𝕏

Task 54818702

Name HuVeMOp_20240626113555201639_ORdGradInc_k_24-Pueyo_APDR-conf_54_0
Workunit 26028603
Created 26 Jun 2024, 9:39:18 UTC
Sent 26 Jun 2024, 11:37:11 UTC
Report deadline 29 Jun 2024, 21:13:11 UTC
Received 27 Jun 2024, 13:32:16 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 238614
Run time 2 hours 29 min 43 sec
CPU time 2 hours 29 min 18 sec
Validate state Valid
Credit 57.24
Device peak FLOPS 3.71 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.95 MB
Peak swap size 3.82 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.14.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626113555201639_ORdGradInc_k_24-Pueyo_APDR-conf_54.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626113555201639_ORdGradInc_k_24-Pueyo_APDR-conf_54_0_r830500616_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626113555201639_ORdGradInc_k_24-Pueyo_APDR-conf_54_0_r830500616_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 121.485168
     * GNaL_b in INaL: 0.007962
     * Gto_b in Ito: 0.067500
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.033977
     * GKs_b in IKs: 0.001834
     * GK1_b in IK1: 0.176011
     * Gncx_b in INaCa_i: 0.000958
     * Pnak_b in INaK: 64.094213
     * GKb_b in IKb: 0.004046
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036418
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11621709, states[0] = -46.060831, states[40]= 0.000050
Saving checkpoint... 
Iteration: 22934943, states[0] = -95.098997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35122119, states[0] = -45.199418, states[40]= 0.000060
Saving checkpoint... 
Iteration: 48929574, states[0] = -95.085076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 66254398, states[0] = -94.995018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 78405430, states[0] = -95.074209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 90448392, states[0] = -95.081444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 101655666, states[0] = -91.826475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 114057456, states[0] = 8.196493, states[40]= 0.005176
Saving checkpoint... 
Iteration: 125300315, states[0] = -95.028146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 136314951, states[0] = -95.036730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 151921230, states[0] = -95.074046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 163744194, states[0] = -94.978190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 176570180, states[0] = 2.033001, states[40]= 0.004690
Saving checkpoint... 
Iteration: 188601085, states[0] = -22.828852, states[40]= 0.000821
Saving checkpoint... 
Iteration: 199629261, states[0] = -52.198475, states[40]= 0.000020
Saving checkpoint... 
Iteration: 210807768, states[0] = -95.031803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 222031680, states[0] = 18.775135, states[40]= 0.006685
Saving checkpoint... 
Iteration: 233498194, states[0] = -95.084878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 244652036, states[0] = -86.826363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 257561211, states[0] = 6.514701, states[40]= 0.005071
Saving checkpoint... 
Iteration: 272688932, states[0] = -94.894683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 283894068, states[0] = -95.067125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 295242781, states[0] = -94.976134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 306409482, states[0] = -95.070918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 318602289, states[0] = -23.979483, states[40]= 0.000762
Saving checkpoint... 
Iteration: 330082823, states[0] = -6.084478, states[40]= 0.003284
Saving checkpoint... 
Iteration: 341613194, states[0] = -34.625064, states[40]= 0.000273
Saving checkpoint... 
Iteration: 352772521, states[0] = -95.006057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 364104879, states[0] = -26.483434, states[40]= 0.000640
Saving checkpoint... 
Iteration: 375986675, states[0] = -95.083541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 387453567, states[0] = -95.079191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 398652356, states[0] = -87.357770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 410010978, states[0] = 25.431807, states[40]= 0.044304
Saving checkpoint... 
Iteration: 422875908, states[0] = -95.061792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 434226939, states[0] = -94.956015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 447450165, states[0] = -95.078633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 459045116, states[0] = 13.523581, states[40]= 0.005547
Saving checkpoint... 
Iteration: 470052384, states[0] = 10.459977, states[40]= 0.005306
Saving checkpoint... 
Iteration: 480878470, states[0] = -95.062559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 492316475, states[0] = -95.036623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 503673448, states[0] = -94.857634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 514772372, states[0] = -95.005846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 527666674, states[0] = -94.769208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 540493190, states[0] = -95.084164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 553785861, states[0] = -95.016717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 565180936, states[0] = -94.879132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 576731275, states[0] = -94.961745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 590118043, states[0] = -39.559414, states[40]= 0.000139
Saving checkpoint... 
Iteration: 601968256, states[0] = -95.081179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 612999360, states[0] = -95.084757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 626362412, states[0] = -95.057164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 638362811, states[0] = -95.057300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 649998682, states[0] = -95.084672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 661175884, states[0] = -94.866736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 672404753, states[0] = -95.069619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 683547638, states[0] = 12.474992, states[40]= 0.005449
Saving checkpoint... 
Iteration: 694907676, states[0] = -95.070300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 706549570, states[0] = 11.661672, states[40]= 0.005386
Saving checkpoint... 
Iteration: 717628255, states[0] = -50.983044, states[40]= 0.000025
Saving checkpoint... 
Iteration: 728658428, states[0] = -93.481675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 739865132, states[0] = -95.058067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 751544026, states[0] = 13.972380, states[40]= 0.005596
Saving checkpoint... 
Iteration: 764612050, states[0] = -33.488498, states[40]= 0.000315
Saving checkpoint... 
Iteration: 776628602, states[0] = -51.396549, states[40]= 0.000023
Saving checkpoint... 
Iteration: 788617914, states[0] = -39.424780, states[40]= 0.000142
Saving checkpoint... 
Iteration: 800175447, states[0] = -94.865277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 811335658, states[0] = -95.046188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 823004891, states[0] = 32.844243, states[40]= 0.130688
Saving checkpoint... 
Iteration: 834683425, states[0] = -94.883991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 847064554, states[0] = 4.921186, states[40]= 0.004959
Saving checkpoint... 
Iteration: 858333277, states[0] = -95.045053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 871684780, states[0] = -94.886587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 883414211, states[0] = -95.071689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 896937465, states[0] = -95.076284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 912158613, states[0] = -93.560489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 923630642, states[0] = -53.855428, states[40]= 0.000015
Saving checkpoint... 
Iteration: 935803101, states[0] = -95.028456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 947341564, states[0] = -95.048768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 958273923, states[0] = -95.006954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 971442834, states[0] = -95.077176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 982846883, states[0] = -95.051009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 993689200, states[0] = -94.894799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1004735340, states[0] = -94.966749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1016149601, states[0] = -82.331846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1027556735, states[0] = 8.554673, states[40]= 0.005194
Saving checkpoint... 
Iteration: 1040052323, states[0] = 10.486346, states[40]= 0.005308
Saving checkpoint... 
Iteration: 1052536673, states[0] = 16.907564, states[40]= 0.006089
Saving checkpoint... 
Iteration: 1063738699, states[0] = -94.970875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1076653629, states[0] = -89.298137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1088824961, states[0] = -95.040851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1100771466, states[0] = -95.004767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1113239776, states[0] = -94.972154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1124337568, states[0] = -95.046904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1135820131, states[0] = -95.038297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1148368207, states[0] = -95.058918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1160489252, states[0] = -95.083434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1171846574, states[0] = -95.050787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1182864862, states[0] = -95.057752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1193997388, states[0] = -95.084271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1207091190, states[0] = -13.323926, states[40]= 0.001777
Saving checkpoint... 
Iteration: 1225193462, states[0] = -94.902431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1238267300, states[0] = -95.000988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1251247828, states[0] = -94.981391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1264053080, states[0] = 10.159465, states[40]= 0.005287
Saving checkpoint... 
Iteration: 1277026046, states[0] = 20.717806, states[40]= 0.007917
Saving checkpoint... 
Iteration: 1289096339, states[0] = -18.235045, states[40]= 0.001136
Saving checkpoint... 
Iteration: 1302566235, states[0] = 4.090201, states[40]= 0.004891
Saving checkpoint... 
Iteration: 1316077264, states[0] = -2.135720, states[40]= 0.004087
Saving checkpoint... 
Iteration: 1331078553, states[0] = -2.989769, states[40]= 0.003930
Saving checkpoint... 
Iteration: 1342494124, states[0] = -95.083863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1354597788, states[0] = -19.633112, states[40]= 0.001019
Saving checkpoint... 
Iteration: 1368873673, states[0] = -95.060610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1380335112, states[0] = -95.045651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1391649511, states[0] = -82.157978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1403340597, states[0] = -95.048117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1417250672, states[0] = -94.984417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1433842094, states[0] = -95.048755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1445970539, states[0] = -95.081059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1458642694, states[0] = -70.023574, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1473788263, states[0] = -95.018045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1485404928, states[0] = -95.069255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1499128395, states[0] = -51.149236, states[40]= 0.000024
Saving checkpoint... 
Iteration: 1511240909, states[0] = -94.044026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1523163527, states[0] = -0.633666, states[40]= 0.004812
Saving checkpoint... 
Iteration: 1535104979, states[0] = 33.817436, states[40]= 0.108454
Saving checkpoint... 
Iteration: 1546701932, states[0] = -95.232618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1558292244, states[0] = -30.545162, states[40]= 0.000438
Saving checkpoint... 
Iteration: 1570115973, states[0] = -95.260813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1581818103, states[0] = -95.265876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1593611119, states[0] = 25.831770, states[40]= 0.043752
Saving checkpoint... 
Iteration: 1611116089, states[0] = -60.761565, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1623175179, states[0] = -95.198238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1637556829, states[0] = -95.156532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1649195850, states[0] = -35.185147, states[40]= 0.000255
Saving checkpoint... 
Iteration: 1661344894, states[0] = -95.300723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1672637163, states[0] = -93.810070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1683813975, states[0] = -95.265119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1694935488, states[0] = -95.291330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1705873721, states[0] = -10.888071, states[40]= 0.002506
Saving checkpoint... 
Iteration: 1717676474, states[0] = -95.202102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1728512728, states[0] = -95.263522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1742408712, states[0] = 27.507129, states[40]= 0.069108
Saving checkpoint... 
Iteration: 1755117713, states[0] = -63.311491, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1767204311, states[0] = -95.251318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1779540850, states[0] = -95.297012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1791269273, states[0] = -95.321853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1802502927, states[0] = 41.424523, states[40]= 0.135795
Saving checkpoint... 
Iteration: 1813046719, states[0] = 12.047413, states[40]= 0.005521
Saving checkpoint... 
Iteration: 1826795345, states[0] = -95.050574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1839851503, states[0] = -95.071563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1851834233, states[0] = -95.058526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1865202585, states[0] = -94.927348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1881462818, states[0] = -95.085483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1895426139, states[0] = -95.077452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1909043152, states[0] = 14.281796, states[40]= 0.005640
Saving checkpoint... 
Iteration: 1919958856, states[0] = -95.081059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1931818597, states[0] = -95.038377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1949935935, states[0] = -95.076241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1967637488, states[0] = -62.589797, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1985805828, states[0] = -95.029882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2003859979, states[0] = -95.055725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2016686671, states[0] = -94.889665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2027920064, states[0] = -95.072414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2038860354, states[0] = -95.055737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2051823999, states[0] = -95.039876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2062963548, states[0] = -95.079799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2075191122, states[0] = -94.897753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2088694419, states[0] = -94.903683, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.959924
 - CaMKt in component CaMK (millimolar): 0.006639
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.801710
 - nass in component intracellular_ions (millimolar): 6.801770
 - ki in component intracellular_ions (millimolar): 145.179619
 - kss in component intracellular_ions (millimolar): 145.179599
 - cansr in component intracellular_ions (millimolar): 1.301391
 - cajsr in component intracellular_ions (millimolar): 1.264328
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003597
 - hf in component INa (dimensionless): 0.881005
 - hs in component INa (dimensionless): 0.881001
 - j in component INa (dimensionless): 0.880977
 - hsp in component INa (dimensionless): 0.727729
 - jp in component INa (dimensionless): 0.880960
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.712906
 - hLp in component INaL (dimensionless): 0.458218
 - a in component Ito (dimensionless): 0.000621
 - iF in component Ito (dimensionless): 0.999871
 - iS in component Ito (dimensionless): 0.626249
 - ap in component Ito (dimensionless): 0.000316
 - iFp in component Ito (dimensionless): 0.999871
 - iSp in component Ito (dimensionless): 0.701633
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934704
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999885
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001582
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.342801
 - xs1 in component IKs (dimensionless): 0.237748
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997322
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
15:10:15 (80870): called boinc_finish(0)

</stderr_txt>
]]>


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