𝕏

Task 54861045

Name HuVeMOp_20240626144554837168_ORdGradInc_k_24-Pueyo_APDR-conf_187_2
Workunit 26040201
Created 26 Jun 2024, 15:20:13 UTC
Sent 26 Jun 2024, 18:08:13 UTC
Report deadline 30 Jun 2024, 3:44:13 UTC
Received 26 Jun 2024, 22:59:08 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 232674
Run time 2 hours 35 min 2 sec
CPU time 2 hours 32 min
Validate state Valid
Credit 60.99
Device peak FLOPS 5.37 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.89 MB
Peak swap size 32.60 GB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.24.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626144554837168_ORdGradInc_k_24-Pueyo_APDR-conf_187.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626144554837168_ORdGradInc_k_24-Pueyo_APDR-conf_187_2_r414786658_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626144554837168_ORdGradInc_k_24-Pueyo_APDR-conf_187_2_r414786658_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 121.032627
     * GNaL_b in INaL: 0.009031
     * Gto_b in Ito: 0.069056
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032895
     * GKs_b in IKs: 0.001770
     * GK1_b in IK1: 0.154537
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 68.574154
     * GKb_b in IKb: 0.003913
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.043862
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 15727271, states[0] = -95.030727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 31002448, states[0] = 44.939784, states[40]= 0.091874
Saving checkpoint... 
Iteration: 47109383, states[0] = -25.543585, states[40]= 0.000715
Saving checkpoint... 
Iteration: 62189555, states[0] = -94.896579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 77070410, states[0] = 4.538187, states[40]= 0.004828
Saving checkpoint... 
Iteration: 91802304, states[0] = -95.041809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 107050870, states[0] = 13.039252, states[40]= 0.005287
Saving checkpoint... 
Iteration: 122775007, states[0] = -95.013859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 138358383, states[0] = -95.068743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 153855009, states[0] = -95.066572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 169185740, states[0] = -94.865637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 184906273, states[0] = -95.084013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 200789077, states[0] = -95.024158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 215577026, states[0] = 1.476902, states[40]= 0.004517
Saving checkpoint... 
Iteration: 231210343, states[0] = -94.921248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 245516165, states[0] = 24.526237, states[40]= 0.017446
Saving checkpoint... 
Iteration: 260207858, states[0] = -94.916593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 275586724, states[0] = -4.410310, states[40]= 0.003558
Saving checkpoint... 
Iteration: 290972750, states[0] = -95.097117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 306068684, states[0] = 5.608952, states[40]= 0.004893
Saving checkpoint... 
Iteration: 321503374, states[0] = 39.268280, states[40]= 0.115945
Saving checkpoint... 
Iteration: 337956051, states[0] = -95.094412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 353012822, states[0] = 25.397946, states[40]= 0.030575
Saving checkpoint... 
Iteration: 368125051, states[0] = -38.901872, states[40]= 0.000161
Saving checkpoint... 
Iteration: 383738947, states[0] = -94.967596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 399964874, states[0] = -95.095838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 415260739, states[0] = -94.995525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 433308276, states[0] = -95.038730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 449508642, states[0] = 27.279218, states[40]= 0.072140
Saving checkpoint... 
Iteration: 465080083, states[0] = -0.211988, states[40]= 0.004296
Saving checkpoint... 
Iteration: 481618818, states[0] = -32.834925, states[40]= 0.000361
Saving checkpoint... 
Iteration: 499504054, states[0] = 36.010101, states[40]= 0.126867
Saving checkpoint... 
Iteration: 514583537, states[0] = -2.293921, states[40]= 0.003962
Saving checkpoint... 
Iteration: 533009667, states[0] = 26.632454, states[40]= 0.058217
Saving checkpoint... 
Iteration: 548209635, states[0] = -94.919672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 564423236, states[0] = -95.087663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 579266061, states[0] = -95.001385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 597353276, states[0] = -95.064379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 613506985, states[0] = 28.899516, states[40]= 0.099454
Saving checkpoint... 
Iteration: 628936918, states[0] = -95.090648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 646584605, states[0] = -2.980144, states[40]= 0.003838
Saving checkpoint... 
Iteration: 662045388, states[0] = 15.248568, states[40]= 0.005447
Saving checkpoint... 
Iteration: 679734952, states[0] = -94.961643, states[40]= 0.000000
Saving checkpoint... 
Iteration: 696464169, states[0] = -95.095583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 710008398, states[0] = 27.465027, states[40]= 0.075840
Saving checkpoint... 
Iteration: 728544095, states[0] = 15.741480, states[40]= 0.005500
Saving checkpoint... 
Iteration: 744744745, states[0] = -94.975458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 762162278, states[0] = -87.474010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 778865131, states[0] = -95.069395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 795146732, states[0] = -63.664003, states[40]= 0.000003
Saving checkpoint... 
Iteration: 812438404, states[0] = -95.090865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 827869880, states[0] = -95.071259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 844867895, states[0] = -95.070472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 862351188, states[0] = -95.063291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 878976167, states[0] = -95.097308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 893879094, states[0] = -95.074654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 912201800, states[0] = -94.904766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 928090395, states[0] = -7.111186, states[40]= 0.002979
Saving checkpoint... 
Iteration: 945278127, states[0] = -95.013539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 960162310, states[0] = -87.520045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 977705837, states[0] = -94.912419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 993092726, states[0] = -8.977251, states[40]= 0.002571
Saving checkpoint... 
Iteration: 1009147324, states[0] = -64.425842, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1024591348, states[0] = -7.860552, states[40]= 0.002814
Saving checkpoint... 
Iteration: 1040696433, states[0] = -94.894062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1056130998, states[0] = -45.119629, states[40]= 0.000064
Saving checkpoint... 
Iteration: 1071005877, states[0] = 30.676826, states[40]= 0.117753
Saving checkpoint... 
Iteration: 1087778964, states[0] = -95.014271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1102702619, states[0] = -94.906250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1117926400, states[0] = -95.088129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1132566317, states[0] = 6.685126, states[40]= 0.004962
Saving checkpoint... 
Iteration: 1148937720, states[0] = -95.090563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1164752902, states[0] = -94.985809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1180004849, states[0] = 33.190601, states[40]= 0.128394
Saving checkpoint... 
Iteration: 1196117002, states[0] = -31.116223, states[40]= 0.000440
Saving checkpoint... 
Iteration: 1210682165, states[0] = -94.839274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1226617047, states[0] = -31.158623, states[40]= 0.000438
Saving checkpoint... 
Iteration: 1241410452, states[0] = -95.084147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1257603867, states[0] = -18.920566, states[40]= 0.001070
Saving checkpoint... 
Iteration: 1273148508, states[0] = -65.977146, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1288098861, states[0] = -14.324214, states[40]= 0.001577
Saving checkpoint... 
Iteration: 1304343816, states[0] = -95.059527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1318948950, states[0] = -95.092667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1334454170, states[0] = -95.093600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1350023023, states[0] = 22.803384, states[40]= 0.009047
Saving checkpoint... 
Iteration: 1365119860, states[0] = -33.828037, states[40]= 0.000320
Saving checkpoint... 
Iteration: 1381428371, states[0] = -95.088448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1396871652, states[0] = -95.071668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1412717883, states[0] = -94.933922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1428954953, states[0] = -95.093692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1443187146, states[0] = -94.870045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1458239647, states[0] = -94.968070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1473661841, states[0] = -86.825593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1489662453, states[0] = -87.724505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1505809821, states[0] = -40.582912, states[40]= 0.000120
Saving checkpoint... 
Iteration: 1520964520, states[0] = -95.331350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1535793654, states[0] = -25.485166, states[40]= 0.000713
Saving checkpoint... 
Iteration: 1551827314, states[0] = -95.314407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1567024414, states[0] = -62.890360, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1581710665, states[0] = -45.290267, states[40]= 0.000065
Saving checkpoint... 
Iteration: 1597545024, states[0] = 11.714961, states[40]= 0.006181
Saving checkpoint... 
Iteration: 1613155622, states[0] = 6.038054, states[40]= 0.005619
Saving checkpoint... 
Iteration: 1627919769, states[0] = -57.224824, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1643853633, states[0] = -95.065421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1658465891, states[0] = -0.328731, states[40]= 0.004834
Saving checkpoint... 
Iteration: 1672729027, states[0] = -95.332445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1688165754, states[0] = -0.242738, states[40]= 0.004849
Saving checkpoint... 
Iteration: 1703446774, states[0] = 10.763085, states[40]= 0.006078
Saving checkpoint... 
Iteration: 1718793339, states[0] = -26.483031, states[40]= 0.000661
Saving checkpoint... 
Iteration: 1734807225, states[0] = -95.299379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1749604619, states[0] = 35.012025, states[40]= 0.108219
Saving checkpoint... 
Iteration: 1765106405, states[0] = -95.297973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1780519155, states[0] = 23.188006, states[40]= 0.013653
Saving checkpoint... 
Iteration: 1795126646, states[0] = -95.329430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1810977080, states[0] = -95.151341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1824862404, states[0] = -95.105079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1840993735, states[0] = -95.122617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1858299676, states[0] = -95.045883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1873144164, states[0] = -61.250621, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1889538377, states[0] = 17.786835, states[40]= 0.005836
Saving checkpoint... 
Iteration: 1906971492, states[0] = -95.099522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1922497830, states[0] = -95.101743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1938581040, states[0] = -0.812447, states[40]= 0.004209
Saving checkpoint... 
Iteration: 1955815687, states[0] = -95.043853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1971000609, states[0] = 40.943773, states[40]= 0.002192
Saving checkpoint... 
Iteration: 1988381940, states[0] = -95.075413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2004595340, states[0] = -11.201642, states[40]= 0.002113
Saving checkpoint... 
Iteration: 2019812506, states[0] = -95.040990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2036962794, states[0] = -95.094758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2053047245, states[0] = 14.533081, states[40]= 0.005382
Saving checkpoint... 
Iteration: 2068271818, states[0] = -95.006733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2085692167, states[0] = -94.884251, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.975608
 - CaMKt in component CaMK (millimolar): 0.006693
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.600519
 - nass in component intracellular_ions (millimolar): 6.600579
 - ki in component intracellular_ions (millimolar): 145.382280
 - kss in component intracellular_ions (millimolar): 145.382259
 - cansr in component intracellular_ions (millimolar): 1.295557
 - cajsr in component intracellular_ions (millimolar): 1.257485
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003592
 - hf in component INa (dimensionless): 0.881275
 - hs in component INa (dimensionless): 0.881270
 - j in component INa (dimensionless): 0.881242
 - hsp in component INa (dimensionless): 0.728236
 - jp in component INa (dimensionless): 0.881223
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.711002
 - hLp in component INaL (dimensionless): 0.451623
 - a in component Ito (dimensionless): 0.000620
 - iF in component Ito (dimensionless): 0.999871
 - iS in component Ito (dimensionless): 0.617249
 - ap in component Ito (dimensionless): 0.000316
 - iFp in component Ito (dimensionless): 0.999871
 - iSp in component Ito (dimensionless): 0.690538
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.927421
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999859
 - jca in component ICaL (dimensionless): 0.999975
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001562
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.355044
 - xs1 in component IKs (dimensionless): 0.253387
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997318
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
23:12:40 (33932): called boinc_finish(0)

</stderr_txt>
]]>


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