𝕏

Task 54837268

Name HuVeMOp_20240626144554837168_ORdGradInc_k_24-Drouin_ENDO_1000-conf_326_0
Workunit 26037668
Created 26 Jun 2024, 12:46:52 UTC
Sent 26 Jun 2024, 14:34:58 UTC
Report deadline 29 Jun 2024, 14:34:58 UTC
Received 27 Jun 2024, 20:22:32 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 239842
Run time 1 hours 5 min 35 sec
CPU time 55 min 59 sec
Validate state Valid
Credit 42.39
Device peak FLOPS 6.87 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.47 MB
Peak swap size 3.69 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.20.5</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626144554837168_ORdGradInc_k_24-Drouin_ENDO_1000-conf_326.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626144554837168_ORdGradInc_k_24-Drouin_ENDO_1000-conf_326_0_r625714318_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626144554837168_ORdGradInc_k_24-Drouin_ENDO_1000-conf_326_0_r625714318_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 100.079679
     * GNaL_b in INaL: 0.006091
     * Gto_b in Ito: 0.086059
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.033262
     * GKs_b in IKs: 0.001782
     * GK1_b in IK1: 0.148583
     * Gncx_b in INaCa_i: 0.000955
     * Pnak_b in INaK: 62.824755
     * GKb_b in IKb: 0.003819
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032332
     * celltype in environment: 0.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 8268976, states[0] = -94.014888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 16603565, states[0] = -4.832561, states[40]= 0.003262
Saving checkpoint... 
Iteration: 24151632, states[0] = -50.517265, states[40]= 0.000158
Saving checkpoint... 
Iteration: 32021582, states[0] = 32.083223, states[40]= 0.001124
Saving checkpoint... 
Iteration: 40400107, states[0] = -94.194686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 47952204, states[0] = -94.237238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 56276421, states[0] = -93.991959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 64940212, states[0] = -94.248020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 72499477, states[0] = -94.275997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 80815641, states[0] = -94.114870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 89225108, states[0] = -93.784705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 96838659, states[0] = -94.164239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 105136377, states[0] = -39.378792, states[40]= 0.000596
Saving checkpoint... 
Iteration: 113507658, states[0] = 31.331413, states[40]= 0.145243
Saving checkpoint... 
Iteration: 121471673, states[0] = -94.283374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 129510269, states[0] = 31.741072, states[40]= 0.058422
Saving checkpoint... 
Iteration: 137963087, states[0] = -94.281786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 145808023, states[0] = -94.111845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 154059113, states[0] = 17.880881, states[40]= 0.000362
Saving checkpoint... 
Iteration: 162488427, states[0] = -94.291942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170404931, states[0] = -94.249607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 178269015, states[0] = -93.999387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 186631476, states[0] = -35.087126, states[40]= 0.000885
Saving checkpoint... 
Iteration: 194271261, states[0] = -94.007536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 202357541, states[0] = -94.200881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 210921953, states[0] = -94.262123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 218760916, states[0] = -93.968931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 227197740, states[0] = -93.520741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 235895542, states[0] = -94.241985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 243442526, states[0] = -94.273911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 251514051, states[0] = 32.279369, states[40]= 0.015586
Saving checkpoint... 
Iteration: 260288359, states[0] = -94.061825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 267889933, states[0] = -94.236642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 276281886, states[0] = -94.042231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 284628481, states[0] = -32.305703, states[40]= 0.001078
Saving checkpoint... 
Iteration: 292045756, states[0] = 23.615771, states[40]= 0.000136
Saving checkpoint... 
Iteration: 300235252, states[0] = -93.851039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 308657031, states[0] = -59.876831, states[40]= 0.000037
Saving checkpoint... 
Iteration: 316084122, states[0] = 5.587366, states[40]= 0.001624
Saving checkpoint... 
Iteration: 324223641, states[0] = -93.786791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 333027600, states[0] = 30.214310, states[40]= 0.000171
Saving checkpoint... 
Iteration: 340417462, states[0] = -94.257899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 348505514, states[0] = 32.206015, states[40]= 0.306444
Saving checkpoint... 
Iteration: 356854646, states[0] = -94.195548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 364242287, states[0] = -93.885646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 371978341, states[0] = -94.287642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 380337460, states[0] = -94.169301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 388125667, states[0] = -29.671144, states[40]= 0.001217
Saving checkpoint... 
Iteration: 396412134, states[0] = -94.253478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 404335572, states[0] = -94.165849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 412384882, states[0] = -94.230157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 421143579, states[0] = -46.696497, states[40]= 0.000247
Saving checkpoint... 
Iteration: 429316081, states[0] = -94.128619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 437600007, states[0] = -5.053030, states[40]= 0.002326
Saving checkpoint... 
Iteration: 445688640, states[0] = -92.510811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 453547555, states[0] = 22.871616, states[40]= 0.000156
Saving checkpoint... 
Iteration: 461572585, states[0] = 11.559034, states[40]= 0.000869
Saving checkpoint... 
Iteration: 469853541, states[0] = -94.192685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 477844821, states[0] = -94.179877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 486377143, states[0] = -94.221341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 494835516, states[0] = -94.164679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 502929636, states[0] = -94.263785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 511145460, states[0] = -48.535887, states[40]= 0.000194
Saving checkpoint... 
Iteration: 519638833, states[0] = -42.090634, states[40]= 0.000434
Saving checkpoint... 
Iteration: 527663247, states[0] = -66.181236, states[40]= 0.000014
Saving checkpoint... 
Iteration: 535550001, states[0] = 21.843149, states[40]= 0.000187
Saving checkpoint... 
Iteration: 543491724, states[0] = -94.289800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 551359302, states[0] = -94.199469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 559631327, states[0] = -34.970738, states[40]= 0.000892
Saving checkpoint... 
Iteration: 567582406, states[0] = 6.529296, states[40]= 0.001496
Saving checkpoint... 
Iteration: 575937456, states[0] = -94.267399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 584513885, states[0] = 32.268740, states[40]= 0.016515
Saving checkpoint... 
Iteration: 592097672, states[0] = -3.163312, states[40]= 0.002376
Saving checkpoint... 
Iteration: 599853116, states[0] = -94.190551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 608407592, states[0] = -94.247582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 616606402, states[0] = -10.918097, states[40]= 0.001779
Saving checkpoint... 
Iteration: 624423230, states[0] = -94.258375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 632835347, states[0] = -94.162751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 640474342, states[0] = -94.283084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 648141371, states[0] = -44.541278, states[40]= 0.000324
Saving checkpoint... 
Iteration: 656202153, states[0] = -93.615973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 664389439, states[0] = -94.231541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 672002470, states[0] = 42.532057, states[40]= 0.832926
Saving checkpoint... 
Iteration: 680194651, states[0] = -93.367303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 688374738, states[0] = -94.216338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 696445602, states[0] = -94.270235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 704357772, states[0] = -94.195642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 712787137, states[0] = -94.052923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 720748155, states[0] = -93.908925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 729002405, states[0] = 42.923051, states[40]= 0.844254
Saving checkpoint... 
Iteration: 737185598, states[0] = -91.371200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 745221979, states[0] = -93.771944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 753123139, states[0] = -27.295430, states[40]= 0.001269
Saving checkpoint... 
Iteration: 761107481, states[0] = -11.980527, states[40]= 0.001660
Saving checkpoint... 
Iteration: 769300142, states[0] = -94.087699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 777558600, states[0] = 18.094067, states[40]= 0.000348
Saving checkpoint... 
Iteration: 785555487, states[0] = 19.474490, states[40]= 0.000279
Saving checkpoint... 
Iteration: 793706909, states[0] = -93.668848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 802333478, states[0] = -94.157525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 809972982, states[0] = -94.280594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 818253247, states[0] = -93.930309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 826977605, states[0] = -94.282020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 834666748, states[0] = -69.998629, states[40]= 0.000007
Saving checkpoint... 
Iteration: 843080660, states[0] = 7.465255, states[40]= 0.001370
Saving checkpoint... 
Iteration: 851291709, states[0] = -94.064335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 859114752, states[0] = -19.252133, states[40]= 0.001156
Saving checkpoint... 
Iteration: 867330001, states[0] = -94.150596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 875586441, states[0] = 4.279096, states[40]= 0.001801
Saving checkpoint... 
Iteration: 883192142, states[0] = -93.139245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 891150111, states[0] = -53.086074, states[40]= 0.000103
Saving checkpoint... 
Iteration: 899947836, states[0] = -94.268930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 907779965, states[0] = -94.028661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 915952516, states[0] = -94.270957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 924379109, states[0] = -94.218231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 932382066, states[0] = -94.221185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 940923899, states[0] = -94.255060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 949174369, states[0] = -79.524943, states[40]= 0.000002
Saving checkpoint... 
Iteration: 957128642, states[0] = -32.447966, states[40]= 0.001069
Saving checkpoint... 
Iteration: 965135109, states[0] = -38.529802, states[40]= 0.000641
Saving checkpoint... 
Iteration: 973542374, states[0] = 24.986441, states[40]= 0.000106
Saving checkpoint... 
Iteration: 981750256, states[0] = -93.915239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 989976643, states[0] = -94.279764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 998117389, states[0] = -21.826750, states[40]= 0.001168
Saving checkpoint... 
Iteration: 1006220740, states[0] = -93.761402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1014504762, states[0] = 33.363727, states[40]= 0.397061
Saving checkpoint... 
Iteration: 1022749841, states[0] = -93.912893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031076927, states[0] = 9.399894, states[40]= 0.001120
Saving checkpoint... 
Iteration: 1039339539, states[0] = -94.164882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1047753761, states[0] = -93.929753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1055627718, states[0] = -31.581500, states[40]= 0.001123
Saving checkpoint... 
Iteration: 1063706119, states[0] = -93.658214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1071882786, states[0] = -94.220259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1079284520, states[0] = -94.040744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1087758399, states[0] = -93.948639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1095952772, states[0] = -94.268948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1103699317, states[0] = -93.555221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1111825249, states[0] = -94.138876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1120221122, states[0] = -93.762301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1128003034, states[0] = 39.378057, states[40]= 0.710690
Saving checkpoint... 
Iteration: 1136110050, states[0] = -14.546169, states[40]= 0.001402
Saving checkpoint... 
Iteration: 1144283411, states[0] = -94.036591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1152481492, states[0] = -94.279475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1160290807, states[0] = -94.058116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1168552029, states[0] = 20.979241, states[40]= 0.000218
Saving checkpoint... 
Iteration: 1176481822, states[0] = -94.279299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1184685198, states[0] = -91.149334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1192906023, states[0] = -94.239454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1201040091, states[0] = 25.884632, states[40]= 0.000090
Saving checkpoint... 
Iteration: 1209320537, states[0] = -94.128501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1217374216, states[0] = -94.209491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1225419195, states[0] = -94.248612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1233164337, states[0] = -67.323999, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1241259302, states[0] = -93.950449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1249131310, states[0] = -34.944448, states[40]= 0.000894
Saving checkpoint... 
Iteration: 1256910832, states[0] = -94.242343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1265169981, states[0] = -73.808953, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1273123847, states[0] = -27.952650, states[40]= 0.001263
Saving checkpoint... 
Iteration: 1281210194, states[0] = -93.689437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1289158267, states[0] = -61.080559, states[40]= 0.000031
Saving checkpoint... 
Iteration: 1297068369, states[0] = 13.594133, states[40]= 0.000669
Saving checkpoint... 
Iteration: 1305154456, states[0] = -57.326577, states[40]= 0.000055
Saving checkpoint... 
Iteration: 1313318155, states[0] = -94.122415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1320987039, states[0] = -94.279234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1329307197, states[0] = -94.098163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1337450286, states[0] = -94.264935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1345326119, states[0] = -94.137745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1353562718, states[0] = 16.231229, states[40]= 0.000462
Saving checkpoint... 
Iteration: 1361556641, states[0] = 18.968057, states[40]= 0.000303
Saving checkpoint... 
Iteration: 1369553416, states[0] = 20.380942, states[40]= 0.000241
Saving checkpoint... 
Iteration: 1377430373, states[0] = -94.253883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1385438330, states[0] = -94.258305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1393169496, states[0] = -73.209975, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1401344340, states[0] = -94.168168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1409396137, states[0] = -94.228755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1417464552, states[0] = -94.270207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1425658065, states[0] = -60.876760, states[40]= 0.000032
Saving checkpoint... 
Iteration: 1433292093, states[0] = -94.058444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1441310194, states[0] = -94.103708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1449525553, states[0] = 30.785511, states[40]= 0.000310
Saving checkpoint... 
Iteration: 1457308406, states[0] = -94.099440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1465554634, states[0] = 19.850959, states[40]= 0.000263
Saving checkpoint... 
Iteration: 1473824815, states[0] = -94.133739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1481294984, states[0] = -94.065757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1489464802, states[0] = -94.269457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497883569, states[0] = -94.215996, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.156637
 - CaMKt in component CaMK (millimolar): 0.018544
 - cass in component intracellular_ions (millimolar): 0.000099
 - nai in component intracellular_ions (millimolar): 7.277072
 - nass in component intracellular_ions (millimolar): 7.277198
 - ki in component intracellular_ions (millimolar): 144.480012
 - kss in component intracellular_ions (millimolar): 144.479991
 - cansr in component intracellular_ions (millimolar): 1.988287
 - cajsr in component intracellular_ions (millimolar): 1.943819
 - cai in component intracellular_ions (millimolar): 0.000102
 - m in component INa (dimensionless): 0.003901
 - hf in component INa (dimensionless): 0.866457
 - hs in component INa (dimensionless): 0.866446
 - j in component INa (dimensionless): 0.866370
 - hsp in component INa (dimensionless): 0.700764
 - jp in component INa (dimensionless): 0.866316
 - mL in component INaL (dimensionless): 0.000057
 - hL in component INaL (dimensionless): 0.683868
 - hLp in component INaL (dimensionless): 0.414177
 - a in component Ito (dimensionless): 0.000656
 - iF in component Ito (dimensionless): 0.999851
 - iS in component Ito (dimensionless): 0.597035
 - ap in component Ito (dimensionless): 0.000334
 - iFp in component Ito (dimensionless): 0.999851
 - iSp in component Ito (dimensionless): 0.662946
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.901524
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999767
 - jca in component ICaL (dimensionless): 0.999966
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004876
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.398300
 - xs1 in component IKs (dimensionless): 0.288942
 - xs2 in component IKs (dimensionless): 0.000095
 - xk1 in component IK1 (dimensionless): 0.997527
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
15:22:19 (2987891): called boinc_finish(0)

</stderr_txt>
]]>


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