𝕏

Task 54854678

Name HuVeMOp_20240626170549460391_ORdGradInc_k_24-Pueyo_APDR-conf_778_0
Workunit 26046133
Created 26 Jun 2024, 15:07:58 UTC
Sent 26 Jun 2024, 17:12:11 UTC
Report deadline 30 Jun 2024, 2:48:11 UTC
Received 26 Jun 2024, 21:11:15 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 229534
Run time 2 hours 14 min 31 sec
CPU time 2 hours 12 min 49 sec
Validate state Valid
Credit 59.01
Device peak FLOPS 4.00 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.83 MB
Peak swap size 6.39 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626170549460391_ORdGradInc_k_24-Pueyo_APDR-conf_778.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626170549460391_ORdGradInc_k_24-Pueyo_APDR-conf_778_0_r2009923270_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626170549460391_ORdGradInc_k_24-Pueyo_APDR-conf_778_0_r2009923270_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 99.871233
     * GNaL_b in INaL: 0.005893
     * Gto_b in Ito: 0.085661
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033258
     * GKs_b in IKs: 0.001840
     * GK1_b in IK1: 0.157156
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 65.562627
     * GKb_b in IKb: 0.003971
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032374
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 16558946, states[0] = 6.587880, states[40]= 0.004788
Saving checkpoint... 
Iteration: 33523524, states[0] = 19.831616, states[40]= 0.007213
Saving checkpoint... 
Iteration: 50555840, states[0] = 8.396195, states[40]= 0.004874
Saving checkpoint... 
Iteration: 67671930, states[0] = -94.565833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84724743, states[0] = -94.776248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 101719233, states[0] = -94.764368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 118819150, states[0] = -94.879271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 135729890, states[0] = -94.781003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 152611834, states[0] = -33.013511, states[40]= 0.000338
Saving checkpoint... 
Iteration: 169361147, states[0] = -94.900943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 186313937, states[0] = -94.874017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 203090764, states[0] = -12.874395, states[40]= 0.001812
Saving checkpoint... 
Iteration: 220114695, states[0] = -35.755278, states[40]= 0.000239
Saving checkpoint... 
Iteration: 237146027, states[0] = -70.368817, states[40]= 0.000001
Saving checkpoint... 
Iteration: 254004390, states[0] = 29.559318, states[40]= 0.166221
Saving checkpoint... 
Iteration: 270952932, states[0] = -94.927840, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626170549460391_ORdGradInc_k_24-Pueyo_APDR-conf_778.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626170549460391_ORdGradInc_k_24-Pueyo_APDR-conf_778_0_r2009923270_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626170549460391_ORdGradInc_k_24-Pueyo_APDR-conf_778_0_r2009923270_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 99.871233
     * GNaL_b in INaL: 0.005893
     * Gto_b in Ito: 0.085661
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033258
     * GKs_b in IKs: 0.001840
     * GK1_b in IK1: 0.157156
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 65.562627
     * GKb_b in IKb: 0.003971
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032374
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 270952932
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.927840 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 285848166, states[0] = -94.894266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 301236599, states[0] = -94.790508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 317914334, states[0] = -94.919055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 334281328, states[0] = -94.846325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 349262956, states[0] = -94.826420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 366415419, states[0] = -94.919306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 383499270, states[0] = -94.934760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 400541077, states[0] = 14.458079, states[40]= 0.005121
Saving checkpoint... 
Iteration: 417715760, states[0] = -94.754528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 434689104, states[0] = -94.698229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 451617917, states[0] = -38.920507, states[40]= 0.000154
Saving checkpoint... 
Iteration: 468392705, states[0] = -94.912465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 485459766, states[0] = -94.928902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 502360218, states[0] = -94.899851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 519149581, states[0] = -75.555988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 535835623, states[0] = -94.887316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 552872616, states[0] = -94.905083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 570077389, states[0] = -2.232780, states[40]= 0.003945
Saving checkpoint... 
Iteration: 587260294, states[0] = -94.823036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 604442999, states[0] = -94.925619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 621219167, states[0] = -94.760730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 638510744, states[0] = 22.512144, states[40]= 0.043406
Saving checkpoint... 
Iteration: 655779374, states[0] = -94.844143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 672946125, states[0] = -94.926204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 690265308, states[0] = -94.828928, states[40]= 0.000000
Saving checkpoint... 
Iteration: 706980705, states[0] = -94.932077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 724132813, states[0] = -54.599177, states[40]= 0.000013
Saving checkpoint... 
Iteration: 741208312, states[0] = -94.739743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 758276080, states[0] = -94.840705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 775335226, states[0] = -94.886913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 792412417, states[0] = -94.918179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 809729515, states[0] = -94.778715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 827052248, states[0] = 10.118215, states[40]= 0.004914
Saving checkpoint... 
Iteration: 844317533, states[0] = -94.875770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861670302, states[0] = -94.457748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 878921608, states[0] = -94.920535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 896109889, states[0] = -31.101848, states[40]= 0.000420
Saving checkpoint... 
Iteration: 913378790, states[0] = -94.907218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 930517812, states[0] = 21.263693, states[40]= 0.011555
Saving checkpoint... 
Iteration: 947179130, states[0] = -94.662175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 964174052, states[0] = -94.600270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 981499975, states[0] = -94.934406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 998808596, states[0] = -94.869271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1016134888, states[0] = -56.895251, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1032993914, states[0] = -94.933623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1050265507, states[0] = -94.828894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1067480613, states[0] = -94.931800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1084665805, states[0] = -93.894217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1101957381, states[0] = -94.928026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1119271218, states[0] = -94.835263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1136493783, states[0] = -94.933531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1153475454, states[0] = -94.930975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1170798935, states[0] = -94.861569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1187565561, states[0] = 4.285036, states[40]= 0.004689
Saving checkpoint... 
Iteration: 1204289415, states[0] = -94.853320, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626170549460391_ORdGradInc_k_24-Pueyo_APDR-conf_778.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626170549460391_ORdGradInc_k_24-Pueyo_APDR-conf_778_0_r2009923270_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626170549460391_ORdGradInc_k_24-Pueyo_APDR-conf_778_0_r2009923270_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 99.871233
     * GNaL_b in INaL: 0.005893
     * Gto_b in Ito: 0.085661
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033258
     * GKs_b in IKs: 0.001840
     * GK1_b in IK1: 0.157156
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 65.562627
     * GKb_b in IKb: 0.003971
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032374
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1204289415
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.853320 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1221590375, states[0] = -12.507006, states[40]= 0.001876
Saving checkpoint... 
Iteration: 1238662707, states[0] = -92.826726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1255998210, states[0] = -94.933993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1273358521, states[0] = -94.898515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1290522144, states[0] = 20.377713, states[40]= 0.007818
Saving checkpoint... 
Iteration: 1307764538, states[0] = -94.827577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1325023881, states[0] = 19.962789, states[40]= 0.007116
Saving checkpoint... 
Iteration: 1342365115, states[0] = -94.901391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1359695593, states[0] = -94.712466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1376863435, states[0] = -94.900638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1394187962, states[0] = -94.694683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1411201541, states[0] = -94.725275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1428413876, states[0] = -94.918111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1445761729, states[0] = -94.824143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1463040794, states[0] = 14.563247, states[40]= 0.005130
Saving checkpoint... 
Iteration: 1480413251, states[0] = -94.917903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497787703, states[0] = -94.851540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1515045656, states[0] = 9.867184, states[40]= 0.005715
Saving checkpoint... 
Iteration: 1532299596, states[0] = -95.079624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1549482206, states[0] = -95.199499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1566755286, states[0] = -94.971475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1583873481, states[0] = -95.043266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1601431137, states[0] = 16.192665, states[40]= 0.006731
Saving checkpoint... 
Iteration: 1618698975, states[0] = -95.105724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1635843716, states[0] = -95.177187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1652409369, states[0] = 23.690751, states[40]= 0.060393
Saving checkpoint... 
Iteration: 1669622788, states[0] = -68.947006, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1686875857, states[0] = -95.210957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1703998612, states[0] = -95.228316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1721154439, states[0] = 4.168423, states[40]= 0.005323
Saving checkpoint... 
Iteration: 1738397621, states[0] = -95.104727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1755579757, states[0] = -95.214345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1772725582, states[0] = 18.428653, states[40]= 0.007737
Saving checkpoint... 
Iteration: 1790024930, states[0] = -95.152664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1806963422, states[0] = -94.985799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1824169446, states[0] = -94.568696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1841403693, states[0] = -94.937769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1858688243, states[0] = -94.709097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1875897211, states[0] = -94.921198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1893083350, states[0] = -6.671437, states[40]= 0.003075
Saving checkpoint... 
Iteration: 1910150761, states[0] = -77.747716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1927416173, states[0] = -94.920164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1944593601, states[0] = -15.584424, states[40]= 0.001403
Saving checkpoint... 
Iteration: 1961879866, states[0] = -94.907474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1979083450, states[0] = -6.568630, states[40]= 0.003094
Saving checkpoint... 
Iteration: 1996280430, states[0] = -94.844399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2013498723, states[0] = -94.933586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2030749701, states[0] = -94.808331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2048032179, states[0] = 17.569217, states[40]= 0.005638
Saving checkpoint... 
Iteration: 2065081698, states[0] = -5.215546, states[40]= 0.003380
Saving checkpoint... 
Iteration: 2081900441, states[0] = -94.913703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2099088577, states[0] = -10.874377, states[40]= 0.002182
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.809410
 - CaMKt in component CaMK (millimolar): 0.007212
 - cass in component intracellular_ions (millimolar): 0.000075
 - nai in component intracellular_ions (millimolar): 6.756958
 - nass in component intracellular_ions (millimolar): 6.757019
 - ki in component intracellular_ions (millimolar): 145.215515
 - kss in component intracellular_ions (millimolar): 145.215495
 - cansr in component intracellular_ions (millimolar): 1.331065
 - cajsr in component intracellular_ions (millimolar): 1.293147
 - cai in component intracellular_ions (millimolar): 0.000076
 - m in component INa (dimensionless): 0.003652
 - hf in component INa (dimensionless): 0.878388
 - hs in component INa (dimensionless): 0.878383
 - j in component INa (dimensionless): 0.878352
 - hsp in component INa (dimensionless): 0.722796
 - jp in component INa (dimensionless): 0.878332
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.707958
 - hLp in component INaL (dimensionless): 0.450694
 - a in component Ito (dimensionless): 0.000627
 - iF in component Ito (dimensionless): 0.999868
 - iS in component Ito (dimensionless): 0.623196
 - ap in component Ito (dimensionless): 0.000320
 - iFp in component Ito (dimensionless): 0.999868
 - iSp in component Ito (dimensionless): 0.698532
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.937722
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999894
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001676
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.323897
 - xs1 in component IKs (dimensionless): 0.236312
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997361
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
13:32:25 (9480): called boinc_finish(0)

</stderr_txt>
]]>


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