𝕏

Task 54814113

Name HuVeMOp_20240626064103635658_ORdGradInc_k_24-Pueyo_APDR-conf_76_2
Workunit 26014834
Created 26 Jun 2024, 7:33:33 UTC
Sent 26 Jun 2024, 10:58:09 UTC
Report deadline 29 Jun 2024, 20:34:09 UTC
Received 28 Jun 2024, 14:13:03 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 237135
Run time 2 hours 57 min 12 sec
CPU time 1 hours 42 min 44 sec
Validate state Valid
Credit 63.44
Device peak FLOPS 4.35 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 8.31 MB
Peak swap size 4.37 MB
Peak disk usage 0.26 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626064103635658_ORdGradInc_k_24-Pueyo_APDR-conf_76.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626064103635658_ORdGradInc_k_24-Pueyo_APDR-conf_76_2_r1128621639_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626064103635658_ORdGradInc_k_24-Pueyo_APDR-conf_76_2_r1128621639_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 103.985972
     * GNaL_b in INaL: 0.008492
     * Gto_b in Ito: 0.079507
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032448
     * GKs_b in IKs: 0.001811
     * GK1_b in IK1: 0.170507
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 61.584156
     * GKb_b in IKb: 0.003954
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035504
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 17404052, states[0] = -95.090865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35568737, states[0] = 5.283433, states[40]= 0.004788
Saving checkpoint... 
Iteration: 52584851, states[0] = -3.289410, states[40]= 0.003761
Saving checkpoint... 
Iteration: 67229241, states[0] = -94.946900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 78764153, states[0] = -94.991494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 91244424, states[0] = -94.966864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 105305965, states[0] = -95.027212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 120821394, states[0] = -95.036971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 138298304, states[0] = -95.020759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 153136070, states[0] = -49.050441, states[40]= 0.000038
Saving checkpoint... 
Iteration: 171932867, states[0] = -95.078229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 187074928, states[0] = 2.556686, states[40]= 0.004578
Saving checkpoint... 
Iteration: 197797153, states[0] = -95.019432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 214302167, states[0] = -95.023200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 225745813, states[0] = -94.966798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 241260303, states[0] = -94.984490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 253743028, states[0] = -94.963044, states[40]= 0.000000
Saving checkpoint... 
Iteration: 265605760, states[0] = -20.107696, states[40]= 0.001006
Saving checkpoint... 
Iteration: 279903364, states[0] = -95.070760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 296702705, states[0] = -94.897005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311979756, states[0] = -95.086025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 325522601, states[0] = 21.884474, states[40]= 0.007932
Saving checkpoint... 
Iteration: 340559377, states[0] = 9.507274, states[40]= 0.004956
Saving checkpoint... 
Iteration: 356293700, states[0] = -95.016495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 370830974, states[0] = -95.041609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 386771046, states[0] = -94.995909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 403490324, states[0] = -95.087339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 417949313, states[0] = -95.081118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 425350881, states[0] = -95.051661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432646642, states[0] = -61.398848, states[40]= 0.000005
Saving checkpoint... 
Iteration: 438993836, states[0] = -95.087743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 447343187, states[0] = -95.047975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 462329825, states[0] = -95.040902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474207895, states[0] = -94.906642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 488422960, states[0] = -95.075622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 498730541, states[0] = -94.944899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 508191183, states[0] = -94.873310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 514240024, states[0] = -94.958726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 519792495, states[0] = -95.015404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 526344035, states[0] = -95.048339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 534053844, states[0] = 11.689494, states[40]= 0.005007
Saving checkpoint... 
Iteration: 543212947, states[0] = -94.915761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 554165191, states[0] = -90.318786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 571096863, states[0] = -12.219122, states[40]= 0.001915
Saving checkpoint... 
Iteration: 582212687, states[0] = -94.915271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 593557183, states[0] = 10.385231, states[40]= 0.004977
Saving checkpoint... 
Iteration: 606839097, states[0] = -95.045802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 617220481, states[0] = -94.928723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 628914928, states[0] = -95.073583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 643157255, states[0] = -76.955846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 656622698, states[0] = -35.429308, states[40]= 0.000279
Saving checkpoint... 
Iteration: 669968178, states[0] = -95.084103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 683732993, states[0] = -94.948474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 699117559, states[0] = -30.694143, states[40]= 0.000491
Saving checkpoint... 
Iteration: 712951802, states[0] = -95.081367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 723548724, states[0] = 13.628345, states[40]= 0.005061
Saving checkpoint... 
Iteration: 731306226, states[0] = -95.025742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 741110388, states[0] = -24.241372, states[40]= 0.000811
Saving checkpoint... 
Iteration: 750928708, states[0] = -95.076749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 765531991, states[0] = 19.389064, states[40]= 0.005831
Saving checkpoint... 
Iteration: 779747010, states[0] = -94.967944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 794267620, states[0] = -94.992087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 809966674, states[0] = -95.083776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 825192056, states[0] = -94.875089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 838145026, states[0] = -59.403745, states[40]= 0.000007
Saving checkpoint... 
Iteration: 851289559, states[0] = -95.012744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 866091753, states[0] = -7.997495, states[40]= 0.002770
Saving checkpoint... 
Iteration: 879605540, states[0] = -19.909830, states[40]= 0.001018
Saving checkpoint... 
Iteration: 894085154, states[0] = -3.264994, states[40]= 0.003760
Saving checkpoint... 
Iteration: 907638025, states[0] = -51.211039, states[40]= 0.000027
Saving checkpoint... 
Iteration: 920568154, states[0] = 5.777269, states[40]= 0.004812
Saving checkpoint... 
Iteration: 927731669, states[0] = -94.946320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 936322348, states[0] = -95.036207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 944203605, states[0] = -94.898276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 952745253, states[0] = -94.965524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 963374355, states[0] = -95.060961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 976786964, states[0] = -95.010445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 989587571, states[0] = -4.895672, states[40]= 0.003438
Saving checkpoint... 
Iteration: 1001925802, states[0] = -95.075929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1015665259, states[0] = -90.396730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1027217008, states[0] = -94.922546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1039551443, states[0] = 12.607082, states[40]= 0.005029
Saving checkpoint... 
Iteration: 1053352697, states[0] = -95.052063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1066404799, states[0] = -95.070619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1080766180, states[0] = -94.990365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1095081277, states[0] = -0.875620, states[40]= 0.004163
Saving checkpoint... 
Iteration: 1107699719, states[0] = -94.890668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1120846673, states[0] = -95.049216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1134754816, states[0] = -94.977452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1146199857, states[0] = -94.890912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1158099369, states[0] = -14.406458, states[40]= 0.001563
Saving checkpoint... 
Iteration: 1171356427, states[0] = -95.053638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1182775853, states[0] = -95.000138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1193014921, states[0] = 23.304472, states[40]= 0.018473
Saving checkpoint... 
Iteration: 1205521016, states[0] = 22.223293, states[40]= 0.008811
Saving checkpoint... 
Iteration: 1217475753, states[0] = -95.084851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1229283932, states[0] = -95.007613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1241464678, states[0] = -95.083172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1250942682, states[0] = -95.079307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1263532241, states[0] = 19.312978, states[40]= 0.005805
Saving checkpoint... 
Iteration: 1275622401, states[0] = -35.151056, states[40]= 0.000289
Saving checkpoint... 
Iteration: 1288255912, states[0] = -94.978656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1300936140, states[0] = -95.077964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1312839387, states[0] = -95.045473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1323823833, states[0] = -95.036839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1335014920, states[0] = 23.304655, states[40]= 0.018476
Saving checkpoint... 
Iteration: 1343852332, states[0] = -95.051701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1354459494, states[0] = -95.082257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1367446934, states[0] = -95.080037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1380272452, states[0] = -94.996654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1393961544, states[0] = -95.082567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406065753, states[0] = 6.838372, states[40]= 0.004865
Saving checkpoint... 
Iteration: 1417635795, states[0] = -48.718061, states[40]= 0.000040
Saving checkpoint... 
Iteration: 1431402808, states[0] = -95.069817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1444978834, states[0] = -95.085129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1459400195, states[0] = -95.069054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1473315920, states[0] = -95.031817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1487103131, states[0] = -17.754402, states[40]= 0.001177
Saving checkpoint... 
Iteration: 1499597428, states[0] = -12.707121, states[40]= 0.001830
Saving checkpoint... 
Iteration: 1513242828, states[0] = 13.129683, states[40]= 0.005994
Saving checkpoint... 
Iteration: 1526664285, states[0] = -95.295278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1539687364, states[0] = -18.894844, states[40]= 0.001177
Saving checkpoint... 
Iteration: 1552651283, states[0] = -94.875619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1566605866, states[0] = 28.776731, states[40]= 0.120862
Saving checkpoint... 
Iteration: 1579919736, states[0] = -55.605607, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1592583260, states[0] = -95.202966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1602793209, states[0] = -95.224799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1614604526, states[0] = 31.989386, states[40]= 0.138287
Saving checkpoint... 
Iteration: 1624454516, states[0] = -95.314402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1637318607, states[0] = -95.270604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1648600827, states[0] = -33.891607, states[40]= 0.000332
Saving checkpoint... 
Iteration: 1660031683, states[0] = -73.644687, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1673713987, states[0] = 23.520908, states[40]= 0.023488
Saving checkpoint... 
Iteration: 1685353338, states[0] = -95.314402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1698418782, states[0] = -54.827453, states[40]= 0.000016
Saving checkpoint... 
Iteration: 1711459577, states[0] = -95.320624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1724050625, states[0] = -95.311720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1738441419, states[0] = -95.301583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1753677906, states[0] = -95.194730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1767791199, states[0] = -95.223525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1780602343, states[0] = -35.528888, states[40]= 0.000271
Saving checkpoint... 
Iteration: 1794245496, states[0] = -95.306188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1808521403, states[0] = 21.618677, states[40]= 0.008088
Saving checkpoint... 
Iteration: 1822541975, states[0] = 15.512600, states[40]= 0.005215
Saving checkpoint... 
Iteration: 1835686560, states[0] = -94.884322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1849895196, states[0] = -95.082927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1865064023, states[0] = 7.339594, states[40]= 0.004897
Saving checkpoint... 
Iteration: 1877640100, states[0] = -54.223891, states[40]= 0.000017
Saving checkpoint... 
Iteration: 1885925016, states[0] = -95.080691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1896494865, states[0] = -95.090966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1909500413, states[0] = -43.461402, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1920795677, states[0] = -95.019047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1933410689, states[0] = -95.073007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1948419385, states[0] = -95.074676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1963170965, states[0] = -94.034632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1977481269, states[0] = -95.085457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1990879501, states[0] = -95.062334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2004060637, states[0] = 8.990524, states[40]= 0.004942
Saving checkpoint... 
Iteration: 2017541793, states[0] = 16.143370, states[40]= 0.005215
Saving checkpoint... 
Iteration: 2031989007, states[0] = -95.086098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2045368441, states[0] = -95.057990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2057524901, states[0] = 21.347043, states[40]= 0.007081
Saving checkpoint... 
Iteration: 2069601906, states[0] = -16.661417, states[40]= 0.001282
Saving checkpoint... 
Iteration: 2081649610, states[0] = -65.235304, states[40]= 0.000003
Saving checkpoint... 
Iteration: 2092973870, states[0] = -95.083939, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.963162
 - CaMKt in component CaMK (millimolar): 0.007322
 - cass in component intracellular_ions (millimolar): 0.000075
 - nai in component intracellular_ions (millimolar): 6.860969
 - nass in component intracellular_ions (millimolar): 6.861032
 - ki in component intracellular_ions (millimolar): 145.111458
 - kss in component intracellular_ions (millimolar): 145.111437
 - cansr in component intracellular_ions (millimolar): 1.334170
 - cajsr in component intracellular_ions (millimolar): 1.295404
 - cai in component intracellular_ions (millimolar): 0.000076
 - m in component INa (dimensionless): 0.003596
 - hf in component INa (dimensionless): 0.881061
 - hs in component INa (dimensionless): 0.881056
 - j in component INa (dimensionless): 0.881028
 - hsp in component INa (dimensionless): 0.727831
 - jp in component INa (dimensionless): 0.881009
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.710449
 - hLp in component INaL (dimensionless): 0.450668
 - a in component Ito (dimensionless): 0.000621
 - iF in component Ito (dimensionless): 0.999871
 - iS in component Ito (dimensionless): 0.615917
 - ap in component Ito (dimensionless): 0.000316
 - iFp in component Ito (dimensionless): 0.999871
 - iSp in component Ito (dimensionless): 0.689637
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.928985
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999864
 - jca in component ICaL (dimensionless): 0.999974
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001699
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.341729
 - xs1 in component IKs (dimensionless): 0.253047
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997321
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
23:12:52 (35280): called boinc_finish(0)

</stderr_txt>
]]>


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