𝕏

Task 54844093

Name HuVeMOp_20240626145050251776_ORdGradInc_k_24-Pueyo_APDR-conf_320_0
Workunit 26041075
Created 26 Jun 2024, 12:51:19 UTC
Sent 26 Jun 2024, 15:27:27 UTC
Report deadline 30 Jun 2024, 1:03:27 UTC
Received 26 Jun 2024, 19:59:56 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 226910
Run time 1 hours 57 min 3 sec
CPU time 1 hours 54 min 40 sec
Validate state Valid
Credit 61.74
Device peak FLOPS 4.06 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.72 MB
Peak swap size 6.39 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626145050251776_ORdGradInc_k_24-Pueyo_APDR-conf_320.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626145050251776_ORdGradInc_k_24-Pueyo_APDR-conf_320_0_r352153232_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626145050251776_ORdGradInc_k_24-Pueyo_APDR-conf_320_0_r352153232_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 97.475895
     * GNaL_b in INaL: 0.005827
     * Gto_b in Ito: 0.094780
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.032201
     * GKs_b in IKs: 0.001756
     * GK1_b in IK1: 0.148784
     * Gncx_b in INaCa_i: 0.000972
     * Pnak_b in INaK: 65.861370
     * GKb_b in IKb: 0.003884
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.051033
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 17025395, states[0] = 18.825201, states[40]= 0.006435
Saving checkpoint... 
Iteration: 34105373, states[0] = -24.723683, states[40]= 0.000713
Saving checkpoint... 
Iteration: 50797831, states[0] = -94.924818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67833329, states[0] = -94.942355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 85006269, states[0] = 23.835811, states[40]= 0.125899
Saving checkpoint... 
Iteration: 102109610, states[0] = -27.312514, states[40]= 0.000599
Saving checkpoint... 
Iteration: 119085225, states[0] = -5.635621, states[40]= 0.003193
Saving checkpoint... 
Iteration: 136126698, states[0] = -43.455622, states[40]= 0.000078
Saving checkpoint... 
Iteration: 152836226, states[0] = -94.932882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 169885925, states[0] = -94.955452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 187132077, states[0] = -48.883174, states[40]= 0.000033
Saving checkpoint... 
Iteration: 203461464, states[0] = -94.974474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 220481621, states[0] = -94.977595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 237530814, states[0] = 17.968757, states[40]= 0.005524
Saving checkpoint... 
Iteration: 254811293, states[0] = -94.915294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 271844966, states[0] = -94.936664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 288438673, states[0] = -94.969704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 305625701, states[0] = -42.364908, states[40]= 0.000092
Saving checkpoint... 
Iteration: 322753229, states[0] = -94.855825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 339947173, states[0] = -94.971436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 356194464, states[0] = -94.748311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 373240370, states[0] = -94.837103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 390224498, states[0] = -94.810492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 407269366, states[0] = -94.875960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 424132836, states[0] = -49.650137, states[40]= 0.000029
Saving checkpoint... 
Iteration: 441226307, states[0] = -94.813692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 458459835, states[0] = -94.973753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 475466350, states[0] = -94.974871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 492526352, states[0] = 19.134247, states[40]= 0.006191
Saving checkpoint... 
Iteration: 509646347, states[0] = -64.293642, states[40]= 0.000002
Saving checkpoint... 
Iteration: 526221723, states[0] = -94.805320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 543220408, states[0] = -94.802861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 560264703, states[0] = -94.870352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 577343683, states[0] = -94.935715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 594532175, states[0] = 17.579477, states[40]= 0.005391
Saving checkpoint... 
Iteration: 611629823, states[0] = -46.530122, states[40]= 0.000048
Saving checkpoint... 
Iteration: 628394268, states[0] = -94.957366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 644255376, states[0] = -94.858469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 661397435, states[0] = -94.958381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 677877614, states[0] = -94.951318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 695062522, states[0] = 6.658170, states[40]= 0.004647
Saving checkpoint... 
Iteration: 712091515, states[0] = -10.539914, states[40]= 0.002179
Saving checkpoint... 
Iteration: 729117378, states[0] = -34.334804, states[40]= 0.000285
Saving checkpoint... 
Iteration: 746131797, states[0] = -48.568207, states[40]= 0.000035
Saving checkpoint... 
Iteration: 762638850, states[0] = -56.003566, states[40]= 0.000010
Saving checkpoint... 
Iteration: 779732640, states[0] = -94.824359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 796908143, states[0] = -94.961573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 814071042, states[0] = 2.821841, states[40]= 0.004434
Saving checkpoint... 
Iteration: 831221477, states[0] = -94.804642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 848433730, states[0] = -94.968170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 865559884, states[0] = 7.747074, states[40]= 0.004679
Saving checkpoint... 
Iteration: 882650499, states[0] = -69.347881, states[40]= 0.000001
Saving checkpoint... 
Iteration: 899789940, states[0] = -94.896921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 916566878, states[0] = 4.767151, states[40]= 0.004564
Saving checkpoint... 
Iteration: 933560280, states[0] = 7.585999, states[40]= 0.004675
Saving checkpoint... 
Iteration: 950799800, states[0] = -94.905608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 968058053, states[0] = 8.482048, states[40]= 0.004695
Saving checkpoint... 
Iteration: 984415027, states[0] = -94.963383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1001568356, states[0] = 4.094095, states[40]= 0.004525
Saving checkpoint... 
Iteration: 1018697158, states[0] = -94.754418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1035644764, states[0] = -62.479125, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1052865556, states[0] = -94.946055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1070005323, states[0] = 25.447058, states[40]= 0.149507
Saving checkpoint... 
Iteration: 1086714610, states[0] = -94.791339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1103857044, states[0] = -94.942128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1120941016, states[0] = -94.969586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1137913123, states[0] = -94.962746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1154606006, states[0] = -23.755934, states[40]= 0.000762
Saving checkpoint... 
Iteration: 1171856647, states[0] = -94.941889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1189072763, states[0] = 1.968844, states[40]= 0.004360
Saving checkpoint... 
Iteration: 1206011490, states[0] = 21.421065, states[40]= 0.036176
Saving checkpoint... 
Iteration: 1222609048, states[0] = -26.568702, states[40]= 0.000634
Saving checkpoint... 
Iteration: 1239674792, states[0] = -94.353787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1256802738, states[0] = -94.907820, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626145050251776_ORdGradInc_k_24-Pueyo_APDR-conf_320.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626145050251776_ORdGradInc_k_24-Pueyo_APDR-conf_320_0_r352153232_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626145050251776_ORdGradInc_k_24-Pueyo_APDR-conf_320_0_r352153232_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 97.475895
     * GNaL_b in INaL: 0.005827
     * Gto_b in Ito: 0.094780
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.032201
     * GKs_b in IKs: 0.001756
     * GK1_b in IK1: 0.148784
     * Gncx_b in INaCa_i: 0.000972
     * Pnak_b in INaK: 65.861370
     * GKb_b in IKb: 0.003884
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.051033
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1256802738
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.907820 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1270867382, states[0] = -94.946690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1287187177, states[0] = -94.722479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1303921894, states[0] = -94.964970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1320713943, states[0] = -94.789853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1337390339, states[0] = -94.955519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1353275247, states[0] = -94.881835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1369850549, states[0] = -94.938742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1386512860, states[0] = 21.266328, states[40]= 0.026556
Saving checkpoint... 
Iteration: 1402815849, states[0] = -94.917736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1418193068, states[0] = -94.743823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1432615394, states[0] = -32.471439, states[40]= 0.000358
Saving checkpoint... 
Iteration: 1448652695, states[0] = -72.262674, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1465316873, states[0] = -94.918419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1482038215, states[0] = 15.693816, states[40]= 0.005005
Saving checkpoint... 
Iteration: 1498218579, states[0] = -94.798712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1514548700, states[0] = -93.927007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1530625190, states[0] = 18.724362, states[40]= 0.007628
Saving checkpoint... 
Iteration: 1546788974, states[0] = -95.265790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1563100342, states[0] = -37.122601, states[40]= 0.000196
Saving checkpoint... 
Iteration: 1580062669, states[0] = -95.256047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1596991401, states[0] = -27.863737, states[40]= 0.000558
Saving checkpoint... 
Iteration: 1613870253, states[0] = -95.096905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1630963404, states[0] = -95.073532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1647637395, states[0] = 13.484726, states[40]= 0.005926
Saving checkpoint... 
Iteration: 1664567521, states[0] = -95.090360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1680538843, states[0] = -95.235327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1697697244, states[0] = -95.292175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1714657520, states[0] = -95.030237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1731494852, states[0] = -95.160361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1748726041, states[0] = 18.110558, states[40]= 0.007335
Saving checkpoint... 
Iteration: 1765538432, states[0] = 13.002361, states[40]= 0.005863
Saving checkpoint... 
Iteration: 1782345101, states[0] = 9.816739, states[40]= 0.005559
Saving checkpoint... 
Iteration: 1799137596, states[0] = 13.383686, states[40]= 0.005913
Saving checkpoint... 
Iteration: 1816135804, states[0] = -56.071384, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1833051809, states[0] = 10.400650, states[40]= 0.004742
Saving checkpoint... 
Iteration: 1849989000, states[0] = -94.997176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1866919387, states[0] = -94.976058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1884030879, states[0] = 17.874531, states[40]= 0.005511
Saving checkpoint... 
Iteration: 1901075007, states[0] = 0.693846, states[40]= 0.004232
Saving checkpoint... 
Iteration: 1916225563, states[0] = -94.814246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1932670369, states[0] = -93.535872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1949286581, states[0] = -94.894067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1966214132, states[0] = -94.790409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1983238978, states[0] = -94.834130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2000140675, states[0] = -57.982776, states[40]= 0.000007
Saving checkpoint... 
Iteration: 2017031104, states[0] = 17.886489, states[40]= 0.005494
Saving checkpoint... 
Iteration: 2033839922, states[0] = -94.932614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2050911726, states[0] = -94.961688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2067592453, states[0] = -11.352318, states[40]= 0.002024
Saving checkpoint... 
Iteration: 2084429351, states[0] = -94.966206, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.854350
 - CaMKt in component CaMK (millimolar): 0.007161
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.684035
 - nass in component intracellular_ions (millimolar): 6.684096
 - ki in component intracellular_ions (millimolar): 145.291176
 - kss in component intracellular_ions (millimolar): 145.291157
 - cansr in component intracellular_ions (millimolar): 1.318523
 - cajsr in component intracellular_ions (millimolar): 1.280104
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003636
 - hf in component INa (dimensionless): 0.879174
 - hs in component INa (dimensionless): 0.879169
 - j in component INa (dimensionless): 0.879139
 - hsp in component INa (dimensionless): 0.724273
 - jp in component INa (dimensionless): 0.879118
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.707780
 - hLp in component INaL (dimensionless): 0.447910
 - a in component Ito (dimensionless): 0.000625
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.618271
 - ap in component Ito (dimensionless): 0.000319
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.692790
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.936079
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999886
 - jca in component ICaL (dimensionless): 0.999977
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001618
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.321828
 - xs1 in component IKs (dimensionless): 0.243212
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997350
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
12:30:04 (5340): called boinc_finish(0)

</stderr_txt>
]]>