoint... 
Iteration: 913075710, states[0] = -1.410500, states[40]= 0.004053
Saving checkpoint... 
Iteration: 926350228, states[0] = -94.942146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 939640664, states[0] = -65.270307, states[40]= 0.000002
Saving checkpoint... 
Iteration: 952907045, states[0] = -94.961957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 966187186, states[0] = -94.756881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 979440364, states[0] = -94.969451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 992713318, states[0] = -94.808663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1005990724, states[0] = -94.977095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1019280421, states[0] = -94.896479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1032569662, states[0] = 2.027038, states[40]= 0.004488
Saving checkpoint... 
Iteration: 1045866517, states[0] = -94.948899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1059162165, states[0] = -93.341663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1072271787, states[0] = -94.888220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1085519898, states[0] = 20.770228, states[40]= 0.010006
Saving checkpoint... 
Iteration: 1098751919, states[0] = -94.866239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1111986695, states[0] = -94.976545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1125243377, states[0] = -94.855302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1138493048, states[0] = -94.977285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1151741204, states[0] = -94.852352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1164989210, states[0] = -94.976818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1178256527, states[0] = -94.871694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1191551194, states[0] = 10.369526, states[40]= 0.004960
Saving checkpoint... 
Iteration: 1204828318, states[0] = -94.930905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1218083150, states[0] = -6.628524, states[40]= 0.003059
Saving checkpoint... 
Iteration: 1231371200, states[0] = -94.950558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1244661594, states[0] = -93.103249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1257959962, states[0] = -94.972708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1271238882, states[0] = -94.849071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1284513206, states[0] = 22.021019, states[40]= 0.026499
Saving checkpoint... 
Iteration: 1297792555, states[0] = -94.906701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1311077240, states[0] = -2.380338, states[40]= 0.003895
Saving checkpoint... 
Iteration: 1324367215, states[0] = -94.948998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1337660758, states[0] = -92.686499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1350931465, states[0] = -94.967444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1363782638, states[0] = -94.898264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1377060276, states[0] = 6.533543, states[40]= 0.004805
Saving checkpoint... 
Iteration: 1390334866, states[0] = -94.934353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1403636782, states[0] = -60.591778, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1416938539, states[0] = -94.968831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1430227121, states[0] = -94.831531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1443469822, states[0] = -94.974091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1456766500, states[0] = -94.882573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1470059340, states[0] = 6.947077, states[40]= 0.004824
Saving checkpoint... 
Iteration: 1483333663, states[0] = -94.933658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1496620663, states[0] = -42.767497, states[40]= 0.000082
Saving checkpoint... 
Iteration: 1509878350, states[0] = -95.208544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1523079103, states[0] = -95.225109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1536324569, states[0] = 18.998445, states[40]= 0.008564
Saving checkpoint... 
Iteration: 1549555342, states[0] = 3.757089, states[40]= 0.005246
Saving checkpoint... 
Iteration: 1562738558, states[0] = 12.744703, states[40]= 0.006183
Saving checkpoint... 
Iteration: 1575963677, states[0] = -2.138412, states[40]= 0.004418
Saving checkpoint... 
Iteration: 1589196438, states[0] = -36.958700, states[40]= 0.000192
Saving checkpoint... 
Iteration: 1602389271, states[0] = -28.964991, states[40]= 0.000488
Saving checkpoint... 
Iteration: 1615564538, states[0] = -2.966153, states[40]= 0.004260
Saving checkpoint... 
Iteration: 1628783920, states[0] = -23.036630, states[40]= 0.000809
Saving checkpoint... 
Iteration: 1642039033, states[0] = -93.524514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1652226435, states[0] = -76.600812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1660961928, states[0] = -95.080804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1669696003, states[0] = -95.159385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1678430588, states[0] = -95.214168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1690908410, states[0] = -51.492889, states[40]= 0.000022
Saving checkpoint... 
Iteration: 1703785368, states[0] = -24.723866, states[40]= 0.000707
Saving checkpoint... 
Iteration: 1716615941, states[0] = 21.594450, states[40]= 0.017844
Saving checkpoint... 
Iteration: 1729389923, states[0] = -95.147679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1742113936, states[0] = 22.180330, states[40]= 0.024613
Saving checkpoint... 
Iteration: 1752881908, states[0] = -95.265053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1762629171, states[0] = -81.516585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1772374369, states[0] = -95.259261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1782129617, states[0] = -82.320139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1791867827, states[0] = -95.253833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1803704606, states[0] = -94.847525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1816472839, states[0] = -95.020559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1829408468, states[0] = -94.994012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1839719790, states[0] = -94.843665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1848429880, states[0] = -94.985244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1857144795, states[0] = -72.068990, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1865851971, states[0] = -94.953375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1877444598, states[0] = -94.977490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1890310034, states[0] = -94.924578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1903017632, states[0] = 21.192361, states[40]= 0.012767
Saving checkpoint... 
Iteration: 1915840057, states[0] = -94.939191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1928698605, states[0] = -94.782017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1939139542, states[0] = -63.985802, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1950741225, states[0] = -94.852770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1963434317, states[0] = -94.968234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1976184851, states[0] = -94.751021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1985939960, states[0] = -94.969032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1995708208, states[0] = -94.798941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2005457139, states[0] = -94.971928, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2015197142, states[0] = -94.777396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2024930873, states[0] = -94.966960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2036597078, states[0] = -19.398092, states[40]= 0.000999
Saving checkpoint... 
Iteration: 2049470298, states[0] = -94.973787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2062368196, states[0] = -94.948904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2075251659, states[0] = -94.865292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2086463095, states[0] = -94.972657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2096182940, states[0] = -94.745326, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.853308
 - CaMKt in component CaMK (millimolar): 0.006816
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.639448
 - nass in component intracellular_ions (millimolar): 6.639507
 - ki in component intracellular_ions (millimolar): 145.340140
 - kss in component intracellular_ions (millimolar): 145.340120
 - cansr in component intracellular_ions (millimolar): 1.303846
 - cajsr in component intracellular_ions (millimolar): 1.266383
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003636
 - hf in component INa (dimensionless): 0.879156
 - hs in component INa (dimensionless): 0.879152
 - j in component INa (dimensionless): 0.879124
 - hsp in component INa (dimensionless): 0.724242
 - jp in component INa (dimensionless): 0.879106
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709505
 - hLp in component INaL (dimensionless): 0.453125
 - a in component Ito (dimensionless): 0.000625
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.624806
 - ap in component Ito (dimensionless): 0.000319
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.700383
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.938300
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999896
 - jca in component ICaL (dimensionless): 0.999980
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001572
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.327991
 - xs1 in component IKs (dimensionless): 0.235153
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997350
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
19:41:07 (27193): called boinc_finish(0)

</stderr_txt>
]]>