𝕏

Task 54835106

Name HuVeMOp_20240626114313200281_ORdGradInc_k_24-Drouin_EPI_5000-conf_195_0
Workunit 26036795
Created 26 Jun 2024, 9:48:45 UTC
Sent 26 Jun 2024, 14:10:25 UTC
Report deadline 29 Jun 2024, 14:10:25 UTC
Received 1 Jul 2024, 7:26:23 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 236947
Run time 3 hours 17 min 42 sec
CPU time 2 hours 45 min 5 sec
Validate state Task was reported too late to validate
Credit 0.00
Device peak FLOPS 3.19 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.18 MB
Peak swap size 6.22 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626114313200281_ORdGradInc_k_24-Drouin_EPI_5000-conf_195.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626114313200281_ORdGradInc_k_24-Drouin_EPI_5000-conf_195_0_r1649241721_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626114313200281_ORdGradInc_k_24-Drouin_EPI_5000-conf_195_0_r1649241721_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 100.635388
     * GNaL_b in INaL: 0.007897
     * Gto_b in Ito: 0.069835
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.034026
     * GKs_b in IKs: 0.001754
     * GK1_b in IK1: 0.166920
     * Gncx_b in INaCa_i: 0.000946
     * Pnak_b in INaK: 66.584375
     * GKb_b in IKb: 0.003895
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.054823
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 600.000000
     * CL_0 in membrane: 5000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 8617279, states[0] = -94.366581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 17007561, states[0] = -94.299254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25385177, states[0] = -94.226067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33281864, states[0] = -94.286277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 41699502, states[0] = -94.254428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 50226859, states[0] = -93.773388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 57972737, states[0] = -94.258195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 66727097, states[0] = -94.254375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 75336262, states[0] = -94.148022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 83876835, states[0] = -94.266042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 92117814, states[0] = -94.255077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 100591411, states[0] = -94.289676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 109172633, states[0] = -94.264694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 117601867, states[0] = 1.552514, states[40]= 0.000080
Saving checkpoint... 
Iteration: 125932090, states[0] = -94.288458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 134692466, states[0] = -94.260564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 143167459, states[0] = -94.297448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 151572754, states[0] = -94.270854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 159789551, states[0] = -94.261168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 168647882, states[0] = -94.283002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 177177254, states[0] = -94.262831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 185800180, states[0] = -94.296605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 194077202, states[0] = -94.272010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 202903322, states[0] = -94.237970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 211401326, states[0] = -94.276165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 219929424, states[0] = -94.260994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 228399216, states[0] = -94.293173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 237099070, states[0] = -94.264152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 245534023, states[0] = -94.290142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 254087091, states[0] = -94.271931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 262434920, states[0] = -94.260864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 271028884, states[0] = -94.287898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 279275479, states[0] = -94.268378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 287800415, states[0] = -94.087006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 296415832, states[0] = -94.275537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 304718993, states[0] = -94.262525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 313634484, states[0] = -94.283748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 321755333, states[0] = -94.268413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 329827184, states[0] = -94.261318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 338320951, states[0] = -94.295562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346986785, states[0] = -94.264832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 355372423, states[0] = -94.208923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 363733078, states[0] = -94.280116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 372182471, states[0] = -94.262372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 380166495, states[0] = -71.100606, states[40]= 0.000003
Saving checkpoint... 
Iteration: 389042835, states[0] = -94.271889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 397136230, states[0] = -94.262660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 405483365, states[0] = -94.277323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 413701926, states[0] = -94.280695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 422094951, states[0] = -94.262916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 430423346, states[0] = -94.250452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 438770146, states[0] = -94.278378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 447274550, states[0] = -94.260848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 455554929, states[0] = -94.291623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 464052895, states[0] = -94.271060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 472406274, states[0] = -94.259485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 481287865, states[0] = -94.277507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 489727289, states[0] = -94.260953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 498080085, states[0] = -94.293902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 506418650, states[0] = -94.273784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 514565614, states[0] = -94.262492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 522916173, states[0] = -94.245113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 531748270, states[0] = -94.266822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 540208398, states[0] = -93.666532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 548492043, states[0] = -94.287141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 557333617, states[0] = -94.259401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 566198276, states[0] = -94.279557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 574656793, states[0] = -94.260975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 582917509, states[0] = -94.245498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 591200443, states[0] = -94.279280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599483867, states[0] = -94.262796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 607983359, states[0] = -94.275654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 616561508, states[0] = -94.269620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 624938950, states[0] = -94.257961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 633529322, states[0] = -94.284991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 642034082, states[0] = -94.261816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 650474236, states[0] = -94.272334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 658916516, states[0] = -94.272578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 667512648, states[0] = 23.805278, states[40]= 0.000008
Saving checkpoint... 
Iteration: 676386583, states[0] = -94.273192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685108834, states[0] = -4.148479, states[40]= 0.000132
Saving checkpoint... 
Iteration: 693828860, states[0] = -94.274590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 702135164, states[0] = -94.260154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 710315791, states[0] = -94.118994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 718958553, states[0] = -94.271063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 727330084, states[0] = -94.258027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 735863233, states[0] = -94.290716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 744373222, states[0] = -94.263112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 752840405, states[0] = -94.163524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 761055038, states[0] = -94.282962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 768930617, states[0] = -94.271321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 777831898, states[0] = -94.149245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 786276298, states[0] = -94.275329, states[40]= 0.000000
Saving checkpoint... 
Iteration: 795214558, states[0] = -93.706615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 803954226, states[0] = -94.270463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 812390803, states[0] = -94.256802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 821114135, states[0] = -94.280307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 829655735, states[0] = -94.258878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 837921159, states[0] = -94.245732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 846059570, states[0] = -94.282091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 854533972, states[0] = -94.260061, states[40]= 0.000000
Saving checkpoint... 
Iteration: 862875577, states[0] = -94.208105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 871162975, states[0] = -94.278205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 879541985, states[0] = -94.259757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 887934068, states[0] = -94.252865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 896263242, states[0] = -94.274809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 904596351, states[0] = -94.258913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 912646016, states[0] = -45.111084, states[40]= 0.000086
Saving checkpoint... 
Iteration: 921438591, states[0] = -94.269868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 930132588, states[0] = -29.411310, states[40]= 0.000216
Saving checkpoint... 
Iteration: 938484353, states[0] = -94.284227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 946521705, states[0] = -94.267746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 954972481, states[0] = -94.254971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 963548638, states[0] = -94.281533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 972048822, states[0] = -94.258910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 980048187, states[0] = 25.763977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 988449971, states[0] = -94.285183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 996678507, states[0] = -94.264199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1004917742, states[0] = -94.254989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1013380947, states[0] = -94.287735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1021802204, states[0] = -94.261895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1030253805, states[0] = -93.922857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1038842430, states[0] = -94.271369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1047447898, states[0] = -94.254397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1055533249, states[0] = -94.283533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1064194779, states[0] = -94.263348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1072692250, states[0] = -93.509078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1080966791, states[0] = -94.283749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1089274977, states[0] = -94.261774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1097868476, states[0] = -94.198389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1106031447, states[0] = -94.281012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1114049998, states[0] = -94.265753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1122627054, states[0] = -23.286280, states[40]= 0.000170
Saving checkpoint... 
Iteration: 1130868961, states[0] = -94.287237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1139631428, states[0] = -94.256579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1149063980, states[0] = -94.265170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1157603398, states[0] = 0.205079, states[40]= 0.000093
Saving checkpoint... 
Iteration: 1165896036, states[0] = -94.285879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1174212587, states[0] = -94.262124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1182509632, states[0] = 21.982443, states[40]= 0.000050
Saving checkpoint... 
Iteration: 1191620581, states[0] = -94.263679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1199570052, states[0] = -94.256778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1207958531, states[0] = -94.261826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1216361824, states[0] = -94.269381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1224892968, states[0] = -94.253373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1233566102, states[0] = -94.278651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1241976990, states[0] = -94.257574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1250373395, states[0] = -94.202576, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1258910507, states[0] = -94.267773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1267294687, states[0] = -94.253882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1275255019, states[0] = -93.926134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1283740281, states[0] = -94.272308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1292096292, states[0] = -94.255710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1300886708, states[0] = -94.285137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1309116123, states[0] = -94.262795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1317470817, states[0] = -94.251986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1325820678, states[0] = -94.287449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1334015002, states[0] = -94.264693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1342400124, states[0] = -94.252342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1351014042, states[0] = -94.279662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1359557638, states[0] = -94.255602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1368132417, states[0] = -94.289646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1376512530, states[0] = -94.264396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1385179641, states[0] = -90.958638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1393907639, states[0] = -94.266730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1402211041, states[0] = -94.253572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1410579465, states[0] = -94.286331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1419119255, states[0] = -94.261825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1427926532, states[0] = -94.244135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1436414867, states[0] = -94.266198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1445263794, states[0] = -93.961100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1453734585, states[0] = -94.271081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1462412008, states[0] = -94.251253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1470487437, states[0] = -94.269771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1478294982, states[0] = -94.287081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1486198935, states[0] = -94.271942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1494621264, states[0] = -94.253756, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.126232
 - CaMKt in component CaMK (millimolar): 0.001667
 - cass in component intracellular_ions (millimolar): 0.000100
 - nai in component intracellular_ions (millimolar): 7.184214
 - nass in component intracellular_ions (millimolar): 7.184344
 - ki in component intracellular_ions (millimolar): 144.530963
 - kss in component intracellular_ions (millimolar): 144.530950
 - cansr in component intracellular_ions (millimolar): 2.361478
 - cajsr in component intracellular_ions (millimolar): 2.361678
 - cai in component intracellular_ions (millimolar): 0.000104
 - m in component INa (dimensionless): 0.003913
 - hf in component INa (dimensionless): 0.865876
 - hs in component INa (dimensionless): 0.865876
 - j in component INa (dimensionless): 0.865878
 - hsp in component INa (dimensionless): 0.699781
 - jp in component INa (dimensionless): 0.865879
 - mL in component INaL (dimensionless): 0.000057
 - hL in component INaL (dimensionless): 0.708249
 - hLp in component INaL (dimensionless): 0.514699
 - a in component Ito (dimensionless): 0.000657
 - iF in component Ito (dimensionless): 0.999851
 - iS in component Ito (dimensionless): 0.999851
 - ap in component Ito (dimensionless): 0.000335
 - iFp in component Ito (dimensionless): 0.999851
 - iSp in component Ito (dimensionless): 0.999851
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998821
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005080
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.001766
 - xs1 in component IKs (dimensionless): 0.022829
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997534
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
12:04:15 (9976): called boinc_finish(0)

</stderr_txt>
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