𝕏

Task 54822257

Name HuVeMOp_20240626113555201639_ORdGradInc_k_24-Pieske_500-conf_76_1
Workunit 26030375
Created 26 Jun 2024, 9:41:31 UTC
Sent 26 Jun 2024, 12:07:52 UTC
Report deadline 29 Jun 2024, 12:07:52 UTC
Received 27 Jun 2024, 18:47:26 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 239842
Run time 1 hours 2 min 17 sec
CPU time 52 min 54 sec
Validate state Valid
Credit 40.48
Device peak FLOPS 6.87 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.47 MB
Peak swap size 3.69 MB
Peak disk usage 0.18 MB

Stderr output

<core_client_version>7.20.5</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626113555201639_ORdGradInc_k_24-Pieske_500-conf_76.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626113555201639_ORdGradInc_k_24-Pieske_500-conf_76_1_r1054814144_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626113555201639_ORdGradInc_k_24-Pieske_500-conf_76_1_r1054814144_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.985972
     * GNaL_b in INaL: 0.008492
     * Gto_b in Ito: 0.079507
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032448
     * GKs_b in IKs: 0.001811
     * GK1_b in IK1: 0.170507
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 61.584156
     * GKb_b in IKb: 0.003954
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035504
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 6000.000000
     * CL_0 in membrane: 500.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499750000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 8652426, states[0] = -87.302115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 17260736, states[0] = 24.095323, states[40]= 0.039404
Saving checkpoint... 
Iteration: 26415050, states[0] = -87.314674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 34806662, states[0] = 1.946910, states[40]= 0.005306
Saving checkpoint... 
Iteration: 43647735, states[0] = -87.261730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 52879826, states[0] = -85.832576, states[40]= 0.000000
Saving checkpoint... 
Iteration: 61150728, states[0] = -87.276810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 69918167, states[0] = -87.328699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 78874142, states[0] = -81.350689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 86907512, states[0] = -87.300778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 95539263, states[0] = 12.531253, states[40]= 0.006216
Saving checkpoint... 
Iteration: 104386066, states[0] = -87.043945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 112743805, states[0] = -87.465205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 121545153, states[0] = 9.189056, states[40]= 0.005957
Saving checkpoint... 
Iteration: 130626942, states[0] = -84.311101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 139212834, states[0] = -87.424043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 147874048, states[0] = -81.358894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 156329977, states[0] = -22.045111, states[40]= 0.000922
Saving checkpoint... 
Iteration: 165024190, states[0] = 19.805605, states[40]= 0.007980
Saving checkpoint... 
Iteration: 173783422, states[0] = 15.578462, states[40]= 0.006578
Saving checkpoint... 
Iteration: 182079892, states[0] = -21.949123, states[40]= 0.000929
Saving checkpoint... 
Iteration: 190261403, states[0] = 23.865915, states[40]= 0.033972
Saving checkpoint... 
Iteration: 199007737, states[0] = 25.271594, states[40]= 0.077018
Saving checkpoint... 
Iteration: 207795859, states[0] = 8.763909, states[40]= 0.005927
Saving checkpoint... 
Iteration: 216501737, states[0] = 40.432394, states[40]= 0.085805
Saving checkpoint... 
Iteration: 224974162, states[0] = -87.441241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 233582494, states[0] = -25.031036, states[40]= 0.000727
Saving checkpoint... 
Iteration: 242007790, states[0] = 25.239597, states[40]= 0.076113
Saving checkpoint... 
Iteration: 250802473, states[0] = 4.638976, states[40]= 0.005610
Saving checkpoint... 
Iteration: 259466377, states[0] = -87.429804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 268256526, states[0] = 26.198711, states[40]= 0.099883
Saving checkpoint... 
Iteration: 276719406, states[0] = -87.434351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 285439008, states[0] = -87.380539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 294028596, states[0] = 17.897104, states[40]= 0.007084
Saving checkpoint... 
Iteration: 302289179, states[0] = 12.558848, states[40]= 0.006220
Saving checkpoint... 
Iteration: 310783247, states[0] = 15.664994, states[40]= 0.006592
Saving checkpoint... 
Iteration: 319203462, states[0] = -87.408407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 327253647, states[0] = 31.722684, states[40]= 0.142987
Saving checkpoint... 
Iteration: 336034288, states[0] = 15.139176, states[40]= 0.006512
Saving checkpoint... 
Iteration: 344461798, states[0] = -87.422511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 352815212, states[0] = -5.369067, states[40]= 0.003945
Saving checkpoint... 
Iteration: 361811608, states[0] = -2.113231, states[40]= 0.004669
Saving checkpoint... 
Iteration: 370107301, states[0] = -55.578315, states[40]= 0.000014
Saving checkpoint... 
Iteration: 378941808, states[0] = -87.386203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 387961593, states[0] = -87.422132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396717441, states[0] = -87.431281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 405244605, states[0] = -87.466612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 414508886, states[0] = 24.691359, states[40]= 0.059397
Saving checkpoint... 
Iteration: 423065904, states[0] = -6.044463, states[40]= 0.003779
Saving checkpoint... 
Iteration: 431453130, states[0] = -87.407693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 440680278, states[0] = -87.361224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 449564100, states[0] = -4.318237, states[40]= 0.004194
Saving checkpoint... 
Iteration: 458202500, states[0] = -87.406536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 467618902, states[0] = -73.353034, states[40]= 0.000001
Saving checkpoint... 
Iteration: 476519105, states[0] = 21.688530, states[40]= 0.010695
Saving checkpoint... 
Iteration: 485238188, states[0] = -87.459138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 494038611, states[0] = 12.867143, states[40]= 0.006249
Saving checkpoint... 
Iteration: 502776074, states[0] = 19.016558, states[40]= 0.007515
Saving checkpoint... 
Iteration: 511453329, states[0] = -87.407960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 520422095, states[0] = -87.341508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 528612544, states[0] = -63.082427, states[40]= 0.000004
Saving checkpoint... 
Iteration: 537393505, states[0] = -87.242060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 546208531, states[0] = -87.416911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 554923676, states[0] = -87.345392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 563304299, states[0] = 3.412543, states[40]= 0.005491
Saving checkpoint... 
Iteration: 572262745, states[0] = 23.512853, states[40]= 0.025869
Saving checkpoint... 
Iteration: 580593533, states[0] = -38.043761, states[40]= 0.000182
Saving checkpoint... 
Iteration: 589160504, states[0] = -87.310704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 597729546, states[0] = -87.448173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 606504963, states[0] = 28.335624, states[40]= 0.131029
Saving checkpoint... 
Iteration: 614784918, states[0] = 14.816794, states[40]= 0.006467
Saving checkpoint... 
Iteration: 623701148, states[0] = -87.403906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 631880053, states[0] = -86.020644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 640352935, states[0] = -49.744172, states[40]= 0.000034
Saving checkpoint... 
Iteration: 649338301, states[0] = -31.863792, states[40]= 0.000387
Saving checkpoint... 
Iteration: 657821195, states[0] = -11.707510, states[40]= 0.002394
Saving checkpoint... 
Iteration: 666255821, states[0] = 26.987215, states[40]= 0.114402
Saving checkpoint... 
Iteration: 675216036, states[0] = -87.428831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 683739039, states[0] = -87.459931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 692197470, states[0] = -87.396978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 700875757, states[0] = -83.295340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 709455244, states[0] = -87.411114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 718037984, states[0] = 13.204939, states[40]= 0.006282
Saving checkpoint... 
Iteration: 726658991, states[0] = -87.306257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 735025338, states[0] = 19.329594, states[40]= 0.007678
Saving checkpoint... 
Iteration: 743663699, states[0] = -87.319365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 752030907, states[0] = 16.813285, states[40]= 0.006805
Saving checkpoint... 
Iteration: 760147177, states[0] = -87.265727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 768479738, states[0] = -87.448238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 776790063, states[0] = 12.074916, states[40]= 0.006177
Saving checkpoint... 
Iteration: 785225975, states[0] = -87.443164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 793675936, states[0] = -87.350627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 802285893, states[0] = 14.311667, states[40]= 0.006403
Saving checkpoint... 
Iteration: 810472418, states[0] = -87.438152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 819014013, states[0] = 23.185013, states[40]= 0.020499
Saving checkpoint... 
Iteration: 827630739, states[0] = -86.243368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 836034086, states[0] = 15.242094, states[40]= 0.006527
Saving checkpoint... 
Iteration: 844664434, states[0] = -87.321244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 853300820, states[0] = 5.712264, states[40]= 0.005702
Saving checkpoint... 
Iteration: 861774834, states[0] = 19.540132, states[40]= 0.007802
Saving checkpoint... 
Iteration: 870187323, states[0] = -87.376342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 878670944, states[0] = -87.338217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 887157366, states[0] = -87.301370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 895699691, states[0] = -87.400926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 904353456, states[0] = -50.425330, states[40]= 0.000030
Saving checkpoint... 
Iteration: 912865499, states[0] = -67.687738, states[40]= 0.000002
Saving checkpoint... 
Iteration: 920969837, states[0] = -87.434284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 929391316, states[0] = -87.216605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 937760572, states[0] = 24.101451, states[40]= 0.040650
Saving checkpoint... 
Iteration: 945893942, states[0] = -87.245317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 954725111, states[0] = -87.441786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 963242033, states[0] = -87.463104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 971831657, states[0] = -24.041999, states[40]= 0.000786
Saving checkpoint... 
Iteration: 980288221, states[0] = 13.077715, states[40]= 0.006269
Saving checkpoint... 
Iteration: 988381135, states[0] = -86.353790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 996722776, states[0] = -87.438458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1005397031, states[0] = -87.264734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1013818196, states[0] = -8.396510, states[40]= 0.003187
Saving checkpoint... 
Iteration: 1022255653, states[0] = 27.212692, states[40]= 0.117841
Saving checkpoint... 
Iteration: 1030742743, states[0] = -87.463838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1038710822, states[0] = -87.420162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1046913474, states[0] = -87.318417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1055480263, states[0] = -87.448611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1063746182, states[0] = -87.467624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1072045531, states[0] = 8.957837, states[40]= 0.005941
Saving checkpoint... 
Iteration: 1080882011, states[0] = -86.558544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1089172204, states[0] = -87.341152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1097336451, states[0] = -29.689917, states[40]= 0.000484
Saving checkpoint... 
Iteration: 1105723300, states[0] = -87.439083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1113721478, states[0] = -87.436467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1121821051, states[0] = -11.543220, states[40]= 0.002431
Saving checkpoint... 
Iteration: 1130612190, states[0] = -62.550095, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1138623186, states[0] = -80.215809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1146808057, states[0] = 0.718264, states[40]= 0.005156
Saving checkpoint... 
Iteration: 1155345647, states[0] = -40.584398, states[40]= 0.000128
Saving checkpoint... 
Iteration: 1163861523, states[0] = -61.560826, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1173019138, states[0] = 21.677760, states[40]= 0.010665
Saving checkpoint... 
Iteration: 1181558939, states[0] = 0.044832, states[40]= 0.005053
Saving checkpoint... 
Iteration: 1189931799, states[0] = -87.363865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1198514028, states[0] = 23.181165, states[40]= 0.020446
Saving checkpoint... 
Iteration: 1206882664, states[0] = -86.680773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1215236819, states[0] = -87.456691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1223596518, states[0] = -41.644022, states[40]= 0.000111
Saving checkpoint... 
Iteration: 1231663042, states[0] = -87.317033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1240371134, states[0] = -77.081864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1249260434, states[0] = 24.143016, states[40]= 0.041906
Saving checkpoint... 
Iteration: 1257355064, states[0] = -52.552075, states[40]= 0.000022
Saving checkpoint... 
Iteration: 1266103232, states[0] = -50.131236, states[40]= 0.000032
Saving checkpoint... 
Iteration: 1274852101, states[0] = -48.659704, states[40]= 0.000040
Saving checkpoint... 
Iteration: 1282903708, states[0] = -87.289816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1290989369, states[0] = -87.459655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1299681416, states[0] = -87.362876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1307971726, states[0] = -87.436612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1316354065, states[0] = -51.226053, states[40]= 0.000027
Saving checkpoint... 
Iteration: 1325485979, states[0] = -87.455546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1334114658, states[0] = -66.342717, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1341854085, states[0] = -51.252416, states[40]= 0.000027
Saving checkpoint... 
Iteration: 1350670754, states[0] = -87.337215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1358789058, states[0] = 12.625119, states[40]= 0.006226
Saving checkpoint... 
Iteration: 1367542382, states[0] = 10.779503, states[40]= 0.006073
Saving checkpoint... 
Iteration: 1376400442, states[0] = -87.278668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1384340018, states[0] = -33.881684, states[40]= 0.000308
Saving checkpoint... 
Iteration: 1392484001, states[0] = -87.453024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1401233766, states[0] = -87.452720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1409270443, states[0] = 21.230145, states[40]= 0.009650
Saving checkpoint... 
Iteration: 1417276046, states[0] = 19.028908, states[40]= 0.007520
Saving checkpoint... 
Iteration: 1425883696, states[0] = -86.832071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1434016255, states[0] = 22.571981, states[40]= 0.014555
Saving checkpoint... 
Iteration: 1442478549, states[0] = -87.445925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1451543251, states[0] = 10.284218, states[40]= 0.006036
Saving checkpoint... 
Iteration: 1459441162, states[0] = -87.383698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1468038181, states[0] = 13.099437, states[40]= 0.006271
Saving checkpoint... 
Iteration: 1476856597, states[0] = -54.615476, states[40]= 0.000016
Saving checkpoint... 
Iteration: 1484990371, states[0] = -87.460615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493494694, states[0] = -87.465518, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -87.346971
 - CaMKt in component CaMK (millimolar): 0.020361
 - cass in component intracellular_ions (millimolar): 0.000096
 - nai in component intracellular_ions (millimolar): 7.037559
 - nass in component intracellular_ions (millimolar): 7.037661
 - ki in component intracellular_ions (millimolar): 144.914444
 - kss in component intracellular_ions (millimolar): 144.914416
 - cansr in component intracellular_ions (millimolar): 1.448513
 - cajsr in component intracellular_ions (millimolar): 1.225975
 - cai in component intracellular_ions (millimolar): 0.000095
 - m in component INa (dimensionless): 0.007747
 - hf in component INa (dimensionless): 0.679418
 - hs in component INa (dimensionless): 0.679321
 - j in component INa (dimensionless): 0.678647
 - hsp in component INa (dimensionless): 0.433136
 - jp in component INa (dimensionless): 0.676666
 - mL in component INaL (dimensionless): 0.000208
 - hL in component INaL (dimensionless): 0.387209
 - hLp in component INaL (dimensionless): 0.181392
 - a in component Ito (dimensionless): 0.001038
 - iF in component Ito (dimensionless): 0.999511
 - iS in component Ito (dimensionless): 0.290861
 - ap in component Ito (dimensionless): 0.000529
 - iFp in component Ito (dimensionless): 0.999511
 - iSp in component Ito (dimensionless): 0.337533
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.852784
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.990457
 - jca in component ICaL (dimensionless): 0.991013
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004388
 - xrf in component IKr (dimensionless): 0.001859
 - xrs in component IKr (dimensionless): 0.680403
 - xs1 in component IKs (dimensionless): 0.388978
 - xs2 in component IKs (dimensionless): 0.000214
 - xk1 in component IK1 (dimensionless): 0.996898
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
13:47:15 (2968537): called boinc_finish(0)

</stderr_txt>
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