𝕏

Task 54874072

Name HuVeMOp_20240626195229486943_ORdGradInc_k_24-Pueyo_APDR-conf_588_0
Workunit 26055571
Created 26 Jun 2024, 17:53:55 UTC
Sent 26 Jun 2024, 19:22:56 UTC
Report deadline 30 Jun 2024, 4:58:56 UTC
Received 26 Jun 2024, 23:58:04 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 238678
Run time 3 hours 9 min 7 sec
CPU time 2 hours 31 min 27 sec
Validate state Valid
Credit 61.54
Device peak FLOPS 3.99 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.14 MB
Peak swap size 6.20 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626195229486943_ORdGradInc_k_24-Pueyo_APDR-conf_588.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626195229486943_ORdGradInc_k_24-Pueyo_APDR-conf_588_0_r591913955_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626195229486943_ORdGradInc_k_24-Pueyo_APDR-conf_588_0_r591913955_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 97.341875
     * GNaL_b in INaL: 0.006673
     * Gto_b in Ito: 0.081359
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031831
     * GKs_b in IKs: 0.001871
     * GK1_b in IK1: 0.151180
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 67.992341
     * GKb_b in IKb: 0.004021
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.048391
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11620664, states[0] = -41.713339, states[40]= 0.000096
Saving checkpoint... 
Iteration: 23896413, states[0] = -95.165462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35965876, states[0] = -95.161302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48178198, states[0] = -94.842327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 60023642, states[0] = 20.835862, states[40]= 0.007491
Saving checkpoint... 
Iteration: 72261654, states[0] = -95.028488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84748500, states[0] = -95.007121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97459136, states[0] = -95.124585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 109787152, states[0] = -95.045738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 122339549, states[0] = -95.081898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 134539369, states[0] = 16.215583, states[40]= 0.005269
Saving checkpoint... 
Iteration: 147080068, states[0] = -1.474971, states[40]= 0.004017
Saving checkpoint... 
Iteration: 159489274, states[0] = -95.123402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 172101621, states[0] = -18.842468, states[40]= 0.001055
Saving checkpoint... 
Iteration: 184441125, states[0] = -95.114662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 196708526, states[0] = -94.930003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 209325614, states[0] = -95.070508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 221967228, states[0] = -95.119110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 234338363, states[0] = -95.077879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 246964798, states[0] = -95.118589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 259597114, states[0] = -14.636877, states[40]= 0.001508
Saving checkpoint... 
Iteration: 272241024, states[0] = -94.986116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 284666319, states[0] = -92.081855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 296886694, states[0] = -95.099155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 309449220, states[0] = -95.115651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 321704109, states[0] = -94.920549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 334381446, states[0] = -95.097237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346465047, states[0] = -95.118475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 358672706, states[0] = -94.382448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 370200679, states[0] = -94.913318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 382447507, states[0] = -95.115255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 394881328, states[0] = -95.097149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 407266647, states[0] = -95.019479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 419571291, states[0] = 3.312358, states[40]= 0.004579
Saving checkpoint... 
Iteration: 432400002, states[0] = -95.103412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 445266230, states[0] = -95.018977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 457637666, states[0] = -54.391325, states[40]= 0.000014
Saving checkpoint... 
Iteration: 470094238, states[0] = -12.039393, states[40]= 0.001926
Saving checkpoint... 
Iteration: 482589569, states[0] = -8.076818, states[40]= 0.002721
Saving checkpoint... 
Iteration: 495121822, states[0] = -37.789282, states[40]= 0.000182
Saving checkpoint... 
Iteration: 507187633, states[0] = -94.879442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 519782375, states[0] = -95.035999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 532044645, states[0] = 14.340930, states[40]= 0.005080
Saving checkpoint... 
Iteration: 543429734, states[0] = -95.111333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 555634528, states[0] = -50.940444, states[40]= 0.000025
Saving checkpoint... 
Iteration: 568137294, states[0] = -53.979089, states[40]= 0.000015
Saving checkpoint... 
Iteration: 580394038, states[0] = -95.101429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 592782875, states[0] = -95.036438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 605280539, states[0] = -95.034144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 617513853, states[0] = 22.883306, states[40]= 0.022510
Saving checkpoint... 
Iteration: 629977443, states[0] = -95.120251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 642115160, states[0] = -31.420210, states[40]= 0.000412
Saving checkpoint... 
Iteration: 654548615, states[0] = 12.854822, states[40]= 0.004998
Saving checkpoint... 
Iteration: 667176223, states[0] = -94.691581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 679545728, states[0] = 13.939130, states[40]= 0.005054
Saving checkpoint... 
Iteration: 692222592, states[0] = -94.955796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 704866301, states[0] = -95.091021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 717267576, states[0] = -95.020339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 729847250, states[0] = -95.082149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742571283, states[0] = 3.316363, states[40]= 0.004580
Saving checkpoint... 
Iteration: 755108668, states[0] = -25.347864, states[40]= 0.000704
Saving checkpoint... 
Iteration: 767550030, states[0] = 12.316500, states[40]= 0.004977
Saving checkpoint... 
Iteration: 780096478, states[0] = -14.052949, states[40]= 0.001593
Saving checkpoint... 
Iteration: 792526634, states[0] = 20.269895, states[40]= 0.006659
Saving checkpoint... 
Iteration: 804995390, states[0] = -95.122600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 817786521, states[0] = -95.039756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 830561706, states[0] = 7.646069, states[40]= 0.004830
Saving checkpoint... 
Iteration: 843072003, states[0] = 2.962314, states[40]= 0.004550
Saving checkpoint... 
Iteration: 855539756, states[0] = 16.110724, states[40]= 0.005251
Saving checkpoint... 
Iteration: 867920762, states[0] = -95.108947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 880463273, states[0] = -95.117834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 893133035, states[0] = -49.319738, states[40]= 0.000032
Saving checkpoint... 
Iteration: 905846972, states[0] = -95.081897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 918325224, states[0] = -95.069526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 930710298, states[0] = -94.932630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 943418782, states[0] = -95.108393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 955811304, states[0] = -95.060080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 968442819, states[0] = -95.113938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 980929209, states[0] = -95.110936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 993653559, states[0] = -74.079243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1006191379, states[0] = -94.891210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1018656106, states[0] = -78.053675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1030811804, states[0] = -95.060394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1043120721, states[0] = -36.719731, states[40]= 0.000211
Saving checkpoint... 
Iteration: 1055756102, states[0] = -95.006340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1067865002, states[0] = -95.090239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1079983224, states[0] = -95.120807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1092291647, states[0] = -95.044235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1104604979, states[0] = -21.919808, states[40]= 0.000864
Saving checkpoint... 
Iteration: 1117211464, states[0] = -94.934796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1129291769, states[0] = -95.044320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1140642379, states[0] = -59.702158, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1153093177, states[0] = -11.106407, states[40]= 0.002099
Saving checkpoint... 
Iteration: 1165386540, states[0] = -95.098531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1177671646, states[0] = -94.211323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1190257056, states[0] = -95.007464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1203054500, states[0] = 10.582281, states[40]= 0.004922
Saving checkpoint... 
Iteration: 1215540535, states[0] = 15.834332, states[40]= 0.005217
Saving checkpoint... 
Iteration: 1227982450, states[0] = -95.120604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1240667044, states[0] = -92.553073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253220386, states[0] = -94.951488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1265730654, states[0] = -94.969215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1278301579, states[0] = -95.052471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1290974187, states[0] = -95.119343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1303551026, states[0] = 11.934775, states[40]= 0.004963
Saving checkpoint... 
Iteration: 1315377648, states[0] = -95.095194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1327714872, states[0] = -94.941220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1340078765, states[0] = -0.652697, states[40]= 0.004138
Saving checkpoint... 
Iteration: 1352267773, states[0] = -95.020161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1364925252, states[0] = -95.109750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1377522168, states[0] = 21.369309, states[40]= 0.008194
Saving checkpoint... 
Iteration: 1390072042, states[0] = 2.943130, states[40]= 0.004548
Saving checkpoint... 
Iteration: 1402601802, states[0] = -18.967117, states[40]= 0.001045
Saving checkpoint... 
Iteration: 1414852124, states[0] = -95.084141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1427489732, states[0] = -95.121479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1439990470, states[0] = -95.121568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1452385712, states[0] = -95.098060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1464715736, states[0] = -94.942766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1477012766, states[0] = 23.064342, states[40]= 0.027957
Saving checkpoint... 
Iteration: 1489393607, states[0] = -95.100717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1501870289, states[0] = -2.459311, states[40]= 0.004182
Saving checkpoint... 
Iteration: 1514535140, states[0] = -77.628041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1526841836, states[0] = -89.980507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1539561850, states[0] = -95.372490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1551463859, states[0] = -95.199569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1563877684, states[0] = -95.400230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1576335952, states[0] = -83.544501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1588804309, states[0] = 31.953231, states[40]= 0.130906
Saving checkpoint... 
Iteration: 1601366662, states[0] = -95.398574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1613376080, states[0] = -95.408124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1625706389, states[0] = 27.180812, states[40]= 0.107915
Saving checkpoint... 
Iteration: 1637891953, states[0] = -95.291437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1650489578, states[0] = -95.286610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1662782413, states[0] = -95.270367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1675400820, states[0] = -95.310441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1687271825, states[0] = -6.384856, states[40]= 0.003492
Saving checkpoint... 
Iteration: 1699709091, states[0] = -95.326092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1711751620, states[0] = -95.386570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1723795525, states[0] = -95.425300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1736437324, states[0] = 14.356148, states[40]= 0.006259
Saving checkpoint... 
Iteration: 1749069767, states[0] = -4.619708, states[40]= 0.003903
Saving checkpoint... 
Iteration: 1761120090, states[0] = -59.917515, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1773623798, states[0] = 19.989741, states[40]= 0.008638
Saving checkpoint... 
Iteration: 1786033041, states[0] = -79.158135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1798631422, states[0] = -76.354234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1810981851, states[0] = -95.176743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1823484938, states[0] = -95.161463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1835677031, states[0] = -94.816289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1847960313, states[0] = -95.137047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1859691779, states[0] = -94.906717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1872024829, states[0] = 20.640125, states[40]= 0.007112
Saving checkpoint... 
Iteration: 1883995959, states[0] = -95.129161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1896187105, states[0] = -94.882122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1908310942, states[0] = -95.062785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1920391031, states[0] = -95.102090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1932625672, states[0] = -41.718047, states[40]= 0.000103
Saving checkpoint... 
Iteration: 1944932481, states[0] = -95.112296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1957223896, states[0] = -94.958150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1969472674, states[0] = -95.119256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1981879120, states[0] = -95.095716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1993575814, states[0] = 0.988658, states[40]= 0.004351
Saving checkpoint... 
Iteration: 2005765026, states[0] = -95.016771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2016983187, states[0] = -95.120319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2029380724, states[0] = -95.095955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2041779096, states[0] = -95.031821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2053412991, states[0] = -95.106159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2065533884, states[0] = 18.106525, states[40]= 0.005632
Saving checkpoint... 
Iteration: 2077722261, states[0] = -94.954302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2089864238, states[0] = -95.089230, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.998186
 - CaMKt in component CaMK (millimolar): 0.006990
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.560935
 - nass in component intracellular_ions (millimolar): 6.560996
 - ki in component intracellular_ions (millimolar): 145.417158
 - kss in component intracellular_ions (millimolar): 145.417137
 - cansr in component intracellular_ions (millimolar): 1.309734
 - cajsr in component intracellular_ions (millimolar): 1.271431
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003583
 - hf in component INa (dimensionless): 0.881662
 - hs in component INa (dimensionless): 0.881658
 - j in component INa (dimensionless): 0.881628
 - hsp in component INa (dimensionless): 0.728968
 - jp in component INa (dimensionless): 0.881608
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.711640
 - hLp in component INaL (dimensionless): 0.452406
 - a in component Ito (dimensionless): 0.000619
 - iF in component Ito (dimensionless): 0.999872
 - iS in component Ito (dimensionless): 0.618823
 - ap in component Ito (dimensionless): 0.000316
 - iFp in component Ito (dimensionless): 0.999872
 - iSp in component Ito (dimensionless): 0.693131
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.932451
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999877
 - jca in component ICaL (dimensionless): 0.999976
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001597
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.333539
 - xs1 in component IKs (dimensionless): 0.246919
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997312
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
19:57:45 (5316): called boinc_finish(0)

</stderr_txt>
]]>


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