𝕏

Task 54811154

Name HuVeMOp_20240626065019623306_ORdGradInc_k_24-Pueyo_APDR-conf_887_0
Workunit 26025362
Created 26 Jun 2024, 4:57:26 UTC
Sent 26 Jun 2024, 10:33:10 UTC
Report deadline 29 Jun 2024, 20:09:10 UTC
Received 28 Jun 2024, 14:00:03 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 237135
Run time 2 hours 54 min 2 sec
CPU time 1 hours 43 min 44 sec
Validate state Valid
Credit 62.31
Device peak FLOPS 4.35 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 8.32 MB
Peak swap size 4.37 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626065019623306_ORdGradInc_k_24-Pueyo_APDR-conf_887.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626065019623306_ORdGradInc_k_24-Pueyo_APDR-conf_887_0_r915803229_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626065019623306_ORdGradInc_k_24-Pueyo_APDR-conf_887_0_r915803229_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 122.360069
     * GNaL_b in INaL: 0.007370
     * Gto_b in Ito: 0.072356
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.034129
     * GKs_b in IKs: 0.001896
     * GK1_b in IK1: 0.146108
     * Gncx_b in INaCa_i: 0.000949
     * Pnak_b in INaK: 66.453832
     * GKb_b in IKb: 0.003797
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.039865
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 16323689, states[0] = -95.103781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 32846888, states[0] = -95.084916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 47744216, states[0] = -94.981286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 63924984, states[0] = -95.086890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 79159233, states[0] = -92.710232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 90405334, states[0] = -95.072957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 109889850, states[0] = -95.064901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 123076215, states[0] = -1.312163, states[40]= 0.004209
Saving checkpoint... 
Iteration: 140882564, states[0] = -95.059801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 159689864, states[0] = -94.857043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 173453390, states[0] = -95.076987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 191743996, states[0] = -94.954279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 209819196, states[0] = -95.027346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226243401, states[0] = -94.953154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 243065043, states[0] = 4.942961, states[40]= 0.004918
Saving checkpoint... 
Iteration: 261071068, states[0] = 1.812613, states[40]= 0.004633
Saving checkpoint... 
Iteration: 280614189, states[0] = -36.160625, states[40]= 0.000220
Saving checkpoint... 
Iteration: 296544104, states[0] = 14.138424, states[40]= 0.005500
Saving checkpoint... 
Iteration: 313339839, states[0] = -95.039222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 330853037, states[0] = -95.045806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 349273330, states[0] = -94.989103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 368669985, states[0] = -94.684138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 379727148, states[0] = -94.928165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 394961851, states[0] = -95.077623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 412872010, states[0] = -95.053893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 425067077, states[0] = 3.927593, states[40]= 0.004839
Saving checkpoint... 
Iteration: 438826001, states[0] = -95.031254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 450968914, states[0] = -95.078741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 462496524, states[0] = -95.082546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 477448690, states[0] = -95.075225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 491512763, states[0] = 24.335242, states[40]= 0.030889
Saving checkpoint... 
Iteration: 505357569, states[0] = -95.047787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 525046862, states[0] = 13.014922, states[40]= 0.005395
Saving checkpoint... 
Iteration: 542344025, states[0] = -95.041274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 556621964, states[0] = -44.452278, states[40]= 0.000067
Saving checkpoint... 
Iteration: 569409514, states[0] = -95.066168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 582027035, states[0] = 20.388853, states[40]= 0.007445
Saving checkpoint... 
Iteration: 596124705, states[0] = -47.544103, states[40]= 0.000041
Saving checkpoint... 
Iteration: 603248408, states[0] = -94.959638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 615404028, states[0] = -95.064597, states[40]= 0.000000
Saving checkpoint... 
Iteration: 620999468, states[0] = -95.082813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 633699926, states[0] = -94.877381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 645657715, states[0] = -91.161430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 660088310, states[0] = -10.555918, states[40]= 0.002295
Saving checkpoint... 
Iteration: 670019091, states[0] = 22.659222, states[40]= 0.012086
Saving checkpoint... 
Iteration: 678909489, states[0] = -95.066104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685325298, states[0] = -95.030696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 691246878, states[0] = -94.957537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 698078385, states[0] = -2.642710, states[40]= 0.003976
Saving checkpoint... 
Iteration: 705613929, states[0] = -35.891206, states[40]= 0.000229
Saving checkpoint... 
Iteration: 716761719, states[0] = -94.976170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 726516102, states[0] = 23.421634, states[40]= 0.017415
Saving checkpoint... 
Iteration: 739556109, states[0] = 9.086690, states[40]= 0.005160
Saving checkpoint... 
Iteration: 752421477, states[0] = -95.069183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 762458252, states[0] = -95.076817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 775064134, states[0] = 5.389190, states[40]= 0.004950
Saving checkpoint... 
Iteration: 785782407, states[0] = -94.997828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 796312318, states[0] = -95.022142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 809801371, states[0] = -95.014069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 824402223, states[0] = -95.063963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 837356081, states[0] = -95.046943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 852300251, states[0] = -95.013171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 865674566, states[0] = -94.787855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 879771919, states[0] = -94.987355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 891818242, states[0] = -95.026106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 901478995, states[0] = -95.080018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 912972357, states[0] = -95.079035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 921435961, states[0] = -95.072423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 934832983, states[0] = -95.035111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 946614982, states[0] = -36.976189, states[40]= 0.000197
Saving checkpoint... 
Iteration: 959029609, states[0] = 19.553082, states[40]= 0.006875
Saving checkpoint... 
Iteration: 973627428, states[0] = -50.687033, states[40]= 0.000025
Saving checkpoint... 
Iteration: 988438193, states[0] = -95.072862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1001667524, states[0] = -94.547795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1016250887, states[0] = -94.962687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1028716225, states[0] = -94.908891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1042717631, states[0] = -94.911428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1056743031, states[0] = -94.952036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1070068622, states[0] = 3.129732, states[40]= 0.004768
Saving checkpoint... 
Iteration: 1083187730, states[0] = -94.850482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1091777946, states[0] = -94.993371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1099765678, states[0] = -94.980486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1108369338, states[0] = -95.052474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1116797993, states[0] = -95.011237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1126388136, states[0] = -95.059375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1140153996, states[0] = -86.871858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1153855939, states[0] = -95.046715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1165840221, states[0] = -95.038970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1178657851, states[0] = -91.276018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1191289046, states[0] = -95.003665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1204399317, states[0] = -95.062900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1217390749, states[0] = -95.060195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1230849703, states[0] = -95.043744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1244288219, states[0] = -95.002907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1258348745, states[0] = -95.043264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1271755150, states[0] = -94.967977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1285012396, states[0] = 24.451633, states[40]= 0.033210
Saving checkpoint... 
Iteration: 1297572228, states[0] = 1.164937, states[40]= 0.004558
Saving checkpoint... 
Iteration: 1311016909, states[0] = 23.216677, states[40]= 0.015565
Saving checkpoint... 
Iteration: 1324432821, states[0] = -95.071531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1333792612, states[0] = -95.006676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1344619905, states[0] = -42.188050, states[40]= 0.000094
Saving checkpoint... 
Iteration: 1356646096, states[0] = -74.400015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1365679899, states[0] = -94.826482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1377295069, states[0] = -95.008715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1388986794, states[0] = -95.080839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1401887359, states[0] = -95.058971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1412053743, states[0] = 10.118669, states[40]= 0.005212
Saving checkpoint... 
Iteration: 1424972421, states[0] = -95.078780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437569555, states[0] = 2.636097, states[40]= 0.004721
Saving checkpoint... 
Iteration: 1449555894, states[0] = 9.181474, states[40]= 0.005165
Saving checkpoint... 
Iteration: 1463712111, states[0] = -94.901042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1475270877, states[0] = -94.985948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1483810461, states[0] = -95.020479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1490724260, states[0] = -94.922764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1501569249, states[0] = -3.525924, states[40]= 0.004104
Saving checkpoint... 
Iteration: 1512070693, states[0] = -5.668598, states[40]= 0.003706
Saving checkpoint... 
Iteration: 1524877857, states[0] = -95.346600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1537349424, states[0] = -95.015965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1550927914, states[0] = -95.314799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1563719163, states[0] = -64.977734, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1577778297, states[0] = -15.633918, states[40]= 0.001592
Saving checkpoint... 
Iteration: 1591359162, states[0] = -95.181333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1606159766, states[0] = -95.368027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1620152469, states[0] = -95.138112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1632841045, states[0] = -95.349308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1646567434, states[0] = -95.212380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1659776902, states[0] = -95.236997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1672949888, states[0] = -95.097493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1686535788, states[0] = -95.343852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1700701886, states[0] = 49.511539, states[40]= 0.053093
Saving checkpoint... 
Iteration: 1714051038, states[0] = -95.120558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1728223599, states[0] = -95.327207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1743108910, states[0] = -52.028182, states[40]= 0.000022
Saving checkpoint... 
Iteration: 1757135802, states[0] = 14.873151, states[40]= 0.006923
Saving checkpoint... 
Iteration: 1766590089, states[0] = -95.267508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1776340592, states[0] = 12.438687, states[40]= 0.006455
Saving checkpoint... 
Iteration: 1786989969, states[0] = -95.267249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1796617552, states[0] = -95.318005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1805892271, states[0] = -95.128083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1819838021, states[0] = -95.085289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1832877538, states[0] = -95.088671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1843781899, states[0] = -95.021438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1857817812, states[0] = -95.041736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1871477675, states[0] = -95.090376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1885235870, states[0] = -94.948729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1899993768, states[0] = -95.086345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1914530270, states[0] = 19.295281, states[40]= 0.006755
Saving checkpoint... 
Iteration: 1928077609, states[0] = -2.192138, states[40]= 0.004060
Saving checkpoint... 
Iteration: 1941832347, states[0] = -95.035689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1953855267, states[0] = -95.047020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1969568254, states[0] = 3.306404, states[40]= 0.004785
Saving checkpoint... 
Iteration: 1984918912, states[0] = -95.068309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1997816095, states[0] = -95.024372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2011679658, states[0] = -94.825269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2024884948, states[0] = -95.057924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2039771435, states[0] = -94.986297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2050148347, states[0] = -77.916539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2059187733, states[0] = -94.849992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2069617448, states[0] = -39.556461, states[40]= 0.000137
Saving checkpoint... 
Iteration: 2078864431, states[0] = -95.049944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2090417012, states[0] = -95.067351, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.957962
 - CaMKt in component CaMK (millimolar): 0.006680
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.632765
 - nass in component intracellular_ions (millimolar): 6.632825
 - ki in component intracellular_ions (millimolar): 145.348082
 - kss in component intracellular_ions (millimolar): 145.348060
 - cansr in component intracellular_ions (millimolar): 1.302718
 - cajsr in component intracellular_ions (millimolar): 1.265524
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003598
 - hf in component INa (dimensionless): 0.880971
 - hs in component INa (dimensionless): 0.880966
 - j in component INa (dimensionless): 0.880937
 - hsp in component INa (dimensionless): 0.727661
 - jp in component INa (dimensionless): 0.880918
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.712378
 - hLp in component INaL (dimensionless): 0.456602
 - a in component Ito (dimensionless): 0.000621
 - iF in component Ito (dimensionless): 0.999871
 - iS in component Ito (dimensionless): 0.625825
 - ap in component Ito (dimensionless): 0.000316
 - iFp in component Ito (dimensionless): 0.999871
 - iSp in component Ito (dimensionless): 0.700945
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934697
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999887
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001588
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.343105
 - xs1 in component IKs (dimensionless): 0.238207
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997322
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
22:59:50 (13492): called boinc_finish(0)

</stderr_txt>
]]>


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