𝕏

Task 54817901

Name HuVeMOp_20240626113555201639_ORdGradInc_k_24-Pueyo_APDR-conf_544_1
Workunit 26028202
Created 26 Jun 2024, 9:38:47 UTC
Sent 26 Jun 2024, 11:31:45 UTC
Report deadline 29 Jun 2024, 21:07:45 UTC
Received 28 Jun 2024, 15:20:31 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 237135
Run time 3 hours 4 min 46 sec
CPU time 1 hours 44 min 42 sec
Validate state Valid
Credit 64.53
Device peak FLOPS 4.35 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 8.31 MB
Peak swap size 4.38 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626113555201639_ORdGradInc_k_24-Pueyo_APDR-conf_544.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626113555201639_ORdGradInc_k_24-Pueyo_APDR-conf_544_1_r661178579_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626113555201639_ORdGradInc_k_24-Pueyo_APDR-conf_544_1_r661178579_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 104.113255
     * GNaL_b in INaL: 0.006563
     * Gto_b in Ito: 0.070057
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032185
     * GKs_b in IKs: 0.001857
     * GK1_b in IK1: 0.177453
     * Gncx_b in INaCa_i: 0.000950
     * Pnak_b in INaK: 67.169061
     * GKb_b in IKb: 0.003824
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.047303
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 10988490, states[0] = -95.214373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 21588253, states[0] = -11.751797, states[40]= 0.002049
Saving checkpoint... 
Iteration: 32825454, states[0] = -95.137744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 44938140, states[0] = -95.162894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59725757, states[0] = -95.033827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 73739805, states[0] = -95.047325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 86661607, states[0] = -94.045139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 101318219, states[0] = -95.107260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 115357282, states[0] = -95.123577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 129051676, states[0] = 11.168373, states[40]= 0.005204
Saving checkpoint... 
Iteration: 142723428, states[0] = -95.017989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 155919034, states[0] = -95.139146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 169087750, states[0] = -8.896503, states[40]= 0.002620
Saving checkpoint... 
Iteration: 185850767, states[0] = -95.118697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 198166884, states[0] = -94.745306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 210174918, states[0] = -94.922941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 216988695, states[0] = -95.149125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 225402887, states[0] = -95.134742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 233521427, states[0] = 22.127398, states[40]= 0.009494
Saving checkpoint... 
Iteration: 241723809, states[0] = -95.017289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 251265770, states[0] = -95.065651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 265817261, states[0] = -95.102636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 280851814, states[0] = -95.118721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 291205277, states[0] = -94.988661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 305350131, states[0] = -95.118030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 318848576, states[0] = -95.117393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 332660579, states[0] = -93.436570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346241752, states[0] = -95.040393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 359504886, states[0] = 31.508754, states[40]= 0.136723
Saving checkpoint... 
Iteration: 370225131, states[0] = -95.019001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 383170032, states[0] = -94.865379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 397238696, states[0] = -95.036694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 411035187, states[0] = 17.704178, states[40]= 0.005973
Saving checkpoint... 
Iteration: 424067410, states[0] = 4.172457, states[40]= 0.004811
Saving checkpoint... 
Iteration: 436742340, states[0] = -95.041032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 449170260, states[0] = -94.870235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 460407070, states[0] = -95.135493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 470051257, states[0] = 11.382269, states[40]= 0.005212
Saving checkpoint... 
Iteration: 478848837, states[0] = -95.117404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 489313801, states[0] = -95.100543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 499803944, states[0] = -95.094653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 509514787, states[0] = 23.805714, states[40]= 0.020291
Saving checkpoint... 
Iteration: 520437729, states[0] = -95.141687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 534868804, states[0] = -95.124717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 547280505, states[0] = -95.078060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 560381179, states[0] = -95.128604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 572764967, states[0] = -95.064674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 585322325, states[0] = -95.105137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 597732497, states[0] = -95.028787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 607413155, states[0] = -95.136793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 616348837, states[0] = -95.117328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 624435883, states[0] = -95.141303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 636017733, states[0] = 23.080867, states[40]= 0.013352
Saving checkpoint... 
Iteration: 648053347, states[0] = 10.509558, states[40]= 0.005168
Saving checkpoint... 
Iteration: 660623990, states[0] = -44.003766, states[40]= 0.000072
Saving checkpoint... 
Iteration: 673312074, states[0] = -95.099453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685831644, states[0] = -95.109736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 695967925, states[0] = -95.146214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 710338184, states[0] = -95.112745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 726378819, states[0] = -95.127804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 740370654, states[0] = -95.125217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 755106766, states[0] = -26.751993, states[40]= 0.000627
Saving checkpoint... 
Iteration: 768622892, states[0] = -42.829648, states[40]= 0.000086
Saving checkpoint... 
Iteration: 781637218, states[0] = -59.259282, states[40]= 0.000006
Saving checkpoint... 
Iteration: 794241417, states[0] = -95.039747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 809926341, states[0] = -95.139420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 824629606, states[0] = -50.237934, states[40]= 0.000027
Saving checkpoint... 
Iteration: 839779585, states[0] = -95.077166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 854048103, states[0] = 12.677924, states[40]= 0.005289
Saving checkpoint... 
Iteration: 867590701, states[0] = -11.453311, states[40]= 0.002091
Saving checkpoint... 
Iteration: 881560032, states[0] = 7.619972, states[40]= 0.005031
Saving checkpoint... 
Iteration: 893689496, states[0] = -94.960448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 905348857, states[0] = -95.117178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 916304870, states[0] = -95.095003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 926249166, states[0] = -95.048507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 937652675, states[0] = -83.562792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 948032838, states[0] = 18.547764, states[40]= 0.006222
Saving checkpoint... 
Iteration: 962303868, states[0] = -95.094352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 974376833, states[0] = -95.127059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 988374680, states[0] = -95.126378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1002163218, states[0] = -94.298051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1015744732, states[0] = -95.043490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1028978967, states[0] = -95.147423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1042676985, states[0] = -94.931681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1055879684, states[0] = -95.127886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1067441039, states[0] = -95.141961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1080502233, states[0] = 44.494266, states[40]= 0.094130
Saving checkpoint... 
Iteration: 1096371122, states[0] = -95.125176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1110370895, states[0] = -95.125094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1124101219, states[0] = -21.413852, states[40]= 0.000893
Saving checkpoint... 
Iteration: 1137350744, states[0] = -95.117807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1151330738, states[0] = -95.109047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167007393, states[0] = 27.137593, states[40]= 0.092340
Saving checkpoint... 
Iteration: 1175490875, states[0] = -95.148689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1185056436, states[0] = 9.195247, states[40]= 0.005107
Saving checkpoint... 
Iteration: 1194187548, states[0] = -94.956612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1205027196, states[0] = 20.437616, states[40]= 0.007175
Saving checkpoint... 
Iteration: 1217693628, states[0] = -94.967861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232687066, states[0] = -94.955670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1247793150, states[0] = -95.087099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1259462725, states[0] = -95.145200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1272213915, states[0] = -95.001996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1285799994, states[0] = -95.091698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1301837081, states[0] = -95.111925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1317705966, states[0] = -94.989223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1333473867, states[0] = -95.146633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1345942898, states[0] = -95.142122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1358526645, states[0] = 20.610352, states[40]= 0.007312
Saving checkpoint... 
Iteration: 1367752502, states[0] = -95.051857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1378748746, states[0] = -95.047798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1392887460, states[0] = -95.129962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1404721714, states[0] = -95.013585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1418024501, states[0] = 21.260239, states[40]= 0.007971
Saving checkpoint... 
Iteration: 1432214759, states[0] = -95.003211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1444980990, states[0] = -95.147436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1455751329, states[0] = -95.050560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1465981977, states[0] = -95.147539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1479729319, states[0] = -95.024114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493685336, states[0] = -94.952167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1506517609, states[0] = -95.287894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1520679694, states[0] = -95.358111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1533178699, states[0] = -95.244754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1547020870, states[0] = -95.320210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1556917721, states[0] = -95.319957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1567079935, states[0] = -95.261384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1579409401, states[0] = -95.313891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1594013778, states[0] = -55.111575, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1603510214, states[0] = 25.818487, states[40]= 0.050238
Saving checkpoint... 
Iteration: 1611915977, states[0] = 23.424005, states[40]= 0.018430
Saving checkpoint... 
Iteration: 1622180794, states[0] = -17.040754, states[40]= 0.001382
Saving checkpoint... 
Iteration: 1632367646, states[0] = -3.942408, states[40]= 0.004136
Saving checkpoint... 
Iteration: 1641178995, states[0] = -95.266489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1649070697, states[0] = -95.382429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1656249349, states[0] = -95.364982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1667461224, states[0] = 0.848752, states[40]= 0.005030
Saving checkpoint... 
Iteration: 1681118934, states[0] = -95.331868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1693944549, states[0] = -94.998031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1707216060, states[0] = -95.328191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1719600233, states[0] = -66.799509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1732603077, states[0] = -41.991750, states[40]= 0.000100
Saving checkpoint... 
Iteration: 1745075105, states[0] = -95.386051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1758700657, states[0] = -39.176562, states[40]= 0.000150
Saving checkpoint... 
Iteration: 1771437365, states[0] = -95.353533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1785387577, states[0] = -24.607246, states[40]= 0.000741
Saving checkpoint... 
Iteration: 1796742324, states[0] = 11.824702, states[40]= 0.006235
Saving checkpoint... 
Iteration: 1808528082, states[0] = 19.553207, states[40]= 0.006821
Saving checkpoint... 
Iteration: 1819694545, states[0] = -95.000117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1828280846, states[0] = -95.103061, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1833925079, states[0] = -95.160263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1840048792, states[0] = 12.018894, states[40]= 0.005280
Saving checkpoint... 
Iteration: 1847140881, states[0] = -65.757957, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1850436718, states[0] = -95.154244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1855414103, states[0] = -95.147976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1858379525, states[0] = -95.138104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1862876972, states[0] = -95.136014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1870325851, states[0] = -95.113842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1880057190, states[0] = 8.730717, states[40]= 0.005093
Saving checkpoint... 
Iteration: 1891512419, states[0] = 24.404090, states[40]= 0.031370
Saving checkpoint... 
Iteration: 1907506830, states[0] = 27.764249, states[40]= 0.103322
Saving checkpoint... 
Iteration: 1920515899, states[0] = 23.512251, states[40]= 0.017023
Saving checkpoint... 
Iteration: 1932953830, states[0] = -95.144759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1945807658, states[0] = -95.096982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1952855867, states[0] = -95.120015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1967436307, states[0] = -95.141071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1985023826, states[0] = 21.453750, states[40]= 0.008233
Saving checkpoint... 
Iteration: 2001873117, states[0] = -95.125458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2020251076, states[0] = -95.050039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2035719248, states[0] = -95.009664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2053605176, states[0] = -25.221989, states[40]= 0.000701
Saving checkpoint... 
Iteration: 2070882905, states[0] = -95.128266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2085741265, states[0] = -95.038827, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -95.024958
 - CaMKt in component CaMK (millimolar): 0.006761
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.631317
 - nass in component intracellular_ions (millimolar): 6.631376
 - ki in component intracellular_ions (millimolar): 145.348879
 - kss in component intracellular_ions (millimolar): 145.348859
 - cansr in component intracellular_ions (millimolar): 1.304128
 - cajsr in component intracellular_ions (millimolar): 1.266617
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003574
 - hf in component INa (dimensionless): 0.882120
 - hs in component INa (dimensionless): 0.882117
 - j in component INa (dimensionless): 0.882093
 - hsp in component INa (dimensionless): 0.729841
 - jp in component INa (dimensionless): 0.882077
 - mL in component INaL (dimensionless): 0.000048
 - hL in component INaL (dimensionless): 0.714039
 - hLp in component INaL (dimensionless): 0.458374
 - a in component Ito (dimensionless): 0.000618
 - iF in component Ito (dimensionless): 0.999872
 - iS in component Ito (dimensionless): 0.624396
 - ap in component Ito (dimensionless): 0.000315
 - iFp in component Ito (dimensionless): 0.999872
 - iSp in component Ito (dimensionless): 0.699582
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.933603
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999882
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001590
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.337478
 - xs1 in component IKs (dimensionless): 0.241123
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997305
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
00:20:17 (34600): called boinc_finish(0)

</stderr_txt>
]]>


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