𝕏

Task 54822616

Name HuVeMOp_20240626113555201639_ORdGradInc_k_24-BASE_MID-conf_178_1
Workunit 26030554
Created 26 Jun 2024, 9:41:47 UTC
Sent 26 Jun 2024, 12:07:39 UTC
Report deadline 29 Jun 2024, 12:07:39 UTC
Received 27 Jun 2024, 10:07:00 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 239842
Run time 1 hours 1 min 54 sec
CPU time 52 min 18 sec
Validate state Invalid
Credit 0.00
Device peak FLOPS 6.87 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.82 MB
Peak swap size 3.88 MB
Peak disk usage 0.34 MB

Stderr output

<core_client_version>7.20.5</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626113555201639_ORdGradInc_k_24-BASE_MID-conf_178.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626113555201639_ORdGradInc_k_24-BASE_MID-conf_178_1_r996172757_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626113555201639_ORdGradInc_k_24-BASE_MID-conf_178_1_r996172757_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 14
     * GNa in INa: 103.582520
     * GNaL_b in INaL: 0.005931
     * Gto_b in Ito: 0.084945
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.032782
     * GKs_b in IKs: 0.001877
     * GK1_b in IK1: 0.172273
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 66.472152
     * GKb_b in IKb: 0.003869
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.050736
     * celltype in environment: 2.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 8506001, states[0] = 22.601602, states[40]= 0.285687
Saving checkpoint... 
Iteration: 17147153, states[0] = -18.273830, states[40]= 0.000116
Saving checkpoint... 
Iteration: 24859448, states[0] = -86.852182, states[40]= 0.000001
Saving checkpoint... 
Iteration: 33458799, states[0] = -86.954151, states[40]= 0.000002
Saving checkpoint... 
Iteration: 42239080, states[0] = -86.497086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 50768222, states[0] = -86.660228, states[40]= 0.000001
Saving checkpoint... 
Iteration: 59477703, states[0] = -87.000490, states[40]= 0.000002
Saving checkpoint... 
Iteration: 67752873, states[0] = -86.608375, states[40]= 0.000001
Saving checkpoint... 
Iteration: 76245297, states[0] = -86.574872, states[40]= 0.000001
Saving checkpoint... 
Iteration: 84979927, states[0] = -87.021809, states[40]= 0.000002
Saving checkpoint... 
Iteration: 93704116, states[0] = -86.246778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 102016936, states[0] = 30.641330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 110658806, states[0] = -41.457500, states[40]= 0.000205
Saving checkpoint... 
Iteration: 118704978, states[0] = -86.283654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 126988536, states[0] = -87.037362, states[40]= 0.000002
Saving checkpoint... 
Iteration: 135889383, states[0] = -86.977938, states[40]= 0.000002
Saving checkpoint... 
Iteration: 144302019, states[0] = -86.826273, states[40]= 0.000001
Saving checkpoint... 
Iteration: 152905455, states[0] = -86.993739, states[40]= 0.000002
Saving checkpoint... 
Iteration: 161718884, states[0] = -86.422236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170044894, states[0] = 27.905895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 178402603, states[0] = -86.991397, states[40]= 0.000002
Saving checkpoint... 
Iteration: 186765864, states[0] = -86.699236, states[40]= 0.000001
Saving checkpoint... 
Iteration: 195132356, states[0] = -19.203987, states[40]= 0.000182
Saving checkpoint... 
Iteration: 203700447, states[0] = -86.187538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 211915076, states[0] = -87.000461, states[40]= 0.000002
Saving checkpoint... 
Iteration: 220618819, states[0] = -7.516894, states[40]= 0.000146
Saving checkpoint... 
Iteration: 229474903, states[0] = -87.032598, states[40]= 0.000002
Saving checkpoint... 
Iteration: 237795923, states[0] = -86.806818, states[40]= 0.000001
Saving checkpoint... 
Iteration: 246772728, states[0] = -86.725439, states[40]= 0.000001
Saving checkpoint... 
Iteration: 255458519, states[0] = -87.024337, states[40]= 0.000002
Saving checkpoint... 
Iteration: 264048687, states[0] = 26.777757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 273048369, states[0] = 26.874576, states[40]= 0.000000
Saving checkpoint... 
Iteration: 281044393, states[0] = 28.022520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 289259471, states[0] = -86.665225, states[40]= 0.000001
Saving checkpoint... 
Iteration: 298136025, states[0] = -22.343310, states[40]= 0.000251
Saving checkpoint... 
Iteration: 306412468, states[0] = -86.993480, states[40]= 0.000002
Saving checkpoint... 
Iteration: 314731292, states[0] = -86.504394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 323650433, states[0] = -34.584353, states[40]= 0.000352
Saving checkpoint... 
Iteration: 331948107, states[0] = -87.014896, states[40]= 0.000002
Saving checkpoint... 
Iteration: 340457094, states[0] = -87.018868, states[40]= 0.000002
Saving checkpoint... 
Iteration: 349594120, states[0] = 7.828078, states[40]= 0.000026
Saving checkpoint... 
Iteration: 358160060, states[0] = -43.886953, states[40]= 0.000166
Saving checkpoint... 
Iteration: 366516492, states[0] = 30.431215, states[40]= -0.000000
Saving checkpoint... 
Iteration: 375368074, states[0] = -86.944655, states[40]= 0.000002
Saving checkpoint... 
Iteration: 383502858, states[0] = 18.032587, states[40]= 1.387833
Saving checkpoint... 
Iteration: 391595894, states[0] = 6.919341, states[40]= 0.000031
Saving checkpoint... 
Iteration: 400823257, states[0] = -86.867653, states[40]= 0.000002
Saving checkpoint... 
Iteration: 408802454, states[0] = -86.815965, states[40]= 0.000001
Saving checkpoint... 
Iteration: 417158775, states[0] = -42.572856, states[40]= 0.000189
Saving checkpoint... 
Iteration: 425820258, states[0] = -86.859571, states[40]= 0.000002
Saving checkpoint... 
Iteration: 434134091, states[0] = -20.724369, states[40]= 0.000210
Saving checkpoint... 
Iteration: 442562667, states[0] = 21.912299, states[40]= 0.000001
Saving checkpoint... 
Iteration: 451352610, states[0] = -86.918513, states[40]= 0.000002
Saving checkpoint... 
Iteration: 459909328, states[0] = -86.982141, states[40]= 0.000002
Saving checkpoint... 
Iteration: 468540348, states[0] = 29.060687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 477221804, states[0] = -86.427841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 485874316, states[0] = -86.946006, states[40]= 0.000002
Saving checkpoint... 
Iteration: 494664489, states[0] = -48.539267, states[40]= 0.000100
Saving checkpoint... 
Iteration: 503190528, states[0] = -83.692856, states[40]= 0.000001
Saving checkpoint... 
Iteration: 511785292, states[0] = -86.756745, states[40]= 0.000001
Saving checkpoint... 
Iteration: 520329536, states[0] = -86.873818, states[40]= 0.000002
Saving checkpoint... 
Iteration: 529156594, states[0] = -40.388827, states[40]= 0.000231
Saving checkpoint... 
Iteration: 537862081, states[0] = -86.927252, states[40]= 0.000002
Saving checkpoint... 
Iteration: 546445044, states[0] = -87.000905, states[40]= 0.000002
Saving checkpoint... 
Iteration: 555108952, states[0] = -0.445606, states[40]= 0.000094
Saving checkpoint... 
Iteration: 563949767, states[0] = -87.002389, states[40]= 0.000002
Saving checkpoint... 
Iteration: 572167023, states[0] = -51.313522, states[40]= 0.000072
Saving checkpoint... 
Iteration: 580696572, states[0] = -85.888548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 589380155, states[0] = -86.946780, states[40]= 0.000002
Saving checkpoint... 
Iteration: 597765489, states[0] = -86.674515, states[40]= 0.000001
Saving checkpoint... 
Iteration: 606501269, states[0] = 33.872866, states[40]= 2.226544
Saving checkpoint... 
Iteration: 615005880, states[0] = 22.621425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 622844136, states[0] = -86.894856, states[40]= 0.000002
Saving checkpoint... 
Iteration: 631575964, states[0] = 16.420974, states[40]= 0.000003
Saving checkpoint... 
Iteration: 640235485, states[0] = -86.512287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 648332863, states[0] = -86.872930, states[40]= 0.000002
Saving checkpoint... 
Iteration: 657386148, states[0] = -86.949325, states[40]= 0.000002
Saving checkpoint... 
Iteration: 666335591, states[0] = -86.877109, states[40]= 0.000002
Saving checkpoint... 
Iteration: 674325162, states[0] = -86.855831, states[40]= 0.000002
Saving checkpoint... 
Iteration: 683277227, states[0] = -86.717534, states[40]= 0.000001
Saving checkpoint... 
Iteration: 692209276, states[0] = -86.312425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 700428147, states[0] = -86.981948, states[40]= 0.000002
Saving checkpoint... 
Iteration: 709335003, states[0] = -86.873487, states[40]= 0.000002
Saving checkpoint... 
Iteration: 717801638, states[0] = -86.795635, states[40]= 0.000001
Saving checkpoint... 
Iteration: 726079535, states[0] = 14.828475, states[40]= 0.000005
Saving checkpoint... 
Iteration: 735013131, states[0] = 29.229626, states[40]= -0.000000
Saving checkpoint... 
Iteration: 744121943, states[0] = -10.113663, states[40]= 0.000148
Saving checkpoint... 
Iteration: 752787621, states[0] = -86.750520, states[40]= 0.000001
Saving checkpoint... 
Iteration: 761632616, states[0] = -19.447549, states[40]= 0.000185
Saving checkpoint... 
Iteration: 770129245, states[0] = -16.526922, states[40]= 0.000154
Saving checkpoint... 
Iteration: 778460090, states[0] = -86.995019, states[40]= 0.000002
Saving checkpoint... 
Iteration: 787602706, states[0] = 3.270963, states[40]= 0.000058
Saving checkpoint... 
Iteration: 796117849, states[0] = -6.723769, states[40]= 0.000142
Saving checkpoint... 
Iteration: 804003544, states[0] = 17.162670, states[40]= 1.063288
Saving checkpoint... 
Iteration: 812891515, states[0] = -86.945804, states[40]= 0.000002
Saving checkpoint... 
Iteration: 821631976, states[0] = -18.894868, states[40]= 0.000176
Saving checkpoint... 
Iteration: 829838225, states[0] = -86.872457, states[40]= 0.000002
Saving checkpoint... 
Iteration: 838728690, states[0] = -86.455508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 847015492, states[0] = 30.153282, states[40]= -0.000000
Saving checkpoint... 
Iteration: 855510525, states[0] = 27.719899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 864671831, states[0] = -56.842011, states[40]= 0.000036
Saving checkpoint... 
Iteration: 873337347, states[0] = -86.868315, states[40]= 0.000002
Saving checkpoint... 
Iteration: 881559123, states[0] = 23.257294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 889969006, states[0] = -86.992458, states[40]= 0.000002
Saving checkpoint... 
Iteration: 898489888, states[0] = -86.999634, states[40]= 0.000002
Saving checkpoint... 
Iteration: 906698104, states[0] = -86.014215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 915117121, states[0] = -6.143860, states[40]= 0.000139
Saving checkpoint... 
Iteration: 924013461, states[0] = 29.385093, states[40]= -0.000000
Saving checkpoint... 
Iteration: 932300105, states[0] = -86.778751, states[40]= 0.000001
Saving checkpoint... 
Iteration: 940651376, states[0] = -35.387860, states[40]= 0.000333
Saving checkpoint... 
Iteration: 949417615, states[0] = -86.960249, states[40]= 0.000002
Saving checkpoint... 
Iteration: 957898822, states[0] = -86.944346, states[40]= 0.000002
Saving checkpoint... 
Iteration: 965888035, states[0] = -86.933445, states[40]= 0.000002
Saving checkpoint... 
Iteration: 974674131, states[0] = -59.687528, states[40]= 0.000025
Saving checkpoint... 
Iteration: 983384564, states[0] = -86.928792, states[40]= 0.000002
Saving checkpoint... 
Iteration: 991923405, states[0] = -86.961919, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1000777855, states[0] = -86.701247, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1009481993, states[0] = -86.990566, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1017946729, states[0] = -86.974623, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1026981655, states[0] = -86.989433, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1035424879, states[0] = -86.960437, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1044337617, states[0] = -86.858893, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1053504365, states[0] = 18.823547, states[40]= -0.000004
Saving checkpoint... 
Iteration: 1061829170, states[0] = -86.841585, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1070371114, states[0] = -86.908248, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1079609420, states[0] = -0.714184, states[40]= 0.000096
Saving checkpoint... 
Iteration: 1087996480, states[0] = -86.990763, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1096615302, states[0] = -4.749825, states[40]= 0.000132
Saving checkpoint... 
Iteration: 1105425519, states[0] = -86.956819, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1113540702, states[0] = 28.991439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1122236771, states[0] = -86.491772, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1131239694, states[0] = -86.509236, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1139804822, states[0] = -86.779806, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1148900806, states[0] = -86.935104, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1157703826, states[0] = -86.216173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1166065567, states[0] = 20.793913, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1174980514, states[0] = -86.980494, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1183974178, states[0] = -86.977591, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1192538091, states[0] = 29.588983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1201499098, states[0] = -86.985002, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1210372561, states[0] = -86.901923, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1219156641, states[0] = -40.359123, states[40]= 0.000229
Saving checkpoint... 
Iteration: 1227504734, states[0] = 19.920349, states[40]= -0.000000
Saving checkpoint... 
Iteration: 1236382269, states[0] = -86.911697, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1245155909, states[0] = -39.641857, states[40]= 0.000243
Saving checkpoint... 
Iteration: 1253589549, states[0] = 10.133587, states[40]= 0.000016
Saving checkpoint... 
Iteration: 1262518900, states[0] = 30.947882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1271430082, states[0] = -86.950264, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1279660801, states[0] = -44.541981, states[40]= 0.000153
Saving checkpoint... 
Iteration: 1288580320, states[0] = 14.486600, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1297611419, states[0] = -2.005435, states[40]= 0.000109
Saving checkpoint... 
Iteration: 1305999351, states[0] = -86.979066, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1314984482, states[0] = -86.973832, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1324058615, states[0] = 23.453933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1332446315, states[0] = -86.956258, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1341414353, states[0] = -86.935167, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1350293790, states[0] = -86.735466, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1358565139, states[0] = 20.968413, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1367456421, states[0] = -86.959373, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1376072777, states[0] = 17.821715, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1383916439, states[0] = -86.934312, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1392911671, states[0] = -86.930128, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1401858703, states[0] = -86.872450, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1409915659, states[0] = -86.932219, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1418552090, states[0] = 25.723564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1426975162, states[0] = -86.963985, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1434875344, states[0] = -86.892299, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1443581921, states[0] = 13.756246, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1452523158, states[0] = 31.306496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1461048381, states[0] = 26.897925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1469895065, states[0] = -86.911294, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1478472373, states[0] = -86.959952, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1487116613, states[0] = -5.710593, states[40]= 0.000136
Saving checkpoint... 
Iteration: 1495834469, states[0] = -86.826794, states[40]= 0.000002
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.843986
 - CaMKt in component CaMK (millimolar): 0.025290
 - cass in component intracellular_ions (millimolar): 0.000093
 - nai in component intracellular_ions (millimolar): 8.216848
 - nass in component intracellular_ions (millimolar): 8.217003
 - ki in component intracellular_ions (millimolar): 143.154433
 - kss in component intracellular_ions (millimolar): 143.154394
 - cansr in component intracellular_ions (millimolar): 2.067425
 - cajsr in component intracellular_ions (millimolar): 2.003879
 - cai in component intracellular_ions (millimolar): 0.000096
 - m in component INa (dimensionless): 0.008148
 - hf in component INa (dimensionless): 0.661153
 - hs in component INa (dimensionless): 0.661125
 - j in component INa (dimensionless): 0.660966
 - hsp in component INa (dimensionless): 0.413214
 - jp in component INa (dimensionless): 0.660852
 - mL in component INaL (dimensionless): 0.000229
 - hL in component INaL (dimensionless): 0.458458
 - hLp in component INaL (dimensionless): 0.225228
 - a in component Ito (dimensionless): 0.001073
 - iF in component Ito (dimensionless): 0.999466
 - iS in component Ito (dimensionless): 0.538837
 - ap in component Ito (dimensionless): 0.000547
 - iFp in component Ito (dimensionless): 0.999466
 - iSp in component Ito (dimensionless): 0.583252
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.880540
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999646
 - jca in component ICaL (dimensionless): 0.999944
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003912
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.502453
 - xs1 in component IKs (dimensionless): 0.328537
 - xs2 in component IKs (dimensionless): 0.000217
 - xk1 in component IK1 (dimensionless): 0.997021
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000002
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000002
04:46:28 (2844049): called boinc_finish(0)

</stderr_txt>
]]>


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