𝕏

Task 54855051

Name HuVeMOp_20240626170549460391_ORdGradInc_k_24-Pueyo_APDR-conf_583_1
Workunit 26046319
Created 26 Jun 2024, 15:08:08 UTC
Sent 26 Jun 2024, 17:07:37 UTC
Report deadline 30 Jun 2024, 2:43:37 UTC
Received 29 Jun 2024, 2:44:15 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 214023
Run time 2 hours 57 min 48 sec
CPU time 2 hours 57 min 17 sec
Validate state Valid
Credit 59.07
Device peak FLOPS 3.63 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 3.13 MB
Peak swap size 3.82 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626170549460391_ORdGradInc_k_24-Pueyo_APDR-conf_583.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626170549460391_ORdGradInc_k_24-Pueyo_APDR-conf_583_1_r1702353311_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626170549460391_ORdGradInc_k_24-Pueyo_APDR-conf_583_1_r1702353311_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 116.157996
     * GNaL_b in INaL: 0.005986
     * Gto_b in Ito: 0.094520
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033002
     * GKs_b in IKs: 0.001934
     * GK1_b in IK1: 0.152861
     * Gncx_b in INaCa_i: 0.000947
     * Pnak_b in INaK: 62.808990
     * GKb_b in IKb: 0.003800
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.052988
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12481058, states[0] = -94.986157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24165904, states[0] = -94.154885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 36631688, states[0] = -54.437569, states[40]= 0.000013
Saving checkpoint... 
Iteration: 48689097, states[0] = -94.735967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 61227832, states[0] = -94.807808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 73570171, states[0] = 1.738258, states[40]= 0.004436
Saving checkpoint... 
Iteration: 85693196, states[0] = -94.738179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 98133762, states[0] = -55.931992, states[40]= 0.000010
Saving checkpoint... 
Iteration: 110470672, states[0] = -94.949571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 122923647, states[0] = -94.940246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 135281904, states[0] = -94.869081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 147534831, states[0] = 16.242893, states[40]= 0.005371
Saving checkpoint... 
Iteration: 159683487, states[0] = -94.709563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 172170413, states[0] = -94.462857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 184631328, states[0] = -53.107934, states[40]= 0.000017
Saving checkpoint... 
Iteration: 196931121, states[0] = -94.940810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 209319053, states[0] = -94.897167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 221720299, states[0] = -94.787771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 234103774, states[0] = -25.323803, states[40]= 0.000682
Saving checkpoint... 
Iteration: 246561648, states[0] = 5.953488, states[40]= 0.004722
Saving checkpoint... 
Iteration: 258967552, states[0] = -94.947301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 271370718, states[0] = -94.922947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 283755585, states[0] = -94.839833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 296191894, states[0] = -94.731561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 308405303, states[0] = -94.934254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 320570717, states[0] = 1.569558, states[40]= 0.004416
Saving checkpoint... 
Iteration: 333024377, states[0] = 19.219797, states[40]= 0.006961
Saving checkpoint... 
Iteration: 345396259, states[0] = -94.931610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 357876419, states[0] = -94.925008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 370353225, states[0] = -94.915509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 382829789, states[0] = -94.903460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 395239709, states[0] = -94.818542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 407759427, states[0] = -94.844360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 420262797, states[0] = -94.848261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432599685, states[0] = -21.414340, states[40]= 0.000875
Saving checkpoint... 
Iteration: 445036555, states[0] = 15.679210, states[40]= 0.005261
Saving checkpoint... 
Iteration: 457300056, states[0] = -94.883474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 469574361, states[0] = -0.460211, states[40]= 0.004175
Saving checkpoint... 
Iteration: 482080917, states[0] = -4.721108, states[40]= 0.003449
Saving checkpoint... 
Iteration: 494524867, states[0] = 19.103779, states[40]= 0.006814
Saving checkpoint... 
Iteration: 506553985, states[0] = 9.194242, states[40]= 0.004826
Saving checkpoint... 
Iteration: 518922625, states[0] = -94.938517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 531266099, states[0] = -94.851881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 543528542, states[0] = 18.153592, states[40]= 0.006035
Saving checkpoint... 
Iteration: 555758002, states[0] = -94.842558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 568019429, states[0] = 20.237853, states[40]= 0.009802
Saving checkpoint... 
Iteration: 580478724, states[0] = -94.948662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 592874416, states[0] = -94.924100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 605300378, states[0] = -94.883617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 617613722, states[0] = -34.882315, states[40]= 0.000262
Saving checkpoint... 
Iteration: 629812011, states[0] = -94.892087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641955288, states[0] = -94.945015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 653444256, states[0] = -94.943008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 665879247, states[0] = -94.925804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 678103625, states[0] = -25.178533, states[40]= 0.000689
Saving checkpoint... 
Iteration: 690422430, states[0] = -94.938348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 702451888, states[0] = -94.944378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 714947230, states[0] = -94.943523, states[40]= 0.000000
Saving checkpoint... 
Iteration: 727440953, states[0] = -94.942314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 739834202, states[0] = -94.905688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 751735122, states[0] = -94.811491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 764231328, states[0] = -94.805622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 776617540, states[0] = -38.633242, states[40]= 0.000157
Saving checkpoint... 
Iteration: 788716708, states[0] = -94.780904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 801045654, states[0] = 12.427699, states[40]= 0.004936
Saving checkpoint... 
Iteration: 813595977, states[0] = -17.866277, states[40]= 0.001136
Saving checkpoint... 
Iteration: 825680164, states[0] = -94.693392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 838096633, states[0] = -18.493676, states[40]= 0.001079
Saving checkpoint... 
Iteration: 850416493, states[0] = -94.936798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 862729234, states[0] = -94.802221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 875094718, states[0] = -16.664246, states[40]= 0.001260
Saving checkpoint... 
Iteration: 887330376, states[0] = -94.903434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 899761486, states[0] = -94.846411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 911619001, states[0] = -40.093612, states[40]= 0.000128
Saving checkpoint... 
Iteration: 923841575, states[0] = -94.909473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 936327591, states[0] = -94.901784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 948291477, states[0] = -94.876162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 960677057, states[0] = -94.667392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 973194498, states[0] = -94.736810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 985698446, states[0] = -94.745189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 998044912, states[0] = 12.704247, states[40]= 0.004951
Saving checkpoint... 
Iteration: 1010492833, states[0] = -94.950159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1022832702, states[0] = -94.904653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1035128982, states[0] = -50.543003, states[40]= 0.000026
Saving checkpoint... 
Iteration: 1047027857, states[0] = 18.340952, states[40]= 0.006148
Saving checkpoint... 
Iteration: 1059402815, states[0] = -94.933014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1071802314, states[0] = -94.884765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1083365606, states[0] = -94.920327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1095687260, states[0] = -94.719831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1108117877, states[0] = -38.968464, states[40]= 0.000150
Saving checkpoint... 
Iteration: 1120355506, states[0] = -94.916002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1132749172, states[0] = -94.831061, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1145083491, states[0] = -6.661381, states[40]= 0.003046
Saving checkpoint... 
Iteration: 1157438548, states[0] = -94.941527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1169570338, states[0] = 1.770310, states[40]= 0.004436
Saving checkpoint... 
Iteration: 1181861751, states[0] = -94.918665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1193632939, states[0] = -54.858915, states[40]= 0.000012
Saving checkpoint... 
Iteration: 1205783506, states[0] = -94.868939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1218192834, states[0] = -94.732987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1230565651, states[0] = 4.113184, states[40]= 0.004624
Saving checkpoint... 
Iteration: 1242705180, states[0] = -94.758710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1254835290, states[0] = -94.905915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1266561540, states[0] = 6.002491, states[40]= 0.004724
Saving checkpoint... 
Iteration: 1279098164, states[0] = -19.958646, states[40]= 0.000966
Saving checkpoint... 
Iteration: 1291484476, states[0] = -94.948919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1303757822, states[0] = -94.841804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1315968735, states[0] = -94.946699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1328033700, states[0] = 16.614635, states[40]= 0.005456
Saving checkpoint... 
Iteration: 1339822834, states[0] = -94.898629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1351959745, states[0] = -94.945256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1363838061, states[0] = -94.907326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1376200819, states[0] = -94.749816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1388270291, states[0] = -94.855784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1400724988, states[0] = -94.794870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1412907889, states[0] = -94.934165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1424891347, states[0] = -94.929317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1436703131, states[0] = -94.754472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1448774014, states[0] = -94.859592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1460436646, states[0] = -94.940923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1471664166, states[0] = -93.332124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1483740667, states[0] = -94.819137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1495908792, states[0] = -94.934348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1507928362, states[0] = -72.989553, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1519698688, states[0] = -95.097951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1531237855, states[0] = 13.124662, states[40]= 0.006076
Saving checkpoint... 
Iteration: 1543495932, states[0] = -95.235117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1555429667, states[0] = -95.177989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1567461440, states[0] = -95.219374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1579335966, states[0] = -90.108281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1591014331, states[0] = -58.026851, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1603035814, states[0] = -90.173988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1615049176, states[0] = -94.916223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1626856175, states[0] = -95.223187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1638752560, states[0] = -94.993528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1650559891, states[0] = -95.227713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1662770711, states[0] = -95.079499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1675092792, states[0] = -95.130865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1686981264, states[0] = -20.058810, states[40]= 0.001041
Saving checkpoint... 
Iteration: 1699156666, states[0] = -95.225082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1710998168, states[0] = -38.867126, states[40]= 0.000154
Saving checkpoint... 
Iteration: 1722499020, states[0] = -95.143501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1734511681, states[0] = -95.166240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1746864675, states[0] = -95.232881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1758695485, states[0] = -35.851257, states[40]= 0.000231
Saving checkpoint... 
Iteration: 1771197721, states[0] = -95.258447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1783412135, states[0] = -95.166994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1795346248, states[0] = -94.773433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1807165514, states[0] = -94.453607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1818783134, states[0] = -94.914498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1831197076, states[0] = -94.775078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1843094416, states[0] = -17.568885, states[40]= 0.001169
Saving checkpoint... 
Iteration: 1855372710, states[0] = -94.939212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1867323463, states[0] = -94.910472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1879236921, states[0] = -94.821916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1891464870, states[0] = -94.951550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1903634053, states[0] = -56.370011, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1915745367, states[0] = -94.828356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1928076740, states[0] = -1.966086, states[40]= 0.003952
Saving checkpoint... 
Iteration: 1939793563, states[0] = -94.878637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1951863759, states[0] = -94.919942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1963994038, states[0] = -94.950301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1976028587, states[0] = 18.135872, states[40]= 0.006028
Saving checkpoint... 
Iteration: 1987893308, states[0] = -94.929840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1999306306, states[0] = -94.887275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2011106070, states[0] = -27.524921, states[40]= 0.000579
Saving checkpoint... 
Iteration: 2022987934, states[0] = -94.948908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2035304624, states[0] = -94.885836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2047601804, states[0] = -23.442008, states[40]= 0.000770
Saving checkpoint... 
Iteration: 2059880004, states[0] = -94.925054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2072228382, states[0] = -94.799942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2084013441, states[0] = 21.134411, states[40]= 0.024629
Saving checkpoint... 
Iteration: 2096443540, states[0] = -94.941787, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.826028
 - CaMKt in component CaMK (millimolar): 0.007178
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.828681
 - nass in component intracellular_ions (millimolar): 6.828740
 - ki in component intracellular_ions (millimolar): 145.144795
 - kss in component intracellular_ions (millimolar): 145.144775
 - cansr in component intracellular_ions (millimolar): 1.327257
 - cajsr in component intracellular_ions (millimolar): 1.289402
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003646
 - hf in component INa (dimensionless): 0.878679
 - hs in component INa (dimensionless): 0.878674
 - j in component INa (dimensionless): 0.878646
 - hsp in component INa (dimensionless): 0.723345
 - jp in component INa (dimensionless): 0.878627
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.708393
 - hLp in component INaL (dimensionless): 0.451112
 - a in component Ito (dimensionless): 0.000627
 - iF in component Ito (dimensionless): 0.999868
 - iS in component Ito (dimensionless): 0.623385
 - ap in component Ito (dimensionless): 0.000319
 - iFp in component Ito (dimensionless): 0.999868
 - iSp in component Ito (dimensionless): 0.698904
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.939068
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999896
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001657
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.325983
 - xs1 in component IKs (dimensionless): 0.235460
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997357
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
04:05:20 (33994): called boinc_finish(0)

</stderr_txt>
]]>


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