𝕏

Task 54845249

Name HuVeMOp_20240626145050251776_ORdGradInc_k_24-BASE_MID-conf_43_0
Workunit 26041652
Created 26 Jun 2024, 12:52:01 UTC
Sent 26 Jun 2024, 15:40:24 UTC
Report deadline 29 Jun 2024, 15:40:24 UTC
Received 26 Jun 2024, 20:13:47 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241398
Run time 2 hours 52 min 54 sec
CPU time 2 hours 52 min 43 sec
Validate state Invalid
Credit 0.00
Device peak FLOPS 1.78 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.68 MB
Peak swap size 3.88 MB
Peak disk usage 0.34 MB

Stderr output

<core_client_version>7.18.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626145050251776_ORdGradInc_k_24-BASE_MID-conf_43.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626145050251776_ORdGradInc_k_24-BASE_MID-conf_43_0_r887502339_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626145050251776_ORdGradInc_k_24-BASE_MID-conf_43_0_r887502339_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 14
     * GNa in INa: 118.174143
     * GNaL_b in INaL: 0.007657
     * Gto_b in Ito: 0.082140
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.034140
     * GKs_b in IKs: 0.001936
     * GK1_b in IK1: 0.160205
     * Gncx_b in INaCa_i: 0.000953
     * Pnak_b in INaK: 63.682062
     * GKb_b in IKb: 0.003770
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.038102
     * celltype in environment: 2.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 9619082, states[0] = 2.826606, states[40]= 0.000042
Saving checkpoint... 
Iteration: 19113279, states[0] = 3.687213, states[40]= 0.000035
Saving checkpoint... 
Iteration: 28774304, states[0] = -86.464339, states[40]= 0.000001
Saving checkpoint... 
Iteration: 38354855, states[0] = -86.712909, states[40]= 0.000002
Saving checkpoint... 
Iteration: 48017617, states[0] = 31.663887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 57660048, states[0] = -37.808346, states[40]= 0.000362
Saving checkpoint... 
Iteration: 67215021, states[0] = -86.159172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 76748030, states[0] = -86.414591, states[40]= 0.000001
Saving checkpoint... 
Iteration: 86307778, states[0] = -86.676615, states[40]= 0.000002
Saving checkpoint... 
Iteration: 95945171, states[0] = -86.879611, states[40]= 0.000002
Saving checkpoint... 
Iteration: 105550838, states[0] = 26.490226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 115152714, states[0] = -35.681027, states[40]= 0.000470
Saving checkpoint... 
Iteration: 124701731, states[0] = -85.911950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 134273169, states[0] = -86.571157, states[40]= 0.000001
Saving checkpoint... 
Iteration: 143954870, states[0] = -86.897631, states[40]= 0.000002
Saving checkpoint... 
Iteration: 153472020, states[0] = -86.906498, states[40]= 0.000002
Saving checkpoint... 
Iteration: 163024607, states[0] = 31.642653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 172507599, states[0] = 25.556047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 182074561, states[0] = 17.141251, states[40]= 0.000004
Saving checkpoint... 
Iteration: 191623813, states[0] = -12.002653, states[40]= 0.000201
Saving checkpoint... 
Iteration: 201197079, states[0] = -85.448952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 210764596, states[0] = -86.533347, states[40]= 0.000001
Saving checkpoint... 
Iteration: 220416969, states[0] = -86.872659, states[40]= 0.000002
Saving checkpoint... 
Iteration: 229928942, states[0] = -86.881301, states[40]= 0.000002
Saving checkpoint... 
Iteration: 239471325, states[0] = -86.904595, states[40]= 0.000002
Saving checkpoint... 
Iteration: 248968158, states[0] = -86.902711, states[40]= 0.000002
Saving checkpoint... 
Iteration: 258581997, states[0] = 13.746279, states[40]= 0.000010
Saving checkpoint... 
Iteration: 267973484, states[0] = -86.903981, states[40]= 0.000002
Saving checkpoint... 
Iteration: 277595597, states[0] = 7.041293, states[40]= 0.000042
Saving checkpoint... 
Iteration: 287117602, states[0] = -6.827160, states[40]= 0.000196
Saving checkpoint... 
Iteration: 296763886, states[0] = -86.525297, states[40]= 0.000001
Saving checkpoint... 
Iteration: 306258730, states[0] = -86.498558, states[40]= 0.000001
Saving checkpoint... 
Iteration: 315696282, states[0] = -85.281502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 325199615, states[0] = -85.805106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 334777938, states[0] = -86.586423, states[40]= 0.000001
Saving checkpoint... 
Iteration: 344226995, states[0] = -86.294212, states[40]= 0.000001
Saving checkpoint... 
Iteration: 353620039, states[0] = -8.824613, states[40]= 0.000202
Saving checkpoint... 
Iteration: 363159278, states[0] = -42.958216, states[40]= 0.000267
Saving checkpoint... 
Iteration: 372613438, states[0] = -3.662639, states[40]= 0.000171
Saving checkpoint... 
Iteration: 382229433, states[0] = -86.310089, states[40]= 0.000001
Saving checkpoint... 
Iteration: 391728078, states[0] = -86.299406, states[40]= 0.000001
Saving checkpoint... 
Iteration: 401359749, states[0] = -86.796983, states[40]= 0.000002
Saving checkpoint... 
Iteration: 410940975, states[0] = -86.878731, states[40]= 0.000002
Saving checkpoint... 
Iteration: 420699293, states[0] = -85.766202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 430446817, states[0] = -86.881041, states[40]= 0.000002
Saving checkpoint... 
Iteration: 440080010, states[0] = 14.668600, states[40]= 0.000008
Saving checkpoint... 
Iteration: 449641664, states[0] = -27.148539, states[40]= 0.000539
Saving checkpoint... 
Iteration: 459309345, states[0] = -86.686600, states[40]= 0.000002
Saving checkpoint... 
Iteration: 468959037, states[0] = -86.885305, states[40]= 0.000002
Saving checkpoint... 
Iteration: 478466542, states[0] = -86.888335, states[40]= 0.000002
Saving checkpoint... 
Iteration: 488047047, states[0] = 27.474021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 497570638, states[0] = 18.809101, states[40]= 0.000002
Saving checkpoint... 
Iteration: 507121670, states[0] = -10.200346, states[40]= 0.000202
Saving checkpoint... 
Iteration: 516588626, states[0] = 10.577262, states[40]= 0.000021
Saving checkpoint... 
Iteration: 526172352, states[0] = -56.920405, states[40]= 0.000053
Saving checkpoint... 
Iteration: 535724526, states[0] = -86.263207, states[40]= 0.000001
Saving checkpoint... 
Iteration: 545422116, states[0] = -86.857635, states[40]= 0.000002
Saving checkpoint... 
Iteration: 555172203, states[0] = -56.743225, states[40]= 0.000054
Saving checkpoint... 
Iteration: 564759253, states[0] = -86.485319, states[40]= 0.000001
Saving checkpoint... 
Iteration: 574446852, states[0] = -86.872385, states[40]= 0.000002
Saving checkpoint... 
Iteration: 584012012, states[0] = 29.085789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 593573632, states[0] = 17.526767, states[40]= 0.000003
Saving checkpoint... 
Iteration: 603075910, states[0] = 16.525790, states[40]= 0.000005
Saving checkpoint... 
Iteration: 612673023, states[0] = -57.691383, states[40]= 0.000048
Saving checkpoint... 
Iteration: 622221153, states[0] = -86.230897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 631839642, states[0] = -86.747781, states[40]= 0.000002
Saving checkpoint... 
Iteration: 641487707, states[0] = -86.887177, states[40]= 0.000002
Saving checkpoint... 
Iteration: 651200967, states[0] = -85.885194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 660732621, states[0] = -86.315870, states[40]= 0.000001
Saving checkpoint... 
Iteration: 670233109, states[0] = -86.318754, states[40]= 0.000001
Saving checkpoint... 
Iteration: 679792335, states[0] = -86.619851, states[40]= 0.000002
Saving checkpoint... 
Iteration: 689394640, states[0] = -86.824276, states[40]= 0.000002
Saving checkpoint... 
Iteration: 698923501, states[0] = -86.849421, states[40]= 0.000002
Saving checkpoint... 
Iteration: 708495739, states[0] = -86.885867, states[40]= 0.000002
Saving checkpoint... 
Iteration: 718098575, states[0] = 5.470350, states[40]= 0.000056
Saving checkpoint... 
Iteration: 727625975, states[0] = -13.951235, states[40]= 0.000200
Saving checkpoint... 
Iteration: 737340381, states[0] = -86.742794, states[40]= 0.000002
Saving checkpoint... 
Iteration: 747033005, states[0] = 30.804567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 756711487, states[0] = -86.136037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 766291817, states[0] = -86.612771, states[40]= 0.000002
Saving checkpoint... 
Iteration: 775757505, states[0] = -86.463091, states[40]= 0.000001
Saving checkpoint... 
Iteration: 785186055, states[0] = -75.922479, states[40]= 0.000004
Saving checkpoint... 
Iteration: 794665447, states[0] = -49.252202, states[40]= 0.000136
Saving checkpoint... 
Iteration: 804430465, states[0] = -86.848122, states[40]= 0.000002
Saving checkpoint... 
Iteration: 814072022, states[0] = 18.227493, states[40]= 0.000003
Saving checkpoint... 
Iteration: 823687281, states[0] = -77.775721, states[40]= 0.000003
Saving checkpoint... 
Iteration: 833241396, states[0] = -86.364771, states[40]= 0.000001
Saving checkpoint... 
Iteration: 842720632, states[0] = -86.212810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 852454380, states[0] = -86.859810, states[40]= 0.000002
Saving checkpoint... 
Iteration: 862144893, states[0] = -29.790448, states[40]= 0.000574
Saving checkpoint... 
Iteration: 871784981, states[0] = -86.581357, states[40]= 0.000002
Saving checkpoint... 
Iteration: 880098779, states[0] = 5.365965, states[40]= 0.000057
Saving checkpoint... 
Iteration: 888867390, states[0] = -86.778834, states[40]= 0.000002
Saving checkpoint... 
Iteration: 898432495, states[0] = -86.843864, states[40]= 0.000002
Saving checkpoint... 
Iteration: 908027978, states[0] = 31.446208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 917552533, states[0] = 25.741696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 927383370, states[0] = -86.797335, states[40]= 0.000002
Saving checkpoint... 
Iteration: 937044158, states[0] = 28.315534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 946581001, states[0] = 14.224550, states[40]= 0.000009
Saving checkpoint... 
Iteration: 956169112, states[0] = -53.197699, states[40]= 0.000084
Saving checkpoint... 
Iteration: 965745093, states[0] = -86.379930, states[40]= 0.000001
Saving checkpoint... 
Iteration: 975339258, states[0] = -86.726138, states[40]= 0.000002
Saving checkpoint... 
Iteration: 985025965, states[0] = 31.587966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 994565116, states[0] = 21.094137, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1004210100, states[0] = -86.105024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1013900674, states[0] = -86.810760, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1023550716, states[0] = 26.343608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1033068146, states[0] = 19.863656, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1042617538, states[0] = -6.726371, states[40]= 0.000193
Saving checkpoint... 
Iteration: 1052294516, states[0] = -86.604539, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1061987823, states[0] = -86.861919, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1071660149, states[0] = -43.752906, states[40]= 0.000244
Saving checkpoint... 
Iteration: 1081274496, states[0] = -86.525959, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1090918138, states[0] = -86.821617, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1100562987, states[0] = 21.937989, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1110136275, states[0] = -22.719160, states[40]= 0.000364
Saving checkpoint... 
Iteration: 1119722748, states[0] = -86.212547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1129309252, states[0] = -86.645452, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1138732426, states[0] = -86.284623, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1148285182, states[0] = -86.565163, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1157925052, states[0] = -86.822929, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1167400224, states[0] = -86.801093, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1177129228, states[0] = -16.774089, states[40]= 0.000211
Saving checkpoint... 
Iteration: 1186900840, states[0] = -86.800511, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1196581295, states[0] = 14.094868, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1206265069, states[0] = -86.475003, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1215917870, states[0] = -86.813870, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1225523978, states[0] = 31.652379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1235210198, states[0] = -86.091485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1244905713, states[0] = -86.801619, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1254590844, states[0] = 9.500853, states[40]= 0.000026
Saving checkpoint... 
Iteration: 1264250896, states[0] = -86.396139, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1273880321, states[0] = -86.772684, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1283600260, states[0] = 4.571838, states[40]= 0.000064
Saving checkpoint... 
Iteration: 1293231189, states[0] = -86.266084, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1303036010, states[0] = 30.274970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1312695776, states[0] = -85.035244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1322403300, states[0] = -86.794702, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1332054711, states[0] = 25.006829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1341830397, states[0] = -86.685399, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1351523073, states[0] = 31.652194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1361146751, states[0] = -31.324288, states[40]= 0.000564
Saving checkpoint... 
Iteration: 1370847414, states[0] = -86.717545, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1380351551, states[0] = -86.724239, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1389766335, states[0] = -86.469793, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1399295062, states[0] = -86.585140, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1409121729, states[0] = -10.178546, states[40]= 0.000199
Saving checkpoint... 
Iteration: 1418680134, states[0] = -66.694181, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1428262730, states[0] = -86.449788, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1437800394, states[0] = -86.600182, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1447362242, states[0] = -86.737462, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1457063458, states[0] = 21.762129, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1466661998, states[0] = -45.580664, states[40]= 0.000201
Saving checkpoint... 
Iteration: 1476135511, states[0] = -22.064901, states[40]= 0.000336
Saving checkpoint... 
Iteration: 1485681561, states[0] = -68.758641, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1495235723, states[0] = -86.285636, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.715534
 - CaMKt in component CaMK (millimolar): 0.026262
 - cass in component intracellular_ions (millimolar): 0.000095
 - nai in component intracellular_ions (millimolar): 8.359327
 - nass in component intracellular_ions (millimolar): 8.359485
 - ki in component intracellular_ions (millimolar): 142.980887
 - kss in component intracellular_ions (millimolar): 142.980848
 - cansr in component intracellular_ions (millimolar): 2.137155
 - cajsr in component intracellular_ions (millimolar): 2.077695
 - cai in component intracellular_ions (millimolar): 0.000099
 - m in component INa (dimensionless): 0.008254
 - hf in component INa (dimensionless): 0.656408
 - hs in component INa (dimensionless): 0.656378
 - j in component INa (dimensionless): 0.656205
 - hsp in component INa (dimensionless): 0.408098
 - jp in component INa (dimensionless): 0.656081
 - mL in component INaL (dimensionless): 0.000235
 - hL in component INaL (dimensionless): 0.453819
 - hLp in component INaL (dimensionless): 0.221584
 - a in component Ito (dimensionless): 0.001083
 - iF in component Ito (dimensionless): 0.999454
 - iS in component Ito (dimensionless): 0.537394
 - ap in component Ito (dimensionless): 0.000552
 - iFp in component Ito (dimensionless): 0.999454
 - iSp in component Ito (dimensionless): 0.581129
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.880175
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999643
 - jca in component ICaL (dimensionless): 0.999945
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004262
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.506205
 - xs1 in component IKs (dimensionless): 0.328277
 - xs2 in component IKs (dimensionless): 0.000220
 - xk1 in component IK1 (dimensionless): 0.997052
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000002
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000002
19:44:19 (5041): called boinc_finish(0)

</stderr_txt>
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