𝕏

Task 54835125

Name HuVeMOp_20240626114313200281_ORdGradInc_k_24-Drouin_MID_3000-conf_95_1
Workunit 26036804
Created 26 Jun 2024, 9:48:45 UTC
Sent 26 Jun 2024, 14:10:25 UTC
Report deadline 29 Jun 2024, 14:10:25 UTC
Received 1 Jul 2024, 7:26:48 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 236947
Run time 3 hours 15 min 53 sec
CPU time 2 hours 43 min 33 sec
Validate state Task was reported too late to validate
Credit 0.00
Device peak FLOPS 3.19 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.18 MB
Peak swap size 6.22 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626114313200281_ORdGradInc_k_24-Drouin_MID_3000-conf_95.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626114313200281_ORdGradInc_k_24-Drouin_MID_3000-conf_95_1_r1913972795_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626114313200281_ORdGradInc_k_24-Drouin_MID_3000-conf_95_1_r1913972795_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 113.557633
     * GNaL_b in INaL: 0.007117
     * Gto_b in Ito: 0.092502
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032271
     * GKs_b in IKs: 0.001772
     * GK1_b in IK1: 0.154515
     * Gncx_b in INaCa_i: 0.000957
     * Pnak_b in INaK: 68.235588
     * GKb_b in IKb: 0.003770
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.050968
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 8668061, states[0] = -94.146333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 17254038, states[0] = -94.136270, states[40]= 0.000001
Saving checkpoint... 
Iteration: 26036477, states[0] = -94.087230, states[40]= 0.000001
Saving checkpoint... 
Iteration: 34343544, states[0] = -94.131168, states[40]= 0.000001
Saving checkpoint... 
Iteration: 43099630, states[0] = -94.152636, states[40]= 0.000001
Saving checkpoint... 
Iteration: 51497303, states[0] = -94.096573, states[40]= 0.000001
Saving checkpoint... 
Iteration: 60098958, states[0] = 16.516453, states[40]= 0.000018
Saving checkpoint... 
Iteration: 68796937, states[0] = -94.171118, states[40]= 0.000001
Saving checkpoint... 
Iteration: 77247412, states[0] = -94.195224, states[40]= 0.000001
Saving checkpoint... 
Iteration: 86026888, states[0] = -94.150902, states[40]= 0.000001
Saving checkpoint... 
Iteration: 94704096, states[0] = -29.876706, states[40]= 0.007220
Saving checkpoint... 
Iteration: 103596028, states[0] = 16.769896, states[40]= 0.000017
Saving checkpoint... 
Iteration: 112135957, states[0] = -94.200674, states[40]= 0.000001
Saving checkpoint... 
Iteration: 120680977, states[0] = -94.209537, states[40]= 0.000001
Saving checkpoint... 
Iteration: 129007899, states[0] = 26.644413, states[40]= -0.000000
Saving checkpoint... 
Iteration: 137513568, states[0] = -94.211455, states[40]= 0.000001
Saving checkpoint... 
Iteration: 146111452, states[0] = -94.202340, states[40]= 0.000001
Saving checkpoint... 
Iteration: 154465308, states[0] = -94.194912, states[40]= 0.000001
Saving checkpoint... 
Iteration: 163094235, states[0] = -94.210349, states[40]= 0.000001
Saving checkpoint... 
Iteration: 171200158, states[0] = -29.887704, states[40]= 0.006969
Saving checkpoint... 
Iteration: 179409373, states[0] = -94.218916, states[40]= 0.000001
Saving checkpoint... 
Iteration: 187794822, states[0] = -93.629252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 195839391, states[0] = -94.221156, states[40]= 0.000001
Saving checkpoint... 
Iteration: 204686984, states[0] = -94.217164, states[40]= 0.000001
Saving checkpoint... 
Iteration: 213004360, states[0] = 20.790291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 221550027, states[0] = -94.213663, states[40]= 0.000001
Saving checkpoint... 
Iteration: 230299868, states[0] = -94.221630, states[40]= 0.000001
Saving checkpoint... 
Iteration: 238725656, states[0] = -45.620463, states[40]= 0.001438
Saving checkpoint... 
Iteration: 247410443, states[0] = -94.198564, states[40]= 0.000001
Saving checkpoint... 
Iteration: 255982364, states[0] = -94.216358, states[40]= 0.000001
Saving checkpoint... 
Iteration: 264826768, states[0] = -94.221094, states[40]= 0.000001
Saving checkpoint... 
Iteration: 273524931, states[0] = -94.171405, states[40]= 0.000001
Saving checkpoint... 
Iteration: 282139998, states[0] = -1.407304, states[40]= 0.000615
Saving checkpoint... 
Iteration: 290494500, states[0] = -94.215326, states[40]= 0.000001
Saving checkpoint... 
Iteration: 298868033, states[0] = -93.948870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 307262113, states[0] = -94.203301, states[40]= 0.000001
Saving checkpoint... 
Iteration: 316154771, states[0] = -94.207724, states[40]= 0.000001
Saving checkpoint... 
Iteration: 324996206, states[0] = -94.214649, states[40]= 0.000001
Saving checkpoint... 
Iteration: 333428497, states[0] = -94.076487, states[40]= 0.000001
Saving checkpoint... 
Iteration: 341914713, states[0] = -94.196887, states[40]= 0.000001
Saving checkpoint... 
Iteration: 350226277, states[0] = -94.218172, states[40]= 0.000001
Saving checkpoint... 
Iteration: 359036263, states[0] = -94.176113, states[40]= 0.000001
Saving checkpoint... 
Iteration: 367426203, states[0] = -94.196008, states[40]= 0.000001
Saving checkpoint... 
Iteration: 375663399, states[0] = -94.212256, states[40]= 0.000001
Saving checkpoint... 
Iteration: 384057645, states[0] = 29.511099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 393088870, states[0] = 19.087720, states[40]= 0.000009
Saving checkpoint... 
Iteration: 401666504, states[0] = -94.205595, states[40]= 0.000001
Saving checkpoint... 
Iteration: 410532147, states[0] = -94.211448, states[40]= 0.000001
Saving checkpoint... 
Iteration: 419471222, states[0] = -94.213912, states[40]= 0.000001
Saving checkpoint... 
Iteration: 428049875, states[0] = -94.181366, states[40]= 0.000001
Saving checkpoint... 
Iteration: 436430492, states[0] = -94.194533, states[40]= 0.000001
Saving checkpoint... 
Iteration: 445072368, states[0] = -94.208975, states[40]= 0.000001
Saving checkpoint... 
Iteration: 453316028, states[0] = -93.745703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 462067027, states[0] = 26.750801, states[40]= 0.000001
Saving checkpoint... 
Iteration: 470979719, states[0] = -94.192231, states[40]= 0.000001
Saving checkpoint... 
Iteration: 479514000, states[0] = -94.210920, states[40]= 0.000001
Saving checkpoint... 
Iteration: 488034816, states[0] = -94.172868, states[40]= 0.000001
Saving checkpoint... 
Iteration: 496668709, states[0] = -17.253099, states[40]= 0.001812
Saving checkpoint... 
Iteration: 505278943, states[0] = -94.198841, states[40]= 0.000001
Saving checkpoint... 
Iteration: 513945116, states[0] = -94.213137, states[40]= 0.000001
Saving checkpoint... 
Iteration: 522720634, states[0] = -94.214549, states[40]= 0.000001
Saving checkpoint... 
Iteration: 531343141, states[0] = -93.862376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 539906686, states[0] = -94.193352, states[40]= 0.000001
Saving checkpoint... 
Iteration: 548890649, states[0] = -94.193746, states[40]= 0.000001
Saving checkpoint... 
Iteration: 557469880, states[0] = -94.211298, states[40]= 0.000001
Saving checkpoint... 
Iteration: 566091068, states[0] = -94.193852, states[40]= 0.000001
Saving checkpoint... 
Iteration: 574381759, states[0] = -94.193572, states[40]= 0.000001
Saving checkpoint... 
Iteration: 582694629, states[0] = -94.211569, states[40]= 0.000001
Saving checkpoint... 
Iteration: 591285738, states[0] = -93.555500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599863803, states[0] = -94.193735, states[40]= 0.000001
Saving checkpoint... 
Iteration: 608288712, states[0] = -94.214803, states[40]= 0.000001
Saving checkpoint... 
Iteration: 616660086, states[0] = -12.354065, states[40]= 0.001058
Saving checkpoint... 
Iteration: 625319815, states[0] = -94.194901, states[40]= 0.000001
Saving checkpoint... 
Iteration: 633851586, states[0] = -94.213743, states[40]= 0.000001
Saving checkpoint... 
Iteration: 641910447, states[0] = -94.191243, states[40]= 0.000001
Saving checkpoint... 
Iteration: 650233597, states[0] = -94.212724, states[40]= 0.000001
Saving checkpoint... 
Iteration: 658927206, states[0] = -94.068177, states[40]= 0.000001
Saving checkpoint... 
Iteration: 667631327, states[0] = 2.415771, states[40]= 0.000365
Saving checkpoint... 
Iteration: 676272851, states[0] = -94.195774, states[40]= 0.000001
Saving checkpoint... 
Iteration: 684552769, states[0] = -94.177674, states[40]= 0.000001
Saving checkpoint... 
Iteration: 693374651, states[0] = -93.959553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 701835195, states[0] = -94.192828, states[40]= 0.000001
Saving checkpoint... 
Iteration: 710122710, states[0] = -94.198979, states[40]= 0.000001
Saving checkpoint... 
Iteration: 718793470, states[0] = -93.613115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 727134494, states[0] = -94.200713, states[40]= 0.000001
Saving checkpoint... 
Iteration: 735506129, states[0] = -94.150626, states[40]= 0.000001
Saving checkpoint... 
Iteration: 744133758, states[0] = 1.381977, states[40]= 0.000428
Saving checkpoint... 
Iteration: 752834109, states[0] = -94.191880, states[40]= 0.000001
Saving checkpoint... 
Iteration: 761391257, states[0] = -94.210242, states[40]= 0.000001
Saving checkpoint... 
Iteration: 770334438, states[0] = -94.211408, states[40]= 0.000001
Saving checkpoint... 
Iteration: 778613000, states[0] = 9.799534, states[40]= 0.000089
Saving checkpoint... 
Iteration: 787628241, states[0] = 3.702687, states[40]= 0.000295
Saving checkpoint... 
Iteration: 795899860, states[0] = -94.209301, states[40]= 0.000001
Saving checkpoint... 
Iteration: 804242615, states[0] = -58.912169, states[40]= 0.000216
Saving checkpoint... 
Iteration: 813127649, states[0] = 3.946582, states[40]= 0.000282
Saving checkpoint... 
Iteration: 821967599, states[0] = -94.185816, states[40]= 0.000001
Saving checkpoint... 
Iteration: 830813326, states[0] = -94.191169, states[40]= 0.000001
Saving checkpoint... 
Iteration: 839689913, states[0] = -94.196089, states[40]= 0.000001
Saving checkpoint... 
Iteration: 848401994, states[0] = -94.208220, states[40]= 0.000001
Saving checkpoint... 
Iteration: 856864599, states[0] = -93.927936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 864913895, states[0] = -94.207503, states[40]= 0.000001
Saving checkpoint... 
Iteration: 873499181, states[0] = -94.142927, states[40]= 0.000001
Saving checkpoint... 
Iteration: 881893145, states[0] = -94.187209, states[40]= 0.000001
Saving checkpoint... 
Iteration: 890079018, states[0] = -94.183787, states[40]= 0.000001
Saving checkpoint... 
Iteration: 898783037, states[0] = -93.513581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 907530052, states[0] = 33.332318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 916237038, states[0] = -94.192604, states[40]= 0.000001
Saving checkpoint... 
Iteration: 925016286, states[0] = -94.202198, states[40]= 0.000001
Saving checkpoint... 
Iteration: 933730181, states[0] = -94.207088, states[40]= 0.000001
Saving checkpoint... 
Iteration: 942527381, states[0] = -94.159997, states[40]= 0.000001
Saving checkpoint... 
Iteration: 951012647, states[0] = 29.787111, states[40]= -0.000000
Saving checkpoint... 
Iteration: 959353942, states[0] = -94.207397, states[40]= 0.000001
Saving checkpoint... 
Iteration: 968163716, states[0] = -94.200835, states[40]= 0.000001
Saving checkpoint... 
Iteration: 977225381, states[0] = -94.206009, states[40]= 0.000001
Saving checkpoint... 
Iteration: 985763691, states[0] = -83.859918, states[40]= 0.000005
Saving checkpoint... 
Iteration: 994222701, states[0] = -94.191695, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1002535524, states[0] = -94.163254, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1010550229, states[0] = -94.199027, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1018582319, states[0] = 21.507033, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1026776603, states[0] = -94.206601, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1035332729, states[0] = -93.810939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1043522982, states[0] = -94.199605, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1052053274, states[0] = -94.170768, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1060356573, states[0] = -94.185081, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1069222869, states[0] = -94.190234, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1077669759, states[0] = -94.199461, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1086245343, states[0] = -61.205220, states[40]= 0.000152
Saving checkpoint... 
Iteration: 1094596029, states[0] = -94.195330, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1103439493, states[0] = -94.201943, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1111714409, states[0] = -37.896556, states[40]= 0.003566
Saving checkpoint... 
Iteration: 1120002900, states[0] = -94.199004, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1128360563, states[0] = -93.910274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1136955925, states[0] = -94.180100, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1145680212, states[0] = -94.190587, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1154095782, states[0] = -94.183812, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1162772232, states[0] = -92.382629, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1171732169, states[0] = -50.604626, states[40]= 0.000735
Saving checkpoint... 
Iteration: 1179844063, states[0] = -94.203324, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1188457607, states[0] = -94.098210, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1196509879, states[0] = -94.197217, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1204945061, states[0] = -94.082717, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1213813821, states[0] = -93.719308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1222715200, states[0] = -38.393544, states[40]= 0.003382
Saving checkpoint... 
Iteration: 1231499081, states[0] = -94.176870, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1240368978, states[0] = -94.181131, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1248826529, states[0] = -94.202257, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1256901916, states[0] = -94.179625, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1265248430, states[0] = -94.201378, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1273791917, states[0] = -93.591610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1282467502, states[0] = -94.176895, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1291240586, states[0] = -94.185188, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1299682394, states[0] = -94.196553, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1308097111, states[0] = 15.974255, states[40]= 0.000021
Saving checkpoint... 
Iteration: 1316897014, states[0] = -94.178634, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1325070823, states[0] = -94.172476, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1333580600, states[0] = 22.130221, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1342530541, states[0] = 33.346989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1351506363, states[0] = 24.991056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1360494561, states[0] = -94.174521, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1368933835, states[0] = -94.197026, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1377404293, states[0] = -94.014226, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1385980253, states[0] = -94.174485, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1394139532, states[0] = -94.188952, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1402419340, states[0] = -94.176201, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1410917331, states[0] = -94.196815, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1419405302, states[0] = -94.015370, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1427555537, states[0] = -94.190718, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1435992194, states[0] = -94.126571, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1444263298, states[0] = -94.181290, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1452920062, states[0] = -94.195905, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1461490308, states[0] = -94.124548, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1469771992, states[0] = -94.180442, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1478621955, states[0] = -94.186728, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1486693550, states[0] = -27.266061, states[40]= 0.007454
Saving checkpoint... 
Iteration: 1495144482, states[0] = -94.185400, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.047602
 - CaMKt in component CaMK (millimolar): 0.004658
 - cass in component intracellular_ions (millimolar): 0.000100
 - nai in component intracellular_ions (millimolar): 8.053949
 - nass in component intracellular_ions (millimolar): 8.054118
 - ki in component intracellular_ions (millimolar): 143.646332
 - kss in component intracellular_ions (millimolar): 143.646312
 - cansr in component intracellular_ions (millimolar): 1.966256
 - cajsr in component intracellular_ions (millimolar): 1.968753
 - cai in component intracellular_ions (millimolar): 0.000106
 - m in component INa (dimensionless): 0.003944
 - hf in component INa (dimensionless): 0.864369
 - hs in component INa (dimensionless): 0.864370
 - j in component INa (dimensionless): 0.864378
 - hsp in component INa (dimensionless): 0.697066
 - jp in component INa (dimensionless): 0.864382
 - mL in component INaL (dimensionless): 0.000058
 - hL in component INaL (dimensionless): 0.706147
 - hLp in component INaL (dimensionless): 0.507312
 - a in component Ito (dimensionless): 0.000660
 - iF in component Ito (dimensionless): 0.999849
 - iS in component Ito (dimensionless): 0.963904
 - ap in component Ito (dimensionless): 0.000336
 - iFp in component Ito (dimensionless): 0.999849
 - iSp in component Ito (dimensionless): 0.981088
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.985705
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005159
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.034458
 - xs1 in component IKs (dimensionless): 0.093494
 - xs2 in component IKs (dimensionless): 0.000097
 - xk1 in component IK1 (dimensionless): 0.997553
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
08:01:40 (3544): called boinc_finish(0)

</stderr_txt>
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