𝕏

Task 54819930

Name HuVeMOp_20240623002254827301_ORdGradInc_k_23-Pueyo_APDR-conf_67_2
Workunit 25810428
Created 26 Jun 2024, 9:40:09 UTC
Sent 26 Jun 2024, 11:44:15 UTC
Report deadline 29 Jun 2024, 21:20:15 UTC
Received 28 Jun 2024, 11:01:07 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241457
Run time 2 hours 51 min 16 sec
CPU time 2 hours 49 min 36 sec
Validate state Valid
Credit 57.43
Device peak FLOPS 3.42 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.79 MB
Peak swap size 6.14 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623002254827301_ORdGradInc_k_23-Pueyo_APDR-conf_67.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623002254827301_ORdGradInc_k_23-Pueyo_APDR-conf_67_2_r1758999444_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623002254827301_ORdGradInc_k_23-Pueyo_APDR-conf_67_2_r1758999444_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 71.340105
     * GNaL_b in INaL: 0.003608
     * Gto_b in Ito: 0.086503
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.028979
     * GKs_b in IKs: 0.001871
     * GK1_b in IK1: 0.216411
     * Gncx_b in INaCa_i: 0.001009
     * Pnak_b in INaK: 67.975531
     * GKb_b in IKb: 0.003571
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035651
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 9504992, states[0] = 25.382920, states[40]= 0.145867
Saving checkpoint... 
Iteration: 23289760, states[0] = -94.958096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 36866713, states[0] = -94.986077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 49992378, states[0] = -95.005352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 63619046, states[0] = -33.638008, states[40]= 0.000307
Saving checkpoint... 
Iteration: 77277734, states[0] = -94.930737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 90896439, states[0] = -94.983285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 104516357, states[0] = 21.285176, states[40]= 0.012762
Saving checkpoint... 
Iteration: 118191782, states[0] = -94.823566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 131880158, states[0] = -94.977095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 145558638, states[0] = 8.542933, states[40]= 0.004599
Saving checkpoint... 
Iteration: 159272434, states[0] = -94.922792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 172941190, states[0] = -94.989807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 186632291, states[0] = -45.273860, states[40]= 0.000057
Saving checkpoint... 
Iteration: 200308610, states[0] = -94.947188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 214056413, states[0] = 9.409051, states[40]= 0.004612
Saving checkpoint... 
Iteration: 227675744, states[0] = -94.743831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 241275301, states[0] = -94.924711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 254899563, states[0] = -94.981300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 268594643, states[0] = -11.519880, states[40]= 0.001948
Saving checkpoint... 
Iteration: 282380141, states[0] = -94.976206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 295392015, states[0] = -94.979395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 308965670, states[0] = -94.993047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 322588312, states[0] = -6.519458, states[40]= 0.002940
Saving checkpoint... 
Iteration: 336288399, states[0] = -94.934314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 350035445, states[0] = 16.820690, states[40]= 0.004979
Saving checkpoint... 
Iteration: 363775699, states[0] = -94.924903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 377380373, states[0] = -94.976193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 391027577, states[0] = 19.131594, states[40]= 0.005713
Saving checkpoint... 
Iteration: 404664218, states[0] = -90.181066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 418279898, states[0] = -94.928102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432022378, states[0] = 20.343813, states[40]= 0.007035
Saving checkpoint... 
Iteration: 445796146, states[0] = -94.939393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 459554565, states[0] = 10.106811, states[40]= 0.004620
Saving checkpoint... 
Iteration: 473161080, states[0] = -84.305493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 486834875, states[0] = -94.959965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 496190125, states[0] = -94.819211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 509726004, states[0] = -94.873789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 523393716, states[0] = -94.979650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 536437408, states[0] = -94.988680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 550025409, states[0] = 19.674368, states[40]= 0.006114
Saving checkpoint... 
Iteration: 563763526, states[0] = -94.914536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 577358741, states[0] = -94.969228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 590557272, states[0] = 9.084140, states[40]= 0.004607
Saving checkpoint... 
Iteration: 604209689, states[0] = -94.850802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 617587380, states[0] = -5.849851, states[40]= 0.003076
Saving checkpoint... 
Iteration: 631265266, states[0] = -94.916025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 645065080, states[0] = 5.974899, states[40]= 0.004527
Saving checkpoint... 
Iteration: 658735407, states[0] = -94.885383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 672428070, states[0] = -94.986938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 686193941, states[0] = -94.825607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 699895813, states[0] = -94.980040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 709283922, states[0] = -94.930862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 723016670, states[0] = 21.270341, states[40]= 0.012202
Saving checkpoint... 
Iteration: 736766615, states[0] = -94.917122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 750501122, states[0] = 41.240750, states[40]= 0.047396
Saving checkpoint... 
Iteration: 764104241, states[0] = -19.929118, states[40]= 0.000954
Saving checkpoint... 
Iteration: 777692562, states[0] = -94.823204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 791349149, states[0] = -94.965572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 805001771, states[0] = 40.135294, states[40]= 0.103802
Saving checkpoint... 
Iteration: 818552345, states[0] = 10.930042, states[40]= 0.004630
Saving checkpoint... 
Iteration: 832134534, states[0] = -47.431450, states[40]= 0.000041
Saving checkpoint... 
Iteration: 845797896, states[0] = -94.940206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 859342066, states[0] = -94.962726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 873000338, states[0] = -53.421319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 886683450, states[0] = -94.805492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 900246236, states[0] = -94.897397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 912905467, states[0] = -94.982157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 926535963, states[0] = 16.654308, states[40]= 0.004952
Saving checkpoint... 
Iteration: 936288371, states[0] = -94.933845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 949627859, states[0] = -41.071259, states[40]= 0.000108
Saving checkpoint... 
Iteration: 963240549, states[0] = -94.891112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 976881822, states[0] = -94.976155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 990579646, states[0] = -0.974917, states[40]= 0.003928
Saving checkpoint... 
Iteration: 1004296759, states[0] = -94.939368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1017932298, states[0] = -94.987441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031695955, states[0] = -94.828713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1045352774, states[0] = -94.966742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1059129905, states[0] = -42.985806, states[40]= 0.000081
Saving checkpoint... 
Iteration: 1072846234, states[0] = -94.964235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1086552665, states[0] = 10.812239, states[40]= 0.004628
Saving checkpoint... 
Iteration: 1100196278, states[0] = -94.829197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1113981371, states[0] = -94.994348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1127708132, states[0] = -94.848050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1141376188, states[0] = -94.974410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1155086219, states[0] = -5.041802, states[40]= 0.003237
Saving checkpoint... 
Iteration: 1168817467, states[0] = -94.951159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1182447660, states[0] = -94.989847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1196128627, states[0] = -41.786478, states[40]= 0.000097
Saving checkpoint... 
Iteration: 1209790267, states[0] = -94.934943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1223530333, states[0] = 18.376347, states[40]= 0.005366
Saving checkpoint... 
Iteration: 1237144957, states[0] = -58.258610, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1250803465, states[0] = -94.943314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1264452740, states[0] = -94.990547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1277468033, states[0] = -94.992627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1291043726, states[0] = 14.025050, states[40]= 0.004705
Saving checkpoint... 
Iteration: 1304456745, states[0] = -94.991093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1318136825, states[0] = -49.696859, states[40]= 0.000028
Saving checkpoint... 
Iteration: 1331814383, states[0] = -94.949415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1345437068, states[0] = -94.988021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1359062708, states[0] = 6.949636, states[40]= 0.004561
Saving checkpoint... 
Iteration: 1372656691, states[0] = -75.011890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1386371154, states[0] = -94.972705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1400058697, states[0] = 8.536242, states[40]= 0.004599
Saving checkpoint... 
Iteration: 1409415230, states[0] = -94.983893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1423035777, states[0] = 16.714397, states[40]= 0.004962
Saving checkpoint... 
Iteration: 1436702465, states[0] = -94.838989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1450352688, states[0] = -94.966409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1464026673, states[0] = 19.364117, states[40]= 0.005863
Saving checkpoint... 
Iteration: 1477733967, states[0] = -94.883048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1491373987, states[0] = -94.973493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1504950185, states[0] = -94.670017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1518119763, states[0] = -52.993791, states[40]= 0.000017
Saving checkpoint... 
Iteration: 1531730175, states[0] = -95.121297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1545350930, states[0] = 7.883133, states[40]= 0.005272
Saving checkpoint... 
Iteration: 1558927620, states[0] = -64.882085, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1572344051, states[0] = 11.106615, states[40]= 0.005462
Saving checkpoint... 
Iteration: 1585921476, states[0] = -57.116380, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1599494894, states[0] = -95.086449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1613102161, states[0] = 38.368749, states[40]= 0.106579
Saving checkpoint... 
Iteration: 1626758014, states[0] = -95.012510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1640467755, states[0] = -2.279097, states[40]= 0.004239
Saving checkpoint... 
Iteration: 1654000883, states[0] = -34.586910, states[40]= 0.000271
Saving checkpoint... 
Iteration: 1667721362, states[0] = 20.163048, states[40]= 0.008636
Saving checkpoint... 
Iteration: 1681302380, states[0] = -36.152963, states[40]= 0.000222
Saving checkpoint... 
Iteration: 1694936539, states[0] = -95.141454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1708525887, states[0] = 18.715001, states[40]= 0.007019
Saving checkpoint... 
Iteration: 1722116886, states[0] = -51.920666, states[40]= 0.000021
Saving checkpoint... 
Iteration: 1735775132, states[0] = -95.173169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1749426966, states[0] = -64.744700, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1763018912, states[0] = -95.121780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1776753639, states[0] = -94.986062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1790352497, states[0] = -95.156187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1803990148, states[0] = -95.019584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1817518360, states[0] = 20.778405, states[40]= 0.009516
Saving checkpoint... 
Iteration: 1831145390, states[0] = -60.712282, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1844707643, states[0] = -94.856338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1858373469, states[0] = -94.979266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1872022651, states[0] = 20.223210, states[40]= 0.006906
Saving checkpoint... 
Iteration: 1885593101, states[0] = -10.452648, states[40]= 0.002148
Saving checkpoint... 
Iteration: 1894850928, states[0] = -94.967472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1908937094, states[0] = -94.988922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1918908591, states[0] = -94.983065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1933315870, states[0] = -94.950364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1942948577, states[0] = -94.989855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1957080189, states[0] = -1.297910, states[40]= 0.003882
Saving checkpoint... 
Iteration: 1967637531, states[0] = -50.432792, states[40]= 0.000025
Saving checkpoint... 
Iteration: 1981897330, states[0] = -94.979545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1989521854, states[0] = 20.446294, states[40]= 0.007263
Saving checkpoint... 
Iteration: 1999393049, states[0] = -94.978407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2014714317, states[0] = -94.856575, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2029784167, states[0] = -94.930021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2045045324, states[0] = 13.461452, states[40]= 0.004682
Saving checkpoint... 
Iteration: 2060450819, states[0] = -94.989615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2076372874, states[0] = -94.972657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2091666173, states[0] = -92.416284, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.871353
 - CaMKt in component CaMK (millimolar): 0.007056
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.737240
 - nass in component intracellular_ions (millimolar): 6.737296
 - ki in component intracellular_ions (millimolar): 145.240615
 - kss in component intracellular_ions (millimolar): 145.240600
 - cansr in component intracellular_ions (millimolar): 1.304966
 - cajsr in component intracellular_ions (millimolar): 1.266348
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003630
 - hf in component INa (dimensionless): 0.879471
 - hs in component INa (dimensionless): 0.879467
 - j in component INa (dimensionless): 0.879443
 - hsp in component INa (dimensionless): 0.724837
 - jp in component INa (dimensionless): 0.879427
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.708275
 - hLp in component INaL (dimensionless): 0.448737
 - a in component Ito (dimensionless): 0.000625
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.615838
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.690332
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934244
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999879
 - jca in component ICaL (dimensionless): 0.999975
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001550
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.305972
 - xs1 in component IKs (dimensionless): 0.247361
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997345
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
06:00:54 (13760): called boinc_finish(0)

</stderr_txt>
]]>


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