𝕏

Task 54817226

Name HuVeMOp_20240626113555201639_ORdGradInc_k_24-Pueyo_APDR-conf_235_0
Workunit 26027914
Created 26 Jun 2024, 9:38:15 UTC
Sent 26 Jun 2024, 11:26:54 UTC
Report deadline 29 Jun 2024, 21:02:54 UTC
Received 28 Jun 2024, 21:28:17 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 227060
Run time 2 hours 56 min 52 sec
CPU time 2 hours 29 min 40 sec
Validate state Valid
Credit 59.94
Device peak FLOPS 4.67 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 1.74 MB
Peak swap size 4.02 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.18.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626113555201639_ORdGradInc_k_24-Pueyo_APDR-conf_235.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626113555201639_ORdGradInc_k_24-Pueyo_APDR-conf_235_0_r1466448037_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626113555201639_ORdGradInc_k_24-Pueyo_APDR-conf_235_0_r1466448037_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 121.695054
     * GNaL_b in INaL: 0.009298
     * Gto_b in Ito: 0.078279
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032552
     * GKs_b in IKs: 0.001931
     * GK1_b in IK1: 0.174209
     * Gncx_b in INaCa_i: 0.000954
     * Pnak_b in INaK: 66.621094
     * GKb_b in IKb: 0.003785
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.048106
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12016258, states[0] = 23.157191, states[40]= 0.016499
Saving checkpoint... 
Iteration: 23657157, states[0] = -83.404620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 34493241, states[0] = -95.233968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 45453255, states[0] = -95.221129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 57381042, states[0] = -95.199104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 69024033, states[0] = 22.034415, states[40]= 0.007997
Saving checkpoint... 
Iteration: 80651089, states[0] = -68.158289, states[40]= 0.000002
Saving checkpoint... 
Iteration: 92652644, states[0] = -70.288539, states[40]= 0.000001
Saving checkpoint... 
Iteration: 104505009, states[0] = 30.967796, states[40]= 0.137870
Saving checkpoint... 
Iteration: 115772694, states[0] = -95.128340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 128212233, states[0] = -95.051943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 140684276, states[0] = -94.995241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 153128514, states[0] = -40.176785, states[40]= 0.000138
Saving checkpoint... 
Iteration: 166333939, states[0] = -95.168022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 178114005, states[0] = -26.358744, states[40]= 0.000693
Saving checkpoint... 
Iteration: 190248851, states[0] = -95.101615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 201741251, states[0] = -95.092353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 213461638, states[0] = -95.203983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 225774158, states[0] = -95.127323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 237127006, states[0] = -38.597002, states[40]= 0.000173
Saving checkpoint... 
Iteration: 248889087, states[0] = -95.188549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260079105, states[0] = 1.235738, states[40]= 0.004416
Saving checkpoint... 
Iteration: 271350843, states[0] = -95.175119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 283409368, states[0] = -95.193868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 295121752, states[0] = -33.507678, states[40]= 0.000342
Saving checkpoint... 
Iteration: 308479683, states[0] = -95.206256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 320909928, states[0] = -95.193970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 331985182, states[0] = -95.206908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 344246622, states[0] = -95.098637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 356556648, states[0] = 11.270601, states[40]= 0.005035
Saving checkpoint... 
Iteration: 368692714, states[0] = -95.015691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 380839870, states[0] = -95.170196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 393908110, states[0] = -95.193486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 406049247, states[0] = 14.086198, states[40]= 0.005145
Saving checkpoint... 
Iteration: 417329527, states[0] = -95.165117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 429139745, states[0] = -52.587282, states[40]= 0.000021
Saving checkpoint... 
Iteration: 442128836, states[0] = -40.438807, states[40]= 0.000133
Saving checkpoint... 
Iteration: 454131577, states[0] = -43.305700, states[40]= 0.000088
Saving checkpoint... 
Iteration: 467077252, states[0] = 2.207463, states[40]= 0.004522
Saving checkpoint... 
Iteration: 479060384, states[0] = 9.788415, states[40]= 0.004987
Saving checkpoint... 
Iteration: 491497542, states[0] = -95.208201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 503240630, states[0] = -95.091207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 515706768, states[0] = -95.040927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 527641572, states[0] = -54.791086, states[40]= 0.000015
Saving checkpoint... 
Iteration: 539647565, states[0] = -62.386001, states[40]= 0.000004
Saving checkpoint... 
Iteration: 552232937, states[0] = -95.081093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 564256678, states[0] = -95.109874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 576120161, states[0] = -32.011262, states[40]= 0.000410
Saving checkpoint... 
Iteration: 588335374, states[0] = -95.167946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599794426, states[0] = -95.143435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 611212543, states[0] = -95.050517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 622923310, states[0] = -95.196810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 635834798, states[0] = -95.167640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 647815373, states[0] = -95.157184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 660028386, states[0] = 21.036647, states[40]= 0.006756
Saving checkpoint... 
Iteration: 671227708, states[0] = -95.073728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 683609139, states[0] = -21.905342, states[40]= 0.000894
Saving checkpoint... 
Iteration: 695615073, states[0] = -27.307462, states[40]= 0.000647
Saving checkpoint... 
Iteration: 708291617, states[0] = -95.141298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 719790786, states[0] = -95.140666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 731279159, states[0] = -95.131320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 743245411, states[0] = -95.096969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 754889673, states[0] = -95.188395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 766271849, states[0] = -95.124835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 778453384, states[0] = -95.202268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 789994461, states[0] = -95.207710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 802120698, states[0] = -32.514206, states[40]= 0.000386
Saving checkpoint... 
Iteration: 814061517, states[0] = 9.328803, states[40]= 0.004971
Saving checkpoint... 
Iteration: 826723138, states[0] = -95.066964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 838972603, states[0] = -95.205046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 850557331, states[0] = 11.003285, states[40]= 0.005027
Saving checkpoint... 
Iteration: 862495856, states[0] = -95.207821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 875260118, states[0] = -95.113331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 886822942, states[0] = -95.161365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 901322503, states[0] = -95.161116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 913096479, states[0] = -10.595147, states[40]= 0.002203
Saving checkpoint... 
Iteration: 924824784, states[0] = -95.162346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 937029504, states[0] = 20.724590, states[40]= 0.006543
Saving checkpoint... 
Iteration: 949358053, states[0] = -95.177637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 961934128, states[0] = -95.198800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 973448737, states[0] = -95.201404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 985332023, states[0] = -95.166077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 997503250, states[0] = 38.450260, states[40]= 0.123232
Saving checkpoint... 
Iteration: 1008947329, states[0] = -95.201148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1020475675, states[0] = -95.205352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1033022877, states[0] = 22.419972, states[40]= 0.008550
Saving checkpoint... 
Iteration: 1044866752, states[0] = -95.180841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1057224432, states[0] = -95.068759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1069330942, states[0] = -95.165486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1081190677, states[0] = -95.011182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1092500884, states[0] = 49.833934, states[40]= 0.016242
Saving checkpoint... 
Iteration: 1104593384, states[0] = -8.060151, states[40]= 0.002733
Saving checkpoint... 
Iteration: 1116241857, states[0] = -95.092413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1127206417, states[0] = -95.039995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1139388803, states[0] = -95.187934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1151482248, states[0] = -95.206108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1164176879, states[0] = -94.901386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1175549851, states[0] = 13.861526, states[40]= 0.005133
Saving checkpoint... 
Iteration: 1187234075, states[0] = -95.082288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1198868563, states[0] = -95.181402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1210909766, states[0] = -95.193443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1222642957, states[0] = -56.490410, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1234483407, states[0] = -95.206204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1245766237, states[0] = -95.119271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1257727967, states[0] = -95.073779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1269561810, states[0] = 9.209155, states[40]= 0.004967
Saving checkpoint... 
Iteration: 1281280272, states[0] = -95.131964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1293359820, states[0] = -95.178134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1304813464, states[0] = -95.155688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1316842622, states[0] = -95.170950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1328591275, states[0] = -6.437538, states[40]= 0.003084
Saving checkpoint... 
Iteration: 1340845609, states[0] = -95.172269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1353123177, states[0] = -34.859862, states[40]= 0.000288
Saving checkpoint... 
Iteration: 1364966680, states[0] = -95.203948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1377369101, states[0] = -95.181495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1388179000, states[0] = -94.949074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1399519417, states[0] = 23.148341, states[40]= 0.011173
Saving checkpoint... 
Iteration: 1411062882, states[0] = 8.768059, states[40]= 0.004951
Saving checkpoint... 
Iteration: 1423246755, states[0] = -95.098205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1436228050, states[0] = -95.073801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1447672949, states[0] = -94.653916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1459184293, states[0] = -94.993224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1470843572, states[0] = -95.171294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1483282158, states[0] = -95.133428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1495327195, states[0] = -95.163320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1506864604, states[0] = -95.394731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1518802079, states[0] = -95.333186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1530479295, states[0] = -95.301090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1542074946, states[0] = -5.818795, states[40]= 0.003639
Saving checkpoint... 
Iteration: 1554292229, states[0] = -95.450533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1566017697, states[0] = 23.200538, states[40]= 0.015097
Saving checkpoint... 
Iteration: 1578218537, states[0] = -95.388346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1589413137, states[0] = 24.570597, states[40]= 0.029698
Saving checkpoint... 
Iteration: 1601839775, states[0] = -89.156826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1613850815, states[0] = -95.094763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1626085230, states[0] = -16.614375, states[40]= 0.001427
Saving checkpoint... 
Iteration: 1638223001, states[0] = -95.399283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1651073618, states[0] = -95.314336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1663836593, states[0] = 15.855402, states[40]= 0.006623
Saving checkpoint... 
Iteration: 1676011130, states[0] = -95.383361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1687408972, states[0] = -95.380190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1698329074, states[0] = 19.071479, states[40]= 0.007687
Saving checkpoint... 
Iteration: 1710301126, states[0] = 51.826696, states[40]= 0.024108
Saving checkpoint... 
Iteration: 1722026980, states[0] = 19.895808, states[40]= 0.008190
Saving checkpoint... 
Iteration: 1733496695, states[0] = -28.614196, states[40]= 0.000562
Saving checkpoint... 
Iteration: 1744503226, states[0] = 39.680349, states[40]= 0.099711
Saving checkpoint... 
Iteration: 1756337830, states[0] = -86.122981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1768135083, states[0] = -95.414710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1779385482, states[0] = -16.945899, states[40]= 0.001385
Saving checkpoint... 
Iteration: 1791637320, states[0] = 15.519896, states[40]= 0.006555
Saving checkpoint... 
Iteration: 1803683445, states[0] = -95.037646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1816114628, states[0] = -29.816198, states[40]= 0.000526
Saving checkpoint... 
Iteration: 1828621997, states[0] = -35.865486, states[40]= 0.000254
Saving checkpoint... 
Iteration: 1840648158, states[0] = -65.565420, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1853394161, states[0] = -95.202599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1865328162, states[0] = -95.173191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1876742983, states[0] = -95.100331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1889875646, states[0] = -95.188093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1901639804, states[0] = -52.996634, states[40]= 0.000020
Saving checkpoint... 
Iteration: 1913844406, states[0] = -95.173728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1926295199, states[0] = -95.144877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1939107360, states[0] = -20.367997, states[40]= 0.000973
Saving checkpoint... 
Iteration: 1951135208, states[0] = -47.378202, states[40]= 0.000047
Saving checkpoint... 
Iteration: 1963538565, states[0] = 17.879803, states[40]= 0.005549
Saving checkpoint... 
Iteration: 1975387647, states[0] = -95.187492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1987180145, states[0] = -94.964670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2000153488, states[0] = -71.001536, states[40]= 0.000001
Saving checkpoint... 
Iteration: 2011363439, states[0] = -95.179202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2022671202, states[0] = -94.391106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2034698970, states[0] = -95.026461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2046136293, states[0] = -48.544441, states[40]= 0.000040
Saving checkpoint... 
Iteration: 2057483191, states[0] = -95.205721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2070132642, states[0] = -44.456079, states[40]= 0.000074
Saving checkpoint... 
Iteration: 2082991766, states[0] = -95.206683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2094725272, states[0] = -95.069392, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -95.083426
 - CaMKt in component CaMK (millimolar): 0.006941
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.669719
 - nass in component intracellular_ions (millimolar): 6.669780
 - ki in component intracellular_ions (millimolar): 145.309860
 - kss in component intracellular_ions (millimolar): 145.309839
 - cansr in component intracellular_ions (millimolar): 1.307480
 - cajsr in component intracellular_ions (millimolar): 1.268904
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003553
 - hf in component INa (dimensionless): 0.883116
 - hs in component INa (dimensionless): 0.883112
 - j in component INa (dimensionless): 0.883087
 - hsp in component INa (dimensionless): 0.731730
 - jp in component INa (dimensionless): 0.883070
 - mL in component INaL (dimensionless): 0.000048
 - hL in component INaL (dimensionless): 0.713673
 - hLp in component INaL (dimensionless): 0.454438
 - a in component Ito (dimensionless): 0.000616
 - iF in component Ito (dimensionless): 0.999874
 - iS in component Ito (dimensionless): 0.616226
 - ap in component Ito (dimensionless): 0.000314
 - iFp in component Ito (dimensionless): 0.999874
 - iSp in component Ito (dimensionless): 0.689800
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.926461
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999855
 - jca in component ICaL (dimensionless): 0.999973
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001599
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.350586
 - xs1 in component IKs (dimensionless): 0.257146
 - xs2 in component IKs (dimensionless): 0.000086
 - xk1 in component IK1 (dimensionless): 0.997289
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
23:28:07 (1182521): called boinc_finish(0)

</stderr_txt>
]]>


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