𝕏

Task 54836378

Name HuVeMOp_20240626144554837168_ORdGradInc_k_24-Pueyo_APDR-conf_707_0
Workunit 26037223
Created 26 Jun 2024, 12:46:10 UTC
Sent 26 Jun 2024, 14:22:06 UTC
Report deadline 29 Jun 2024, 23:58:06 UTC
Received 30 Jun 2024, 5:24:03 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 234060
Run time 1 hours 32 min 49 sec
CPU time 1 hours 18 min 11 sec
Validate state Valid
Credit 60.14
Device peak FLOPS 4.51 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.34 MB
Peak swap size 5.47 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626144554837168_ORdGradInc_k_24-Pueyo_APDR-conf_707.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626144554837168_ORdGradInc_k_24-Pueyo_APDR-conf_707_0_r1879259333_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626144554837168_ORdGradInc_k_24-Pueyo_APDR-conf_707_0_r1879259333_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 97.012700
     * GNaL_b in INaL: 0.006113
     * Gto_b in Ito: 0.080669
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033031
     * GKs_b in IKs: 0.001810
     * GK1_b in IK1: 0.169343
     * Gncx_b in INaCa_i: 0.000952
     * Pnak_b in INaK: 69.543004
     * GKb_b in IKb: 0.003783
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.039567
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 27623892, states[0] = -47.318910, states[40]= 0.000043
Saving checkpoint... 
Iteration: 55796116, states[0] = -95.097255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84697527, states[0] = -94.959292, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626144554837168_ORdGradInc_k_24-Pueyo_APDR-conf_707.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626144554837168_ORdGradInc_k_24-Pueyo_APDR-conf_707_0_r1879259333_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626144554837168_ORdGradInc_k_24-Pueyo_APDR-conf_707_0_r1879259333_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 97.012700
     * GNaL_b in INaL: 0.006113
     * Gto_b in Ito: 0.080669
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033031
     * GKs_b in IKs: 0.001810
     * GK1_b in IK1: 0.169343
     * Gncx_b in INaCa_i: 0.000952
     * Pnak_b in INaK: 69.543004
     * GKb_b in IKb: 0.003783
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.039567
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 84697527
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.959292 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 106573302, states[0] = 1.153562, states[40]= 0.004420
Saving checkpoint... 
Iteration: 130249632, states[0] = -95.035237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 156603592, states[0] = -23.616566, states[40]= 0.000765
Saving checkpoint... 
Iteration: 182350095, states[0] = -95.109541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 208000601, states[0] = 34.320413, states[40]= 0.002019
Saving checkpoint... 
Iteration: 234502280, states[0] = 42.082367, states[40]= 0.110175
Saving checkpoint... 
Iteration: 259754910, states[0] = -95.039202, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626144554837168_ORdGradInc_k_24-Pueyo_APDR-conf_707.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626144554837168_ORdGradInc_k_24-Pueyo_APDR-conf_707_0_r1879259333_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626144554837168_ORdGradInc_k_24-Pueyo_APDR-conf_707_0_r1879259333_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 97.012700
     * GNaL_b in INaL: 0.006113
     * Gto_b in Ito: 0.080669
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033031
     * GKs_b in IKs: 0.001810
     * GK1_b in IK1: 0.169343
     * Gncx_b in INaCa_i: 0.000952
     * Pnak_b in INaK: 69.543004
     * GKb_b in IKb: 0.003783
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.039567
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 259754910
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -95.039202 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 288887285, states[0] = -95.122857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 316620330, states[0] = -40.135264, states[40]= 0.000128
Saving checkpoint... 
Iteration: 341693524, states[0] = -94.942806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 364694182, states[0] = -94.944112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 386924290, states[0] = -95.132497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 408974070, states[0] = -95.141259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432317336, states[0] = -95.091861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 454904266, states[0] = -95.127607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 478988624, states[0] = -95.143098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 504139390, states[0] = -61.738592, states[40]= 0.000004
Saving checkpoint... 
Iteration: 527380484, states[0] = -95.120499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 549652408, states[0] = -81.716547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 573617609, states[0] = -37.349554, states[40]= 0.000190
Saving checkpoint... 
Iteration: 595260524, states[0] = -95.045178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 621055524, states[0] = 9.612142, states[40]= 0.004936
Saving checkpoint... 
Iteration: 646881851, states[0] = -95.120872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 670086170, states[0] = -7.298746, states[40]= 0.002925
Saving checkpoint... 
Iteration: 692825401, states[0] = -95.096406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 717250786, states[0] = -95.034031, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626144554837168_ORdGradInc_k_24-Pueyo_APDR-conf_707.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626144554837168_ORdGradInc_k_24-Pueyo_APDR-conf_707_0_r1879259333_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626144554837168_ORdGradInc_k_24-Pueyo_APDR-conf_707_0_r1879259333_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 97.012700
     * GNaL_b in INaL: 0.006113
     * Gto_b in Ito: 0.080669
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033031
     * GKs_b in IKs: 0.001810
     * GK1_b in IK1: 0.169343
     * Gncx_b in INaCa_i: 0.000952
     * Pnak_b in INaK: 69.543004
     * GKb_b in IKb: 0.003783
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.039567
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 717250786
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -95.034031 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 747838575, states[0] = -95.103311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 769995023, states[0] = -95.143661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 793093398, states[0] = -13.708435, states[40]= 0.001666
Saving checkpoint... 
Iteration: 816438099, states[0] = -95.135073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 839490827, states[0] = -95.143129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 863808903, states[0] = -95.086237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 888765736, states[0] = -95.050472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 915426408, states[0] = -95.132617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 939811369, states[0] = -95.087798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 963266978, states[0] = -95.051687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 985237046, states[0] = -95.016231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1008895521, states[0] = -95.124834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1034205826, states[0] = -94.966080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1058227671, states[0] = -95.002668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1085295800, states[0] = -95.076842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1113193397, states[0] = -94.942044, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1136320741, states[0] = -95.093442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1159280870, states[0] = -95.064649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1181779632, states[0] = -95.063543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1207290101, states[0] = -95.072343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232390952, states[0] = -95.123348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1255279416, states[0] = -95.063303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1281863633, states[0] = -95.113964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1304362070, states[0] = -95.113338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1326373514, states[0] = -95.117599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1351990110, states[0] = -95.142715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1374879989, states[0] = -95.119789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1399486963, states[0] = -95.142304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1424200054, states[0] = -94.954959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1447820334, states[0] = -95.093002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1472569823, states[0] = 3.122071, states[40]= 0.004608
Saving checkpoint... 
Iteration: 1495336544, states[0] = -95.101817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1520107355, states[0] = 26.314239, states[40]= 0.089396
Saving checkpoint... 
Iteration: 1544252854, states[0] = -95.158766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1568317911, states[0] = -95.324769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1592188536, states[0] = -25.851744, states[40]= 0.000665
Saving checkpoint... 
Iteration: 1617814958, states[0] = -95.326980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1643106841, states[0] = 26.644065, states[40]= 0.100559
Saving checkpoint... 
Iteration: 1666592511, states[0] = -30.493136, states[40]= 0.000437
Saving checkpoint... 
Iteration: 1691261898, states[0] = -95.220309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1715396943, states[0] = -95.409139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1742388613, states[0] = -95.403840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1767224696, states[0] = -95.342340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1789896615, states[0] = -35.128783, states[40]= 0.000256
Saving checkpoint... 
Iteration: 1814898165, states[0] = -95.166524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1838228884, states[0] = -95.026048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1860848574, states[0] = -95.118524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1883225241, states[0] = -95.004345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1909858379, states[0] = -95.114107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1934030256, states[0] = 18.971874, states[40]= 0.006047
Saving checkpoint... 
Iteration: 1959049177, states[0] = 12.164302, states[40]= 0.005020
Saving checkpoint... 
Iteration: 1984274003, states[0] = -95.058135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2007430765, states[0] = -95.132936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2031932265, states[0] = -95.133148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2057324163, states[0] = -95.094804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2079354239, states[0] = -95.109593, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -95.019185
 - CaMKt in component CaMK (millimolar): 0.006990
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.561798
 - nass in component intracellular_ions (millimolar): 6.561858
 - ki in component intracellular_ions (millimolar): 145.415203
 - kss in component intracellular_ions (millimolar): 145.415183
 - cansr in component intracellular_ions (millimolar): 1.314025
 - cajsr in component intracellular_ions (millimolar): 1.276131
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003576
 - hf in component INa (dimensionless): 0.882022
 - hs in component INa (dimensionless): 0.882018
 - j in component INa (dimensionless): 0.881991
 - hsp in component INa (dimensionless): 0.729652
 - jp in component INa (dimensionless): 0.881973
 - mL in component INaL (dimensionless): 0.000048
 - hL in component INaL (dimensionless): 0.713661
 - hLp in component INaL (dimensionless): 0.457509
 - a in component Ito (dimensionless): 0.000619
 - iF in component Ito (dimensionless): 0.999872
 - iS in component Ito (dimensionless): 0.624018
 - ap in component Ito (dimensionless): 0.000315
 - iFp in component Ito (dimensionless): 0.999872
 - iSp in component Ito (dimensionless): 0.699384
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934783
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999887
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001612
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.327168
 - xs1 in component IKs (dimensionless): 0.241096
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997306
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
07:23:37 (20332): called boinc_finish(0)

</stderr_txt>
]]>