𝕏

Task 54860327

Name HuVeMOp_20240626170832100293_ORdGradInc_k_24-Drouin_MID_3000-conf_791_0
Workunit 26048955
Created 26 Jun 2024, 15:11:13 UTC
Sent 26 Jun 2024, 18:01:47 UTC
Report deadline 29 Jun 2024, 18:01:47 UTC
Received 27 Jun 2024, 23:20:49 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 220966
Run time 1 hours 44 min 44 sec
CPU time 1 hours 12 min 24 sec
Validate state Invalid
Credit 0.00
Device peak FLOPS 4.43 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.02 MB
Peak swap size 5.27 MB
Peak disk usage 0.02 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626170832100293_ORdGradInc_k_24-Drouin_MID_3000-conf_791.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626170832100293_ORdGradInc_k_24-Drouin_MID_3000-conf_791_0_r342203924_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626170832100293_ORdGradInc_k_24-Drouin_MID_3000-conf_791_0_r342203924_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.189758
     * GNaL_b in INaL: 0.009116
     * Gto_b in Ito: 0.080876
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.032817
     * GKs_b in IKs: 0.001757
     * GK1_b in IK1: 0.156492
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 62.290441
     * GKb_b in IKb: 0.003843
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.038197
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11303848, states[0] = -94.174163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 20704228, states[0] = -94.156833, states[40]= 0.000001
Saving checkpoint... 
Iteration: 34459133, states[0] = -94.147298, states[40]= 0.000001
Saving checkpoint... 
Iteration: 44904489, states[0] = -94.161852, states[40]= 0.000001
Saving checkpoint... 
Iteration: 53691681, states[0] = -94.188329, states[40]= 0.000001
Saving checkpoint... 
Iteration: 63104503, states[0] = 14.834603, states[40]= 0.000076
Saving checkpoint... 
Iteration: 67898539, states[0] = -31.214915, states[40]= 0.010940
Saving checkpoint... 
Iteration: 82561588, states[0] = 29.204009, states[40]= 0.000001
Saving checkpoint... 
Iteration: 89788128, states[0] = -94.204304, states[40]= 0.000001
Saving checkpoint... 
Iteration: 102828558, states[0] = -94.237167, states[40]= 0.000001
Saving checkpoint... 
Iteration: 115466384, states[0] = -94.196844, states[40]= 0.000001
Saving checkpoint... 
Iteration: 126962896, states[0] = -94.246315, states[40]= 0.000001
Saving checkpoint... 
Iteration: 136925966, states[0] = -43.166476, states[40]= 0.003343
Saving checkpoint... 
Iteration: 150111017, states[0] = 10.953683, states[40]= 0.000269
Saving checkpoint... 
Iteration: 161711587, states[0] = -94.228915, states[40]= 0.000001
Saving checkpoint... 
Iteration: 173657513, states[0] = -94.235460, states[40]= 0.000001
Saving checkpoint... 
Iteration: 185390168, states[0] = -94.254977, states[40]= 0.000001
Saving checkpoint... 
Iteration: 197505574, states[0] = -94.250618, states[40]= 0.000001
Saving checkpoint... 
Iteration: 209650524, states[0] = -94.237277, states[40]= 0.000001
Saving checkpoint... 
Iteration: 218753275, states[0] = -94.226624, states[40]= 0.000001
Saving checkpoint... 
Iteration: 230100731, states[0] = -94.071406, states[40]= 0.000001
Saving checkpoint... 
Iteration: 242318296, states[0] = -94.250748, states[40]= 0.000001
Saving checkpoint... 
Iteration: 253783470, states[0] = 36.167195, states[40]= 0.008643
Saving checkpoint... 
Iteration: 262103502, states[0] = -94.241658, states[40]= 0.000001
Saving checkpoint... 
Iteration: 274242753, states[0] = -94.227141, states[40]= 0.000001
Saving checkpoint... 
Iteration: 283975152, states[0] = -86.025915, states[40]= 0.000007
Saving checkpoint... 
Iteration: 295637642, states[0] = 0.067612, states[40]= 0.002107
Saving checkpoint... 
Iteration: 307267465, states[0] = -94.223697, states[40]= 0.000001
Saving checkpoint... 
Iteration: 318930530, states[0] = -94.253780, states[40]= 0.000001
Saving checkpoint... 
Iteration: 330961328, states[0] = -94.252307, states[40]= 0.000001
Saving checkpoint... 
Iteration: 342575411, states[0] = -93.996084, states[40]= 0.000001
Saving checkpoint... 
Iteration: 354551169, states[0] = -93.906803, states[40]= 0.000001
Saving checkpoint... 
Iteration: 366910755, states[0] = -94.253004, states[40]= 0.000001
Saving checkpoint... 
Iteration: 378781437, states[0] = -94.240695, states[40]= 0.000001
Saving checkpoint... 
Iteration: 387237275, states[0] = -26.753083, states[40]= 0.019167
Saving checkpoint... 
Iteration: 399414861, states[0] = -34.706549, states[40]= 0.008702
Saving checkpoint... 
Iteration: 411099414, states[0] = 15.179107, states[40]= 0.000100
Saving checkpoint... 
Iteration: 422485117, states[0] = -94.248282, states[40]= 0.000001
Saving checkpoint... 
Iteration: 434152849, states[0] = -94.156804, states[40]= 0.000001
Saving checkpoint... 
Iteration: 445787077, states[0] = 34.635131, states[40]= 0.009076
Saving checkpoint... 
Iteration: 457961005, states[0] = -66.944542, states[40]= 0.000125
Saving checkpoint... 
Iteration: 469775183, states[0] = 38.531704, states[40]= 0.014268
Saving checkpoint... 
Iteration: 477217455, states[0] = -26.775180, states[40]= 0.018456
Saving checkpoint... 
Iteration: 483231611, states[0] = -26.997025, states[40]= 0.018653
Saving checkpoint... 
Iteration: 497217846, states[0] = -94.212191, states[40]= 0.000001
Saving checkpoint... 
Iteration: 509845278, states[0] = -94.210405, states[40]= 0.000001
Saving checkpoint... 
Iteration: 524278970, states[0] = -94.236233, states[40]= 0.000001
Saving checkpoint... 
Iteration: 538349999, states[0] = -94.209328, states[40]= 0.000001
Saving checkpoint... 
Iteration: 552199212, states[0] = -25.208771, states[40]= 0.018559
Saving checkpoint... 
Iteration: 555618184, states[0] = -94.098932, states[40]= 0.000001
Saving checkpoint... 
Iteration: 564601298, states[0] = -94.063253, states[40]= 0.000001
Saving checkpoint... 
Iteration: 577566053, states[0] = 27.191369, states[40]= 0.000002
Saving checkpoint... 
Iteration: 590418791, states[0] = -94.246917, states[40]= 0.000001
Saving checkpoint... 
Iteration: 602909526, states[0] = -94.201587, states[40]= 0.000001
Saving checkpoint... 
Iteration: 615480647, states[0] = -91.456777, states[40]= 0.000002
Saving checkpoint... 
Iteration: 627735344, states[0] = -94.217913, states[40]= 0.000001
Saving checkpoint... 
Iteration: 640901609, states[0] = -28.172029, states[40]= 0.014433
Saving checkpoint... 
Iteration: 653534966, states[0] = -94.238395, states[40]= 0.000001
Saving checkpoint... 
Iteration: 666211783, states[0] = -26.450139, states[40]= 0.018569
Saving checkpoint... 
Iteration: 679226915, states[0] = -94.218347, states[40]= 0.000001
Saving checkpoint... 
Iteration: 691854221, states[0] = 1.864297, states[40]= 0.011480
Saving checkpoint... 
Iteration: 704654836, states[0] = -94.225277, states[40]= 0.000001
Saving checkpoint... 
Iteration: 717353180, states[0] = 2.310654, states[40]= 0.011624
Saving checkpoint... 
Iteration: 729922445, states[0] = -94.243200, states[40]= 0.000001
Saving checkpoint... 
Iteration: 742324580, states[0] = -94.206547, states[40]= 0.000001
Saving checkpoint... 
Iteration: 755230642, states[0] = -94.212206, states[40]= 0.000001
Saving checkpoint... 
Iteration: 767709772, states[0] = -94.217857, states[40]= 0.000001
Saving checkpoint... 
Iteration: 780701458, states[0] = -94.194110, states[40]= 0.000001
Saving checkpoint... 
Iteration: 793408601, states[0] = -94.196560, states[40]= 0.000001
Saving checkpoint... 
Iteration: 806103499, states[0] = -94.061305, states[40]= 0.000001
Saving checkpoint... 
Iteration: 818816014, states[0] = -94.205324, states[40]= 0.000001
Saving checkpoint... 
Iteration: 831347798, states[0] = 5.583231, states[40]= 0.012496
Saving checkpoint... 
Iteration: 843964859, states[0] = -94.238481, states[40]= 0.000001
Saving checkpoint... 
Iteration: 856600824, states[0] = 14.645596, states[40]= 0.000115
Saving checkpoint... 
Iteration: 869216860, states[0] = -94.201703, states[40]= 0.000001
Saving checkpoint... 
Iteration: 881685977, states[0] = -94.217359, states[40]= 0.000001
Saving checkpoint... 
Iteration: 894706561, states[0] = -94.194396, states[40]= 0.000001
Saving checkpoint... 
Iteration: 906938730, states[0] = -94.238014, states[40]= 0.000001
Saving checkpoint... 
Iteration: 919537969, states[0] = 33.817870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 932438596, states[0] = -94.237234, states[40]= 0.000001
Saving checkpoint... 
Iteration: 944772558, states[0] = -94.206511, states[40]= 0.000001
Saving checkpoint... 
Iteration: 957568210, states[0] = -93.954565, states[40]= 0.000001
Saving checkpoint... 
Iteration: 970268246, states[0] = -94.206684, states[40]= 0.000001
Saving checkpoint... 
Iteration: 982647867, states[0] = -4.770117, states[40]= 0.003072
Saving checkpoint... 
Iteration: 995361827, states[0] = -94.235348, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1008144061, states[0] = -2.879498, states[40]= 0.002777
Saving checkpoint... 
Iteration: 1020588309, states[0] = -94.017188, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1033337081, states[0] = -94.197884, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1045947019, states[0] = -54.527088, states[40]= 0.000777
Saving checkpoint... 
Iteration: 1058701648, states[0] = -94.210816, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1071256563, states[0] = -21.249753, states[40]= 0.029029
Saving checkpoint... 
Iteration: 1083629830, states[0] = -94.106711, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1091819548, states[0] = -94.198059, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1103336738, states[0] = -94.230715, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1115171831, states[0] = -94.160475, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1126372053, states[0] = -94.191705, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1131440328, states[0] = -50.894700, states[40]= 0.001283
Saving checkpoint... 
Iteration: 1134622688, states[0] = -94.091939, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1137058073, states[0] = 29.626804, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1140127178, states[0] = 4.437010, states[40]= 0.001098
Saving checkpoint... 
Iteration: 1143182495, states[0] = -21.688070, states[40]= 0.013905
Saving checkpoint... 
Iteration: 1146466088, states[0] = -72.966025, states[40]= 0.000051
Saving checkpoint... 
Iteration: 1149773767, states[0] = -94.218087, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1152934914, states[0] = -94.232084, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1156113548, states[0] = -94.217958, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1159438132, states[0] = -94.183980, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1162597669, states[0] = 15.851456, states[40]= 0.000084
Saving checkpoint... 
Iteration: 1165297368, states[0] = -94.197988, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1168187859, states[0] = -94.209969, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1170985906, states[0] = -94.228931, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1173935033, states[0] = -94.231074, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1176618867, states[0] = -94.084850, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1179380678, states[0] = -16.593396, states[40]= 0.006073
Saving checkpoint... 
Iteration: 1182486596, states[0] = -93.009128, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1184948966, states[0] = -94.182808, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1187538985, states[0] = -94.223983, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1190253483, states[0] = -94.210530, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1193137783, states[0] = -94.115295, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1195677165, states[0] = -19.886500, states[40]= 0.010072
Saving checkpoint... 
Iteration: 1198268275, states[0] = -94.200607, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1201517984, states[0] = 33.217299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1204643399, states[0] = -2.558163, states[40]= 0.002714
Saving checkpoint... 
Iteration: 1207522877, states[0] = 34.008768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1210515589, states[0] = 32.580999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1213525170, states[0] = 34.203927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1216765989, states[0] = 15.780828, states[40]= 0.099314
Saving checkpoint... 
Iteration: 1219803292, states[0] = 27.090798, states[40]= 0.012315
Saving checkpoint... 
Iteration: 1222445697, states[0] = -94.181442, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1225221395, states[0] = -94.204456, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1228123978, states[0] = -94.215027, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1230909489, states[0] = -94.230527, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1233766801, states[0] = -94.213959, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1236802384, states[0] = -94.222384, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1239858095, states[0] = -94.228903, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1243101563, states[0] = -94.216930, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1246265215, states[0] = -94.199585, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1249549974, states[0] = 31.722797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1252788516, states[0] = 33.889155, states[40]= 0.009385
Saving checkpoint... 
Iteration: 1255959685, states[0] = -64.462963, states[40]= 0.000181
Saving checkpoint... 
Iteration: 1259119265, states[0] = -94.080168, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1262300384, states[0] = -94.221624, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1265445298, states[0] = -94.228042, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1268671938, states[0] = -94.208356, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1271850872, states[0] = -94.189912, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1283647938, states[0] = -94.210433, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1295263585, states[0] = -94.211271, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1307532340, states[0] = -94.221452, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1319786432, states[0] = -94.195513, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1332619352, states[0] = -94.078749, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1344766513, states[0] = -94.210795, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1353041307, states[0] = 33.382288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1365658542, states[0] = -94.138346, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1377997769, states[0] = -94.222682, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1390724086, states[0] = -27.025882, states[40]= 0.018362
Saving checkpoint... 
Iteration: 1403476765, states[0] = -94.222718, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1416137288, states[0] = 0.233192, states[40]= 0.002068
Saving checkpoint... 
Iteration: 1428616721, states[0] = -94.073142, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1441373371, states[0] = -94.183385, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1454516885, states[0] = -94.219471, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1461355614, states[0] = 0.172376, states[40]= 0.010872
Saving checkpoint... 
Iteration: 1473366626, states[0] = -6.245027, states[40]= 0.007849
Saving checkpoint... 
Iteration: 1485446646, states[0] = -53.284652, states[40]= 0.000924
Saving checkpoint... 
Iteration: 1498418877, states[0] = -94.177191, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.045654
 - CaMKt in component CaMK (millimolar): 0.013469
 - cass in component intracellular_ions (millimolar): 0.000102
 - nai in component intracellular_ions (millimolar): 8.263180
 - nass in component intracellular_ions (millimolar): 8.263355
 - ki in component intracellular_ions (millimolar): 143.333257
 - kss in component intracellular_ions (millimolar): 143.333237
 - cansr in component intracellular_ions (millimolar): 2.225325
 - cajsr in component intracellular_ions (millimolar): 2.228884
 - cai in component intracellular_ions (millimolar): 0.000107
 - m in component INa (dimensionless): 0.003945
 - hf in component INa (dimensionless): 0.864331
 - hs in component INa (dimensionless): 0.864335
 - j in component INa (dimensionless): 0.864358
 - hsp in component INa (dimensionless): 0.697013
 - jp in component INa (dimensionless): 0.864370
 - mL in component INaL (dimensionless): 0.000058
 - hL in component INaL (dimensionless): 0.706241
 - hLp in component INaL (dimensionless): 0.498961
 - a in component Ito (dimensionless): 0.000661
 - iF in component Ito (dimensionless): 0.999849
 - iS in component Ito (dimensionless): 0.937237
 - ap in component Ito (dimensionless): 0.000336
 - iFp in component Ito (dimensionless): 0.999849
 - iSp in component Ito (dimensionless): 0.963188
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.965958
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005417
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.060986
 - xs1 in component IKs (dimensionless): 0.162941
 - xs2 in component IKs (dimensionless): 0.000097
 - xk1 in component IK1 (dimensionless): 0.997553
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
17:20:22 (5300): called boinc_finish(0)

</stderr_txt>
]]>


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