𝕏

Task 54850866

Name HuVeMOp_20240624175735641681_ORdGradInc_k_24-BASE_MID-conf_393_3
Workunit 25874143
Created 26 Jun 2024, 14:36:44 UTC
Sent 26 Jun 2024, 16:30:52 UTC
Report deadline 29 Jun 2024, 16:30:52 UTC
Received 29 Jun 2024, 14:17:21 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 242076
Run time 4 hours 29 min 23 sec
CPU time 2 hours 53 min 44 sec
Validate state Valid
Credit 43.00
Device peak FLOPS 2.17 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64

Stderr output

<core_client_version>7.0.80</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624175735641681_ORdGradInc_k_24-BASE_MID-conf_393.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624175735641681_ORdGradInc_k_24-BASE_MID-conf_393_3_r679039785_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624175735641681_ORdGradInc_k_24-BASE_MID-conf_393_3_r679039785_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 14
     * GNa in INa: 105.756485
     * GNaL_b in INaL: 0.008042
     * Gto_b in Ito: 0.078350
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032172
     * GKs_b in IKs: 0.001773
     * GK1_b in IK1: 0.151266
     * Gncx_b in INaCa_i: 0.000954
     * Pnak_b in INaK: 66.745101
     * GKb_b in IKb: 0.003913
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037276
     * celltype in environment: 2.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 1199245, states[0] = -48.173543, states[40]= 0.000149
Saving checkpoint... 
Iteration: 1246013, states[0] = -86.445932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1921740, states[0] = -86.826754, states[40]= 0.000001
Saving checkpoint... 
Iteration: 6933484, states[0] = -86.817154, states[40]= 0.000001
Saving checkpoint... 
Iteration: 7880832, states[0] = -86.766064, states[40]= 0.000001
Saving checkpoint... 
Iteration: 15527793, states[0] = 33.572566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25100326, states[0] = 9.524375, states[40]= 0.000013
Saving checkpoint... 
Iteration: 31710410, states[0] = -81.245374, states[40]= 0.000001
Saving checkpoint... 
Iteration: 40036316, states[0] = 31.674331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 49926296, states[0] = -86.900071, states[40]= 0.000002
Saving checkpoint... 
Iteration: 58587802, states[0] = 13.135646, states[40]= 0.000008
Saving checkpoint... 
Iteration: 64464672, states[0] = -86.945424, states[40]= 0.000002
Saving checkpoint... 
Iteration: 69420702, states[0] = -86.921891, states[40]= 0.000002
Saving checkpoint... 
Iteration: 74095949, states[0] = 8.990515, states[40]= 0.000023
Saving checkpoint... 
Iteration: 80279058, states[0] = -86.634417, states[40]= 0.000001
Saving checkpoint... 
Iteration: 86722281, states[0] = -86.282448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 95372532, states[0] = -86.888041, states[40]= 0.000002
Saving checkpoint... 
Iteration: 104133147, states[0] = -15.084903, states[40]= 0.000213
Saving checkpoint... 
Iteration: 113578856, states[0] = 16.218293, states[40]= 0.000004
Saving checkpoint... 
Iteration: 124340928, states[0] = -86.843056, states[40]= 0.000002
Saving checkpoint... 
Iteration: 127550161, states[0] = 27.142555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133684352, states[0] = -61.930712, states[40]= 0.000027
Saving checkpoint... 
Iteration: 145424313, states[0] = -86.956158, states[40]= 0.000002
Saving checkpoint... 
Iteration: 153348657, states[0] = -86.861528, states[40]= 0.000002
Saving checkpoint... 
Iteration: 159426700, states[0] = -86.958779, states[40]= 0.000002
Saving checkpoint... 
Iteration: 169760731, states[0] = -86.569370, states[40]= 0.000001
Saving checkpoint... 
Iteration: 179869207, states[0] = -86.896381, states[40]= 0.000002
Saving checkpoint... 
Iteration: 188445614, states[0] = -86.972078, states[40]= 0.000002
Saving checkpoint... 
Iteration: 196334590, states[0] = -86.833025, states[40]= 0.000002
Saving checkpoint... 
Iteration: 200579829, states[0] = 15.603953, states[40]= 0.000005
Saving checkpoint... 
Iteration: 210404719, states[0] = -86.938951, states[40]= 0.000002
Saving checkpoint... 
Iteration: 217030071, states[0] = 31.759454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226223213, states[0] = -86.311544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 232034042, states[0] = 31.157241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 238530680, states[0] = 31.679391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 248569513, states[0] = 19.964055, states[40]= 0.000001
Saving checkpoint... 
Iteration: 255918999, states[0] = -86.949955, states[40]= 0.000002
Saving checkpoint... 
Iteration: 263226395, states[0] = -86.336743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 272136385, states[0] = -18.726087, states[40]= 0.000268
Saving checkpoint... 
Iteration: 282055470, states[0] = 25.285783, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624175735641681_ORdGradInc_k_24-BASE_MID-conf_393.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624175735641681_ORdGradInc_k_24-BASE_MID-conf_393_3_r679039785_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624175735641681_ORdGradInc_k_24-BASE_MID-conf_393_3_r679039785_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 14
     * GNa in INa: 105.756485
     * GNaL_b in INaL: 0.008042
     * Gto_b in Ito: 0.078350
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032172
     * GKs_b in IKs: 0.001773
     * GK1_b in IK1: 0.151266
     * Gncx_b in INaCa_i: 0.000954
     * Pnak_b in INaK: 66.745101
     * GKb_b in IKb: 0.003913
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037276
     * celltype in environment: 2.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 282055470
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 25.285783 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 296295822, states[0] = -86.719115, states[40]= 0.000001
Saving checkpoint... 
Iteration: 309437678, states[0] = -86.961311, states[40]= 0.000002
Saving checkpoint... 
Iteration: 322720109, states[0] = -86.277083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 330829259, states[0] = -86.814205, states[40]= 0.000002
Saving checkpoint... 
Iteration: 337334450, states[0] = -86.825712, states[40]= 0.000002
Saving checkpoint... 
Iteration: 343945420, states[0] = -86.964444, states[40]= 0.000002
Saving checkpoint... 
Iteration: 354671811, states[0] = -48.830687, states[40]= 0.000152
Saving checkpoint... 
Iteration: 369766641, states[0] = -86.591092, states[40]= 0.000001
Saving checkpoint... 
Iteration: 385178884, states[0] = -56.311558, states[40]= 0.000060
Saving checkpoint... 
Iteration: 399307467, states[0] = -86.751541, states[40]= 0.000002
Saving checkpoint... 
Iteration: 414031105, states[0] = 31.622860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 429281221, states[0] = -86.655040, states[40]= 0.000001
Saving checkpoint... 
Iteration: 445383565, states[0] = -86.902592, states[40]= 0.000002
Saving checkpoint... 
Iteration: 462941756, states[0] = -86.955345, states[40]= 0.000002
Saving checkpoint... 
Iteration: 477798136, states[0] = -86.716737, states[40]= 0.000001
Saving checkpoint... 
Iteration: 491336547, states[0] = -86.821493, states[40]= 0.000002
Saving checkpoint... 
Iteration: 503131434, states[0] = -14.667303, states[40]= 0.000214
Saving checkpoint... 
Iteration: 516551947, states[0] = 26.480845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 530915893, states[0] = -86.931867, states[40]= 0.000002
Saving checkpoint... 
Iteration: 547194551, states[0] = -77.214332, states[40]= 0.000003
Saving checkpoint... 
Iteration: 562843618, states[0] = -86.832123, states[40]= 0.000002
Saving checkpoint... 
Iteration: 578608091, states[0] = 1.869840, states[40]= 0.000093
Saving checkpoint... 
Iteration: 592405739, states[0] = -86.918947, states[40]= 0.000002
Saving checkpoint... 
Iteration: 607262028, states[0] = -86.553336, states[40]= 0.000001
Saving checkpoint... 
Iteration: 622286371, states[0] = -86.664992, states[40]= 0.000001
Saving checkpoint... 
Iteration: 637265895, states[0] = -86.571808, states[40]= 0.000001
Saving checkpoint... 
Iteration: 654293800, states[0] = -86.691310, states[40]= 0.000001
Saving checkpoint... 
Iteration: 669452130, states[0] = -86.950075, states[40]= 0.000002
Saving checkpoint... 
Iteration: 686564087, states[0] = 22.123340, states[40]= 0.000001
Saving checkpoint... 
Iteration: 703804437, states[0] = -86.724597, states[40]= 0.000002
Saving checkpoint... 
Iteration: 723665852, states[0] = -42.914937, states[40]= 0.000288
Saving checkpoint... 
Iteration: 743663148, states[0] = -40.378040, states[40]= 0.000366
Saving checkpoint... 
Iteration: 760958442, states[0] = -86.948461, states[40]= 0.000002
Saving checkpoint... 
Iteration: 779870546, states[0] = -86.865911, states[40]= 0.000002
Saving checkpoint... 
Iteration: 798314395, states[0] = -86.749036, states[40]= 0.000002
Saving checkpoint... 
Iteration: 816876317, states[0] = -86.871961, states[40]= 0.000002
Saving checkpoint... 
Iteration: 835697317, states[0] = -80.791551, states[40]= 0.000002
Saving checkpoint... 
Iteration: 853303708, states[0] = -86.713665, states[40]= 0.000002
Saving checkpoint... 
Iteration: 871277638, states[0] = -86.614057, states[40]= 0.000001
Saving checkpoint... 
Iteration: 890335650, states[0] = -86.796777, states[40]= 0.000002
Saving checkpoint... 
Iteration: 909063871, states[0] = 22.211564, states[40]= 0.000001
Saving checkpoint... 
Iteration: 928127042, states[0] = -11.002521, states[40]= 0.000208
Saving checkpoint... 
Iteration: 948047376, states[0] = 27.925209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 967001289, states[0] = 34.637503, states[40]= 2.203373
Saving checkpoint... 
Iteration: 986388364, states[0] = -86.877777, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1006117818, states[0] = -4.036963, states[40]= 0.000173
Saving checkpoint... 
Iteration: 1024719391, states[0] = -86.227836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1043952413, states[0] = -86.929061, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1063095760, states[0] = 8.241141, states[40]= 0.000030
Saving checkpoint... 
Iteration: 1082143716, states[0] = -24.326882, states[40]= 0.000506
Saving checkpoint... 
Iteration: 1101725962, states[0] = -86.283952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1120583685, states[0] = 13.890721, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1139492192, states[0] = -86.942242, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1158587835, states[0] = 11.997681, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1178630096, states[0] = -13.501889, states[40]= 0.000209
Saving checkpoint... 
Iteration: 1196365648, states[0] = -86.834847, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1214050040, states[0] = 27.111183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232881911, states[0] = -86.855788, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1252726699, states[0] = -86.281135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1272811768, states[0] = -86.714321, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1292373207, states[0] = -86.840612, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1312542866, states[0] = 29.206339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1331848341, states[0] = -86.797487, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1350966319, states[0] = -86.919216, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1370492778, states[0] = -86.929425, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1388764162, states[0] = -86.519295, states[40]= 0.000001


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624175735641681_ORdGradInc_k_24-BASE_MID-conf_393.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624175735641681_ORdGradInc_k_24-BASE_MID-conf_393_3_r679039785_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624175735641681_ORdGradInc_k_24-BASE_MID-conf_393_3_r679039785_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 14
     * GNa in INa: 105.756485
     * GNaL_b in INaL: 0.008042
     * Gto_b in Ito: 0.078350
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032172
     * GKs_b in IKs: 0.001773
     * GK1_b in IK1: 0.151266
     * Gncx_b in INaCa_i: 0.000954
     * Pnak_b in INaK: 66.745101
     * GKb_b in IKb: 0.003913
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037276
     * celltype in environment: 2.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1388764162
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -86.519295 (After loading)
 - states[40]: 0.000001 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1399468924, states[0] = -86.917736, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1410935903, states[0] = -86.897751, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1423760645, states[0] = -86.498494, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1440112285, states[0] = -0.498068, states[40]= 0.000125
Saving checkpoint... 
Iteration: 1464690087, states[0] = -70.300716, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1484177843, states[0] = -55.027458, states[40]= 0.000069
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.800520
 - CaMKt in component CaMK (millimolar): 0.025468
 - cass in component intracellular_ions (millimolar): 0.000094
 - nai in component intracellular_ions (millimolar): 8.133220
 - nass in component intracellular_ions (millimolar): 8.133373
 - ki in component intracellular_ions (millimolar): 143.246775
 - kss in component intracellular_ions (millimolar): 143.246737
 - cansr in component intracellular_ions (millimolar): 2.074289
 - cajsr in component intracellular_ions (millimolar): 2.010439
 - cai in component intracellular_ions (millimolar): 0.000097
 - m in component INa (dimensionless): 0.008184
 - hf in component INa (dimensionless): 0.659551
 - hs in component INa (dimensionless): 0.659519
 - j in component INa (dimensionless): 0.659333
 - hsp in component INa (dimensionless): 0.411467
 - jp in component INa (dimensionless): 0.659200
 - mL in component INaL (dimensionless): 0.000231
 - hL in component INaL (dimensionless): 0.454780
 - hLp in component INaL (dimensionless): 0.220191
 - a in component Ito (dimensionless): 0.001076
 - iF in component Ito (dimensionless): 0.999462
 - iS in component Ito (dimensionless): 0.530332
 - ap in component Ito (dimensionless): 0.000549
 - iFp in component Ito (dimensionless): 0.999462
 - iSp in component Ito (dimensionless): 0.573402
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.874651
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999589
 - jca in component ICaL (dimensionless): 0.999936
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003986
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.513427
 - xs1 in component IKs (dimensionless): 0.337228
 - xs2 in component IKs (dimensionless): 0.000218
 - xk1 in component IK1 (dimensionless): 0.997031
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000002
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000002
15:17:10 (19324): called boinc_finish(0)

</stderr_txt>
]]>


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