𝕏

Task 54828187

Name HuVeMOp_20240626114313200281_ORdGradInc_k_24-Pueyo_APDR-conf_639_0
Workunit 26033338
Created 26 Jun 2024, 9:44:58 UTC
Sent 26 Jun 2024, 13:00:54 UTC
Report deadline 29 Jun 2024, 22:36:54 UTC
Received 28 Jun 2024, 1:58:00 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 232370
Run time 1 hours 37 min 37 sec
CPU time 1 hours 31 min 4 sec
Validate state Valid
Credit 56.88
Device peak FLOPS 3.99 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.15 MB
Peak swap size 6.22 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626114313200281_ORdGradInc_k_24-Pueyo_APDR-conf_639.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626114313200281_ORdGradInc_k_24-Pueyo_APDR-conf_639_0_r2020355962_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626114313200281_ORdGradInc_k_24-Pueyo_APDR-conf_639_0_r2020355962_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 124.240385
     * GNaL_b in INaL: 0.009337
     * Gto_b in Ito: 0.081329
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032004
     * GKs_b in IKs: 0.001839
     * GK1_b in IK1: 0.163423
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 62.665133
     * GKb_b in IKb: 0.003931
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.039402
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13648039, states[0] = -61.424824, states[40]= 0.000005
Saving checkpoint... 
Iteration: 28383465, states[0] = -94.966004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 43139481, states[0] = -50.612810, states[40]= 0.000030
Saving checkpoint... 
Iteration: 57362607, states[0] = -94.950996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 71842074, states[0] = -94.939900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 86337794, states[0] = -94.936664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 100797378, states[0] = -94.909384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 115436343, states[0] = -94.969701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 130192832, states[0] = -94.762096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 144689196, states[0] = -94.749182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 159067603, states[0] = 6.555563, states[40]= 0.004845
Saving checkpoint... 
Iteration: 173477333, states[0] = -94.976122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 183640847, states[0] = -51.612260, states[40]= 0.000025
Saving checkpoint... 
Iteration: 197551247, states[0] = 13.054418, states[40]= 0.005069
Saving checkpoint... 
Iteration: 211870490, states[0] = -94.949775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226194956, states[0] = -94.766904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 240593515, states[0] = -8.124447, states[40]= 0.002722
Saving checkpoint... 
Iteration: 255118630, states[0] = -29.766065, states[40]= 0.000546
Saving checkpoint... 
Iteration: 269169805, states[0] = -91.409286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 283773570, states[0] = -94.886451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 298015607, states[0] = 23.372653, states[40]= 0.017540
Saving checkpoint... 
Iteration: 312237549, states[0] = -94.842040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 326755058, states[0] = -94.865608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 340753338, states[0] = -94.863460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 355029851, states[0] = 20.247006, states[40]= 0.006301
Saving checkpoint... 
Iteration: 369325409, states[0] = -94.927564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 383711400, states[0] = -94.799011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 398062709, states[0] = 8.614817, states[40]= 0.004933
Saving checkpoint... 
Iteration: 411872249, states[0] = -94.950284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 425858806, states[0] = -94.944767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 440351765, states[0] = -94.941576, states[40]= 0.000000
Saving checkpoint... 
Iteration: 454595234, states[0] = -9.478801, states[40]= 0.002434
Saving checkpoint... 
Iteration: 468718543, states[0] = -94.811602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 483013330, states[0] = 23.759303, states[40]= 0.026488
Saving checkpoint... 
Iteration: 497399581, states[0] = -94.959469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 511784304, states[0] = -94.896690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 526474196, states[0] = -94.975304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 540382698, states[0] = -94.954023, states[40]= 0.000000
Saving checkpoint... 
Iteration: 554320817, states[0] = -94.924606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 568580579, states[0] = 0.315520, states[40]= 0.004307
Saving checkpoint... 
Iteration: 582866214, states[0] = -94.947794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 596765501, states[0] = -94.877661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 610764999, states[0] = -94.877094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 624645551, states[0] = -56.960925, states[40]= 0.000010
Saving checkpoint... 
Iteration: 639003878, states[0] = 34.354956, states[40]= 0.147890
Saving checkpoint... 
Iteration: 653416761, states[0] = -94.964068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 667435880, states[0] = -94.968463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 681462312, states[0] = -94.973371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 695508030, states[0] = 25.625039, states[40]= 0.085838
Saving checkpoint... 
Iteration: 705450606, states[0] = -94.971330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 719667958, states[0] = -89.459559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 733343455, states[0] = -94.937349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 747250419, states[0] = -94.859492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 761279414, states[0] = -94.891946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 775703471, states[0] = -94.784021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 790161118, states[0] = -78.328238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 804607354, states[0] = -19.874845, states[40]= 0.001024
Saving checkpoint... 
Iteration: 818687280, states[0] = -94.737616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 832640231, states[0] = -50.916306, states[40]= 0.000028
Saving checkpoint... 
Iteration: 842446414, states[0] = -94.970464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 856635846, states[0] = -46.152767, states[40]= 0.000060
Saving checkpoint... 
Iteration: 870701456, states[0] = -94.780073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 884756305, states[0] = -94.866792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 898468753, states[0] = -94.974261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 912590035, states[0] = -5.546771, states[40]= 0.003279
Saving checkpoint... 
Iteration: 926729781, states[0] = -94.829864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 940897082, states[0] = -94.958450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 955201549, states[0] = -94.780203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 969577984, states[0] = 1.690006, states[40]= 0.004470
Saving checkpoint... 
Iteration: 983935386, states[0] = -94.968166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 998066427, states[0] = 7.065726, states[40]= 0.004869
Saving checkpoint... 
Iteration: 1003246802, states[0] = -94.854578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1017204744, states[0] = -94.786294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1030733946, states[0] = -94.836229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1044737094, states[0] = -94.840919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1058959715, states[0] = -94.972710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1073078943, states[0] = 1.191347, states[40]= 0.004414
Saving checkpoint... 
Iteration: 1082777352, states[0] = -94.889744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1096608103, states[0] = -20.530693, states[40]= 0.000987
Saving checkpoint... 
Iteration: 1110695848, states[0] = -94.768371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1124880893, states[0] = -94.953033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1139099895, states[0] = -13.365568, states[40]= 0.001709
Saving checkpoint... 
Iteration: 1152943916, states[0] = -94.969793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1166883545, states[0] = -94.953933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1180761130, states[0] = -94.872345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1194940786, states[0] = -94.969149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1209290368, states[0] = -94.901645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1223459389, states[0] = -94.972555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1237289079, states[0] = -94.900511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1251490590, states[0] = -94.977077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1265638256, states[0] = -48.742145, states[40]= 0.000040
Saving checkpoint... 
Iteration: 1279729043, states[0] = -94.828482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1293888183, states[0] = -94.955419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1308206194, states[0] = -94.788845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1322030822, states[0] = 19.969977, states[40]= 0.006160
Saving checkpoint... 
Iteration: 1336312133, states[0] = -94.918380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1350322363, states[0] = -94.925090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1364114929, states[0] = -26.502096, states[40]= 0.000718
Saving checkpoint... 
Iteration: 1378118516, states[0] = -29.663718, states[40]= 0.000552
Saving checkpoint... 
Iteration: 1392316761, states[0] = -94.921470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406605000, states[0] = -17.810800, states[40]= 0.001170
Saving checkpoint... 
Iteration: 1420590151, states[0] = -5.628658, states[40]= 0.003262
Saving checkpoint... 
Iteration: 1435039592, states[0] = 17.203202, states[40]= 0.005399
Saving checkpoint... 
Iteration: 1449070211, states[0] = 5.412654, states[40]= 0.004780
Saving checkpoint... 
Iteration: 1462847280, states[0] = -94.938806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1477291653, states[0] = -94.902579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1491623944, states[0] = -34.532972, states[40]= 0.000315
Saving checkpoint... 
Iteration: 1505597480, states[0] = -95.088643, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1519599360, states[0] = -28.526640, states[40]= 0.000585
Saving checkpoint... 
Iteration: 1533317767, states[0] = 22.930636, states[40]= 0.014567
Saving checkpoint... 
Iteration: 1547244554, states[0] = -89.895811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1561377763, states[0] = -95.086560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1575648116, states[0] = 10.246786, states[40]= 0.005857
Saving checkpoint... 
Iteration: 1589579981, states[0] = -95.098296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1603519341, states[0] = 22.233554, states[40]= 0.012246
Saving checkpoint... 
Iteration: 1617330270, states[0] = 18.300622, states[40]= 0.007294
Saving checkpoint... 
Iteration: 1631380645, states[0] = -95.244396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1645241370, states[0] = 13.401880, states[40]= 0.006188
Saving checkpoint... 
Iteration: 1659158134, states[0] = -94.992830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1668893987, states[0] = -95.254861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1683114338, states[0] = -46.830814, states[40]= 0.000056
Saving checkpoint... 
Iteration: 1697363294, states[0] = -95.230539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1711146051, states[0] = -95.212748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1724549914, states[0] = -94.244309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1737872530, states[0] = -95.238860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1751621145, states[0] = -95.180185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1765706968, states[0] = -95.157189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1779721232, states[0] = -55.360511, states[40]= 0.000015
Saving checkpoint... 
Iteration: 1793563100, states[0] = -95.050576, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1807180477, states[0] = -94.747598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1821435310, states[0] = -95.005218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1835112379, states[0] = -25.765060, states[40]= 0.000753
Saving checkpoint... 
Iteration: 1848845467, states[0] = -94.954933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1862972184, states[0] = -94.985587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1876591084, states[0] = -6.635390, states[40]= 0.003053
Saving checkpoint... 
Iteration: 1891000144, states[0] = -77.291214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1904977765, states[0] = -94.978300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1919050121, states[0] = 13.433242, states[40]= 0.005087
Saving checkpoint... 
Iteration: 1932960389, states[0] = -94.973738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1946621016, states[0] = -31.951639, states[40]= 0.000432
Saving checkpoint... 
Iteration: 1960409546, states[0] = -94.962015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1974360151, states[0] = -94.944803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1988663404, states[0] = -82.371355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2003057416, states[0] = 10.714796, states[40]= 0.004998
Saving checkpoint... 
Iteration: 2017058777, states[0] = 10.185041, states[40]= 0.004983
Saving checkpoint... 
Iteration: 2030776543, states[0] = -94.888397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2044714611, states[0] = -94.803752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2058587985, states[0] = -4.141721, states[40]= 0.003568
Saving checkpoint... 
Iteration: 2072695609, states[0] = -94.767207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2086621523, states[0] = -32.345073, states[40]= 0.000413
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.853511
 - CaMKt in component CaMK (millimolar): 0.007207
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.884606
 - nass in component intracellular_ions (millimolar): 6.884667
 - ki in component intracellular_ions (millimolar): 145.090922
 - kss in component intracellular_ions (millimolar): 145.090901
 - cansr in component intracellular_ions (millimolar): 1.323362
 - cajsr in component intracellular_ions (millimolar): 1.284486
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003636
 - hf in component INa (dimensionless): 0.879159
 - hs in component INa (dimensionless): 0.879155
 - j in component INa (dimensionless): 0.879126
 - hsp in component INa (dimensionless): 0.724247
 - jp in component INa (dimensionless): 0.879107
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.706826
 - hLp in component INaL (dimensionless): 0.445279
 - a in component Ito (dimensionless): 0.000625
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.612424
 - ap in component Ito (dimensionless): 0.000319
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.685241
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.927119
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999855
 - jca in component ICaL (dimensionless): 0.999973
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001652
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.353793
 - xs1 in component IKs (dimensionless): 0.257017
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997350
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
17:57:24 (1368): called boinc_finish(0)

</stderr_txt>
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