𝕏

Task 54819907

Name HuVeMOp_20240626113555201639_ORdGradInc_k_24-Pueyo_APDR-conf_569_1
Workunit 26029204
Created 26 Jun 2024, 9:40:04 UTC
Sent 26 Jun 2024, 11:44:15 UTC
Report deadline 29 Jun 2024, 21:20:15 UTC
Received 28 Jun 2024, 10:51:34 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241457
Run time 2 hours 51 min 54 sec
CPU time 2 hours 50 min 44 sec
Validate state Valid
Credit 61.14
Device peak FLOPS 3.42 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.78 MB
Peak swap size 6.14 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626113555201639_ORdGradInc_k_24-Pueyo_APDR-conf_569.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626113555201639_ORdGradInc_k_24-Pueyo_APDR-conf_569_1_r925469209_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626113555201639_ORdGradInc_k_24-Pueyo_APDR-conf_569_1_r925469209_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 125.203024
     * GNaL_b in INaL: 0.009254
     * Gto_b in Ito: 0.067204
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032680
     * GKs_b in IKs: 0.001794
     * GK1_b in IK1: 0.170947
     * Gncx_b in INaCa_i: 0.000946
     * Pnak_b in INaK: 67.920486
     * GKb_b in IKb: 0.003908
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.054022
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 5143737, states[0] = -69.997592, states[40]= 0.000001
Saving checkpoint... 
Iteration: 18792727, states[0] = -95.189084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 32551242, states[0] = 12.313429, states[40]= 0.005330
Saving checkpoint... 
Iteration: 46358362, states[0] = -95.189526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 60073441, states[0] = 2.911615, states[40]= 0.004695
Saving checkpoint... 
Iteration: 73732994, states[0] = -95.085379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 87403725, states[0] = -95.187186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 101140069, states[0] = -56.164688, states[40]= 0.000011
Saving checkpoint... 
Iteration: 113308568, states[0] = -95.146460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 126934268, states[0] = -95.188970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 140768546, states[0] = -95.115143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 154483985, states[0] = -95.194966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 168127286, states[0] = -41.093161, states[40]= 0.000116
Saving checkpoint... 
Iteration: 181820866, states[0] = -95.150628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 195490583, states[0] = -95.195003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 209136119, states[0] = -50.928864, states[40]= 0.000026
Saving checkpoint... 
Iteration: 222930539, states[0] = -95.186242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 236744627, states[0] = -95.089363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 250504750, states[0] = 34.152429, states[40]= 0.122814
Saving checkpoint... 
Iteration: 264312005, states[0] = -95.145277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 278109118, states[0] = -23.594058, states[40]= 0.000804
Saving checkpoint... 
Iteration: 291149328, states[0] = -68.020318, states[40]= 0.000001
Saving checkpoint... 
Iteration: 304869921, states[0] = -95.170838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 318644328, states[0] = -61.087734, states[40]= 0.000005
Saving checkpoint... 
Iteration: 332382864, states[0] = -95.174840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346073390, states[0] = 3.399493, states[40]= 0.004718
Saving checkpoint... 
Iteration: 359893337, states[0] = -95.177737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 373494177, states[0] = -95.195006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 387301079, states[0] = -95.138493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 400624888, states[0] = -38.579776, states[40]= 0.000166
Saving checkpoint... 
Iteration: 412622568, states[0] = -36.274134, states[40]= 0.000229
Saving checkpoint... 
Iteration: 426332906, states[0] = -95.156104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 440050174, states[0] = 13.429616, states[40]= 0.005340
Saving checkpoint... 
Iteration: 453787322, states[0] = -95.128924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 467473988, states[0] = -95.192675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 481132420, states[0] = -46.619738, states[40]= 0.000051
Saving checkpoint... 
Iteration: 494851260, states[0] = -95.163999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 508478258, states[0] = -95.193178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 522207959, states[0] = -95.038816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 535933456, states[0] = -95.186507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 549693260, states[0] = -95.014114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 563573797, states[0] = 3.197242, states[40]= 0.004699
Saving checkpoint... 
Iteration: 577284238, states[0] = -95.126542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 590929485, states[0] = -95.185747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 600441753, states[0] = -95.187930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 614100189, states[0] = -15.372366, states[40]= 0.001428
Saving checkpoint... 
Iteration: 627835389, states[0] = -95.157171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641471472, states[0] = -95.192281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 655287739, states[0] = -95.129144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 669007719, states[0] = 28.564280, states[40]= 0.085879
Saving checkpoint... 
Iteration: 682770675, states[0] = -95.115347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 696470189, states[0] = -95.192092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 710210324, states[0] = -95.042478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 723671800, states[0] = -94.728217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 737270931, states[0] = -95.115548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 751049063, states[0] = 13.866696, states[40]= 0.005372
Saving checkpoint... 
Iteration: 764886426, states[0] = -95.175665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 778609579, states[0] = -24.017705, states[40]= 0.000784
Saving checkpoint... 
Iteration: 792441130, states[0] = -95.187740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 806111397, states[0] = -25.699320, states[40]= 0.000706
Saving checkpoint... 
Iteration: 815657938, states[0] = -82.955168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 829239412, states[0] = -95.082862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 843003385, states[0] = 39.925297, states[40]= 0.108502
Saving checkpoint... 
Iteration: 856840445, states[0] = -95.159340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 870583137, states[0] = -1.968302, states[40]= 0.004014
Saving checkpoint... 
Iteration: 884207066, states[0] = -95.037223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 897894799, states[0] = -95.177880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 911663929, states[0] = -91.879171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 925380817, states[0] = -95.173967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 939071375, states[0] = 4.381207, states[40]= 0.004805
Saving checkpoint... 
Iteration: 952190328, states[0] = -95.008561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 965818901, states[0] = -95.148786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 979526279, states[0] = 21.999396, states[40]= 0.007944
Saving checkpoint... 
Iteration: 993286222, states[0] = -95.127863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1006958646, states[0] = -95.190382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1019898682, states[0] = -95.178821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1033193013, states[0] = -95.013457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1046978903, states[0] = -95.193016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1056444043, states[0] = -95.188110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1070153420, states[0] = -74.579700, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1083882758, states[0] = -95.174470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1097567567, states[0] = 6.155139, states[40]= 0.004936
Saving checkpoint... 
Iteration: 1111338423, states[0] = -95.158332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1125132962, states[0] = -47.234992, states[40]= 0.000046
Saving checkpoint... 
Iteration: 1138646376, states[0] = -63.821132, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1152391188, states[0] = -95.176808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1166135236, states[0] = -49.866769, states[40]= 0.000031
Saving checkpoint... 
Iteration: 1179900086, states[0] = -95.179101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1193633129, states[0] = -47.425577, states[40]= 0.000045
Saving checkpoint... 
Iteration: 1207335489, states[0] = -95.156960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1221066539, states[0] = 6.618562, states[40]= 0.004966
Saving checkpoint... 
Iteration: 1234860788, states[0] = -95.167263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1248518946, states[0] = 24.038419, states[40]= 0.012846
Saving checkpoint... 
Iteration: 1261855722, states[0] = -95.165382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1275438184, states[0] = -95.187020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1289181733, states[0] = -94.985165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1302965605, states[0] = -95.191219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1316568591, states[0] = 5.687444, states[40]= 0.004904
Saving checkpoint... 
Iteration: 1330388397, states[0] = -95.175966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1344076247, states[0] = 1.945670, states[40]= 0.004569
Saving checkpoint... 
Iteration: 1357860774, states[0] = -95.167204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1371589633, states[0] = -6.417433, states[40]= 0.003125
Saving checkpoint... 
Iteration: 1385185071, states[0] = -94.996859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1398872277, states[0] = -95.171109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1412605482, states[0] = -20.237500, states[40]= 0.000976
Saving checkpoint... 
Iteration: 1426288030, states[0] = -95.129016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1440038287, states[0] = 17.962023, states[40]= 0.005929
Saving checkpoint... 
Iteration: 1453839778, states[0] = -95.158782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1467519707, states[0] = 23.840538, states[40]= 0.011937
Saving checkpoint... 
Iteration: 1481287862, states[0] = -95.128868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1495041176, states[0] = 16.894492, states[40]= 0.005719
Saving checkpoint... 
Iteration: 1508795213, states[0] = -25.085727, states[40]= 0.000717
Saving checkpoint... 
Iteration: 1519137483, states[0] = -95.376912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1532546097, states[0] = -94.227005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1546138742, states[0] = -95.398319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1559885317, states[0] = -95.328398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1573580517, states[0] = -12.509966, states[40]= 0.002114
Saving checkpoint... 
Iteration: 1587298713, states[0] = -95.455895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1600882188, states[0] = -14.434924, states[40]= 0.001760
Saving checkpoint... 
Iteration: 1614574678, states[0] = -95.443527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1628258351, states[0] = -95.272667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1641920411, states[0] = 22.883973, states[40]= 0.012598
Saving checkpoint... 
Iteration: 1655612069, states[0] = -95.381755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1669212394, states[0] = 26.089318, states[40]= 0.035025
Saving checkpoint... 
Iteration: 1682749655, states[0] = 9.282970, states[40]= 0.005953
Saving checkpoint... 
Iteration: 1696377275, states[0] = -95.323184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1710074739, states[0] = -7.272882, states[40]= 0.003326
Saving checkpoint... 
Iteration: 1723753087, states[0] = -95.428162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1737432517, states[0] = -78.085282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1751143091, states[0] = 12.672367, states[40]= 0.006362
Saving checkpoint... 
Iteration: 1764578345, states[0] = -95.447766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1777820736, states[0] = 22.749121, states[40]= 0.012282
Saving checkpoint... 
Iteration: 1791576940, states[0] = -95.446804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1805270229, states[0] = -95.163331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1818890115, states[0] = -95.212803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1832534270, states[0] = 19.005368, states[40]= 0.006340
Saving checkpoint... 
Iteration: 1846276135, states[0] = -95.136406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1859958696, states[0] = -95.201243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1873618707, states[0] = -33.114434, states[40]= 0.000345
Saving checkpoint... 
Iteration: 1887051218, states[0] = 12.911338, states[40]= 0.005316
Saving checkpoint... 
Iteration: 1900696234, states[0] = -95.022159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1914249695, states[0] = -95.096529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1927897222, states[0] = -95.179585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1941601487, states[0] = -16.630319, states[40]= 0.001278
Saving checkpoint... 
Iteration: 1955239692, states[0] = -95.083388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1968897918, states[0] = -95.178652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1982559140, states[0] = 9.798233, states[40]= 0.005141
Saving checkpoint... 
Iteration: 1996182130, states[0] = -94.986867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2005853507, states[0] = -95.164335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2019248157, states[0] = -95.092537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2030595840, states[0] = -11.488652, states[40]= 0.002053
Saving checkpoint... 
Iteration: 2043965472, states[0] = -95.190891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2055358431, states[0] = -95.166043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2069391491, states[0] = -95.176472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2079173803, states[0] = -94.852821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2088862361, states[0] = -95.167424, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -95.070670
 - CaMKt in component CaMK (millimolar): 0.006565
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.612619
 - nass in component intracellular_ions (millimolar): 6.612678
 - ki in component intracellular_ions (millimolar): 145.372271
 - kss in component intracellular_ions (millimolar): 145.372250
 - cansr in component intracellular_ions (millimolar): 1.287540
 - cajsr in component intracellular_ions (millimolar): 1.249671
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003557
 - hf in component INa (dimensionless): 0.882899
 - hs in component INa (dimensionless): 0.882895
 - j in component INa (dimensionless): 0.882872
 - hsp in component INa (dimensionless): 0.731320
 - jp in component INa (dimensionless): 0.882856
 - mL in component INaL (dimensionless): 0.000048
 - hL in component INaL (dimensionless): 0.713900
 - hLp in component INaL (dimensionless): 0.455678
 - a in component Ito (dimensionless): 0.000616
 - iF in component Ito (dimensionless): 0.999873
 - iS in component Ito (dimensionless): 0.618438
 - ap in component Ito (dimensionless): 0.000314
 - iFp in component Ito (dimensionless): 0.999873
 - iSp in component Ito (dimensionless): 0.692079
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.927067
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999857
 - jca in component ICaL (dimensionless): 0.999975
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001531
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.354603
 - xs1 in component IKs (dimensionless): 0.253778
 - xs2 in component IKs (dimensionless): 0.000086
 - xk1 in component IK1 (dimensionless): 0.997292
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
05:51:22 (9456): called boinc_finish(0)

</stderr_txt>
]]>


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