𝕏

Task 54835111

Name HuVeMOp_20240626114313200281_ORdGradInc_k_24-Drouin_EPI_5000-conf_395_1
Workunit 26036797
Created 26 Jun 2024, 9:48:45 UTC
Sent 26 Jun 2024, 14:10:25 UTC
Report deadline 29 Jun 2024, 14:10:25 UTC
Received 1 Jul 2024, 7:26:48 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 236947
Run time 3 hours 17 min 47 sec
CPU time 2 hours 45 min 23 sec
Validate state Task was reported too late to validate
Credit 0.00
Device peak FLOPS 3.19 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.18 MB
Peak swap size 6.22 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626114313200281_ORdGradInc_k_24-Drouin_EPI_5000-conf_395.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626114313200281_ORdGradInc_k_24-Drouin_EPI_5000-conf_395_1_r458422558_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626114313200281_ORdGradInc_k_24-Drouin_EPI_5000-conf_395_1_r458422558_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 99.457330
     * GNaL_b in INaL: 0.005534
     * Gto_b in Ito: 0.067653
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.031981
     * GKs_b in IKs: 0.001793
     * GK1_b in IK1: 0.147970
     * Gncx_b in INaCa_i: 0.000970
     * Pnak_b in INaK: 69.261748
     * GKb_b in IKb: 0.004003
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.044371
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 600.000000
     * CL_0 in membrane: 5000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 8445365, states[0] = -94.159870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 17021561, states[0] = -94.068530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25951045, states[0] = -94.058508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 34321348, states[0] = -94.016821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 42601652, states[0] = 3.424309, states[40]= 0.000049
Saving checkpoint... 
Iteration: 50978647, states[0] = -94.035585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59731290, states[0] = -94.002958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 68566152, states[0] = -94.034741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 76523355, states[0] = -94.020512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84810256, states[0] = -94.008891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 93467555, states[0] = -94.046732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 102237767, states[0] = -94.014112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 110625108, states[0] = -94.061271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 119180726, states[0] = -94.026494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 128023076, states[0] = -94.051932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 136601844, states[0] = -94.030436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 145091059, states[0] = 8.658915, states[40]= 0.000028
Saving checkpoint... 
Iteration: 153730440, states[0] = -94.043335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 161968492, states[0] = -94.024748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170151820, states[0] = -48.439953, states[40]= 0.000077
Saving checkpoint... 
Iteration: 178643644, states[0] = -94.047891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 187042832, states[0] = -94.024361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 195398710, states[0] = -93.991190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 203380901, states[0] = -94.060942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 211816711, states[0] = -94.028505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 219980361, states[0] = -94.019441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 228733069, states[0] = -94.044767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 236849943, states[0] = -94.027926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 245104864, states[0] = -0.091739, states[40]= 0.000112
Saving checkpoint... 
Iteration: 253412732, states[0] = -94.059405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 261923000, states[0] = -94.026546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 270232985, states[0] = -93.498052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 278615692, states[0] = -94.049471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 287138473, states[0] = -94.023120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 295564293, states[0] = -94.062379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 303977643, states[0] = -94.036232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 312658475, states[0] = -55.905995, states[40]= 0.000032
Saving checkpoint... 
Iteration: 320859623, states[0] = -94.061645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 329469705, states[0] = -94.025316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 337566832, states[0] = 20.146364, states[40]= 0.000001
Saving checkpoint... 
Iteration: 346231574, states[0] = -94.044160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 354785997, states[0] = -94.020762, states[40]= 0.000000
Saving checkpoint... 
Iteration: 363560342, states[0] = -94.051362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 372398741, states[0] = -94.019386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 381181398, states[0] = -94.045883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 389738381, states[0] = -94.021041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 398254066, states[0] = -94.065628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 407136934, states[0] = -94.022199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 415566242, states[0] = -94.061670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 424024638, states[0] = -94.033954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432314266, states[0] = -94.019798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 440671522, states[0] = -94.066873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 449143051, states[0] = -94.030747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 457415145, states[0] = -94.018510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 466030951, states[0] = -94.051907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474044488, states[0] = -94.033003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 482383646, states[0] = -94.018625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 491038742, states[0] = -94.051325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 499265057, states[0] = -94.027646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 507621302, states[0] = -15.223803, states[40]= 0.000163
Saving checkpoint... 
Iteration: 516256450, states[0] = -94.041796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 524884572, states[0] = -94.018259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 533598417, states[0] = -94.048194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 542019492, states[0] = -94.022765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 550296254, states[0] = -93.798712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 558946917, states[0] = -94.035036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 566903044, states[0] = -94.024467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 575686037, states[0] = -94.065694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 584039052, states[0] = -94.032224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 592612658, states[0] = -6.458433, states[40]= 0.000170
Saving checkpoint... 
Iteration: 601315662, states[0] = -94.038930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 609978253, states[0] = -94.016609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 618426241, states[0] = -94.055834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 627006677, states[0] = -94.022249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 635481657, states[0] = -94.040324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 643769290, states[0] = -94.040246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 652223286, states[0] = -94.019024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 660738134, states[0] = -94.063948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 668957258, states[0] = -94.033806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 677465807, states[0] = -94.016161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685533056, states[0] = -94.054175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 693472518, states[0] = -94.052872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 701969621, states[0] = -94.022210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 709920059, states[0] = -94.016339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 718561253, states[0] = -94.048353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 726537876, states[0] = -94.031059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 735047558, states[0] = 26.138278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 743752191, states[0] = -94.040049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 752121448, states[0] = -94.019515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 760615283, states[0] = -94.062888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 769110953, states[0] = -94.028832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 777887778, states[0] = -93.975819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 786246312, states[0] = -94.039916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 795035742, states[0] = 27.812601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 803163307, states[0] = -94.063811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 811462706, states[0] = -94.032449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 819755047, states[0] = -94.017230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 828510184, states[0] = -94.049877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 837255491, states[0] = -94.017078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 845456584, states[0] = -94.027664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 853952354, states[0] = -94.032398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 862237502, states[0] = -94.017085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 870574647, states[0] = -94.058835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 879048606, states[0] = -94.029494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 887199093, states[0] = -94.017352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 895568589, states[0] = -94.057940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 904357198, states[0] = -94.022455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 912752408, states[0] = -93.610272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 921493632, states[0] = -94.030637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 930444337, states[0] = -94.020357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 938880610, states[0] = -94.033909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 947225843, states[0] = -94.016513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 955690791, states[0] = -94.062472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 963857288, states[0] = -94.034465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 972447095, states[0] = -94.013863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 981317086, states[0] = -94.035692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 989630335, states[0] = -94.017397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 997911302, states[0] = -93.996637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1006410137, states[0] = -94.032403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1014901630, states[0] = -94.013963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1023739948, states[0] = -94.038168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1032089881, states[0] = -94.017604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1040904159, states[0] = -94.053414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1049154669, states[0] = -94.025437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1057940494, states[0] = -94.017020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1066455432, states[0] = -94.030523, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1074820743, states[0] = -94.014326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1083009209, states[0] = -94.045344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1091257210, states[0] = -94.036944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1099755715, states[0] = -94.014868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1108223502, states[0] = -94.060606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1116767735, states[0] = -94.022405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1124999874, states[0] = -94.012076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1133359441, states[0] = -94.054879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1141845575, states[0] = -94.020675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1149955269, states[0] = -94.012291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1157949171, states[0] = -94.021164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1166567458, states[0] = -94.026588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1175134475, states[0] = -29.276193, states[40]= 0.000278
Saving checkpoint... 
Iteration: 1183755178, states[0] = -94.036245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1191831811, states[0] = -94.020514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1200583039, states[0] = -94.056920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1209012120, states[0] = -94.027708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1217078402, states[0] = -94.016214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1225707284, states[0] = -94.059975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1234041533, states[0] = -94.026701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1242252029, states[0] = -94.013715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1250638847, states[0] = -94.059678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1259486052, states[0] = -94.017260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1267838459, states[0] = -93.898840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1276423522, states[0] = -94.029722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1284930735, states[0] = -94.011398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1293613321, states[0] = -94.041154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1301728168, states[0] = -94.021677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1310025384, states[0] = 27.599133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1318790796, states[0] = -94.033796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1327507469, states[0] = 20.293502, states[40]= 0.000602
Saving checkpoint... 
Iteration: 1336194655, states[0] = -94.037337, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1345038536, states[0] = 27.586224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1353454124, states[0] = -94.048267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1362046700, states[0] = -94.015462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1369846831, states[0] = -94.011559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1378474584, states[0] = -94.047030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1386393438, states[0] = -94.029741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1394581125, states[0] = -94.014683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1403124789, states[0] = -94.057940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1411873560, states[0] = -94.017893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1420446359, states[0] = -94.017402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1429106800, states[0] = -94.023392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437743127, states[0] = -93.552596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1446129788, states[0] = -94.039149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1454694485, states[0] = -94.012641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1462803502, states[0] = -93.813207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1471460397, states[0] = -94.026977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1480413949, states[0] = -93.994778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1488995023, states[0] = -94.025834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497182267, states[0] = -94.012441, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.884897
 - CaMKt in component CaMK (millimolar): 0.001673
 - cass in component intracellular_ions (millimolar): 0.000100
 - nai in component intracellular_ions (millimolar): 7.103897
 - nass in component intracellular_ions (millimolar): 7.104031
 - ki in component intracellular_ions (millimolar): 144.609721
 - kss in component intracellular_ions (millimolar): 144.609708
 - cansr in component intracellular_ions (millimolar): 2.368347
 - cajsr in component intracellular_ions (millimolar): 2.368496
 - cai in component intracellular_ions (millimolar): 0.000104
 - m in component INa (dimensionless): 0.004010
 - hf in component INa (dimensionless): 0.861204
 - hs in component INa (dimensionless): 0.861204
 - j in component INa (dimensionless): 0.861206
 - hsp in component INa (dimensionless): 0.691385
 - jp in component INa (dimensionless): 0.861208
 - mL in component INaL (dimensionless): 0.000060
 - hL in component INaL (dimensionless): 0.701551
 - hLp in component INaL (dimensionless): 0.506668
 - a in component Ito (dimensionless): 0.000668
 - iF in component Ito (dimensionless): 0.999844
 - iS in component Ito (dimensionless): 0.999844
 - ap in component Ito (dimensionless): 0.000340
 - iFp in component Ito (dimensionless): 0.999844
 - iSp in component Ito (dimensionless): 0.999844
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998800
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005127
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.001910
 - xs1 in component IKs (dimensionless): 0.023139
 - xs2 in component IKs (dimensionless): 0.000098
 - xk1 in component IK1 (dimensionless): 0.997592
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
06:55:23 (5044): called boinc_finish(0)

</stderr_txt>
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