𝕏

Task 54861262

Name HuVeMOp_20240626184047074591_ORdGradInc_k_24-Pueyo_APDR-conf_801_1
Workunit 26049189
Created 26 Jun 2024, 16:40:51 UTC
Sent 26 Jun 2024, 18:20:55 UTC
Report deadline 30 Jun 2024, 3:56:55 UTC
Received 26 Jun 2024, 22:59:08 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 232674
Run time 2 hours 32 min 41 sec
CPU time 2 hours 29 min 48 sec
Validate state Valid
Credit 59.15
Device peak FLOPS 5.37 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.87 MB
Peak swap size 32.60 GB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.24.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626184047074591_ORdGradInc_k_24-Pueyo_APDR-conf_801.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626184047074591_ORdGradInc_k_24-Pueyo_APDR-conf_801_1_r2013221279_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626184047074591_ORdGradInc_k_24-Pueyo_APDR-conf_801_1_r2013221279_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 122.707284
     * GNaL_b in INaL: 0.005846
     * Gto_b in Ito: 0.079149
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.034066
     * GKs_b in IKs: 0.001925
     * GK1_b in IK1: 0.145322
     * Gncx_b in INaCa_i: 0.000956
     * Pnak_b in INaK: 69.574484
     * GKb_b in IKb: 0.003864
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033414
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 14830383, states[0] = -94.959050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 31575294, states[0] = -4.519327, states[40]= 0.003621
Saving checkpoint... 
Iteration: 47908051, states[0] = -94.932554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 63976711, states[0] = -94.935645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 80819804, states[0] = -94.875036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 98661912, states[0] = -94.101667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 114210055, states[0] = -94.735408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 131682807, states[0] = -94.673375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 148247868, states[0] = -94.795669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 162814076, states[0] = -94.861183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 179420928, states[0] = -94.907426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 196930526, states[0] = -94.909481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 213113740, states[0] = -40.211323, states[40]= 0.000118
Saving checkpoint... 
Iteration: 228560899, states[0] = 5.164851, states[40]= 0.004893
Saving checkpoint... 
Iteration: 246151911, states[0] = -87.900140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 261748587, states[0] = -94.795126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 278630364, states[0] = -58.634337, states[40]= 0.000006
Saving checkpoint... 
Iteration: 296050252, states[0] = 10.030521, states[40]= 0.005171
Saving checkpoint... 
Iteration: 311456177, states[0] = -94.914292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 327229610, states[0] = -94.766533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 343592118, states[0] = -18.118436, states[40]= 0.001131
Saving checkpoint... 
Iteration: 361048777, states[0] = 10.664933, states[40]= 0.005211
Saving checkpoint... 
Iteration: 377487533, states[0] = -94.919106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 395067288, states[0] = 1.864144, states[40]= 0.004610
Saving checkpoint... 
Iteration: 411919303, states[0] = -94.906287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 427657569, states[0] = -92.748940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 444745390, states[0] = -94.790539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 462227820, states[0] = -94.763472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 478466450, states[0] = -94.915944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 494089282, states[0] = -15.263011, states[40]= 0.001471
Saving checkpoint... 
Iteration: 511124338, states[0] = -51.801984, states[40]= 0.000019
Saving checkpoint... 
Iteration: 528118272, states[0] = -45.064421, states[40]= 0.000057
Saving checkpoint... 
Iteration: 544309821, states[0] = -94.856943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 562628518, states[0] = -56.525111, states[40]= 0.000009
Saving checkpoint... 
Iteration: 577644605, states[0] = -76.920415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 594402469, states[0] = -94.901529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 610148567, states[0] = -83.086416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 625410238, states[0] = -94.903752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641499119, states[0] = -94.920407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 656774708, states[0] = -94.826079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 672200468, states[0] = -94.711323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 688690443, states[0] = -94.689292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 703706194, states[0] = -94.723196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 719789145, states[0] = -94.840041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 733487388, states[0] = -94.918885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 749384486, states[0] = -94.895578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 764504576, states[0] = 31.523805, states[40]= 0.141910
Saving checkpoint... 
Iteration: 780096893, states[0] = -22.959320, states[40]= 0.000778
Saving checkpoint... 
Iteration: 796314556, states[0] = -94.860184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 811809443, states[0] = -94.856515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 827405373, states[0] = -94.902255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 842782510, states[0] = -94.833794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 858860095, states[0] = -94.885778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 873791777, states[0] = -94.842293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 889632598, states[0] = -61.213555, states[40]= 0.000004
Saving checkpoint... 
Iteration: 905267099, states[0] = -94.817687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 920415915, states[0] = -94.905122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 935198295, states[0] = -94.706533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 950938723, states[0] = -94.910508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 966322873, states[0] = -94.865659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 982607471, states[0] = -33.704450, states[40]= 0.000286
Saving checkpoint... 
Iteration: 997539026, states[0] = 14.676369, states[40]= 0.005631
Saving checkpoint... 
Iteration: 1013973638, states[0] = -94.916774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1029015371, states[0] = 22.159961, states[40]= 0.018969
Saving checkpoint... 
Iteration: 1045482104, states[0] = -94.917990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1060307225, states[0] = -94.854729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1074872399, states[0] = -94.890852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1091337228, states[0] = -94.874195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1106586081, states[0] = -12.117574, states[40]= 0.001988
Saving checkpoint... 
Iteration: 1122047492, states[0] = 11.211501, states[40]= 0.005248
Saving checkpoint... 
Iteration: 1137262018, states[0] = -94.811677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1152307517, states[0] = -94.854896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1168243694, states[0] = -94.787722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1183798392, states[0] = -94.847727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1198540056, states[0] = 14.268105, states[40]= 0.005567
Saving checkpoint... 
Iteration: 1215447884, states[0] = -94.912222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1230658559, states[0] = -93.170477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1246017947, states[0] = 21.534203, states[40]= 0.013221
Saving checkpoint... 
Iteration: 1261957012, states[0] = -94.913896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1276599916, states[0] = -26.023348, states[40]= 0.000623
Saving checkpoint... 
Iteration: 1291593826, states[0] = -19.848524, states[40]= 0.000979
Saving checkpoint... 
Iteration: 1306768514, states[0] = -94.819045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1322705675, states[0] = -94.721788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1338403721, states[0] = -94.901484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1354148266, states[0] = -82.616748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1369152197, states[0] = -88.248587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1385080856, states[0] = -7.370415, states[40]= 0.002984
Saving checkpoint... 
Iteration: 1400380227, states[0] = -94.893671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415839276, states[0] = -94.875144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1431737414, states[0] = -94.778285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1445977394, states[0] = -94.917091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1461669636, states[0] = -94.572564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1478883410, states[0] = -94.894785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493967218, states[0] = -94.915499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1511004501, states[0] = -95.078178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1527977682, states[0] = -17.233947, states[40]= 0.001352
Saving checkpoint... 
Iteration: 1543226195, states[0] = 18.329325, states[40]= 0.008546
Saving checkpoint... 
Iteration: 1559845510, states[0] = -94.820269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1576773306, states[0] = -95.219056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1591836141, states[0] = 13.498444, states[40]= 0.006695
Saving checkpoint... 
Iteration: 1609425448, states[0] = -95.169121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1625480874, states[0] = -22.494090, states[40]= 0.000852
Saving checkpoint... 
Iteration: 1640832235, states[0] = -90.090200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1658680331, states[0] = -95.232253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1674272921, states[0] = -95.226182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1689697290, states[0] = -41.742434, states[40]= 0.000097
Saving checkpoint... 
Iteration: 1707262758, states[0] = -95.216917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1723554085, states[0] = 3.227894, states[40]= 0.005355
Saving checkpoint... 
Iteration: 1738849332, states[0] = 6.192174, states[40]= 0.005685
Saving checkpoint... 
Iteration: 1754934574, states[0] = -95.184569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1772336120, states[0] = -95.186616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1787694229, states[0] = -95.243223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1805120622, states[0] = -52.090088, states[40]= 0.000020
Saving checkpoint... 
Iteration: 1820083858, states[0] = -12.123712, states[40]= 0.002014
Saving checkpoint... 
Iteration: 1837868959, states[0] = -94.917631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1854058002, states[0] = 6.242020, states[40]= 0.004974
Saving checkpoint... 
Iteration: 1869398933, states[0] = -94.910977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1886010266, states[0] = 23.669990, states[40]= 0.051988
Saving checkpoint... 
Iteration: 1903272206, states[0] = -94.826900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1918662495, states[0] = -94.146685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1936826424, states[0] = -94.868872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1951858666, states[0] = -94.885477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1968207191, states[0] = -94.725088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1985889325, states[0] = -94.896886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2001638531, states[0] = -68.449786, states[40]= 0.000001
Saving checkpoint... 
Iteration: 2017861317, states[0] = -94.885771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2035482563, states[0] = -94.917540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2050607809, states[0] = -34.052411, states[40]= 0.000274
Saving checkpoint... 
Iteration: 2068410038, states[0] = -94.902874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2083971314, states[0] = -94.915792, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.795536
 - CaMKt in component CaMK (millimolar): 0.006669
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.614471
 - nass in component intracellular_ions (millimolar): 6.614531
 - ki in component intracellular_ions (millimolar): 145.365841
 - kss in component intracellular_ions (millimolar): 145.365821
 - cansr in component intracellular_ions (millimolar): 1.303081
 - cajsr in component intracellular_ions (millimolar): 1.266279
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003658
 - hf in component INa (dimensionless): 0.878144
 - hs in component INa (dimensionless): 0.878139
 - j in component INa (dimensionless): 0.878109
 - hsp in component INa (dimensionless): 0.722340
 - jp in component INa (dimensionless): 0.878089
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.708830
 - hLp in component INaL (dimensionless): 0.454040
 - a in component Ito (dimensionless): 0.000628
 - iF in component Ito (dimensionless): 0.999867
 - iS in component Ito (dimensionless): 0.629016
 - ap in component Ito (dimensionless): 0.000320
 - iFp in component Ito (dimensionless): 0.999867
 - iSp in component Ito (dimensionless): 0.705155
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.940262
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999903
 - jca in component ICaL (dimensionless): 0.999982
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001581
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.334516
 - xs1 in component IKs (dimensionless): 0.227958
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997365
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
23:39:46 (34162): called boinc_finish(0)

</stderr_txt>
]]>