𝕏

Task 54826785

Name HuVeMOp_20240626114313200281_ORdGradInc_k_24-Pueyo_APDR-conf_723_0
Workunit 26032637
Created 26 Jun 2024, 9:44:12 UTC
Sent 26 Jun 2024, 12:48:16 UTC
Report deadline 29 Jun 2024, 22:24:16 UTC
Received 27 Jun 2024, 5:35:37 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 233433
Run time 2 hours 36 min 36 sec
CPU time 2 hours 28 min 36 sec
Validate state Valid
Credit 58.45
Device peak FLOPS 3.98 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.43 MB
Peak swap size 32.60 GB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626114313200281_ORdGradInc_k_24-Pueyo_APDR-conf_723.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626114313200281_ORdGradInc_k_24-Pueyo_APDR-conf_723_0_r1843015896_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626114313200281_ORdGradInc_k_24-Pueyo_APDR-conf_723_0_r1843015896_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 123.327648
     * GNaL_b in INaL: 0.006172
     * Gto_b in Ito: 0.083089
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.033745
     * GKs_b in IKs: 0.001909
     * GK1_b in IK1: 0.143085
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 64.471001
     * GKb_b in IKb: 0.003979
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.044598
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11097872, states[0] = -25.189362, states[40]= 0.000638
Saving checkpoint... 
Iteration: 23160829, states[0] = -94.142308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 31722995, states[0] = -94.907079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 40127437, states[0] = -54.689587, states[40]= 0.000012
Saving checkpoint... 
Iteration: 49166418, states[0] = -94.560618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58706675, states[0] = -94.855458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 69680943, states[0] = -94.790288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 81402495, states[0] = -95.023594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 91612785, states[0] = -37.436254, states[40]= 0.000174
Saving checkpoint... 
Iteration: 101616531, states[0] = -41.253256, states[40]= 0.000101
Saving checkpoint... 
Iteration: 112701038, states[0] = -94.830857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 123471609, states[0] = -95.032875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 135272863, states[0] = -94.940246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 147601767, states[0] = -26.087078, states[40]= 0.000620
Saving checkpoint... 
Iteration: 159764911, states[0] = -94.930570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 172783363, states[0] = -94.949531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 187622605, states[0] = -47.582670, states[40]= 0.000038
Saving checkpoint... 
Iteration: 202390191, states[0] = -95.011583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 217102351, states[0] = -26.612841, states[40]= 0.000595
Saving checkpoint... 
Iteration: 231286015, states[0] = -94.951463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 245409270, states[0] = -95.017197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260060130, states[0] = 5.976479, states[40]= 0.004863
Saving checkpoint... 
Iteration: 274841185, states[0] = -94.990458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 289126329, states[0] = -51.720455, states[40]= 0.000020
Saving checkpoint... 
Iteration: 304013633, states[0] = 22.201099, states[40]= 0.025567
Saving checkpoint... 
Iteration: 318278668, states[0] = -94.944262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 330626067, states[0] = -51.424510, states[40]= 0.000021
Saving checkpoint... 
Iteration: 343524583, states[0] = 19.602723, states[40]= 0.007770
Saving checkpoint... 
Iteration: 355728372, states[0] = -94.878772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 367301703, states[0] = -94.964652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 379949422, states[0] = -95.026373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 394839358, states[0] = -94.989372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 409765148, states[0] = -94.929777, states[40]= 0.000000
Saving checkpoint... 
Iteration: 424137776, states[0] = -64.971360, states[40]= 0.000002
Saving checkpoint... 
Iteration: 438911935, states[0] = -95.017741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 453617291, states[0] = -41.790692, states[40]= 0.000093
Saving checkpoint... 
Iteration: 468182034, states[0] = -94.781214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 482447376, states[0] = -95.025919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 496463680, states[0] = -95.028857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 511012333, states[0] = 22.520907, states[40]= 0.033156
Saving checkpoint... 
Iteration: 525414759, states[0] = -95.018451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 539779353, states[0] = -94.944806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 554377911, states[0] = -95.006764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 568916672, states[0] = -95.018929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 583438232, states[0] = -95.024000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 597317200, states[0] = -94.975825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 611565741, states[0] = 3.268857, states[40]= 0.004672
Saving checkpoint... 
Iteration: 626318178, states[0] = -94.976465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 640487570, states[0] = -95.032346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 654956333, states[0] = -95.027497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 669671407, states[0] = -94.684797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 684446136, states[0] = -95.025562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 699172564, states[0] = -94.708317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 713587651, states[0] = -12.110071, states[40]= 0.001959
Saving checkpoint... 
Iteration: 726273710, states[0] = -94.938963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 741011449, states[0] = 22.772398, states[40]= 0.040012
Saving checkpoint... 
Iteration: 755822319, states[0] = -94.979104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 770225471, states[0] = -94.873647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 784771729, states[0] = -94.936836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 799494785, states[0] = -95.033183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 814324712, states[0] = -94.980588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 827571483, states[0] = 0.160881, states[40]= 0.004337
Saving checkpoint... 
Iteration: 842227026, states[0] = -94.876243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 857006033, states[0] = 26.984925, states[40]= 0.124751
Saving checkpoint... 
Iteration: 871706053, states[0] = -94.837282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 886543739, states[0] = 12.930860, states[40]= 0.005281
Saving checkpoint... 
Iteration: 900847051, states[0] = -94.993112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 915290057, states[0] = -94.954610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 929454251, states[0] = -95.026966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 944230947, states[0] = -94.882660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 958835040, states[0] = -94.986660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 973571418, states[0] = 0.198668, states[40]= 0.004342
Saving checkpoint... 
Iteration: 987927216, states[0] = -95.021306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1001417631, states[0] = -95.018935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1016260784, states[0] = -94.924334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031029320, states[0] = 18.180937, states[40]= 0.006565
Saving checkpoint... 
Iteration: 1045871179, states[0] = -95.003881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1060156047, states[0] = -90.356784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1074880724, states[0] = -95.007513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1089717065, states[0] = -94.858519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1104502360, states[0] = 43.864591, states[40]= 0.090307
Saving checkpoint... 
Iteration: 1119223871, states[0] = -94.870695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1133150943, states[0] = -83.724333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1147864337, states[0] = -95.000997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1162727766, states[0] = -94.877303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1177585233, states[0] = -9.882989, states[40]= 0.002398
Saving checkpoint... 
Iteration: 1191706991, states[0] = -94.838998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1205510739, states[0] = 23.007345, states[40]= 0.046758
Saving checkpoint... 
Iteration: 1220299995, states[0] = -94.962813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1234998362, states[0] = -95.033374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1249128379, states[0] = -54.033728, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1263599907, states[0] = -24.170618, states[40]= 0.000713
Saving checkpoint... 
Iteration: 1278264363, states[0] = -94.928386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1292932396, states[0] = -95.022327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1307310074, states[0] = -94.970444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1321688900, states[0] = -94.799633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1335656347, states[0] = -90.637319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1350101708, states[0] = -25.962735, states[40]= 0.000626
Saving checkpoint... 
Iteration: 1363633494, states[0] = -59.886561, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1378352739, states[0] = -94.995632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1393216810, states[0] = -94.857876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1408096422, states[0] = -20.704365, states[40]= 0.000909
Saving checkpoint... 
Iteration: 1422321937, states[0] = -94.978484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437168420, states[0] = -94.579468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1451350116, states[0] = -94.994324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1465744381, states[0] = -94.902723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1479936699, states[0] = -95.023169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1494170715, states[0] = -94.666615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1508996496, states[0] = -95.296628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1523648958, states[0] = -95.275553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1537667286, states[0] = -95.140652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1552311414, states[0] = -56.910749, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1566836318, states[0] = -95.293202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1581342754, states[0] = 10.125063, states[40]= 0.006025
Saving checkpoint... 
Iteration: 1595472035, states[0] = -11.307767, states[40]= 0.002375
Saving checkpoint... 
Iteration: 1608687022, states[0] = -28.403215, states[40]= 0.000511
Saving checkpoint... 
Iteration: 1623331581, states[0] = 15.615289, states[40]= 0.007163
Saving checkpoint... 
Iteration: 1637924886, states[0] = -95.288205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1651720916, states[0] = -95.282661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1666242969, states[0] = 9.912607, states[40]= 0.006009
Saving checkpoint... 
Iteration: 1679989560, states[0] = -95.357499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1694562955, states[0] = -95.157904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1709202883, states[0] = -47.198309, states[40]= 0.000043
Saving checkpoint... 
Iteration: 1723484588, states[0] = -95.353987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1737670765, states[0] = -10.135078, states[40]= 0.002638
Saving checkpoint... 
Iteration: 1751582657, states[0] = -95.209944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1765779588, states[0] = -95.350062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1779893166, states[0] = -95.360342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1793849075, states[0] = -95.054540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1808061875, states[0] = 3.742065, states[40]= 0.004810
Saving checkpoint... 
Iteration: 1821754873, states[0] = -94.964966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1836461164, states[0] = -95.059749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1851089355, states[0] = -14.716750, states[40]= 0.001534
Saving checkpoint... 
Iteration: 1865710736, states[0] = -94.860313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1879762887, states[0] = -94.935774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1893740548, states[0] = -94.903324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1906227870, states[0] = -94.881532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1919858600, states[0] = -95.001007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1934267810, states[0] = -94.933898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1948406696, states[0] = -95.016727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1963002651, states[0] = 41.463452, states[40]= 0.102997
Saving checkpoint... 
Iteration: 1977135426, states[0] = -62.188870, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1990597117, states[0] = -21.415559, states[40]= 0.000863
Saving checkpoint... 
Iteration: 2005099698, states[0] = -23.975948, states[40]= 0.000723
Saving checkpoint... 
Iteration: 2019204269, states[0] = -94.833126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2033866864, states[0] = -95.001638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2047949251, states[0] = -95.025437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2062022827, states[0] = 20.078916, states[40]= 0.008527
Saving checkpoint... 
Iteration: 2076265437, states[0] = -94.929156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2089906600, states[0] = -95.015303, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.908931
 - CaMKt in component CaMK (millimolar): 0.006671
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.706030
 - nass in component intracellular_ions (millimolar): 6.706090
 - ki in component intracellular_ions (millimolar): 145.275156
 - kss in component intracellular_ions (millimolar): 145.275135
 - cansr in component intracellular_ions (millimolar): 1.298808
 - cajsr in component intracellular_ions (millimolar): 1.261794
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003616
 - hf in component INa (dimensionless): 0.880124
 - hs in component INa (dimensionless): 0.880119
 - j in component INa (dimensionless): 0.880089
 - hsp in component INa (dimensionless): 0.726061
 - jp in component INa (dimensionless): 0.880070
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.711333
 - hLp in component INaL (dimensionless): 0.455870
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.627558
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.703594
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.939577
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999900
 - jca in component ICaL (dimensionless): 0.999981
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001558
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.332585
 - xs1 in component IKs (dimensionless): 0.231105
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997335
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
01:21:23 (48526): called boinc_finish(0)

</stderr_txt>
]]>


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