𝕏

Task 54843406

Name HuVeMOp_20240626145050251776_ORdGradInc_k_24-Pueyo_APDR-conf_104_1
Workunit 26040731
Created 26 Jun 2024, 12:50:59 UTC
Sent 26 Jun 2024, 15:25:09 UTC
Report deadline 30 Jun 2024, 1:01:09 UTC
Received 28 Jun 2024, 8:13:03 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 237903
Run time 2 hours 35 min 23 sec
CPU time 1 hours 0 min 40 sec
Validate state Valid
Credit 63.59
Device peak FLOPS 5.42 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.14 MB
Peak swap size 5.32 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626145050251776_ORdGradInc_k_24-Pueyo_APDR-conf_104.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626145050251776_ORdGradInc_k_24-Pueyo_APDR-conf_104_1_r678775630_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626145050251776_ORdGradInc_k_24-Pueyo_APDR-conf_104_1_r678775630_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 99.791134
     * GNaL_b in INaL: 0.009307
     * Gto_b in Ito: 0.066860
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033035
     * GKs_b in IKs: 0.001919
     * GK1_b in IK1: 0.162167
     * Gncx_b in INaCa_i: 0.000957
     * Pnak_b in INaK: 61.463499
     * GKb_b in IKb: 0.003954
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.041015
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 14098352, states[0] = -14.422112, states[40]= 0.001553
Saving checkpoint... 
Iteration: 25924491, states[0] = -95.011988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 38911655, states[0] = -95.003787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 53229863, states[0] = -94.872841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 71068676, states[0] = 5.635822, states[40]= 0.004894
Saving checkpoint... 
Iteration: 88288756, states[0] = -94.936902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 100928951, states[0] = -95.000307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 117725281, states[0] = -94.860692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 135030830, states[0] = 20.590862, states[40]= 0.006357
Saving checkpoint... 
Iteration: 147763391, states[0] = -94.910739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 166124820, states[0] = -37.887033, states[40]= 0.000196
Saving checkpoint... 
Iteration: 180701382, states[0] = -94.818367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 193353120, states[0] = -94.974834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 205611468, states[0] = -25.477113, states[40]= 0.000748
Saving checkpoint... 
Iteration: 230726840, states[0] = -94.862183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 245148233, states[0] = -64.299021, states[40]= 0.000003
Saving checkpoint... 
Iteration: 258117549, states[0] = -31.023596, states[40]= 0.000467
Saving checkpoint... 
Iteration: 272097197, states[0] = -12.599910, states[40]= 0.001861
Saving checkpoint... 
Iteration: 283568672, states[0] = 5.719946, states[40]= 0.004896
Saving checkpoint... 
Iteration: 298863846, states[0] = -94.979210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 314090802, states[0] = -7.279008, states[40]= 0.002951
Saving checkpoint... 
Iteration: 327598665, states[0] = -13.897385, states[40]= 0.001648
Saving checkpoint... 
Iteration: 339868634, states[0] = -94.981063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 352020049, states[0] = 23.680634, states[40]= 0.010205
Saving checkpoint... 
Iteration: 363688128, states[0] = -94.789133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 380668903, states[0] = -93.173365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 395576236, states[0] = 1.998926, states[40]= 0.004583
Saving checkpoint... 
Iteration: 411762634, states[0] = -94.909358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 425058414, states[0] = 10.195643, states[40]= 0.005106
Saving checkpoint... 
Iteration: 443343575, states[0] = -94.970124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 457817461, states[0] = -94.955571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 471802877, states[0] = -94.945645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 481541270, states[0] = 16.929202, states[40]= 0.005490
Saving checkpoint... 
Iteration: 495422411, states[0] = -94.997137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 509803848, states[0] = -94.946329, states[40]= 0.000000
Saving checkpoint... 
Iteration: 521619218, states[0] = -32.565619, states[40]= 0.000392
Saving checkpoint... 
Iteration: 536022591, states[0] = 23.036819, states[40]= 0.008537
Saving checkpoint... 
Iteration: 543322856, states[0] = -94.958839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 557304746, states[0] = -94.946948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 572333469, states[0] = -94.964857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 587365326, states[0] = -94.979626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599108766, states[0] = -23.025864, states[40]= 0.000858
Saving checkpoint... 
Iteration: 608994884, states[0] = -95.009178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 625884951, states[0] = -94.986694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 639839121, states[0] = -94.967784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 653503320, states[0] = 37.658666, states[40]= 0.139773
Saving checkpoint... 
Iteration: 667828832, states[0] = -94.962242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685270831, states[0] = -94.917849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 698825986, states[0] = -94.960594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 710095136, states[0] = -10.815282, states[40]= 0.002196
Saving checkpoint... 
Iteration: 726457225, states[0] = -95.003852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 740261768, states[0] = -94.908208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 755759228, states[0] = -94.905343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 767321449, states[0] = -94.957860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 780588205, states[0] = -5.334821, states[40]= 0.003376
Saving checkpoint... 
Iteration: 789204336, states[0] = -94.823357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 800808472, states[0] = -94.949429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 812520887, states[0] = 23.474213, states[40]= 0.009550
Saving checkpoint... 
Iteration: 828755362, states[0] = -94.900809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 846944195, states[0] = -95.001477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861681120, states[0] = -94.743526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 873069744, states[0] = 5.220052, states[40]= 0.004863
Saving checkpoint... 
Iteration: 885045780, states[0] = 15.224226, states[40]= 0.005329
Saving checkpoint... 
Iteration: 898693368, states[0] = -94.801982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 915081701, states[0] = -1.061592, states[40]= 0.004180
Saving checkpoint... 
Iteration: 927970972, states[0] = -95.005876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 935971794, states[0] = -95.005991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 955281085, states[0] = -94.927543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 968536349, states[0] = 18.718352, states[40]= 0.005784
Saving checkpoint... 
Iteration: 980038771, states[0] = 17.848672, states[40]= 0.005620
Saving checkpoint... 
Iteration: 993377831, states[0] = -94.984058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1007037356, states[0] = 18.359579, states[40]= 0.005711
Saving checkpoint... 
Iteration: 1021273242, states[0] = -94.920062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1036918648, states[0] = -94.995936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1051792746, states[0] = -94.937509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1067523070, states[0] = 22.909653, states[40]= 0.008311
Saving checkpoint... 
Iteration: 1078856741, states[0] = -94.975793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1095058157, states[0] = 10.302203, states[40]= 0.005110
Saving checkpoint... 
Iteration: 1107274417, states[0] = -94.921165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1122321116, states[0] = -94.957449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1140285522, states[0] = -94.931389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1154479100, states[0] = -95.006884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1168190495, states[0] = -94.795240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1182330014, states[0] = -94.962604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1194272821, states[0] = -94.919544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1208486276, states[0] = -95.007788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1223775377, states[0] = -94.922029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232651014, states[0] = -68.045759, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1248681410, states[0] = -94.746982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1261014329, states[0] = 24.990830, states[40]= 0.021138
Saving checkpoint... 
Iteration: 1274953747, states[0] = -95.002944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1289056413, states[0] = 11.019005, states[40]= 0.005135
Saving checkpoint... 
Iteration: 1301961043, states[0] = -95.004139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1318276996, states[0] = -94.923525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1331113383, states[0] = -27.210906, states[40]= 0.000663
Saving checkpoint... 
Iteration: 1347864351, states[0] = -94.978793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1362970442, states[0] = -95.005545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1382397323, states[0] = -94.990088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1397343416, states[0] = -94.969488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1411193822, states[0] = -94.802644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415793085, states[0] = -94.937569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1424345673, states[0] = -94.970565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437738718, states[0] = -94.878999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1455961248, states[0] = -95.004082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1470072329, states[0] = 3.980364, states[40]= 0.004770
Saving checkpoint... 
Iteration: 1484243218, states[0] = -94.885125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497224756, states[0] = -94.858118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1509518835, states[0] = -95.162145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1525980425, states[0] = -95.106868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1539295586, states[0] = -95.265592, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626145050251776_ORdGradInc_k_24-Pueyo_APDR-conf_104.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626145050251776_ORdGradInc_k_24-Pueyo_APDR-conf_104_1_r678775630_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626145050251776_ORdGradInc_k_24-Pueyo_APDR-conf_104_1_r678775630_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 99.791134
     * GNaL_b in INaL: 0.009307
     * Gto_b in Ito: 0.066860
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033035
     * GKs_b in IKs: 0.001919
     * GK1_b in IK1: 0.162167
     * Gncx_b in INaCa_i: 0.000957
     * Pnak_b in INaK: 61.463499
     * GKb_b in IKb: 0.003954
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.041015
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1539295586
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -95.265592 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading resultsTime...
Loading resultsAPD90...
Loading resultsAPD75...
Loading resultsAPD50...
Loading resultsAPD25...
Loading resultsAPD10...
Loading resultsTriangulation...
Loading resultsMaxV...
Loading resultsMinV...
Loading resultsMaxDiffV...
Loading resultsMinDiffV...
Copy resultsTime...
Copy resultsAPD90...
Copy resultsAPD75...
Copy resultsAPD50...
Copy resultsAPD25...
Copy resultsAPD10...
Copy resultsTriangulation...
Copy resultsMaxV...
Copy resultsMinV...
Copy resultsMaxDiffV...
Copy resultsMinDiffV...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1572826333, states[0] = -95.212831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1587764631, states[0] = -95.092676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1596811832, states[0] = -95.195267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1607935818, states[0] = -95.230446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1622165508, states[0] = 0.113903, states[40]= 0.004935
Saving checkpoint... 
Iteration: 1633356874, states[0] = -95.039220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1644455551, states[0] = -95.014687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1663919155, states[0] = -55.259144, states[40]= 0.000015
Saving checkpoint... 
Iteration: 1680621564, states[0] = 22.298042, states[40]= 0.010337
Saving checkpoint... 
Iteration: 1691077698, states[0] = -95.274390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1705376111, states[0] = -95.128626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1719542933, states[0] = -95.241377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1731651320, states[0] = 8.490421, states[40]= 0.005833
Saving checkpoint... 
Iteration: 1747084829, states[0] = -95.148217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1762110980, states[0] = -95.197448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1780421912, states[0] = -95.214263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1797026928, states[0] = 20.188607, states[40]= 0.008139
Saving checkpoint... 
Iteration: 1810872434, states[0] = -95.028950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1823377750, states[0] = -95.018548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1837108053, states[0] = -23.787004, states[40]= 0.000824
Saving checkpoint... 
Iteration: 1851899057, states[0] = -95.006105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1863787969, states[0] = -94.944367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1877918665, states[0] = -95.002938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1888458776, states[0] = -95.008965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1901833892, states[0] = -94.968083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1910655034, states[0] = -74.432379, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1919365244, states[0] = -94.981087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1934692111, states[0] = -94.800078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1949020517, states[0] = 23.555881, states[40]= 0.009820
Saving checkpoint... 
Iteration: 1966074631, states[0] = 2.813549, states[40]= 0.004667
Saving checkpoint... 
Iteration: 1980348573, states[0] = -94.971966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1992586445, states[0] = -4.108780, states[40]= 0.003631
Saving checkpoint... 
Iteration: 2002320800, states[0] = -94.956907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2018791677, states[0] = -94.936154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2034741781, states[0] = -94.882897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2049546717, states[0] = 14.862801, states[40]= 0.005304
Saving checkpoint... 
Iteration: 2067242160, states[0] = -94.883337, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2083435595, states[0] = -94.999034, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.884717
 - CaMKt in component CaMK (millimolar): 0.007034
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.871374
 - nass in component intracellular_ions (millimolar): 6.871434
 - ki in component intracellular_ions (millimolar): 145.105701
 - kss in component intracellular_ions (millimolar): 145.105681
 - cansr in component intracellular_ions (millimolar): 1.317128
 - cajsr in component intracellular_ions (millimolar): 1.278768
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003625
 - hf in component INa (dimensionless): 0.879703
 - hs in component INa (dimensionless): 0.879699
 - j in component INa (dimensionless): 0.879671
 - hsp in component INa (dimensionless): 0.725271
 - jp in component INa (dimensionless): 0.879653
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.708518
 - hLp in component INaL (dimensionless): 0.448692
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.615889
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.689016
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.926971
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999858
 - jca in component ICaL (dimensionless): 0.999975
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001635
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.349908
 - xs1 in component IKs (dimensionless): 0.254029
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997342
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
09:33:33 (15196): called boinc_finish(0)

</stderr_txt>
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