𝕏

Task 54810820

Name HuVeMOp_20240626065019623306_ORdGradInc_k_24-Pueyo_APDR-conf_985_0
Workunit 26025195
Created 26 Jun 2024, 4:57:16 UTC
Sent 26 Jun 2024, 10:33:10 UTC
Report deadline 29 Jun 2024, 20:09:10 UTC
Received 28 Jun 2024, 13:55:14 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 237135
Run time 2 hours 59 min 26 sec
CPU time 1 hours 44 min 20 sec
Validate state Valid
Credit 64.25
Device peak FLOPS 4.35 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 8.31 MB
Peak swap size 4.45 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626065019623306_ORdGradInc_k_24-Pueyo_APDR-conf_985.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626065019623306_ORdGradInc_k_24-Pueyo_APDR-conf_985_0_r874898697_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626065019623306_ORdGradInc_k_24-Pueyo_APDR-conf_985_0_r874898697_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 94.714014
     * GNaL_b in INaL: 0.008742
     * Gto_b in Ito: 0.081126
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.033372
     * GKs_b in IKs: 0.001859
     * GK1_b in IK1: 0.156928
     * Gncx_b in INaCa_i: 0.000951
     * Pnak_b in INaK: 62.882422
     * GKb_b in IKb: 0.003773
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.052132
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 8015005, states[0] = 23.058312, states[40]= 0.018121
Saving checkpoint... 
Iteration: 15646623, states[0] = -63.615340, states[40]= 0.000003
Saving checkpoint... 
Iteration: 23333431, states[0] = -95.002828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33678146, states[0] = -94.688265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 43759212, states[0] = -94.928831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 53574793, states[0] = 3.036392, states[40]= 0.004551
Saving checkpoint... 
Iteration: 63636407, states[0] = -49.813324, states[40]= 0.000033
Saving checkpoint... 
Iteration: 73393523, states[0] = -95.008255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 83290572, states[0] = -94.951789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97548465, states[0] = 14.218995, states[40]= 0.004939
Saving checkpoint... 
Iteration: 113432391, states[0] = -95.014755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 127491681, states[0] = -95.023920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 144438559, states[0] = -95.015043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 161193158, states[0] = -94.807256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 176816342, states[0] = -94.967504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 193008227, states[0] = 24.864333, states[40]= 0.077662
Saving checkpoint... 
Iteration: 204117114, states[0] = -29.914614, states[40]= 0.000515
Saving checkpoint... 
Iteration: 222430269, states[0] = -95.012627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 238438322, states[0] = -95.014288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 254770936, states[0] = -94.929033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 269037355, states[0] = 18.145659, states[40]= 0.005241
Saving checkpoint... 
Iteration: 284144315, states[0] = -58.462585, states[40]= 0.000008
Saving checkpoint... 
Iteration: 299027218, states[0] = 21.136671, states[40]= 0.006288
Saving checkpoint... 
Iteration: 313590273, states[0] = -6.095742, states[40]= 0.003138
Saving checkpoint... 
Iteration: 320159463, states[0] = -79.709296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 335394751, states[0] = -95.003216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 352654480, states[0] = -71.709506, states[40]= 0.000001
Saving checkpoint... 
Iteration: 369982442, states[0] = -95.021462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 388932366, states[0] = -95.012894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 405576248, states[0] = 2.530725, states[40]= 0.004498
Saving checkpoint... 
Iteration: 423702296, states[0] = -94.826123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 442880554, states[0] = -94.998467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 453791187, states[0] = -94.948093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 465971482, states[0] = -95.019857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 480969760, states[0] = -95.019590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 488509187, states[0] = 24.447447, states[40]= 0.061662
Saving checkpoint... 
Iteration: 502869379, states[0] = -94.994271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 519468516, states[0] = -95.019375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 531761862, states[0] = -94.918803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 542423500, states[0] = -95.010800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 557237894, states[0] = -94.887421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 571422442, states[0] = -95.010532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 587562546, states[0] = 8.792285, states[40]= 0.004838
Saving checkpoint... 
Iteration: 603758060, states[0] = -94.914274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 620037606, states[0] = 18.063578, states[40]= 0.005228
Saving checkpoint... 
Iteration: 635242757, states[0] = -94.894355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 650114136, states[0] = -27.158099, states[40]= 0.000653
Saving checkpoint... 
Iteration: 660000275, states[0] = -61.177499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 666459162, states[0] = -95.017785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 676503369, states[0] = 34.670998, states[40]= 0.157428
Saving checkpoint... 
Iteration: 684546685, states[0] = 14.910451, states[40]= 0.004959
Saving checkpoint... 
Iteration: 700288652, states[0] = -94.945731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 714552092, states[0] = 12.910218, states[40]= 0.004908
Saving checkpoint... 
Iteration: 726516614, states[0] = 23.214856, states[40]= 0.013585
Saving checkpoint... 
Iteration: 739453712, states[0] = -95.016804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 748319768, states[0] = -94.969063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 754295096, states[0] = -94.951159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 760584205, states[0] = -1.947961, states[40]= 0.003932
Saving checkpoint... 
Iteration: 766303508, states[0] = -94.957763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 774089404, states[0] = -5.454116, states[40]= 0.003273
Saving checkpoint... 
Iteration: 783798266, states[0] = -94.953697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 794458960, states[0] = -95.017664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 804495895, states[0] = -95.022840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 813591807, states[0] = -7.266889, states[40]= 0.002888
Saving checkpoint... 
Iteration: 825667481, states[0] = -91.339063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 836623479, states[0] = -35.898569, states[40]= 0.000254
Saving checkpoint... 
Iteration: 848346907, states[0] = -94.984187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 859463801, states[0] = -95.018409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 873546715, states[0] = 14.899603, states[40]= 0.004959
Saving checkpoint... 
Iteration: 886659851, states[0] = -80.372654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 900613900, states[0] = -26.941008, states[40]= 0.000663
Saving checkpoint... 
Iteration: 914544168, states[0] = 15.813737, states[40]= 0.005003
Saving checkpoint... 
Iteration: 930073607, states[0] = 3.848835, states[40]= 0.004605
Saving checkpoint... 
Iteration: 942979836, states[0] = -95.020717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 953996586, states[0] = -95.022818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 966045463, states[0] = 15.351450, states[40]= 0.004979
Saving checkpoint... 
Iteration: 975446680, states[0] = -95.015367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 986950393, states[0] = -95.016043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1001649436, states[0] = -64.775318, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1015265220, states[0] = -94.922284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1027360455, states[0] = -94.990257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1040995873, states[0] = -95.022676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1053602762, states[0] = -16.742693, states[40]= 0.001250
Saving checkpoint... 
Iteration: 1067154459, states[0] = -71.677216, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1078802832, states[0] = -94.957038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1091672510, states[0] = -93.923033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1106136664, states[0] = -49.606244, states[40]= 0.000034
Saving checkpoint... 
Iteration: 1122622024, states[0] = -34.508804, states[40]= 0.000305
Saving checkpoint... 
Iteration: 1136107617, states[0] = -21.187052, states[40]= 0.000922
Saving checkpoint... 
Iteration: 1148681502, states[0] = -94.728661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1155568678, states[0] = 6.150326, states[40]= 0.004743
Saving checkpoint... 
Iteration: 1164110605, states[0] = -23.920433, states[40]= 0.000799
Saving checkpoint... 
Iteration: 1172048646, states[0] = 14.193866, states[40]= 0.004936
Saving checkpoint... 
Iteration: 1180824652, states[0] = -94.971812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1191013277, states[0] = 23.637284, states[40]= 0.024333
Saving checkpoint... 
Iteration: 1204725428, states[0] = -94.867507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1216216656, states[0] = -94.852451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1229186561, states[0] = -94.782608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1242528328, states[0] = 20.848637, states[40]= 0.006095
Saving checkpoint... 
Iteration: 1255516062, states[0] = 23.288459, states[40]= 0.014752
Saving checkpoint... 
Iteration: 1269153922, states[0] = -70.889153, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1281182734, states[0] = -94.748520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1294232547, states[0] = -94.878839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1306625414, states[0] = -37.773747, states[40]= 0.000197
Saving checkpoint... 
Iteration: 1319237629, states[0] = -94.886506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1332303285, states[0] = -94.957207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1343970442, states[0] = -95.019101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1356645038, states[0] = -59.325870, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1369352438, states[0] = -94.986457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1381070177, states[0] = 5.469687, states[40]= 0.004708
Saving checkpoint... 
Iteration: 1391697139, states[0] = -94.814979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1402320467, states[0] = -94.969060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1412946106, states[0] = -95.014960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1424068603, states[0] = 6.184041, states[40]= 0.004745
Saving checkpoint... 
Iteration: 1434864495, states[0] = -94.991671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1444406642, states[0] = -95.005909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1456058755, states[0] = 10.332314, states[40]= 0.004870
Saving checkpoint... 
Iteration: 1467034689, states[0] = 19.000721, states[40]= 0.005405
Saving checkpoint... 
Iteration: 1481431582, states[0] = -95.011976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493933291, states[0] = -95.012334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1506952074, states[0] = 9.297347, states[40]= 0.005508
Saving checkpoint... 
Iteration: 1521374431, states[0] = -5.019348, states[40]= 0.003795
Saving checkpoint... 
Iteration: 1531926780, states[0] = -63.194476, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1540863224, states[0] = 2.382292, states[40]= 0.005105
Saving checkpoint... 
Iteration: 1550645611, states[0] = -95.253306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1560706889, states[0] = -39.586275, states[40]= 0.000156
Saving checkpoint... 
Iteration: 1571783044, states[0] = -14.544024, states[40]= 0.001730
Saving checkpoint... 
Iteration: 1584734981, states[0] = -78.124278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1598616150, states[0] = -95.226084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1613172594, states[0] = -4.839506, states[40]= 0.003879
Saving checkpoint... 
Iteration: 1624492703, states[0] = -95.311011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1638166888, states[0] = -95.122139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1649836675, states[0] = -81.731884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1664300822, states[0] = -95.202381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1678357740, states[0] = -95.058493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1691189758, states[0] = -21.981631, states[40]= 0.000925
Saving checkpoint... 
Iteration: 1705568334, states[0] = -1.595295, states[40]= 0.004552
Saving checkpoint... 
Iteration: 1718514719, states[0] = -49.569903, states[40]= 0.000037
Saving checkpoint... 
Iteration: 1729459784, states[0] = -95.285254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1743365462, states[0] = 0.402514, states[40]= 0.004876
Saving checkpoint... 
Iteration: 1756721024, states[0] = -95.237343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1771503790, states[0] = 33.781426, states[40]= 0.141576
Saving checkpoint... 
Iteration: 1786243351, states[0] = 12.595984, states[40]= 0.005876
Saving checkpoint... 
Iteration: 1800224325, states[0] = -94.972386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1812411126, states[0] = -95.057736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1824643099, states[0] = -59.990573, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1836146013, states[0] = -62.732255, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1845803790, states[0] = -94.977892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1856184467, states[0] = -94.788504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1867539416, states[0] = 17.310023, states[40]= 0.005146
Saving checkpoint... 
Iteration: 1879455667, states[0] = -95.024152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1893935613, states[0] = -95.017667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1905240299, states[0] = -94.893721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1919829574, states[0] = -94.976635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1934009392, states[0] = 24.367738, states[40]= 0.058691
Saving checkpoint... 
Iteration: 1946975986, states[0] = -95.020564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1960779289, states[0] = -94.936952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1973002079, states[0] = 42.943006, states[40]= 0.107933
Saving checkpoint... 
Iteration: 1988006355, states[0] = 26.424728, states[40]= 0.118624
Saving checkpoint... 
Iteration: 1998806597, states[0] = -94.959394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2012523474, states[0] = 22.016225, states[40]= 0.007284
Saving checkpoint... 
Iteration: 2026198408, states[0] = -94.817237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2039525408, states[0] = 21.580545, states[40]= 0.006687
Saving checkpoint... 
Iteration: 2054368156, states[0] = -94.992704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2067957502, states[0] = -95.016509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2081978954, states[0] = -95.019766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2092960957, states[0] = -95.017048, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.898238
 - CaMKt in component CaMK (millimolar): 0.007253
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.811336
 - nass in component intracellular_ions (millimolar): 6.811396
 - ki in component intracellular_ions (millimolar): 145.163209
 - kss in component intracellular_ions (millimolar): 145.163188
 - cansr in component intracellular_ions (millimolar): 1.323672
 - cajsr in component intracellular_ions (millimolar): 1.284846
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003620
 - hf in component INa (dimensionless): 0.879938
 - hs in component INa (dimensionless): 0.879934
 - j in component INa (dimensionless): 0.879905
 - hsp in component INa (dimensionless): 0.725713
 - jp in component INa (dimensionless): 0.879887
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.708563
 - hLp in component INaL (dimensionless): 0.448161
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.615022
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.688280
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.927610
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999862
 - jca in component ICaL (dimensionless): 0.999974
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001643
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.339790
 - xs1 in component IKs (dimensionless): 0.255603
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997338
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
22:54:59 (34924): called boinc_finish(0)

</stderr_txt>
]]>


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