𝕏

Task 54834876

Name HuVeMOp_20240626114313200281_ORdGradInc_k_24-Schmidt_500-conf_592_0
Workunit 26036680
Created 26 Jun 2024, 9:48:40 UTC
Sent 26 Jun 2024, 14:10:38 UTC
Report deadline 29 Jun 2024, 14:10:38 UTC
Received 1 Jul 2024, 7:27:09 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 236947
Run time 3 hours 21 min 11 sec
CPU time 2 hours 47 min 47 sec
Validate state Task was reported too late to validate
Credit 0.00
Device peak FLOPS 3.19 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.18 MB
Peak swap size 6.22 MB
Peak disk usage 0.18 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626114313200281_ORdGradInc_k_24-Schmidt_500-conf_592.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626114313200281_ORdGradInc_k_24-Schmidt_500-conf_592_0_r1145625652_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626114313200281_ORdGradInc_k_24-Schmidt_500-conf_592_0_r1145625652_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 109.613984
     * GNaL_b in INaL: 0.006524
     * Gto_b in Ito: 0.072136
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033019
     * GKs_b in IKs: 0.001774
     * GK1_b in IK1: 0.153964
     * Gncx_b in INaCa_i: 0.000957
     * Pnak_b in INaK: 62.641074
     * GKb_b in IKb: 0.003862
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037227
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 6000.000000
     * CL_0 in membrane: 500.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499750000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 8319080, states[0] = 5.629827, states[40]= 0.002191
Saving checkpoint... 
Iteration: 16265900, states[0] = 32.057345, states[40]= 0.007357
Saving checkpoint... 
Iteration: 24075683, states[0] = 0.144199, states[40]= 0.000393
Saving checkpoint... 
Iteration: 32036973, states[0] = 24.087313, states[40]= 0.000009
Saving checkpoint... 
Iteration: 40297104, states[0] = 18.625594, states[40]= 0.000013
Saving checkpoint... 
Iteration: 48387571, states[0] = -75.844258, states[40]= 0.000001
Saving checkpoint... 
Iteration: 56912886, states[0] = -84.309581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 65586927, states[0] = -13.854084, states[40]= 0.000221
Saving checkpoint... 
Iteration: 74066642, states[0] = 6.018899, states[40]= 0.000102
Saving checkpoint... 
Iteration: 82376347, states[0] = -62.409297, states[40]= 0.000008
Saving checkpoint... 
Iteration: 91075578, states[0] = -1.388661, states[40]= 0.000207
Saving checkpoint... 
Iteration: 98880306, states[0] = -67.948390, states[40]= 0.000004
Saving checkpoint... 
Iteration: 106851226, states[0] = -32.405233, states[40]= 0.000152
Saving checkpoint... 
Iteration: 114933273, states[0] = -84.562623, states[40]= 0.000001
Saving checkpoint... 
Iteration: 123396015, states[0] = -83.075100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 131850676, states[0] = -31.875083, states[40]= 0.000153
Saving checkpoint... 
Iteration: 140059049, states[0] = 10.988692, states[40]= 0.000042
Saving checkpoint... 
Iteration: 148785752, states[0] = 24.242992, states[40]= 0.000008
Saving checkpoint... 
Iteration: 156891161, states[0] = -80.875512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 165464026, states[0] = -84.789333, states[40]= 0.000001
Saving checkpoint... 
Iteration: 173762525, states[0] = 31.690835, states[40]= 0.026948
Saving checkpoint... 
Iteration: 181900025, states[0] = -83.820510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 190219236, states[0] = -84.818035, states[40]= 0.000001
Saving checkpoint... 
Iteration: 198224795, states[0] = -84.846466, states[40]= 0.000001
Saving checkpoint... 
Iteration: 206391244, states[0] = -80.954542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 214798429, states[0] = 17.417303, states[40]= 0.000011
Saving checkpoint... 
Iteration: 223408318, states[0] = -84.258473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 231453479, states[0] = -84.721781, states[40]= 0.000001
Saving checkpoint... 
Iteration: 239671282, states[0] = -84.445649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 248038310, states[0] = 22.928684, states[40]= 0.000005
Saving checkpoint... 
Iteration: 256115117, states[0] = -49.203880, states[40]= 0.000039
Saving checkpoint... 
Iteration: 264226327, states[0] = -84.851832, states[40]= 0.000001
Saving checkpoint... 
Iteration: 273008829, states[0] = 31.024339, states[40]= 0.103083
Saving checkpoint... 
Iteration: 281188703, states[0] = -84.608847, states[40]= 0.000001
Saving checkpoint... 
Iteration: 289572097, states[0] = 1.484975, states[40]= 0.000155
Saving checkpoint... 
Iteration: 298056460, states[0] = 12.614514, states[40]= 0.000030
Saving checkpoint... 
Iteration: 306628596, states[0] = -66.040393, states[40]= 0.000005
Saving checkpoint... 
Iteration: 315040448, states[0] = 21.810433, states[40]= 0.000005
Saving checkpoint... 
Iteration: 323261542, states[0] = 31.578390, states[40]= 0.038520
Saving checkpoint... 
Iteration: 331853985, states[0] = -35.948760, states[40]= 0.000124
Saving checkpoint... 
Iteration: 340054834, states[0] = 13.622853, states[40]= 0.000025
Saving checkpoint... 
Iteration: 348214738, states[0] = -84.787716, states[40]= 0.000001
Saving checkpoint... 
Iteration: 356353996, states[0] = -35.960710, states[40]= 0.000124
Saving checkpoint... 
Iteration: 364998398, states[0] = -84.939234, states[40]= 0.000001
Saving checkpoint... 
Iteration: 373499589, states[0] = -84.943051, states[40]= 0.000001
Saving checkpoint... 
Iteration: 381750204, states[0] = -59.805758, states[40]= 0.000001
Saving checkpoint... 
Iteration: 390360849, states[0] = -44.110726, states[40]= 0.000065
Saving checkpoint... 
Iteration: 399066493, states[0] = 5.864790, states[40]= 0.000093
Saving checkpoint... 
Iteration: 407369417, states[0] = -54.377548, states[40]= 0.000022
Saving checkpoint... 
Iteration: 415312588, states[0] = 8.619861, states[40]= 0.000062
Saving checkpoint... 
Iteration: 423667281, states[0] = -84.393341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 431847056, states[0] = -27.551515, states[40]= 0.000161
Saving checkpoint... 
Iteration: 440427712, states[0] = -84.503915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 448718339, states[0] = -84.804108, states[40]= 0.000001
Saving checkpoint... 
Iteration: 456967585, states[0] = -84.799681, states[40]= 0.000001
Saving checkpoint... 
Iteration: 465229983, states[0] = -84.861670, states[40]= 0.000001
Saving checkpoint... 
Iteration: 474239734, states[0] = -84.902941, states[40]= 0.000001
Saving checkpoint... 
Iteration: 482746106, states[0] = -84.926773, states[40]= 0.000001
Saving checkpoint... 
Iteration: 490686724, states[0] = -84.584304, states[40]= 0.000001
Saving checkpoint... 
Iteration: 499127161, states[0] = -64.118445, states[40]= 0.000006
Saving checkpoint... 
Iteration: 507207845, states[0] = -84.740253, states[40]= 0.000001
Saving checkpoint... 
Iteration: 515562925, states[0] = 8.391376, states[40]= 0.000064
Saving checkpoint... 
Iteration: 523928687, states[0] = -84.510186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 532131843, states[0] = -70.419842, states[40]= 0.000003
Saving checkpoint... 
Iteration: 540611922, states[0] = -45.378075, states[40]= 0.000057
Saving checkpoint... 
Iteration: 549535905, states[0] = 24.160072, states[40]= 0.000008
Saving checkpoint... 
Iteration: 558071636, states[0] = 1.876767, states[40]= 0.000149
Saving checkpoint... 
Iteration: 566802520, states[0] = 15.028392, states[40]= 0.000019
Saving checkpoint... 
Iteration: 574774885, states[0] = 29.185617, states[40]= 0.000314
Saving checkpoint... 
Iteration: 583558356, states[0] = 11.418558, states[40]= 0.000038
Saving checkpoint... 
Iteration: 592079885, states[0] = -6.051789, states[40]= 0.000230
Saving checkpoint... 
Iteration: 600357294, states[0] = -39.876799, states[40]= 0.000094
Saving checkpoint... 
Iteration: 609023618, states[0] = 29.664403, states[40]= 0.000494
Saving checkpoint... 
Iteration: 617448258, states[0] = -84.670901, states[40]= 0.000001
Saving checkpoint... 
Iteration: 626034749, states[0] = 24.738490, states[40]= 0.000011
Saving checkpoint... 
Iteration: 634559479, states[0] = 10.694122, states[40]= 0.000043
Saving checkpoint... 
Iteration: 642967033, states[0] = -84.789762, states[40]= 0.000001
Saving checkpoint... 
Iteration: 651535665, states[0] = 24.282123, states[40]= 0.000009
Saving checkpoint... 
Iteration: 660178070, states[0] = -84.499126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 668818416, states[0] = 4.435537, states[40]= 0.000112
Saving checkpoint... 
Iteration: 676796412, states[0] = 18.565624, states[40]= 0.000008
Saving checkpoint... 
Iteration: 685265254, states[0] = 31.698919, states[40]= 0.010005
Saving checkpoint... 
Iteration: 693755657, states[0] = 30.870549, states[40]= 0.320393
Saving checkpoint... 
Iteration: 702405955, states[0] = -84.173244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 710573728, states[0] = 0.089153, states[40]= 0.000175
Saving checkpoint... 
Iteration: 719152927, states[0] = -84.036122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 727557941, states[0] = 11.686353, states[40]= 0.000036
Saving checkpoint... 
Iteration: 736151275, states[0] = -83.917874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 744565492, states[0] = 6.596979, states[40]= 0.000084
Saving checkpoint... 
Iteration: 752915054, states[0] = -84.352850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 761383150, states[0] = -72.165307, states[40]= 0.000002
Saving checkpoint... 
Iteration: 769628792, states[0] = -66.260037, states[40]= 0.000005
Saving checkpoint... 
Iteration: 777769303, states[0] = 31.016159, states[40]= 0.002319
Saving checkpoint... 
Iteration: 786028978, states[0] = 27.470259, states[40]= 0.000074
Saving checkpoint... 
Iteration: 794674971, states[0] = -84.463390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 802599970, states[0] = -31.091117, states[40]= 0.000154
Saving checkpoint... 
Iteration: 811119874, states[0] = -54.906684, states[40]= 0.000020
Saving checkpoint... 
Iteration: 819337486, states[0] = -15.416979, states[40]= 0.000181
Saving checkpoint... 
Iteration: 827655669, states[0] = -84.158266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 836388940, states[0] = -79.036025, states[40]= 0.000001
Saving checkpoint... 
Iteration: 844659010, states[0] = -84.249921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 853176957, states[0] = -84.481015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861348962, states[0] = -29.862555, states[40]= 0.000158
Saving checkpoint... 
Iteration: 869892628, states[0] = -81.743100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 878501259, states[0] = 37.461578, states[40]= 0.892524
Saving checkpoint... 
Iteration: 887021080, states[0] = 30.522722, states[40]= 0.001225
Saving checkpoint... 
Iteration: 895523378, states[0] = 29.755556, states[40]= 0.000538
Saving checkpoint... 
Iteration: 903814687, states[0] = 7.173150, states[40]= 0.000077
Saving checkpoint... 
Iteration: 912248407, states[0] = -84.919224, states[40]= 0.000001
Saving checkpoint... 
Iteration: 920623567, states[0] = -59.464391, states[40]= 0.000012
Saving checkpoint... 
Iteration: 929161561, states[0] = -84.294815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 937358934, states[0] = -41.806023, states[40]= 0.000080
Saving checkpoint... 
Iteration: 945755197, states[0] = 31.131709, states[40]= 0.376583
Saving checkpoint... 
Iteration: 953724986, states[0] = -84.819921, states[40]= 0.000001
Saving checkpoint... 
Iteration: 962327753, states[0] = -3.745430, states[40]= 0.000218
Saving checkpoint... 
Iteration: 970817390, states[0] = 5.215291, states[40]= 0.000101
Saving checkpoint... 
Iteration: 978966910, states[0] = -84.776664, states[40]= 0.000001
Saving checkpoint... 
Iteration: 987553287, states[0] = 14.574578, states[40]= 0.000021
Saving checkpoint... 
Iteration: 995781980, states[0] = 26.088600, states[40]= 0.000026
Saving checkpoint... 
Iteration: 1003893427, states[0] = -82.131300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1012226976, states[0] = -84.827444, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1020295474, states[0] = 19.094528, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1028786178, states[0] = 24.029478, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1037327105, states[0] = -3.083415, states[40]= 0.000213
Saving checkpoint... 
Iteration: 1045410915, states[0] = -84.279267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1053429132, states[0] = -84.494548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1061445007, states[0] = -84.630093, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1069541007, states[0] = 21.524843, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1077583806, states[0] = -10.699280, states[40]= 0.000217
Saving checkpoint... 
Iteration: 1085547646, states[0] = 17.875338, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1094090064, states[0] = -18.731395, states[40]= 0.000163
Saving checkpoint... 
Iteration: 1102495430, states[0] = -84.901603, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1110973766, states[0] = -84.808048, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1118958571, states[0] = -84.722160, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1126834412, states[0] = -11.458517, states[40]= 0.000212
Saving checkpoint... 
Iteration: 1135069622, states[0] = 3.514325, states[40]= 0.000125
Saving checkpoint... 
Iteration: 1143177407, states[0] = -84.474521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1151337048, states[0] = -14.833974, states[40]= 0.000186
Saving checkpoint... 
Iteration: 1159508639, states[0] = 30.985456, states[40]= 0.110301
Saving checkpoint... 
Iteration: 1167473812, states[0] = -84.806196, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1175651275, states[0] = -83.897930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1183982823, states[0] = -84.847980, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1192247325, states[0] = -84.905149, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1200310138, states[0] = 10.273467, states[40]= 0.000047
Saving checkpoint... 
Iteration: 1208458671, states[0] = -84.719471, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1216421046, states[0] = -84.406292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1224988101, states[0] = -84.868817, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1233232963, states[0] = -84.846784, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1241283803, states[0] = 25.213214, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1249507723, states[0] = 30.788302, states[40]= 0.153403
Saving checkpoint... 
Iteration: 1257744106, states[0] = -84.891022, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1266109396, states[0] = -42.336328, states[40]= 0.000076
Saving checkpoint... 
Iteration: 1274534996, states[0] = 24.625327, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1282684392, states[0] = -84.534317, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1291065158, states[0] = 6.847014, states[40]= 0.000081
Saving checkpoint... 
Iteration: 1299355504, states[0] = -37.710468, states[40]= 0.000111
Saving checkpoint... 
Iteration: 1307167575, states[0] = -84.363359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1315811421, states[0] = 9.425147, states[40]= 0.000054
Saving checkpoint... 
Iteration: 1324188866, states[0] = -84.571241, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1332384695, states[0] = -74.142401, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1340768168, states[0] = 31.284592, states[40]= 0.003488
Saving checkpoint... 
Iteration: 1349000667, states[0] = 32.546401, states[40]= 0.136761
Saving checkpoint... 
Iteration: 1357112419, states[0] = -45.922360, states[40]= 0.000054
Saving checkpoint... 
Iteration: 1365675866, states[0] = -84.450907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1373839729, states[0] = -18.286204, states[40]= 0.000164
Saving checkpoint... 
Iteration: 1382139707, states[0] = -79.670976, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1389924625, states[0] = -84.437450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1398147768, states[0] = -83.435858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406138641, states[0] = -78.690228, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1414365280, states[0] = -49.330300, states[40]= 0.000038
Saving checkpoint... 
Iteration: 1422179657, states[0] = -84.485685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1430762267, states[0] = 31.677479, states[40]= 0.029561
Saving checkpoint... 
Iteration: 1439000849, states[0] = 34.918737, states[40]= 0.369000
Saving checkpoint... 
Iteration: 1446928516, states[0] = -84.473860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1454887083, states[0] = -77.040067, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1463378152, states[0] = -65.341883, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1471837579, states[0] = -15.504309, states[40]= 0.000181
Saving checkpoint... 
Iteration: 1479931794, states[0] = -84.503461, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1488223667, states[0] = -84.793639, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1496553643, states[0] = 14.367698, states[40]= 0.000021
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -84.778968
 - CaMKt in component CaMK (millimolar): 0.083875
 - cass in component intracellular_ions (millimolar): 0.000122
 - nai in component intracellular_ions (millimolar): 7.205379
 - nass in component intracellular_ions (millimolar): 7.205584
 - ki in component intracellular_ions (millimolar): 144.260262
 - kss in component intracellular_ions (millimolar): 144.260229
 - cansr in component intracellular_ions (millimolar): 2.504684
 - cajsr in component intracellular_ions (millimolar): 1.936867
 - cai in component intracellular_ions (millimolar): 0.000120
 - m in component INa (dimensionless): 0.010025
 - hf in component INa (dimensionless): 0.581545
 - hs in component INa (dimensionless): 0.581176
 - j in component INa (dimensionless): 0.578873
 - hsp in component INa (dimensionless): 0.333005
 - jp in component INa (dimensionless): 0.575150
 - mL in component INaL (dimensionless): 0.000339
 - hL in component INaL (dimensionless): 0.296790
 - hLp in component INaL (dimensionless): 0.124878
 - a in component Ito (dimensionless): 0.001234
 - iF in component Ito (dimensionless): 0.999232
 - iS in component Ito (dimensionless): 0.256557
 - ap in component Ito (dimensionless): 0.000629
 - iFp in component Ito (dimensionless): 0.999232
 - iSp in component Ito (dimensionless): 0.284158
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.785123
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.982044
 - jca in component ICaL (dimensionless): 0.986807
 - ffp in component ICaL (dimensionless): 0.999999
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.010873
 - xrf in component IKr (dimensionless): 0.006499
 - xrs in component IKr (dimensionless): 0.770566
 - xs1 in component IKs (dimensionless): 0.459557
 - xs2 in component IKs (dimensionless): 0.000341
 - xk1 in component IK1 (dimensionless): 0.996736
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
13:35:47 (6364): called boinc_finish(0)

</stderr_txt>
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