𝕏

Task 54835329

Name HuVeMOp_20240626114313200281_ORdGradInc_k_24-Schmidt_500-conf_396_1
Workunit 26036906
Created 26 Jun 2024, 9:48:56 UTC
Sent 26 Jun 2024, 14:24:20 UTC
Report deadline 29 Jun 2024, 14:24:20 UTC
Received 26 Jun 2024, 22:27:59 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 228779
Run time 1 hours 47 min 21 sec
CPU time 1 hours 40 min 49 sec
Validate state Valid
Credit 46.45
Device peak FLOPS 4.70 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.81 MB
Peak swap size 4.13 GB
Peak disk usage 0.18 MB

Stderr output

<core_client_version>7.16.21</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626114313200281_ORdGradInc_k_24-Schmidt_500-conf_396.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626114313200281_ORdGradInc_k_24-Schmidt_500-conf_396_1_r634084973_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626114313200281_ORdGradInc_k_24-Schmidt_500-conf_396_1_r634084973_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 109.367449
     * GNaL_b in INaL: 0.006830
     * Gto_b in Ito: 0.072090
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.032629
     * GKs_b in IKs: 0.001883
     * GK1_b in IK1: 0.160556
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 64.833553
     * GKb_b in IKb: 0.003798
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037451
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 6000.000000
     * CL_0 in membrane: 500.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499750000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 10923490, states[0] = -84.366241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 22731093, states[0] = -84.684162, states[40]= 0.000001
Saving checkpoint... 
Iteration: 33536762, states[0] = 24.344750, states[40]= 0.000008
Saving checkpoint... 
Iteration: 44777268, states[0] = 28.678198, states[40]= 0.000136
Saving checkpoint... 
Iteration: 55957657, states[0] = -84.608522, states[40]= 0.000001
Saving checkpoint... 
Iteration: 67109930, states[0] = -40.745935, states[40]= 0.000103
Saving checkpoint... 
Iteration: 78805792, states[0] = 13.454670, states[40]= 0.000029
Saving checkpoint... 
Iteration: 89463022, states[0] = -84.661476, states[40]= 0.000001
Saving checkpoint... 
Iteration: 100605675, states[0] = -36.337211, states[40]= 0.000134
Saving checkpoint... 
Iteration: 112573055, states[0] = 1.273600, states[40]= 0.000166
Saving checkpoint... 
Iteration: 123798962, states[0] = 17.378296, states[40]= 0.000011
Saving checkpoint... 
Iteration: 134683244, states[0] = -84.454608, states[40]= 0.000001
Saving checkpoint... 
Iteration: 144573692, states[0] = 0.678679, states[40]= 0.000172
Saving checkpoint... 
Iteration: 154510916, states[0] = 31.626213, states[40]= 0.048144
Saving checkpoint... 
Iteration: 164493944, states[0] = -84.811841, states[40]= 0.000001
Saving checkpoint... 
Iteration: 172600469, states[0] = -30.427267, states[40]= 0.000167
Saving checkpoint... 
Iteration: 181801311, states[0] = 15.997684, states[40]= 0.000015
Saving checkpoint... 
Iteration: 190689373, states[0] = -84.506126, states[40]= 0.000001
Saving checkpoint... 
Iteration: 200733190, states[0] = -84.768548, states[40]= 0.000001
Saving checkpoint... 
Iteration: 210732743, states[0] = -84.766334, states[40]= 0.000001
Saving checkpoint... 
Iteration: 221180475, states[0] = -84.428848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 230731112, states[0] = -84.758574, states[40]= 0.000001
Saving checkpoint... 
Iteration: 241555322, states[0] = 13.598372, states[40]= 0.000025
Saving checkpoint... 
Iteration: 250491066, states[0] = -84.798758, states[40]= 0.000001
Saving checkpoint... 
Iteration: 260046801, states[0] = 18.573529, states[40]= 0.000008
Saving checkpoint... 
Iteration: 269749868, states[0] = -84.829570, states[40]= 0.000001
Saving checkpoint... 
Iteration: 278936518, states[0] = -84.479654, states[40]= 0.000001
Saving checkpoint... 
Iteration: 288658461, states[0] = -84.148014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 299467125, states[0] = -84.687579, states[40]= 0.000001
Saving checkpoint... 
Iteration: 310780839, states[0] = 26.810194, states[40]= 0.000038
Saving checkpoint... 
Iteration: 322172544, states[0] = -84.348470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 332943326, states[0] = -84.532198, states[40]= 0.000001
Saving checkpoint... 
Iteration: 344771177, states[0] = 30.668452, states[40]= 0.001177
Saving checkpoint... 
Iteration: 356133919, states[0] = -71.431952, states[40]= 0.000003
Saving checkpoint... 
Iteration: 368553901, states[0] = 14.460862, states[40]= 0.000021
Saving checkpoint... 
Iteration: 380186209, states[0] = -84.473263, states[40]= 0.000001
Saving checkpoint... 
Iteration: 390999668, states[0] = -84.824458, states[40]= 0.000001
Saving checkpoint... 
Iteration: 402634243, states[0] = -71.871100, states[40]= 0.000002
Saving checkpoint... 
Iteration: 414599043, states[0] = -28.732158, states[40]= 0.000171
Saving checkpoint... 
Iteration: 426196287, states[0] = -84.550871, states[40]= 0.000001
Saving checkpoint... 
Iteration: 437613751, states[0] = -46.018379, states[40]= 0.000058
Saving checkpoint... 
Iteration: 448736624, states[0] = -84.773980, states[40]= 0.000001
Saving checkpoint... 
Iteration: 459901562, states[0] = -83.788482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 472121187, states[0] = -54.842864, states[40]= 0.000022
Saving checkpoint... 
Iteration: 483430230, states[0] = -84.416843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 494802906, states[0] = 15.057812, states[40]= 0.000019
Saving checkpoint... 
Iteration: 506483598, states[0] = -84.759246, states[40]= 0.000001
Saving checkpoint... 
Iteration: 517567657, states[0] = 5.414257, states[40]= 0.000100
Saving checkpoint... 
Iteration: 529496595, states[0] = -84.808779, states[40]= 0.000001
Saving checkpoint... 
Iteration: 541080417, states[0] = -5.850554, states[40]= 0.000236
Saving checkpoint... 
Iteration: 552728237, states[0] = -84.733787, states[40]= 0.000001
Saving checkpoint... 
Iteration: 564218236, states[0] = -84.683728, states[40]= 0.000001
Saving checkpoint... 
Iteration: 575700124, states[0] = -84.572658, states[40]= 0.000001
Saving checkpoint... 
Iteration: 587272568, states[0] = 30.221015, states[40]= 0.000715
Saving checkpoint... 
Iteration: 598117430, states[0] = -50.342241, states[40]= 0.000037
Saving checkpoint... 
Iteration: 609085512, states[0] = -11.876353, states[40]= 0.000216
Saving checkpoint... 
Iteration: 620784274, states[0] = 25.173197, states[40]= 0.000012
Saving checkpoint... 
Iteration: 632691003, states[0] = -84.502904, states[40]= 0.000001
Saving checkpoint... 
Iteration: 644269340, states[0] = 31.184808, states[40]= 0.002276
Saving checkpoint... 
Iteration: 656143738, states[0] = -81.692114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 668237842, states[0] = -84.770788, states[40]= 0.000001
Saving checkpoint... 
Iteration: 680385603, states[0] = -73.677816, states[40]= 0.000002
Saving checkpoint... 
Iteration: 692004006, states[0] = 32.649031, states[40]= 0.568675
Saving checkpoint... 
Iteration: 703533533, states[0] = 25.536135, states[40]= 0.000016
Saving checkpoint... 
Iteration: 715156983, states[0] = -84.088840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 726789548, states[0] = 22.500784, states[40]= 0.000005
Saving checkpoint... 
Iteration: 738546981, states[0] = 18.479672, states[40]= 0.000009
Saving checkpoint... 
Iteration: 749203255, states[0] = -84.587439, states[40]= 0.000001
Saving checkpoint... 
Iteration: 760899586, states[0] = -83.530463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 772086298, states[0] = -12.855353, states[40]= 0.000208
Saving checkpoint... 
Iteration: 783851035, states[0] = -31.093362, states[40]= 0.000164
Saving checkpoint... 
Iteration: 796311202, states[0] = 9.886957, states[40]= 0.000051
Saving checkpoint... 
Iteration: 807578428, states[0] = -3.740310, states[40]= 0.000224
Saving checkpoint... 
Iteration: 819762480, states[0] = 31.845795, states[40]= 0.027250
Saving checkpoint... 
Iteration: 831815398, states[0] = 7.040460, states[40]= 0.000080
Saving checkpoint... 
Iteration: 844212740, states[0] = -84.642761, states[40]= 0.000001
Saving checkpoint... 
Iteration: 855517855, states[0] = 31.517957, states[40]= 0.003886
Saving checkpoint... 
Iteration: 867327264, states[0] = -2.582180, states[40]= 0.000213
Saving checkpoint... 
Iteration: 878286583, states[0] = 24.026475, states[40]= 0.000007
Saving checkpoint... 
Iteration: 889961612, states[0] = -84.634475, states[40]= 0.000001
Saving checkpoint... 
Iteration: 901335181, states[0] = -11.449639, states[40]= 0.000219
Saving checkpoint... 
Iteration: 913146263, states[0] = -82.756764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 924353322, states[0] = -33.794233, states[40]= 0.000149
Saving checkpoint... 
Iteration: 934879054, states[0] = -64.737245, states[40]= 0.000006
Saving checkpoint... 
Iteration: 945924748, states[0] = -84.347137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 957888313, states[0] = -77.037766, states[40]= 0.000001
Saving checkpoint... 
Iteration: 969157538, states[0] = -84.095692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 981163007, states[0] = -84.208636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 992653076, states[0] = -83.889521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1004909264, states[0] = -84.138890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1017624337, states[0] = -58.666190, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1029743897, states[0] = -84.780642, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1041970271, states[0] = -84.676689, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1054577176, states[0] = -2.490610, states[40]= 0.000212
Saving checkpoint... 
Iteration: 1066477071, states[0] = -84.709336, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1078309529, states[0] = 10.978795, states[40]= 0.000042
Saving checkpoint... 
Iteration: 1090642372, states[0] = -80.807455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1103271812, states[0] = 30.479371, states[40]= 0.000936
Saving checkpoint... 
Iteration: 1116044156, states[0] = 20.046892, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1127475458, states[0] = -84.699415, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1140543801, states[0] = 20.240581, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1152998785, states[0] = -84.793393, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1165323084, states[0] = 1.191564, states[40]= 0.000162
Saving checkpoint... 
Iteration: 1177806978, states[0] = 12.592633, states[40]= 0.000031
Saving checkpoint... 
Iteration: 1190514422, states[0] = 31.913832, states[40]= 0.013453
Saving checkpoint... 
Iteration: 1203303900, states[0] = 14.474861, states[40]= 0.000021
Saving checkpoint... 
Iteration: 1216230347, states[0] = -84.718799, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1228905573, states[0] = -84.015823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1241052484, states[0] = 15.319975, states[40]= 0.000018
Saving checkpoint... 
Iteration: 1253773335, states[0] = 29.962249, states[40]= 0.000543
Saving checkpoint... 
Iteration: 1266184901, states[0] = -84.428768, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1279445518, states[0] = -84.513223, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1291561809, states[0] = 9.495484, states[40]= 0.000054
Saving checkpoint... 
Iteration: 1303948494, states[0] = -84.533945, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1317493874, states[0] = -84.769942, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1330331758, states[0] = -7.321900, states[40]= 0.000237
Saving checkpoint... 
Iteration: 1342545825, states[0] = 19.132720, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1355154437, states[0] = -83.956834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1367662719, states[0] = -84.189273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1380094830, states[0] = -23.568251, states[40]= 0.000166
Saving checkpoint... 
Iteration: 1392870711, states[0] = -54.206161, states[40]= 0.000023
Saving checkpoint... 
Iteration: 1405499687, states[0] = -84.787151, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1418652538, states[0] = -83.830260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1431356072, states[0] = -36.996714, states[40]= 0.000124
Saving checkpoint... 
Iteration: 1443423410, states[0] = -84.314833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1456468127, states[0] = -84.649993, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1468494783, states[0] = -84.767686, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1481121847, states[0] = -55.573181, states[40]= 0.000020
Saving checkpoint... 
Iteration: 1492664604, states[0] = -84.211923, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -84.660477
 - CaMKt in component CaMK (millimolar): 0.083657
 - cass in component intracellular_ions (millimolar): 0.000121
 - nai in component intracellular_ions (millimolar): 7.165305
 - nass in component intracellular_ions (millimolar): 7.165509
 - ki in component intracellular_ions (millimolar): 144.302235
 - kss in component intracellular_ions (millimolar): 144.302203
 - cansr in component intracellular_ions (millimolar): 2.496701
 - cajsr in component intracellular_ions (millimolar): 1.927334
 - cai in component intracellular_ions (millimolar): 0.000120
 - m in component INa (dimensionless): 0.010145
 - hf in component INa (dimensionless): 0.576800
 - hs in component INa (dimensionless): 0.576437
 - j in component INa (dimensionless): 0.574161
 - hsp in component INa (dimensionless): 0.328715
 - jp in component INa (dimensionless): 0.570380
 - mL in component INaL (dimensionless): 0.000347
 - hL in component INaL (dimensionless): 0.292535
 - hLp in component INaL (dimensionless): 0.122444
 - a in component Ito (dimensionless): 0.001244
 - iF in component Ito (dimensionless): 0.999215
 - iS in component Ito (dimensionless): 0.254088
 - ap in component Ito (dimensionless): 0.000634
 - iFp in component Ito (dimensionless): 0.999216
 - iSp in component Ito (dimensionless): 0.280953
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.782345
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.981503
 - jca in component ICaL (dimensionless): 0.986452
 - ffp in component ICaL (dimensionless): 0.999999
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.010790
 - xrf in component IKr (dimensionless): 0.006950
 - xrs in component IKr (dimensionless): 0.773440
 - xs1 in component IKs (dimensionless): 0.462620
 - xs2 in component IKs (dimensionless): 0.000352
 - xk1 in component IK1 (dimensionless): 0.996765
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
18:21:45 (55084): called boinc_finish(0)

</stderr_txt>
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