𝕏

Task 54816489

Name HuVeMOp_20240626113555201639_ORdGradInc_k_24-Pueyo_APDR-conf_227_0
Workunit 26027547
Created 26 Jun 2024, 9:37:39 UTC
Sent 26 Jun 2024, 11:21:53 UTC
Report deadline 29 Jun 2024, 20:57:53 UTC
Received 27 Jun 2024, 19:57:25 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 239744
Run time 3 hours 14 min 2 sec
CPU time 3 hours 9 min 3 sec
Validate state Valid
Credit 56.90
Device peak FLOPS 2.97 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 3.91 MB
Peak swap size 1.95 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.22.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626113555201639_ORdGradInc_k_24-Pueyo_APDR-conf_227.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626113555201639_ORdGradInc_k_24-Pueyo_APDR-conf_227_0_r103455614_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626113555201639_ORdGradInc_k_24-Pueyo_APDR-conf_227_0_r103455614_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 100.198783
     * GNaL_b in INaL: 0.005621
     * Gto_b in Ito: 0.092744
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.034135
     * GKs_b in IKs: 0.001842
     * GK1_b in IK1: 0.152084
     * Gncx_b in INaCa_i: 0.000959
     * Pnak_b in INaK: 67.460875
     * GKb_b in IKb: 0.003878
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.039605
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12132926, states[0] = -60.733721, states[40]= 0.000004
Saving checkpoint... 
Iteration: 22785582, states[0] = -94.990972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33700219, states[0] = -94.846369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 45573686, states[0] = -0.656776, states[40]= 0.004140
Saving checkpoint... 
Iteration: 58117615, states[0] = -40.566361, states[40]= 0.000117
Saving checkpoint... 
Iteration: 70634948, states[0] = -59.247730, states[40]= 0.000006
Saving checkpoint... 
Iteration: 83134070, states[0] = -58.007792, states[40]= 0.000007
Saving checkpoint... 
Iteration: 95619967, states[0] = -42.382596, states[40]= 0.000090
Saving checkpoint... 
Iteration: 108076264, states[0] = -1.684749, states[40]= 0.003979
Saving checkpoint... 
Iteration: 120231685, states[0] = -94.871700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 132396529, states[0] = -95.003155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 144804425, states[0] = -94.955015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 157257907, states[0] = -94.907877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 169507217, states[0] = 23.222833, states[40]= 0.102812
Saving checkpoint... 
Iteration: 181844708, states[0] = -94.980137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 194180852, states[0] = -94.757578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 206324743, states[0] = -94.968267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 217752284, states[0] = -94.899720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 229339973, states[0] = -94.977202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 240597900, states[0] = -20.083564, states[40]= 0.000947
Saving checkpoint... 
Iteration: 252651882, states[0] = -81.423401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 262011457, states[0] = 21.589153, states[40]= 0.036712
Saving checkpoint... 
Iteration: 272172873, states[0] = -94.673085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 284077652, states[0] = -2.465764, states[40]= 0.003850
Saving checkpoint... 
Iteration: 295967805, states[0] = -95.017785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 307928788, states[0] = -95.010032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 320118790, states[0] = -40.835837, states[40]= 0.000113
Saving checkpoint... 
Iteration: 331728301, states[0] = -94.863039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 343637886, states[0] = -61.868204, states[40]= 0.000004
Saving checkpoint... 
Iteration: 355537189, states[0] = 15.672921, states[40]= 0.005130
Saving checkpoint... 
Iteration: 367722774, states[0] = -94.853297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 379944229, states[0] = -95.013375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 392184090, states[0] = -94.768915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 404427772, states[0] = -95.009708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 416609567, states[0] = -31.547729, states[40]= 0.000384
Saving checkpoint... 
Iteration: 428835632, states[0] = -94.974491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 441124873, states[0] = -47.287067, states[40]= 0.000042
Saving checkpoint... 
Iteration: 453477139, states[0] = -95.019116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 465834526, states[0] = -94.973823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 478179002, states[0] = -94.747640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 490273960, states[0] = -94.925374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 502629725, states[0] = -52.613129, states[40]= 0.000018
Saving checkpoint... 
Iteration: 514998541, states[0] = -95.021972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 527349470, states[0] = -94.981871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 539422537, states[0] = -95.008324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 542341772, states[0] = -94.977838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 553101813, states[0] = -23.919016, states[40]= 0.000734
Saving checkpoint... 
Iteration: 565317258, states[0] = -94.962794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 576597153, states[0] = -19.345881, states[40]= 0.001001
Saving checkpoint... 
Iteration: 587876626, states[0] = -94.993850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599859772, states[0] = -94.986751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 609728234, states[0] = -94.862711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 621176669, states[0] = -94.730273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 632925847, states[0] = -95.009074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 644953563, states[0] = -95.015010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 656693308, states[0] = -94.792496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 667066690, states[0] = 3.708448, states[40]= 0.004568
Saving checkpoint... 
Iteration: 677842613, states[0] = -94.978192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 688158895, states[0] = -91.049639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 700202085, states[0] = -94.812048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 711089385, states[0] = -11.847723, states[40]= 0.001973
Saving checkpoint... 
Iteration: 721735366, states[0] = -94.874412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 733359674, states[0] = -94.986608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 744692408, states[0] = -94.790331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 755231353, states[0] = -94.867860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 766230201, states[0] = -94.865929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 775643511, states[0] = -68.836094, states[40]= 0.000001
Saving checkpoint... 
Iteration: 786409730, states[0] = -95.004720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 797120485, states[0] = -42.601725, states[40]= 0.000087
Saving checkpoint... 
Iteration: 806798141, states[0] = -94.948073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 816505285, states[0] = 25.970724, states[40]= 0.151924
Saving checkpoint... 
Iteration: 826737308, states[0] = -94.877399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 836542160, states[0] = 13.904046, states[40]= 0.004947
Saving checkpoint... 
Iteration: 848085852, states[0] = -8.679011, states[40]= 0.002606
Saving checkpoint... 
Iteration: 858780417, states[0] = -94.931791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 869194153, states[0] = -94.794289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 881066868, states[0] = 3.621003, states[40]= 0.004562
Saving checkpoint... 
Iteration: 893173693, states[0] = -94.689921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 905230600, states[0] = -94.866494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 917393173, states[0] = -94.999544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 929310211, states[0] = -94.957486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 941195694, states[0] = -94.797752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 953062138, states[0] = 5.850766, states[40]= 0.004684
Saving checkpoint... 
Iteration: 965009631, states[0] = 21.984102, states[40]= 0.057084
Saving checkpoint... 
Iteration: 977224143, states[0] = -94.855296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 989361126, states[0] = -94.987076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1001431446, states[0] = -95.010131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1013272539, states[0] = -94.923454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1024939098, states[0] = -95.011820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1037092691, states[0] = -14.988423, states[40]= 0.001464
Saving checkpoint... 
Iteration: 1049520473, states[0] = 20.286617, states[40]= 0.008591
Saving checkpoint... 
Iteration: 1061965551, states[0] = -95.016829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1074409887, states[0] = -95.004552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1086665402, states[0] = -94.090780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1099063968, states[0] = 5.010233, states[40]= 0.004645
Saving checkpoint... 
Iteration: 1111256346, states[0] = -94.904223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1123083565, states[0] = -6.775270, states[40]= 0.003011
Saving checkpoint... 
Iteration: 1135161863, states[0] = -93.009937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1147153432, states[0] = -83.943992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1159066077, states[0] = 4.007605, states[40]= 0.004587
Saving checkpoint... 
Iteration: 1171102470, states[0] = -24.563161, states[40]= 0.000703
Saving checkpoint... 
Iteration: 1183180885, states[0] = -94.756615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1195136551, states[0] = -60.311089, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1207292900, states[0] = -94.943275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1219263105, states[0] = -94.912531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1231117534, states[0] = -39.540847, states[40]= 0.000136
Saving checkpoint... 
Iteration: 1242996825, states[0] = -95.021224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253740823, states[0] = -94.882479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1264478619, states[0] = -95.018739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1275403104, states[0] = -95.002421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1285491228, states[0] = -95.020479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1297715335, states[0] = -94.838704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1307682361, states[0] = -94.762405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1318114280, states[0] = -36.240095, states[40]= 0.000215
Saving checkpoint... 
Iteration: 1328729556, states[0] = -94.864425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1339032964, states[0] = 17.069752, states[40]= 0.005401
Saving checkpoint... 
Iteration: 1348757308, states[0] = -94.905277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1360548581, states[0] = 11.484909, states[40]= 0.004833
Saving checkpoint... 
Iteration: 1372546732, states[0] = 12.195076, states[40]= 0.004856
Saving checkpoint... 
Iteration: 1384555910, states[0] = 8.548008, states[40]= 0.004766
Saving checkpoint... 
Iteration: 1396553320, states[0] = 9.610373, states[40]= 0.004789
Saving checkpoint... 
Iteration: 1408742080, states[0] = -94.884248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1420788084, states[0] = -94.938764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1432768683, states[0] = -94.918868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1444536049, states[0] = 16.061108, states[40]= 0.005191
Saving checkpoint... 
Iteration: 1455596833, states[0] = -19.031287, states[40]= 0.001026
Saving checkpoint... 
Iteration: 1465394780, states[0] = -94.999668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1475610232, states[0] = -32.205205, states[40]= 0.000357
Saving checkpoint... 
Iteration: 1486867544, states[0] = -94.989508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1496890569, states[0] = -94.998242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1507728204, states[0] = -95.196775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1518399646, states[0] = -38.879554, states[40]= 0.000151
Saving checkpoint... 
Iteration: 1530573898, states[0] = -95.276472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1541393355, states[0] = -95.301535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1553560514, states[0] = -95.091381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1565687126, states[0] = -95.309859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1577681459, states[0] = -95.308944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1589995167, states[0] = -95.321795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1602125790, states[0] = -75.840034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1614072226, states[0] = -10.201204, states[40]= 0.002597
Saving checkpoint... 
Iteration: 1625983921, states[0] = -95.316877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1637859056, states[0] = -95.101842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1649973245, states[0] = -95.308758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1662800460, states[0] = -95.209506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1674748682, states[0] = -94.992181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1686982993, states[0] = -22.351348, states[40]= 0.000858
Saving checkpoint... 
Iteration: 1699295263, states[0] = -36.312571, states[40]= 0.000215
Saving checkpoint... 
Iteration: 1711645749, states[0] = -94.866124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1724006290, states[0] = -95.221162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1736347136, states[0] = -95.282520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1748691570, states[0] = -95.324132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1761059064, states[0] = 0.999788, states[40]= 0.004898
Saving checkpoint... 
Iteration: 1773423175, states[0] = -71.898567, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1785753490, states[0] = -95.070456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1798119759, states[0] = -95.244575, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1810474095, states[0] = -95.076636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1822817914, states[0] = -95.005027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1835330092, states[0] = -95.000245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1847733330, states[0] = -94.891590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1860364726, states[0] = -95.002452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1872772085, states[0] = -94.932444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1885109612, states[0] = -31.959081, states[40]= 0.000367
Saving checkpoint... 
Iteration: 1897434196, states[0] = -95.014928, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1909471155, states[0] = -95.020501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1921712360, states[0] = -94.834822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1934138215, states[0] = -62.371254, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1946323372, states[0] = -94.966986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1957367641, states[0] = -94.989991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1966157190, states[0] = -89.343860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1976476578, states[0] = -95.018331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1987175469, states[0] = -94.716889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1996932182, states[0] = -95.009767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2007563457, states[0] = 5.243869, states[40]= 0.004656
Saving checkpoint... 
Iteration: 2018453249, states[0] = -95.014012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2027851786, states[0] = -94.981954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2038471792, states[0] = -95.017134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2048997484, states[0] = -95.020699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2058855021, states[0] = -94.983432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2068702599, states[0] = -94.812096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2079465268, states[0] = -95.015984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2090302353, states[0] = -94.950517, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.896797
 - CaMKt in component CaMK (millimolar): 0.007158
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.652543
 - nass in component intracellular_ions (millimolar): 6.652604
 - ki in component intracellular_ions (millimolar): 145.321336
 - kss in component intracellular_ions (millimolar): 145.321316
 - cansr in component intracellular_ions (millimolar): 1.323906
 - cajsr in component intracellular_ions (millimolar): 1.286000
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003620
 - hf in component INa (dimensionless): 0.879913
 - hs in component INa (dimensionless): 0.879908
 - j in component INa (dimensionless): 0.879878
 - hsp in component INa (dimensionless): 0.725664
 - jp in component INa (dimensionless): 0.879858
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.710489
 - hLp in component INaL (dimensionless): 0.453950
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.624900
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.700707
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.938862
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999898
 - jca in component ICaL (dimensionless): 0.999980
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001638
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.317394
 - xs1 in component IKs (dimensionless): 0.235315
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997338
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
21:41:03 (9144): called boinc_finish(0)

</stderr_txt>
]]>


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