𝕏

Task 54813112

Name HuVeMOp_20240626065019623306_ORdGradInc_k_24-Pueyo_APDR-conf_97_0
Workunit 26026340
Created 26 Jun 2024, 4:58:18 UTC
Sent 26 Jun 2024, 10:58:09 UTC
Report deadline 29 Jun 2024, 20:34:09 UTC
Received 28 Jun 2024, 14:09:58 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 237135
Run time 2 hours 54 min 27 sec
CPU time 1 hours 42 min 34 sec
Validate state Valid
Credit 62.25
Device peak FLOPS 4.35 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 8.31 MB
Peak swap size 4.36 MB
Peak disk usage 0.27 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626065019623306_ORdGradInc_k_24-Pueyo_APDR-conf_97.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626065019623306_ORdGradInc_k_24-Pueyo_APDR-conf_97_0_r1969643001_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626065019623306_ORdGradInc_k_24-Pueyo_APDR-conf_97_0_r1969643001_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 121.451195
     * GNaL_b in INaL: 0.006342
     * Gto_b in Ito: 0.087033
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.031835
     * GKs_b in IKs: 0.001816
     * GK1_b in IK1: 0.176020
     * Gncx_b in INaCa_i: 0.000950
     * Pnak_b in INaK: 63.280458
     * GKb_b in IKb: 0.003767
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035795
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 17948902, states[0] = -95.151704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 37598316, states[0] = -18.538985, states[40]= 0.001098
Saving checkpoint... 
Iteration: 54687523, states[0] = -94.928198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 72052760, states[0] = 10.585652, states[40]= 0.004991
Saving checkpoint... 
Iteration: 88518180, states[0] = 21.532427, states[40]= 0.011772
Saving checkpoint... 
Iteration: 107343021, states[0] = -95.094186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 118400618, states[0] = -95.114387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 135863023, states[0] = -95.101645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 150835290, states[0] = -95.089110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167466430, states[0] = -95.126710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 185906826, states[0] = -95.114837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 199381024, states[0] = -95.107303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 212110734, states[0] = -29.347583, states[40]= 0.000522
Saving checkpoint... 
Iteration: 223059579, states[0] = 7.908069, states[40]= 0.004903
Saving checkpoint... 
Iteration: 241185568, states[0] = -94.915226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 257978246, states[0] = -95.127990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 274256368, states[0] = -95.028214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 283262690, states[0] = -95.035004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 296285233, states[0] = -95.055940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 310190297, states[0] = -94.925242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 324824739, states[0] = -95.082871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 338046582, states[0] = 13.074287, states[40]= 0.005085
Saving checkpoint... 
Iteration: 352191570, states[0] = -94.927799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 368768821, states[0] = -95.041119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 386330118, states[0] = -95.085747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 404398885, states[0] = -95.112383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 419903959, states[0] = -95.113738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432684319, states[0] = -94.912144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 443333077, states[0] = -95.087251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 454220722, states[0] = -94.980345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 465030492, states[0] = 18.602136, states[40]= 0.006035
Saving checkpoint... 
Iteration: 475543402, states[0] = 14.256100, states[40]= 0.005164
Saving checkpoint... 
Iteration: 489809347, states[0] = -95.073493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 503924593, states[0] = -95.118617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 517983251, states[0] = -95.128434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 529269040, states[0] = -95.041223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 539179209, states[0] = -94.896682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 546138905, states[0] = -58.981072, states[40]= 0.000007
Saving checkpoint... 
Iteration: 552149752, states[0] = -74.059097, states[40]= 0.000001
Saving checkpoint... 
Iteration: 558228330, states[0] = -94.991936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 565478662, states[0] = -95.127812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 573209005, states[0] = -94.960607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 584478740, states[0] = -95.127809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599710233, states[0] = -94.962746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 610337000, states[0] = -95.089116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 621026730, states[0] = 19.661329, states[40]= 0.006673
Saving checkpoint... 
Iteration: 633467245, states[0] = -95.126182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 645833689, states[0] = -95.087427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 656963583, states[0] = -95.125621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 671212148, states[0] = -94.966016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 686318990, states[0] = -95.079326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 700187163, states[0] = -94.918396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 716093881, states[0] = -13.501469, states[40]= 0.001710
Saving checkpoint... 
Iteration: 729587568, states[0] = -7.994043, states[40]= 0.002789
Saving checkpoint... 
Iteration: 743072385, states[0] = 1.931044, states[40]= 0.004524
Saving checkpoint... 
Iteration: 755637685, states[0] = -57.524590, states[40]= 0.000009
Saving checkpoint... 
Iteration: 766809565, states[0] = -95.073447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 777332932, states[0] = -95.086951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 789751020, states[0] = -95.021741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 804871006, states[0] = -95.103341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 817967309, states[0] = -95.126067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 830346909, states[0] = -95.093643, states[40]= 0.000000
Saving checkpoint... 
Iteration: 844099810, states[0] = -19.038737, states[40]= 0.001057
Saving checkpoint... 
Iteration: 859951664, states[0] = -95.123577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 875158006, states[0] = -88.819187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 887349228, states[0] = -95.094636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 901225927, states[0] = -94.988112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 914424669, states[0] = -95.118357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 930951691, states[0] = -95.123533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 944945329, states[0] = -95.122416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 958449351, states[0] = -95.123115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 965785381, states[0] = -95.055601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 973872135, states[0] = -95.103628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 982256710, states[0] = -95.028098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 990472622, states[0] = -95.126708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 999947169, states[0] = -95.122706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1014443615, states[0] = -95.122060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1027263908, states[0] = -95.035747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1039930347, states[0] = -95.119472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1053619021, states[0] = -37.325207, states[40]= 0.000202
Saving checkpoint... 
Iteration: 1067351230, states[0] = -95.095386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1079979144, states[0] = -95.127528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1094078886, states[0] = -1.774857, states[40]= 0.004036
Saving checkpoint... 
Iteration: 1108232842, states[0] = -94.998079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1120040008, states[0] = 15.479890, states[40]= 0.005288
Saving checkpoint... 
Iteration: 1132333247, states[0] = -95.086873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1143192996, states[0] = -94.930122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1155338986, states[0] = -95.089721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167921297, states[0] = -95.117443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1180364230, states[0] = -95.100585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1193634132, states[0] = -53.398925, states[40]= 0.000017
Saving checkpoint... 
Iteration: 1203713898, states[0] = -94.968640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1214119310, states[0] = -37.610308, states[40]= 0.000194
Saving checkpoint... 
Iteration: 1224256324, states[0] = -95.027506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1234964240, states[0] = -95.125331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1244031343, states[0] = 18.346698, states[40]= 0.005931
Saving checkpoint... 
Iteration: 1254658798, states[0] = -89.906410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1267367373, states[0] = -95.101707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1280737779, states[0] = -95.004764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1294547146, states[0] = 12.861978, states[40]= 0.005074
Saving checkpoint... 
Iteration: 1306603455, states[0] = -22.470762, states[40]= 0.000849
Saving checkpoint... 
Iteration: 1318339370, states[0] = -95.089797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1330850425, states[0] = -95.094860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1343267747, states[0] = -95.039403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1353219313, states[0] = -94.977481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1361714220, states[0] = -94.969077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1371543446, states[0] = 14.240146, states[40]= 0.005163
Saving checkpoint... 
Iteration: 1380320005, states[0] = -95.079453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1392693447, states[0] = -94.930850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406201887, states[0] = -94.947104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1419768908, states[0] = -95.040491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1434096676, states[0] = -16.093515, states[40]= 0.001345
Saving checkpoint... 
Iteration: 1443792174, states[0] = -95.060695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1456448951, states[0] = -95.122710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1469891936, states[0] = -95.109687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1484673829, states[0] = -94.853481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1499084500, states[0] = -5.601153, states[40]= 0.003308
Saving checkpoint... 
Iteration: 1512273644, states[0] = -95.325529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1525324247, states[0] = -65.850340, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1536508119, states[0] = -95.271536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1550362534, states[0] = -95.343906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1565699029, states[0] = -95.375465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1580620127, states[0] = -95.305580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1595546832, states[0] = -95.012386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1610417655, states[0] = 21.593623, states[40]= 0.014085
Saving checkpoint... 
Iteration: 1623649109, states[0] = 8.092567, states[40]= 0.005707
Saving checkpoint... 
Iteration: 1638292235, states[0] = -95.379164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1649810239, states[0] = -49.891643, states[40]= 0.000033
Saving checkpoint... 
Iteration: 1663772577, states[0] = -95.365855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1675655150, states[0] = -95.172932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1686579180, states[0] = -95.370997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1696139218, states[0] = -95.334798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1709594330, states[0] = -95.269403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1722204949, states[0] = -95.287997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1734437780, states[0] = -92.320044, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1748070174, states[0] = -95.364263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1762257493, states[0] = 3.276762, states[40]= 0.005291
Saving checkpoint... 
Iteration: 1774646637, states[0] = -95.017742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1788247111, states[0] = -95.343326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1801088746, states[0] = -13.305422, states[40]= 0.001841
Saving checkpoint... 
Iteration: 1814100561, states[0] = -22.718524, states[40]= 0.000848
Saving checkpoint... 
Iteration: 1828405409, states[0] = -95.140565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1843158981, states[0] = -91.891611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1856750085, states[0] = -95.032415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1869788375, states[0] = -95.065939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1883356157, states[0] = -95.102622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1897461062, states[0] = -95.128186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1910370803, states[0] = -95.105134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1920129748, states[0] = -48.670921, states[40]= 0.000037
Saving checkpoint... 
Iteration: 1931397813, states[0] = -95.112465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1945068479, states[0] = 3.867371, states[40]= 0.004694
Saving checkpoint... 
Iteration: 1955031605, states[0] = 18.255727, states[40]= 0.005900
Saving checkpoint... 
Iteration: 1966370443, states[0] = -95.102839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1979491299, states[0] = -95.128739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1992451165, states[0] = -95.122926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2003803342, states[0] = -95.068582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2014736188, states[0] = -95.002189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2028432971, states[0] = -95.119369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2042897092, states[0] = -95.110778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2058764017, states[0] = -95.035137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2073763538, states[0] = -95.034619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2086910807, states[0] = -95.114311, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -95.005144
 - CaMKt in component CaMK (millimolar): 0.007242
 - cass in component intracellular_ions (millimolar): 0.000075
 - nai in component intracellular_ions (millimolar): 6.789212
 - nass in component intracellular_ions (millimolar): 6.789273
 - ki in component intracellular_ions (millimolar): 145.183816
 - kss in component intracellular_ions (millimolar): 145.183796
 - cansr in component intracellular_ions (millimolar): 1.331397
 - cajsr in component intracellular_ions (millimolar): 1.293248
 - cai in component intracellular_ions (millimolar): 0.000076
 - m in component INa (dimensionless): 0.003581
 - hf in component INa (dimensionless): 0.881781
 - hs in component INa (dimensionless): 0.881777
 - j in component INa (dimensionless): 0.881751
 - hsp in component INa (dimensionless): 0.729197
 - jp in component INa (dimensionless): 0.881733
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.712967
 - hLp in component INaL (dimensionless): 0.456119
 - a in component Ito (dimensionless): 0.000619
 - iF in component Ito (dimensionless): 0.999872
 - iS in component Ito (dimensionless): 0.622383
 - ap in component Ito (dimensionless): 0.000315
 - iFp in component Ito (dimensionless): 0.999872
 - iSp in component Ito (dimensionless): 0.697594
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934896
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999884
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001678
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.335399
 - xs1 in component IKs (dimensionless): 0.242165
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997310
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
23:09:49 (24324): called boinc_finish(0)

</stderr_txt>
]]>


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