𝕏

Task 54844479

Name HuVeMOp_20240626145050251776_ORdGradInc_k_24-Drouin_ENDO_2000-conf_327_0
Workunit 26041268
Created 26 Jun 2024, 12:51:35 UTC
Sent 26 Jun 2024, 15:29:41 UTC
Report deadline 29 Jun 2024, 15:29:41 UTC
Received 27 Jun 2024, 21:50:14 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 239842
Run time 1 hours 3 min 57 sec
CPU time 54 min 36 sec
Validate state Valid
Credit 40.53
Device peak FLOPS 6.87 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.47 MB
Peak swap size 3.69 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.20.5</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626145050251776_ORdGradInc_k_24-Drouin_ENDO_2000-conf_327.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626145050251776_ORdGradInc_k_24-Drouin_ENDO_2000-conf_327_0_r1012232263_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626145050251776_ORdGradInc_k_24-Drouin_ENDO_2000-conf_327_0_r1012232263_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 123.503726
     * GNaL_b in INaL: 0.009075
     * Gto_b in Ito: 0.089603
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032712
     * GKs_b in IKs: 0.001931
     * GK1_b in IK1: 0.149751
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 68.395046
     * GKb_b in IKb: 0.003788
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.038279
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 8320288, states[0] = -93.922415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 16884479, states[0] = -94.037675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25073149, states[0] = 16.610475, states[40]= 0.001994
Saving checkpoint... 
Iteration: 33376452, states[0] = -93.874021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 41734602, states[0] = -94.002714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 50010968, states[0] = 31.267301, states[40]= 0.042794
Saving checkpoint... 
Iteration: 58511234, states[0] = -93.976698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67017737, states[0] = 32.106584, states[40]= 0.004182
Saving checkpoint... 
Iteration: 75351370, states[0] = -93.830867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84382201, states[0] = -93.881328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 92453900, states[0] = -93.951811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 101028494, states[0] = 30.907796, states[40]= 0.000245
Saving checkpoint... 
Iteration: 109577128, states[0] = -93.999065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 117565537, states[0] = -93.997233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 126101259, states[0] = 3.568855, states[40]= 0.004115
Saving checkpoint... 
Iteration: 134561376, states[0] = -93.996875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 142439047, states[0] = -93.943264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 150618458, states[0] = -94.005766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 159181580, states[0] = -57.867088, states[40]= 0.000080
Saving checkpoint... 
Iteration: 167545507, states[0] = -93.993606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 176087258, states[0] = 10.428501, states[40]= 0.002908
Saving checkpoint... 
Iteration: 184526030, states[0] = -93.988146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 192700181, states[0] = -94.010096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 200795094, states[0] = -94.008580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 209473372, states[0] = -93.965981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 217575922, states[0] = -94.000166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226013760, states[0] = 31.783942, states[40]= 0.016395
Saving checkpoint... 
Iteration: 234948570, states[0] = -94.000656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 243321679, states[0] = -93.769996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 251869108, states[0] = -94.005094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260400479, states[0] = -93.907142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 268669308, states[0] = -94.009174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 276975081, states[0] = -93.998916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 285917801, states[0] = -94.002267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 294285224, states[0] = -93.657157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 302546209, states[0] = -93.993526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311530991, states[0] = -93.989307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 319596886, states[0] = -94.003055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 328028101, states[0] = 30.967974, states[40]= 0.000255
Saving checkpoint... 
Iteration: 336484979, states[0] = -93.971483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 344691159, states[0] = -94.009448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 352897125, states[0] = -94.003146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 361528188, states[0] = -93.988235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 369830166, states[0] = -94.006507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 377864244, states[0] = -94.004806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 386193450, states[0] = -68.772646, states[40]= 0.000013
Saving checkpoint... 
Iteration: 394633748, states[0] = -94.006602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 402749977, states[0] = -94.009073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 411226326, states[0] = -93.260003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 419383541, states[0] = -93.885475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 427388406, states[0] = -93.891832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 435680747, states[0] = -94.008803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 443701003, states[0] = -94.009141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 452346054, states[0] = -93.823850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 460728135, states[0] = -94.009099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 468747123, states[0] = -94.008825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 477162352, states[0] = -41.567420, states[40]= 0.000848
Saving checkpoint... 
Iteration: 486065945, states[0] = 19.151699, states[40]= 0.001156
Saving checkpoint... 
Iteration: 493808298, states[0] = -94.006883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 501979756, states[0] = -93.997626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 510560289, states[0] = -93.995864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 518107439, states[0] = -0.011911, states[40]= 0.004294
Saving checkpoint... 
Iteration: 526620260, states[0] = -94.004823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 534946842, states[0] = -93.999447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 543178058, states[0] = -54.844555, states[40]= 0.000130
Saving checkpoint... 
Iteration: 551288904, states[0] = -93.669340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 559712323, states[0] = -94.008687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 567812156, states[0] = -94.006390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 576259569, states[0] = -93.548664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 584609329, states[0] = -94.003406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 593134401, states[0] = -20.448206, states[40]= 0.002107
Saving checkpoint... 
Iteration: 601171006, states[0] = -48.781549, states[40]= 0.000324
Saving checkpoint... 
Iteration: 609476287, states[0] = -93.965837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 617828334, states[0] = -94.005463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 626185252, states[0] = -61.108172, states[40]= 0.000046
Saving checkpoint... 
Iteration: 634364568, states[0] = -93.856313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 642616526, states[0] = -94.003923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 651093607, states[0] = 7.463339, states[40]= 0.003516
Saving checkpoint... 
Iteration: 658998351, states[0] = -93.995787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 666861483, states[0] = -94.003635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 675151331, states[0] = -33.031626, states[40]= 0.002109
Saving checkpoint... 
Iteration: 683441243, states[0] = -93.943219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 691546099, states[0] = -93.991736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 700152703, states[0] = -34.062507, states[40]= 0.001930
Saving checkpoint... 
Iteration: 708572477, states[0] = -93.997395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 716226850, states[0] = -93.276234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 724573749, states[0] = -93.997556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 732954681, states[0] = -93.998079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 741156613, states[0] = -37.041806, states[40]= 0.001436
Saving checkpoint... 
Iteration: 749182147, states[0] = -58.383379, states[40]= 0.000073
Saving checkpoint... 
Iteration: 757741189, states[0] = -94.007606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 765726320, states[0] = -94.007724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 773861906, states[0] = -94.003126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 782136057, states[0] = -21.714207, states[40]= 0.002278
Saving checkpoint... 
Iteration: 790378651, states[0] = -93.877026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 798831901, states[0] = -94.004477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 806996890, states[0] = -93.995202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 815658419, states[0] = -94.006239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 823356825, states[0] = -93.842285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 831288990, states[0] = -93.668349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 839637553, states[0] = -94.004867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 848163415, states[0] = -42.427579, states[40]= 0.000761
Saving checkpoint... 
Iteration: 856270777, states[0] = -93.597233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 864704167, states[0] = -94.007257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 872936777, states[0] = -93.998503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 881001098, states[0] = 51.581887, states[40]= 0.330397
Saving checkpoint... 
Iteration: 889151033, states[0] = -32.807707, states[40]= 0.002148
Saving checkpoint... 
Iteration: 897614885, states[0] = -94.002592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 905610394, states[0] = -94.002067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 913899021, states[0] = -94.000489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 922460133, states[0] = -93.955111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 930238826, states[0] = -93.439378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 938538417, states[0] = -93.988588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 946589313, states[0] = -93.999127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 954776414, states[0] = -94.005913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 963076414, states[0] = 15.054825, states[40]= 0.001906
Saving checkpoint... 
Iteration: 971185344, states[0] = -61.187116, states[40]= 0.000046
Saving checkpoint... 
Iteration: 979339601, states[0] = -93.808246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 987526455, states[0] = -93.984850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 995777979, states[0] = -94.005679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1003564235, states[0] = -93.994448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1011889837, states[0] = -94.000553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1020033323, states[0] = 29.820422, states[40]= 0.000208
Saving checkpoint... 
Iteration: 1028245912, states[0] = -93.479370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1036512911, states[0] = -93.980056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1044626643, states[0] = -94.003058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1052150839, states[0] = -32.661996, states[40]= 0.002173
Saving checkpoint... 
Iteration: 1060225290, states[0] = -93.214844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1068664405, states[0] = -94.005361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1076561606, states[0] = -93.993570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1084518451, states[0] = -93.981788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1093018384, states[0] = 32.075045, states[40]= 0.003366
Saving checkpoint... 
Iteration: 1100906605, states[0] = -93.999211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1109296373, states[0] = -93.692411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1117483543, states[0] = -93.967228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1126006137, states[0] = 30.935716, states[40]= 0.229333
Saving checkpoint... 
Iteration: 1134349996, states[0] = -93.828349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1142711304, states[0] = -94.006034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1150821078, states[0] = -94.003360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1159359814, states[0] = -93.845949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167576656, states[0] = -93.996062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1175675794, states[0] = -94.005294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1184182908, states[0] = -59.043698, states[40]= 0.000065
Saving checkpoint... 
Iteration: 1192306028, states[0] = -93.722420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1200593122, states[0] = -93.998530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1209252972, states[0] = -93.514210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1217046219, states[0] = 26.095158, states[40]= 0.000392
Saving checkpoint... 
Iteration: 1225447800, states[0] = -93.945535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1234076697, states[0] = 14.939988, states[40]= 0.001929
Saving checkpoint... 
Iteration: 1241825389, states[0] = -94.002756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1250041130, states[0] = 27.678798, states[40]= 0.000294
Saving checkpoint... 
Iteration: 1258690151, states[0] = -94.005276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1266774383, states[0] = -94.004554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1275009158, states[0] = 30.782724, states[40]= 0.080711
Saving checkpoint... 
Iteration: 1283565075, states[0] = -93.993345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1291914853, states[0] = -93.997871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1300143959, states[0] = -27.571844, states[40]= 0.002786
Saving checkpoint... 
Iteration: 1308911374, states[0] = -93.997993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1316841352, states[0] = -94.001677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1325246703, states[0] = -93.482113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1333952725, states[0] = -93.995460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1342249684, states[0] = -93.497271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1350517563, states[0] = -93.980272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1358768284, states[0] = -94.004307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1367097029, states[0] = 5.767401, states[40]= 0.003813
Saving checkpoint... 
Iteration: 1375492400, states[0] = -93.970218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1384061893, states[0] = 20.661369, states[40]= 0.000936
Saving checkpoint... 
Iteration: 1392268589, states[0] = -93.585369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1400832823, states[0] = -94.001696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1409436250, states[0] = -93.936044, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1417863513, states[0] = -94.000113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1426518978, states[0] = -93.980411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1435120697, states[0] = -9.409270, states[40]= 0.002931
Saving checkpoint... 
Iteration: 1443123063, states[0] = -11.317662, states[40]= 0.002546
Saving checkpoint... 
Iteration: 1451763207, states[0] = -94.004015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1460513643, states[0] = -93.978391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1468743873, states[0] = -94.004332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1477091825, states[0] = 8.319097, states[40]= 0.003350
Saving checkpoint... 
Iteration: 1485620880, states[0] = -94.000522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493727253, states[0] = -94.004408, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.867797
 - CaMKt in component CaMK (millimolar): 0.005901
 - cass in component intracellular_ions (millimolar): 0.000098
 - nai in component intracellular_ions (millimolar): 6.892785
 - nass in component intracellular_ions (millimolar): 6.892905
 - ki in component intracellular_ions (millimolar): 144.943932
 - kss in component intracellular_ions (millimolar): 144.943917
 - cansr in component intracellular_ions (millimolar): 1.864297
 - cajsr in component intracellular_ions (millimolar): 1.863414
 - cai in component intracellular_ions (millimolar): 0.000102
 - m in component INa (dimensionless): 0.004017
 - hf in component INa (dimensionless): 0.860868
 - hs in component INa (dimensionless): 0.860871
 - j in component INa (dimensionless): 0.860886
 - hsp in component INa (dimensionless): 0.690799
 - jp in component INa (dimensionless): 0.860894
 - mL in component INaL (dimensionless): 0.000060
 - hL in component INaL (dimensionless): 0.700945
 - hLp in component INaL (dimensionless): 0.486953
 - a in component Ito (dimensionless): 0.000668
 - iF in component Ito (dimensionless): 0.999844
 - iS in component Ito (dimensionless): 0.883557
 - ap in component Ito (dimensionless): 0.000341
 - iFp in component Ito (dimensionless): 0.999844
 - iSp in component Ito (dimensionless): 0.923390
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.969571
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004700
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.114529
 - xs1 in component IKs (dimensionless): 0.140811
 - xs2 in component IKs (dimensionless): 0.000099
 - xk1 in component IK1 (dimensionless): 0.997596
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
16:50:02 (3009513): called boinc_finish(0)

</stderr_txt>
]]>


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