𝕏

Task 54835136

Name HuVeMOp_20240626114313200281_ORdGradInc_k_24-Drouin_MID_5000-conf_995_0
Workunit 26036810
Created 26 Jun 2024, 9:48:50 UTC
Sent 26 Jun 2024, 14:10:25 UTC
Report deadline 29 Jun 2024, 14:10:25 UTC
Received 1 Jul 2024, 7:26:36 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 236947
Run time 3 hours 15 min 45 sec
CPU time 2 hours 43 min 44 sec
Validate state Task was reported too late to validate
Credit 0.00
Device peak FLOPS 3.19 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.17 MB
Peak swap size 6.22 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626114313200281_ORdGradInc_k_24-Drouin_MID_5000-conf_995.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626114313200281_ORdGradInc_k_24-Drouin_MID_5000-conf_995_0_r975468748_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626114313200281_ORdGradInc_k_24-Drouin_MID_5000-conf_995_0_r975468748_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 96.659240
     * GNaL_b in INaL: 0.007410
     * Gto_b in Ito: 0.084175
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.031889
     * GKs_b in IKs: 0.001778
     * GK1_b in IK1: 0.171998
     * Gncx_b in INaCa_i: 0.000955
     * Pnak_b in INaK: 65.497112
     * GKb_b in IKb: 0.003909
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.050095
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 600.000000
     * CL_0 in membrane: 5000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 8856528, states[0] = -94.283422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 17065870, states[0] = -94.247412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25634667, states[0] = -94.159988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 34326777, states[0] = -94.238929, states[40]= 0.000001
Saving checkpoint... 
Iteration: 43299356, states[0] = -94.259987, states[40]= 0.000001
Saving checkpoint... 
Iteration: 51877141, states[0] = -94.248300, states[40]= 0.000001
Saving checkpoint... 
Iteration: 59977308, states[0] = -94.257823, states[40]= 0.000001
Saving checkpoint... 
Iteration: 68310539, states[0] = -94.295460, states[40]= 0.000001
Saving checkpoint... 
Iteration: 76566217, states[0] = -94.283491, states[40]= 0.000001
Saving checkpoint... 
Iteration: 84986387, states[0] = -94.276506, states[40]= 0.000001
Saving checkpoint... 
Iteration: 93714621, states[0] = -94.298924, states[40]= 0.000001
Saving checkpoint... 
Iteration: 101795873, states[0] = -94.288192, states[40]= 0.000001
Saving checkpoint... 
Iteration: 110451859, states[0] = -94.190937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 118949690, states[0] = -94.298026, states[40]= 0.000001
Saving checkpoint... 
Iteration: 127976478, states[0] = -94.221223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 136491922, states[0] = -94.299213, states[40]= 0.000001
Saving checkpoint... 
Iteration: 145025012, states[0] = 33.904657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 153812844, states[0] = -94.304925, states[40]= 0.000001
Saving checkpoint... 
Iteration: 162151512, states[0] = -94.291357, states[40]= 0.000001
Saving checkpoint... 
Iteration: 170915434, states[0] = -94.316372, states[40]= 0.000001
Saving checkpoint... 
Iteration: 179477678, states[0] = -94.293756, states[40]= 0.000001
Saving checkpoint... 
Iteration: 188154049, states[0] = -94.305353, states[40]= 0.000001
Saving checkpoint... 
Iteration: 197014238, states[0] = -94.293731, states[40]= 0.000001
Saving checkpoint... 
Iteration: 205327557, states[0] = -93.907498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 213644133, states[0] = -94.311334, states[40]= 0.000001
Saving checkpoint... 
Iteration: 222155027, states[0] = -94.292601, states[40]= 0.000001
Saving checkpoint... 
Iteration: 231182181, states[0] = -94.310284, states[40]= 0.000001
Saving checkpoint... 
Iteration: 239942465, states[0] = -94.290663, states[40]= 0.000001
Saving checkpoint... 
Iteration: 248479105, states[0] = -94.315962, states[40]= 0.000001
Saving checkpoint... 
Iteration: 257205081, states[0] = -94.292172, states[40]= 0.000001
Saving checkpoint... 
Iteration: 265808160, states[0] = -94.317339, states[40]= 0.000001
Saving checkpoint... 
Iteration: 275095586, states[0] = 17.748729, states[40]= 0.000007
Saving checkpoint... 
Iteration: 283887278, states[0] = -94.304526, states[40]= 0.000001
Saving checkpoint... 
Iteration: 292716466, states[0] = -29.104837, states[40]= 0.006563
Saving checkpoint... 
Iteration: 301291401, states[0] = -94.306892, states[40]= 0.000001
Saving checkpoint... 
Iteration: 310133808, states[0] = 3.881386, states[40]= 0.000171
Saving checkpoint... 
Iteration: 319074693, states[0] = -94.300102, states[40]= 0.000001
Saving checkpoint... 
Iteration: 326654053, states[0] = -94.298548, states[40]= 0.000001
Saving checkpoint... 
Iteration: 334007304, states[0] = -94.301369, states[40]= 0.000001
Saving checkpoint... 
Iteration: 342425042, states[0] = -94.290123, states[40]= 0.000001
Saving checkpoint... 
Iteration: 350477662, states[0] = -94.227434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 357406486, states[0] = -94.290094, states[40]= 0.000001
Saving checkpoint... 
Iteration: 365457139, states[0] = -94.206595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 373151788, states[0] = -94.304524, states[40]= 0.000001
Saving checkpoint... 
Iteration: 379760784, states[0] = -94.290825, states[40]= 0.000001
Saving checkpoint... 
Iteration: 385438934, states[0] = -94.184224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 393892466, states[0] = -94.303484, states[40]= 0.000001
Saving checkpoint... 
Iteration: 402218337, states[0] = -94.290940, states[40]= 0.000001
Saving checkpoint... 
Iteration: 410839681, states[0] = -94.316493, states[40]= 0.000001
Saving checkpoint... 
Iteration: 419291200, states[0] = -94.295490, states[40]= 0.000001
Saving checkpoint... 
Iteration: 427428446, states[0] = -94.289339, states[40]= 0.000001
Saving checkpoint... 
Iteration: 436079099, states[0] = -94.311810, states[40]= 0.000001
Saving checkpoint... 
Iteration: 444861294, states[0] = -94.289562, states[40]= 0.000001
Saving checkpoint... 
Iteration: 453226374, states[0] = -94.312394, states[40]= 0.000001
Saving checkpoint... 
Iteration: 461624388, states[0] = -94.297873, states[40]= 0.000001
Saving checkpoint... 
Iteration: 469992023, states[0] = -94.288625, states[40]= 0.000001
Saving checkpoint... 
Iteration: 478243511, states[0] = -94.313267, states[40]= 0.000001
Saving checkpoint... 
Iteration: 486703919, states[0] = -94.296241, states[40]= 0.000001
Saving checkpoint... 
Iteration: 495626286, states[0] = -94.298483, states[40]= 0.000001
Saving checkpoint... 
Iteration: 504529164, states[0] = -94.291714, states[40]= 0.000001
Saving checkpoint... 
Iteration: 512763992, states[0] = -60.633880, states[40]= 0.000121
Saving checkpoint... 
Iteration: 521179325, states[0] = -94.308094, states[40]= 0.000001
Saving checkpoint... 
Iteration: 529906020, states[0] = -94.288514, states[40]= 0.000001
Saving checkpoint... 
Iteration: 538329349, states[0] = -94.315255, states[40]= 0.000001
Saving checkpoint... 
Iteration: 546796996, states[0] = -94.294226, states[40]= 0.000001
Saving checkpoint... 
Iteration: 555604028, states[0] = -94.292480, states[40]= 0.000001
Saving checkpoint... 
Iteration: 564380028, states[0] = -94.292911, states[40]= 0.000001
Saving checkpoint... 
Iteration: 572994277, states[0] = -94.239390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 581639274, states[0] = -94.296489, states[40]= 0.000001
Saving checkpoint... 
Iteration: 590170505, states[0] = -12.940055, states[40]= 0.000801
Saving checkpoint... 
Iteration: 598595496, states[0] = -94.309832, states[40]= 0.000001
Saving checkpoint... 
Iteration: 606846690, states[0] = -94.292963, states[40]= 0.000001
Saving checkpoint... 
Iteration: 615521277, states[0] = -94.257497, states[40]= 0.000001
Saving checkpoint... 
Iteration: 623803330, states[0] = -94.303654, states[40]= 0.000001
Saving checkpoint... 
Iteration: 632555269, states[0] = 30.939649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641455114, states[0] = -94.299710, states[40]= 0.000001
Saving checkpoint... 
Iteration: 649800981, states[0] = -94.288050, states[40]= 0.000001
Saving checkpoint... 
Iteration: 658108235, states[0] = -94.292652, states[40]= 0.000001
Saving checkpoint... 
Iteration: 666787625, states[0] = -94.293251, states[40]= 0.000001
Saving checkpoint... 
Iteration: 675508660, states[0] = -94.248882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 683986946, states[0] = -94.298600, states[40]= 0.000001
Saving checkpoint... 
Iteration: 692584851, states[0] = 21.592205, states[40]= 0.000002
Saving checkpoint... 
Iteration: 701235364, states[0] = -94.304814, states[40]= 0.000001
Saving checkpoint... 
Iteration: 709675695, states[0] = -94.288437, states[40]= 0.000001
Saving checkpoint... 
Iteration: 718819124, states[0] = -94.302352, states[40]= 0.000001
Saving checkpoint... 
Iteration: 727228890, states[0] = -94.287849, states[40]= 0.000001
Saving checkpoint... 
Iteration: 735981192, states[0] = -94.311667, states[40]= 0.000001
Saving checkpoint... 
Iteration: 744722914, states[0] = -94.287734, states[40]= 0.000001
Saving checkpoint... 
Iteration: 753557180, states[0] = -94.309499, states[40]= 0.000001
Saving checkpoint... 
Iteration: 761843145, states[0] = -94.291575, states[40]= 0.000001
Saving checkpoint... 
Iteration: 770115361, states[0] = 10.572405, states[40]= 0.000041
Saving checkpoint... 
Iteration: 778208783, states[0] = -94.307968, states[40]= 0.000001
Saving checkpoint... 
Iteration: 786939134, states[0] = -94.290106, states[40]= 0.000001
Saving checkpoint... 
Iteration: 795578544, states[0] = -94.282374, states[40]= 0.000001
Saving checkpoint... 
Iteration: 804719424, states[0] = -94.287203, states[40]= 0.000001
Saving checkpoint... 
Iteration: 813470490, states[0] = -94.311198, states[40]= 0.000001
Saving checkpoint... 
Iteration: 822012531, states[0] = -94.288946, states[40]= 0.000001
Saving checkpoint... 
Iteration: 830800001, states[0] = -94.312129, states[40]= 0.000001
Saving checkpoint... 
Iteration: 839911769, states[0] = -94.285605, states[40]= 0.000001
Saving checkpoint... 
Iteration: 848761285, states[0] = -94.302719, states[40]= 0.000001
Saving checkpoint... 
Iteration: 857883991, states[0] = -94.081977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 866904468, states[0] = -94.289791, states[40]= 0.000001
Saving checkpoint... 
Iteration: 875638311, states[0] = -94.297438, states[40]= 0.000001
Saving checkpoint... 
Iteration: 883861343, states[0] = -94.299727, states[40]= 0.000001
Saving checkpoint... 
Iteration: 892520258, states[0] = 33.161268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 901088406, states[0] = -94.307236, states[40]= 0.000001
Saving checkpoint... 
Iteration: 909481833, states[0] = -94.288472, states[40]= 0.000001
Saving checkpoint... 
Iteration: 918352184, states[0] = -94.311823, states[40]= 0.000001
Saving checkpoint... 
Iteration: 926724946, states[0] = -94.291814, states[40]= 0.000001
Saving checkpoint... 
Iteration: 935187942, states[0] = -20.531453, states[40]= 0.003676
Saving checkpoint... 
Iteration: 943368229, states[0] = -94.311553, states[40]= 0.000001
Saving checkpoint... 
Iteration: 951875891, states[0] = -94.289371, states[40]= 0.000001
Saving checkpoint... 
Iteration: 960467967, states[0] = -94.212500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 968477220, states[0] = -94.309606, states[40]= 0.000001
Saving checkpoint... 
Iteration: 977415081, states[0] = -94.284311, states[40]= 0.000001
Saving checkpoint... 
Iteration: 986038941, states[0] = -94.307853, states[40]= 0.000001
Saving checkpoint... 
Iteration: 994809442, states[0] = -94.284790, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1003557147, states[0] = -94.307182, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1012391199, states[0] = -94.284120, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1020899737, states[0] = -94.310560, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1029651246, states[0] = -94.285675, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1038437380, states[0] = -94.309806, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1046752544, states[0] = -94.290262, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1055319604, states[0] = -93.867123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1063919653, states[0] = -94.296622, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1073119493, states[0] = -94.291590, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1081444204, states[0] = -94.295881, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1090024146, states[0] = 33.772139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1098734759, states[0] = -94.301147, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1107217666, states[0] = -94.284409, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1116326845, states[0] = -94.298463, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1124910895, states[0] = -94.282964, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1133615478, states[0] = -94.304291, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1142146789, states[0] = -94.284670, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1150604542, states[0] = -94.287099, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1159764914, states[0] = -94.283568, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1168195286, states[0] = -94.303042, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1176669455, states[0] = -94.290433, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1185199227, states[0] = -23.632274, states[40]= 0.006292
Saving checkpoint... 
Iteration: 1193626685, states[0] = -94.303408, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1202694559, states[0] = -22.381752, states[40]= 0.005417
Saving checkpoint... 
Iteration: 1211139726, states[0] = -94.302863, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1219344153, states[0] = -94.287318, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1227938068, states[0] = -94.175193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1236506315, states[0] = -94.293056, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1245491940, states[0] = -94.231288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1254584902, states[0] = -94.284198, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1263116871, states[0] = -94.289208, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1271737765, states[0] = -94.288410, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1280623259, states[0] = -94.290533, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1288835937, states[0] = -94.296629, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1297198665, states[0] = -94.282798, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1305707922, states[0] = -94.303004, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1314544719, states[0] = -94.284040, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1323105522, states[0] = -94.285765, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1331545811, states[0] = -94.291344, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1340375716, states[0] = -94.057288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1349291255, states[0] = -94.286869, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1357834865, states[0] = -93.927876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1366629176, states[0] = -94.289396, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1375270753, states[0] = -67.499564, states[40]= 0.000042
Saving checkpoint... 
Iteration: 1384172833, states[0] = -94.288451, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1392609013, states[0] = 12.873839, states[40]= 0.000023
Saving checkpoint... 
Iteration: 1401057078, states[0] = -94.303504, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1409761994, states[0] = -94.281271, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1418157024, states[0] = -94.295712, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1426769518, states[0] = -94.286476, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1435154984, states[0] = -4.759054, states[40]= 0.000552
Saving checkpoint... 
Iteration: 1443645711, states[0] = -94.300534, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1452432413, states[0] = -94.279811, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1461028854, states[0] = -94.303732, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1469622941, states[0] = -94.281846, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1478223162, states[0] = -94.302666, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1486737762, states[0] = -94.286417, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1495232746, states[0] = -37.161655, states[40]= 0.003236
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.155006
 - CaMKt in component CaMK (millimolar): 0.001826
 - cass in component intracellular_ions (millimolar): 0.000096
 - nai in component intracellular_ions (millimolar): 7.936150
 - nass in component intracellular_ions (millimolar): 7.936302
 - ki in component intracellular_ions (millimolar): 143.873943
 - kss in component intracellular_ions (millimolar): 143.873928
 - cansr in component intracellular_ions (millimolar): 1.803949
 - cajsr in component intracellular_ions (millimolar): 1.805486
 - cai in component intracellular_ions (millimolar): 0.000101
 - m in component INa (dimensionless): 0.003902
 - hf in component INa (dimensionless): 0.866424
 - hs in component INa (dimensionless): 0.866424
 - j in component INa (dimensionless): 0.866426
 - hsp in component INa (dimensionless): 0.700773
 - jp in component INa (dimensionless): 0.866426
 - mL in component INaL (dimensionless): 0.000057
 - hL in component INaL (dimensionless): 0.709036
 - hLp in component INaL (dimensionless): 0.515540
 - a in component Ito (dimensionless): 0.000656
 - iF in component Ito (dimensionless): 0.999851
 - iS in component Ito (dimensionless): 0.997181
 - ap in component Ito (dimensionless): 0.000334
 - iFp in component Ito (dimensionless): 0.999851
 - iSp in component Ito (dimensionless): 0.999029
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998004
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004445
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.002431
 - xs1 in component IKs (dimensionless): 0.032881
 - xs2 in component IKs (dimensionless): 0.000095
 - xk1 in component IK1 (dimensionless): 0.997526
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
22:10:45 (10572): called boinc_finish(0)

</stderr_txt>
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