𝕏

Task 54855432

Name HuVeMOp_20240626170549460391_ORdGradInc_k_24-Pueyo_APDR-conf_991_1
Workunit 26046509
Created 26 Jun 2024, 15:08:18 UTC
Sent 26 Jun 2024, 17:12:11 UTC
Report deadline 30 Jun 2024, 2:48:11 UTC
Received 26 Jun 2024, 23:46:48 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 229534
Run time 2 hours 16 min 3 sec
CPU time 2 hours 14 min 56 sec
Validate state Valid
Credit 73.62
Device peak FLOPS 4.00 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.84 MB
Peak swap size 6.39 MB
Peak disk usage 0.27 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626170549460391_ORdGradInc_k_24-Pueyo_APDR-conf_991.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626170549460391_ORdGradInc_k_24-Pueyo_APDR-conf_991_1_r2016003979_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626170549460391_ORdGradInc_k_24-Pueyo_APDR-conf_991_1_r2016003979_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 123.763943
     * GNaL_b in INaL: 0.008317
     * Gto_b in Ito: 0.081356
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033388
     * GKs_b in IKs: 0.001796
     * GK1_b in IK1: 0.170498
     * Gncx_b in INaCa_i: 0.000960
     * Pnak_b in INaK: 63.819500
     * GKb_b in IKb: 0.003813
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032152
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 17135139, states[0] = -54.969019, states[40]= 0.000013
Saving checkpoint... 
Iteration: 33380074, states[0] = -95.133397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 50692869, states[0] = -94.944556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67941672, states[0] = -95.137943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 85187636, states[0] = -94.926774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 102466020, states[0] = -95.138261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 119748135, states[0] = -95.025941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 137055617, states[0] = 10.443791, states[40]= 0.005049
Saving checkpoint... 
Iteration: 154291887, states[0] = -95.069136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 171612229, states[0] = -28.623403, states[40]= 0.000570
Saving checkpoint... 
Iteration: 188949166, states[0] = -95.133342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 206146170, states[0] = -66.371415, states[40]= 0.000002
Saving checkpoint... 
Iteration: 223492174, states[0] = -95.139549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 240853683, states[0] = -95.105611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 257969122, states[0] = -95.136399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 275041992, states[0] = 15.664015, states[40]= 0.005342
Saving checkpoint... 
Iteration: 292284828, states[0] = -95.062686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 309628088, states[0] = -44.384774, states[40]= 0.000074
Saving checkpoint... 
Iteration: 326959241, states[0] = -95.134794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 344238956, states[0] = -95.012382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 361428393, states[0] = -95.128941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 378766847, states[0] = -95.045665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396004836, states[0] = 30.706012, states[40]= 0.148364
Saving checkpoint... 
Iteration: 413326888, states[0] = -95.092109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 430652337, states[0] = -76.021800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 447943833, states[0] = -95.132013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 465168774, states[0] = -94.500678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 482292267, states[0] = -95.068720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 499373421, states[0] = -95.113274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 516605475, states[0] = -22.281121, states[40]= 0.000870
Saving checkpoint... 
Iteration: 533863742, states[0] = -95.109580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 551198115, states[0] = -94.944264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 568543222, states[0] = 15.217620, states[40]= 0.005295
Saving checkpoint... 
Iteration: 585800854, states[0] = -95.075216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 603109820, states[0] = -26.339100, states[40]= 0.000682
Saving checkpoint... 
Iteration: 620352272, states[0] = -95.104715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 637677599, states[0] = -94.882497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 654994102, states[0] = -95.139444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 672257214, states[0] = -95.035035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 689518742, states[0] = 22.418120, states[40]= 0.011594
Saving checkpoint... 
Iteration: 706853560, states[0] = -95.105230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 724177106, states[0] = -94.877786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 741200695, states[0] = -94.949138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 758517070, states[0] = 22.735699, states[40]= 0.014217
Saving checkpoint... 
Iteration: 775813547, states[0] = -95.083824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 793067060, states[0] = 5.560993, states[40]= 0.004846
Saving checkpoint... 
Iteration: 810394206, states[0] = -95.119929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 827660464, states[0] = -90.028542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 844836292, states[0] = -95.096930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 862099409, states[0] = -16.627656, states[40]= 0.001287
Saving checkpoint... 
Iteration: 879445995, states[0] = -95.132153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 896711576, states[0] = -94.969115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 914031277, states[0] = 19.262994, states[40]= 0.006160
Saving checkpoint... 
Iteration: 931084364, states[0] = -4.032771, states[40]= 0.003642
Saving checkpoint... 
Iteration: 948330984, states[0] = -95.094054, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626170549460391_ORdGradInc_k_24-Pueyo_APDR-conf_991.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626170549460391_ORdGradInc_k_24-Pueyo_APDR-conf_991_1_r2016003979_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626170549460391_ORdGradInc_k_24-Pueyo_APDR-conf_991_1_r2016003979_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 123.763943
     * GNaL_b in INaL: 0.008317
     * Gto_b in Ito: 0.081356
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033388
     * GKs_b in IKs: 0.001796
     * GK1_b in IK1: 0.170498
     * Gncx_b in INaCa_i: 0.000960
     * Pnak_b in INaK: 63.819500
     * GKb_b in IKb: 0.003813
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032152
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 948330984
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -95.094054 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 965150632, states[0] = -73.119141, states[40]= 0.000001
Saving checkpoint... 
Iteration: 981371838, states[0] = -95.112403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 998253303, states[0] = -95.030290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1014879720, states[0] = -95.115177, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031787438, states[0] = -95.064438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1048635397, states[0] = -52.715332, states[40]= 0.000020
Saving checkpoint... 
Iteration: 1065432499, states[0] = -95.129386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1082008737, states[0] = 24.956416, states[40]= 0.073628
Saving checkpoint... 
Iteration: 1098839182, states[0] = -95.098247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1115726147, states[0] = -94.993191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1132618788, states[0] = -34.864056, states[40]= 0.000286
Saving checkpoint... 
Iteration: 1149398903, states[0] = -95.121093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1166202669, states[0] = -94.952637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1182842132, states[0] = -95.099656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1199269783, states[0] = -95.048148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1215855587, states[0] = -95.105798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232420646, states[0] = -95.126665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1249030745, states[0] = 19.424040, states[40]= 0.006232
Saving checkpoint... 
Iteration: 1265598588, states[0] = -15.866489, states[40]= 0.001375
Saving checkpoint... 
Iteration: 1282034886, states[0] = 18.120500, states[40]= 0.005775
Saving checkpoint... 
Iteration: 1298574555, states[0] = 1.874020, states[40]= 0.004548
Saving checkpoint... 
Iteration: 1315246422, states[0] = -95.021645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1331908649, states[0] = -95.123643, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1348565452, states[0] = 6.293058, states[40]= 0.004887
Saving checkpoint... 
Iteration: 1365264656, states[0] = -95.042774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1381933143, states[0] = -95.129328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1398678122, states[0] = -94.886359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415323230, states[0] = -95.089390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1431468453, states[0] = -95.135558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1448117098, states[0] = -33.230148, states[40]= 0.000350
Saving checkpoint... 
Iteration: 1464814045, states[0] = -95.083724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1481590808, states[0] = -8.950669, states[40]= 0.002587
Saving checkpoint... 
Iteration: 1498331093, states[0] = -95.093778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1514953604, states[0] = -95.327579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1531611870, states[0] = -47.869026, states[40]= 0.000045
Saving checkpoint... 
Iteration: 1548291280, states[0] = -95.384392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1564934844, states[0] = -85.309446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1581539835, states[0] = -95.349501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1598261098, states[0] = -95.206944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1614901386, states[0] = 51.728000, states[40]= 0.038676
Saving checkpoint... 
Iteration: 1631551599, states[0] = -95.139687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1647919363, states[0] = 21.814587, states[40]= 0.012313
Saving checkpoint... 
Iteration: 1664177084, states[0] = -11.251194, states[40]= 0.002398
Saving checkpoint... 
Iteration: 1680683080, states[0] = -17.564590, states[40]= 0.001322
Saving checkpoint... 
Iteration: 1697407197, states[0] = 27.292500, states[40]= 0.097195
Saving checkpoint... 
Iteration: 1714095041, states[0] = -95.288324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1730521926, states[0] = -63.594040, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1747234889, states[0] = 15.733959, states[40]= 0.006730
Saving checkpoint... 
Iteration: 1763841082, states[0] = -93.589023, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1780472598, states[0] = -95.386567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1797039766, states[0] = 13.457461, states[40]= 0.006314
Saving checkpoint... 
Iteration: 1813616490, states[0] = -35.890647, states[40]= 0.000257
Saving checkpoint... 
Iteration: 1830071955, states[0] = 2.352223, states[40]= 0.004639
Saving checkpoint... 
Iteration: 1846121709, states[0] = -39.070922, states[40]= 0.000162
Saving checkpoint... 
Iteration: 1862466127, states[0] = -95.145971, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626170549460391_ORdGradInc_k_24-Pueyo_APDR-conf_991.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626170549460391_ORdGradInc_k_24-Pueyo_APDR-conf_991_1_r2016003979_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626170549460391_ORdGradInc_k_24-Pueyo_APDR-conf_991_1_r2016003979_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 123.763943
     * GNaL_b in INaL: 0.008317
     * Gto_b in Ito: 0.081356
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033388
     * GKs_b in IKs: 0.001796
     * GK1_b in IK1: 0.170498
     * Gncx_b in INaCa_i: 0.000960
     * Pnak_b in INaK: 63.819500
     * GKb_b in IKb: 0.003813
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032152
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1862466127
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -95.145971 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading resultsTime...
Loading resultsAPD90...
Loading resultsAPD75...
Loading resultsAPD50...
Loading resultsAPD25...
Loading resultsAPD10...
Loading resultsTriangulation...
Loading resultsMaxV...
Loading resultsMinV...
Loading resultsMaxDiffV...
Loading resultsMinDiffV...
Copy resultsTime...
Copy resultsAPD90...
Copy resultsAPD75...
Copy resultsAPD50...
Copy resultsAPD25...
Copy resultsAPD10...
Copy resultsTriangulation...
Copy resultsMaxV...
Copy resultsMinV...
Copy resultsMaxDiffV...
Copy resultsMinDiffV...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1878937692, states[0] = -95.136788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1894708108, states[0] = -94.966695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1911469775, states[0] = -95.138116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1927922952, states[0] = -95.128410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1944606745, states[0] = -23.534753, states[40]= 0.000811
Saving checkpoint... 
Iteration: 1961363507, states[0] = -95.109214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1978133981, states[0] = -51.086096, states[40]= 0.000026
Saving checkpoint... 
Iteration: 1994714249, states[0] = -94.973319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2011167425, states[0] = -94.285858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2027800665, states[0] = -95.074240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2044460861, states[0] = -95.134012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2061249145, states[0] = -95.024586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2078014692, states[0] = 23.170676, states[40]= 0.020644
Saving checkpoint... 
Iteration: 2094925741, states[0] = -95.127260, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -95.015072
 - CaMKt in component CaMK (millimolar): 0.007118
 - cass in component intracellular_ions (millimolar): 0.000075
 - nai in component intracellular_ions (millimolar): 6.784491
 - nass in component intracellular_ions (millimolar): 6.784553
 - ki in component intracellular_ions (millimolar): 145.190713
 - kss in component intracellular_ions (millimolar): 145.190692
 - cansr in component intracellular_ions (millimolar): 1.324561
 - cajsr in component intracellular_ions (millimolar): 1.286316
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003577
 - hf in component INa (dimensionless): 0.881951
 - hs in component INa (dimensionless): 0.881947
 - j in component INa (dimensionless): 0.881920
 - hsp in component INa (dimensionless): 0.729518
 - jp in component INa (dimensionless): 0.881902
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.712842
 - hLp in component INaL (dimensionless): 0.455258
 - a in component Ito (dimensionless): 0.000619
 - iF in component Ito (dimensionless): 0.999872
 - iS in component Ito (dimensionless): 0.620383
 - ap in component Ito (dimensionless): 0.000315
 - iFp in component Ito (dimensionless): 0.999872
 - iSp in component Ito (dimensionless): 0.694861
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.931290
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999873
 - jca in component ICaL (dimensionless): 0.999976
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001663
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.343466
 - xs1 in component IKs (dimensionless): 0.247950
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997307
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
15:49:08 (3004): called boinc_finish(0)

</stderr_txt>
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