𝕏

Task 54803078

Name HuVeMOp_20240626065019623306_ORdGradInc_k_24-TESZT_Block_K1_75-conf_759_0
Workunit 26021342
Created 26 Jun 2024, 4:53:47 UTC
Sent 26 Jun 2024, 9:20:35 UTC
Report deadline 29 Jun 2024, 9:20:35 UTC
Received 28 Jun 2024, 14:42:54 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 232654
Run time 33 min 4 sec
CPU time 30 min 37 sec
Validate state Valid
Credit 35.92
Device peak FLOPS 4.99 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 2.78 MB
Peak swap size 391.76 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626065019623306_ORdGradInc_k_24-TESZT_Block_K1_75-conf_759.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626065019623306_ORdGradInc_k_24-TESZT_Block_K1_75-conf_759_0_r1575950680_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626065019623306_ORdGradInc_k_24-TESZT_Block_K1_75-conf_759_0_r1575950680_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 99.923445
     * GNaL_b in INaL: 0.006383
     * Gto_b in Ito: 0.068648
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.031935
     * GKs_b in IKs: 0.001778
     * GK1_b in IK1: 0.041883
     * Gncx_b in INaCa_i: 0.000949
     * Pnak_b in INaK: 66.294535
     * GKb_b in IKb: 0.003929
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036071
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 48744301, states[0] = -89.497719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97964690, states[0] = -91.562402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 146891252, states[0] = -91.419274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 196316329, states[0] = -91.077093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 244425806, states[0] = -91.486320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 293292687, states[0] = -90.847960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 342183058, states[0] = -75.481532, states[40]= 0.000001


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626065019623306_ORdGradInc_k_24-TESZT_Block_K1_75-conf_759.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626065019623306_ORdGradInc_k_24-TESZT_Block_K1_75-conf_759_0_r1575950680_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626065019623306_ORdGradInc_k_24-TESZT_Block_K1_75-conf_759_0_r1575950680_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 99.923445
     * GNaL_b in INaL: 0.006383
     * Gto_b in Ito: 0.068648
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.031935
     * GKs_b in IKs: 0.001778
     * GK1_b in IK1: 0.041883
     * Gncx_b in INaCa_i: 0.000949
     * Pnak_b in INaK: 66.294535
     * GKb_b in IKb: 0.003929
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036071
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 342183058
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -75.481532 (After loading)
 - states[40]: 0.000001 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 388911703, states[0] = -91.458967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 434760319, states[0] = -90.135059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 481218852, states[0] = -86.060062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 527529291, states[0] = 25.720364, states[40]= 0.001585
Saving checkpoint... 
Iteration: 575022799, states[0] = 27.681047, states[40]= 0.001858
Saving checkpoint... 
Iteration: 622481501, states[0] = -91.549517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 669581858, states[0] = 2.604865, states[40]= 0.004619
Saving checkpoint... 
Iteration: 717588286, states[0] = -1.706276, states[40]= 0.004298
Saving checkpoint... 
Iteration: 764964305, states[0] = -91.534014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 812401792, states[0] = -91.435501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 859332525, states[0] = -91.177714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 906438802, states[0] = -91.502948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 953701728, states[0] = -81.908127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1000590773, states[0] = -3.600949, states[40]= 0.004006
Saving checkpoint... 
Iteration: 1047796836, states[0] = -90.893266, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626065019623306_ORdGradInc_k_24-TESZT_Block_K1_75-conf_759.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626065019623306_ORdGradInc_k_24-TESZT_Block_K1_75-conf_759_0_r1575950680_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626065019623306_ORdGradInc_k_24-TESZT_Block_K1_75-conf_759_0_r1575950680_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 99.923445
     * GNaL_b in INaL: 0.006383
     * Gto_b in Ito: 0.068648
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.031935
     * GKs_b in IKs: 0.001778
     * GK1_b in IK1: 0.041883
     * Gncx_b in INaCa_i: 0.000949
     * Pnak_b in INaK: 66.294535
     * GKb_b in IKb: 0.003929
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036071
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1047796836
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -90.893266 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1092699862, states[0] = -81.351842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1137829869, states[0] = -91.160880, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626065019623306_ORdGradInc_k_24-TESZT_Block_K1_75-conf_759.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626065019623306_ORdGradInc_k_24-TESZT_Block_K1_75-conf_759_0_r1575950680_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626065019623306_ORdGradInc_k_24-TESZT_Block_K1_75-conf_759_0_r1575950680_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 99.923445
     * GNaL_b in INaL: 0.006383
     * Gto_b in Ito: 0.068648
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.031935
     * GKs_b in IKs: 0.001778
     * GK1_b in IK1: 0.041883
     * Gncx_b in INaCa_i: 0.000949
     * Pnak_b in INaK: 66.294535
     * GKb_b in IKb: 0.003929
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036071
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1137829869
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -91.160880 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1182441310, states[0] = -91.505176, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626065019623306_ORdGradInc_k_24-TESZT_Block_K1_75-conf_759.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626065019623306_ORdGradInc_k_24-TESZT_Block_K1_75-conf_759_0_r1575950680_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626065019623306_ORdGradInc_k_24-TESZT_Block_K1_75-conf_759_0_r1575950680_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 99.923445
     * GNaL_b in INaL: 0.006383
     * Gto_b in Ito: 0.068648
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.031935
     * GKs_b in IKs: 0.001778
     * GK1_b in IK1: 0.041883
     * Gncx_b in INaCa_i: 0.000949
     * Pnak_b in INaK: 66.294535
     * GKb_b in IKb: 0.003929
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036071
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1182441310
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -91.505176 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1228121875, states[0] = -32.974555, states[40]= 0.000759
Saving checkpoint... 
Iteration: 1273777051, states[0] = -90.594979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1321192543, states[0] = -78.985727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1368302356, states[0] = -90.949860, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626065019623306_ORdGradInc_k_24-TESZT_Block_K1_75-conf_759.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626065019623306_ORdGradInc_k_24-TESZT_Block_K1_75-conf_759_0_r1575950680_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626065019623306_ORdGradInc_k_24-TESZT_Block_K1_75-conf_759_0_r1575950680_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 99.923445
     * GNaL_b in INaL: 0.006383
     * Gto_b in Ito: 0.068648
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.031935
     * GKs_b in IKs: 0.001778
     * GK1_b in IK1: 0.041883
     * Gncx_b in INaCa_i: 0.000949
     * Pnak_b in INaK: 66.294535
     * GKb_b in IKb: 0.003929
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036071
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1368302356
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -90.949860 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1412686192, states[0] = -76.692715, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1457606387, states[0] = -18.202265, states[40]= 0.001374


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626065019623306_ORdGradInc_k_24-TESZT_Block_K1_75-conf_759.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626065019623306_ORdGradInc_k_24-TESZT_Block_K1_75-conf_759_0_r1575950680_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626065019623306_ORdGradInc_k_24-TESZT_Block_K1_75-conf_759_0_r1575950680_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 99.923445
     * GNaL_b in INaL: 0.006383
     * Gto_b in Ito: 0.068648
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.031935
     * GKs_b in IKs: 0.001778
     * GK1_b in IK1: 0.041883
     * Gncx_b in INaCa_i: 0.000949
     * Pnak_b in INaK: 66.294535
     * GKb_b in IKb: 0.003929
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036071
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1457606387
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -18.202265 (After loading)
 - states[40]: 0.001374 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -91.433202
 - CaMKt in component CaMK (millimolar): 0.012397
 - cass in component intracellular_ions (millimolar): 0.000087
 - nai in component intracellular_ions (millimolar): 6.687044
 - nass in component intracellular_ions (millimolar): 6.687137
 - ki in component intracellular_ions (millimolar): 145.199255
 - kss in component intracellular_ions (millimolar): 145.199235
 - cansr in component intracellular_ions (millimolar): 1.644713
 - cajsr in component intracellular_ions (millimolar): 1.602562
 - cai in component intracellular_ions (millimolar): 0.000089
 - m in component INa (dimensionless): 0.005134
 - hf in component INa (dimensionless): 0.805730
 - hs in component INa (dimensionless): 0.805695
 - j in component INa (dimensionless): 0.805454
 - hsp in component INa (dimensionless): 0.599417
 - jp in component INa (dimensionless): 0.805264
 - mL in component INaL (dimensionless): 0.000096
 - hL in component INaL (dimensionless): 0.594836
 - hLp in component INaL (dimensionless): 0.318026
 - a in component Ito (dimensionless): 0.000788
 - iF in component Ito (dimensionless): 0.999761
 - iS in component Ito (dimensionless): 0.576607
 - ap in component Ito (dimensionless): 0.000401
 - iFp in component Ito (dimensionless): 0.999761
 - iSp in component Ito (dimensionless): 0.632424
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.914384
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999825
 - jca in component ICaL (dimensionless): 0.999972
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002977
 - xrf in component IKr (dimensionless): 0.000005
 - xrs in component IKr (dimensionless): 0.442320
 - xs1 in component IKs (dimensionless): 0.270623
 - xs2 in component IKs (dimensionless): 0.000130
 - xk1 in component IK1 (dimensionless): 0.998111
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
15:42:29 (43349): called boinc_finish(0)

</stderr_txt>
]]>