𝕏

Task 54834656

Name HuVeMOp_20240626114313200281_ORdGradInc_k_24-Drouin_ENDO_4000-conf_891_0
Workunit 26036570
Created 26 Jun 2024, 9:48:35 UTC
Sent 26 Jun 2024, 14:10:25 UTC
Report deadline 29 Jun 2024, 14:10:25 UTC
Received 1 Jul 2024, 7:26:23 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 236947
Run time 3 hours 15 min 56 sec
CPU time 2 hours 43 min 58 sec
Validate state Task was reported too late to validate
Credit 0.00
Device peak FLOPS 3.19 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.17 MB
Peak swap size 6.22 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626114313200281_ORdGradInc_k_24-Drouin_ENDO_4000-conf_891.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626114313200281_ORdGradInc_k_24-Drouin_ENDO_4000-conf_891_0_r68243206_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626114313200281_ORdGradInc_k_24-Drouin_ENDO_4000-conf_891_0_r68243206_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 102.255788
     * GNaL_b in INaL: 0.007142
     * Gto_b in Ito: 0.069527
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.032119
     * GKs_b in IKs: 0.001840
     * GK1_b in IK1: 0.175099
     * Gncx_b in INaCa_i: 0.000971
     * Pnak_b in INaK: 66.018177
     * GKb_b in IKb: 0.004035
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.044360
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 8601495, states[0] = -94.366661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 17043679, states[0] = -94.309603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25730010, states[0] = -94.259895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 34103033, states[0] = 3.345127, states[40]= 0.004092
Saving checkpoint... 
Iteration: 42835481, states[0] = -94.258310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 51299654, states[0] = -94.240416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59658966, states[0] = -94.229676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 68542369, states[0] = -94.230624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 77141191, states[0] = -94.242108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 85788544, states[0] = -94.225479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 94435626, states[0] = -94.179412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 102919543, states[0] = -94.249027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 111471675, states[0] = -94.231884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 120096663, states[0] = 6.640868, states[40]= 0.003534
Saving checkpoint... 
Iteration: 128747302, states[0] = -94.251302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 137503571, states[0] = -94.231006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 145897522, states[0] = -94.223272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 154430660, states[0] = -94.175315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 163059390, states[0] = -94.244236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 171494486, states[0] = -94.231134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 180153385, states[0] = -32.399938, states[40]= 0.002216
Saving checkpoint... 
Iteration: 188706462, states[0] = -94.250211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 196934173, states[0] = -94.248294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 205855644, states[0] = -94.223796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 214323930, states[0] = -94.028074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 222436721, states[0] = -94.179786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 230930165, states[0] = -94.248335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 239537005, states[0] = -94.229964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 248215462, states[0] = -91.766073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 256486833, states[0] = -94.209369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 265026979, states[0] = -94.245105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 273042343, states[0] = -94.244562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 281616265, states[0] = -94.228108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 290333747, states[0] = -94.048750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 298240581, states[0] = -93.743601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 306761858, states[0] = -94.250995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 315233313, states[0] = -94.238085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 323622407, states[0] = -94.227882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 332003865, states[0] = 37.223802, states[40]= 0.477564
Saving checkpoint... 
Iteration: 340394195, states[0] = -94.140554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 349171228, states[0] = -94.240014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 357452788, states[0] = -94.231740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 366040614, states[0] = 28.158758, states[40]= 0.000268
Saving checkpoint... 
Iteration: 374572951, states[0] = -94.236168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 383532774, states[0] = -94.229735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 391755450, states[0] = -94.225110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 400168716, states[0] = -44.003132, states[40]= 0.000611
Saving checkpoint... 
Iteration: 408586065, states[0] = -94.238532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 416775186, states[0] = -94.250784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 425627527, states[0] = -94.227543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 434240546, states[0] = -93.743114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 442777193, states[0] = -94.250725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 451516587, states[0] = -94.229961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 460375495, states[0] = -94.117416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 469064003, states[0] = -94.243374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 477333237, states[0] = -94.234703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 485943480, states[0] = -94.221776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 494290621, states[0] = -93.939167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 502560081, states[0] = -94.233140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 511410864, states[0] = -94.232480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 519635075, states[0] = -94.227172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 528505092, states[0] = -94.216506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 537059309, states[0] = -94.243382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 545593833, states[0] = -94.227992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 554249042, states[0] = -93.781892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 562961150, states[0] = -94.246619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 571693296, states[0] = -94.225879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 580405082, states[0] = -94.151537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 589043310, states[0] = -94.243813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 597720367, states[0] = -94.225298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 605771224, states[0] = -94.224339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 614655399, states[0] = -94.246449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 623236515, states[0] = -94.237287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 631789319, states[0] = -94.223958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 639934464, states[0] = -94.221563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 648670155, states[0] = -94.247408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 657192334, states[0] = -94.238624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 665142937, states[0] = -94.240241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 673724774, states[0] = -94.225042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 682598884, states[0] = -94.239993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 691297299, states[0] = -94.235271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 700279554, states[0] = -93.902307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 708802658, states[0] = -94.250003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 717686910, states[0] = -94.225673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 726257169, states[0] = -93.816492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 734714222, states[0] = -94.249222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742740806, states[0] = -94.249795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 751086010, states[0] = -94.241981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 759534743, states[0] = -94.228837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 767816691, states[0] = -94.223173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 776212876, states[0] = -90.004294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 784777941, states[0] = -94.249952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 793115383, states[0] = -94.240883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 801511162, states[0] = -94.229297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 809837747, states[0] = -94.222721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 818334486, states[0] = -94.049030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 827417852, states[0] = -94.231579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 835994854, states[0] = -94.220230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 844010283, states[0] = 32.521306, states[40]= 0.052359
Saving checkpoint... 
Iteration: 852577613, states[0] = -94.235993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 860865392, states[0] = -94.248637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 869548401, states[0] = -94.228273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 877978411, states[0] = -94.220372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 886489416, states[0] = -94.209121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 894518578, states[0] = -94.220597, states[40]= 0.000000
Saving checkpoint... 
Iteration: 902703598, states[0] = -94.248488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 911245020, states[0] = -94.236368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 919721768, states[0] = -94.224541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 928289728, states[0] = -93.935374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 936815931, states[0] = -94.249347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 945330582, states[0] = -94.233720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 953744321, states[0] = -94.224042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 962507879, states[0] = -94.216593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 970639920, states[0] = -94.244317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 979233941, states[0] = -94.236562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 987558958, states[0] = -94.227765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 996144346, states[0] = -25.889738, states[40]= 0.002811
Saving checkpoint... 
Iteration: 1004784240, states[0] = -94.249442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1012522870, states[0] = -94.221766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1021047356, states[0] = -94.242697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1029442658, states[0] = -94.230476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1038087602, states[0] = 10.782471, states[40]= 0.002721
Saving checkpoint... 
Iteration: 1047202263, states[0] = -94.237419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1056023663, states[0] = 32.358335, states[40]= 0.000610
Saving checkpoint... 
Iteration: 1064607939, states[0] = -94.240435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1073013136, states[0] = -94.243746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1081521522, states[0] = -94.228417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1090242284, states[0] = -93.749907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1098841451, states[0] = -94.248588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1107179557, states[0] = -94.238023, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1115454677, states[0] = -94.229975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1124026443, states[0] = 31.860803, states[40]= 0.000315
Saving checkpoint... 
Iteration: 1132808747, states[0] = -94.248986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1141030571, states[0] = -94.243000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1149461768, states[0] = -94.229719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1158119239, states[0] = -6.683135, states[40]= 0.003402
Saving checkpoint... 
Iteration: 1166795918, states[0] = -94.249019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1174887528, states[0] = -94.247392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1183325188, states[0] = -94.233337, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1191699993, states[0] = -94.224343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1200264477, states[0] = -93.845176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1208727929, states[0] = -94.248505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1217233084, states[0] = -94.236050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1225568009, states[0] = -94.227022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1234054590, states[0] = 23.527074, states[40]= 0.000586
Saving checkpoint... 
Iteration: 1242371983, states[0] = -94.110857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1250895960, states[0] = -94.247000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1259375526, states[0] = -94.231742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1268052842, states[0] = 24.135093, states[40]= 0.000531
Saving checkpoint... 
Iteration: 1276493877, states[0] = -94.210210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1285266377, states[0] = -94.234860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1293821812, states[0] = -94.221893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1302188881, states[0] = -60.957029, states[40]= 0.000047
Saving checkpoint... 
Iteration: 1310804495, states[0] = -94.248625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1319420799, states[0] = -94.230387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1328337319, states[0] = -94.053468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336911933, states[0] = -94.246365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1345615178, states[0] = -94.225720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1354127783, states[0] = -13.326543, states[40]= 0.002154
Saving checkpoint... 
Iteration: 1362873218, states[0] = -94.247321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1371331478, states[0] = -94.232729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1378995721, states[0] = -94.243640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1387011542, states[0] = -94.243090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1395445389, states[0] = -94.229577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1403784960, states[0] = -94.222285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1412743873, states[0] = -94.248325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1421555955, states[0] = -94.226850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1430371752, states[0] = -94.110109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1439306744, states[0] = -94.233297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1447957990, states[0] = -94.219379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1456815380, states[0] = -94.248178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1465366433, states[0] = -94.231527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1473838188, states[0] = -94.221208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1482387756, states[0] = -94.130545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1491151193, states[0] = -94.238095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1499516090, states[0] = -94.227599, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.094621
 - CaMKt in component CaMK (millimolar): 0.002086
 - cass in component intracellular_ions (millimolar): 0.000101
 - nai in component intracellular_ions (millimolar): 6.757650
 - nass in component intracellular_ions (millimolar): 6.757774
 - ki in component intracellular_ions (millimolar): 145.101040
 - kss in component intracellular_ions (millimolar): 145.101029
 - cansr in component intracellular_ions (millimolar): 1.835556
 - cajsr in component intracellular_ions (millimolar): 1.835313
 - cai in component intracellular_ions (millimolar): 0.000105
 - m in component INa (dimensionless): 0.003926
 - hf in component INa (dimensionless): 0.865272
 - hs in component INa (dimensionless): 0.865273
 - j in component INa (dimensionless): 0.865276
 - hsp in component INa (dimensionless): 0.698690
 - jp in component INa (dimensionless): 0.865278
 - mL in component INaL (dimensionless): 0.000058
 - hL in component INaL (dimensionless): 0.707397
 - hLp in component INaL (dimensionless): 0.513145
 - a in component Ito (dimensionless): 0.000658
 - iF in component Ito (dimensionless): 0.999850
 - iS in component Ito (dimensionless): 0.991558
 - ap in component Ito (dimensionless): 0.000335
 - iFp in component Ito (dimensionless): 0.999850
 - iSp in component Ito (dimensionless): 0.996663
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.996357
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005314
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.007768
 - xs1 in component IKs (dimensionless): 0.042021
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997541
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
12:16:35 (2624): called boinc_finish(0)

</stderr_txt>
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