𝕏

Task 54799178

Name HuVeMOp_20240626065019623306_ORdGradInc_k_24-Pueyo_APDR-conf_29_0
Workunit 26019396
Created 26 Jun 2024, 4:52:03 UTC
Sent 26 Jun 2024, 8:45:13 UTC
Report deadline 29 Jun 2024, 18:21:13 UTC
Received 26 Jun 2024, 12:58:30 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 213441
Run time 2 hours 51 min 22 sec
CPU time 2 hours 18 min 16 sec
Validate state Valid
Credit 62.43
Device peak FLOPS 3.72 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.43 MB
Peak swap size 6.23 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.16.11</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626065019623306_ORdGradInc_k_24-Pueyo_APDR-conf_29.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626065019623306_ORdGradInc_k_24-Pueyo_APDR-conf_29_0_r849445953_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626065019623306_ORdGradInc_k_24-Pueyo_APDR-conf_29_0_r849445953_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 105.593776
     * GNaL_b in INaL: 0.006658
     * Gto_b in Ito: 0.068543
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.033118
     * GKs_b in IKs: 0.001752
     * GK1_b in IK1: 0.166803
     * Gncx_b in INaCa_i: 0.000948
     * Pnak_b in INaK: 66.800503
     * GKb_b in IKb: 0.003776
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.042794
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 15096667, states[0] = -21.149235, states[40]= 0.000895
Saving checkpoint... 
Iteration: 29314160, states[0] = -95.030886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 43831599, states[0] = -95.027809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58849758, states[0] = -95.028434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 74161805, states[0] = -94.088470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 90338623, states[0] = -95.015130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 105829227, states[0] = -95.008452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 121338073, states[0] = -95.011606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 137043726, states[0] = 14.381771, states[40]= 0.005480
Saving checkpoint... 
Iteration: 152238385, states[0] = -94.928281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167787476, states[0] = -94.978466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 182230227, states[0] = -94.916596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 197322124, states[0] = -95.001295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 212436245, states[0] = -95.040020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226433621, states[0] = -95.039455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 241446099, states[0] = -95.041691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 257000578, states[0] = 29.022227, states[40]= 0.001294
Saving checkpoint... 
Iteration: 272367695, states[0] = -95.021654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 287479428, states[0] = -95.046542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 302613435, states[0] = -34.688836, states[40]= 0.000272
Saving checkpoint... 
Iteration: 317176518, states[0] = -94.813634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 331358387, states[0] = -95.018088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 345778931, states[0] = -94.970699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 359337425, states[0] = -95.008915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 375620979, states[0] = -42.473429, states[40]= 0.000091
Saving checkpoint... 
Iteration: 391184110, states[0] = -94.835630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 404984599, states[0] = -95.047093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 415053048, states[0] = 10.521624, states[40]= 0.005215
Saving checkpoint... 
Iteration: 423455084, states[0] = -95.043004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432945442, states[0] = -95.041399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 443148864, states[0] = -78.318281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 452300007, states[0] = -94.987039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 462130288, states[0] = -52.897396, states[40]= 0.000018
Saving checkpoint... 
Iteration: 471889860, states[0] = -95.028721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 481720031, states[0] = -94.900820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 490997763, states[0] = -95.048523, states[40]= 0.000000
Saving checkpoint... 
Iteration: 500049789, states[0] = 11.905126, states[40]= 0.005289
Saving checkpoint... 
Iteration: 509048521, states[0] = 12.435576, states[40]= 0.005322
Saving checkpoint... 
Iteration: 521354810, states[0] = -95.016542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 533412747, states[0] = -95.034705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 544139296, states[0] = -63.851610, states[40]= 0.000003
Saving checkpoint... 
Iteration: 555280773, states[0] = -94.972156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 566677129, states[0] = -94.816083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 578560850, states[0] = 7.056846, states[40]= 0.005043
Saving checkpoint... 
Iteration: 590910502, states[0] = -95.034139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 602693200, states[0] = -94.853784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 613574480, states[0] = 0.019785, states[40]= 0.004401
Saving checkpoint... 
Iteration: 625744922, states[0] = -94.935356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 639508979, states[0] = 26.174026, states[40]= 0.065773
Saving checkpoint... 
Iteration: 652783503, states[0] = -94.974386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 665979372, states[0] = -95.046306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 679190908, states[0] = -94.849303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 691238851, states[0] = -94.927647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 703808398, states[0] = -94.992519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 715892637, states[0] = -95.029387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 726251784, states[0] = -94.943420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 737550830, states[0] = 11.466528, states[40]= 0.005264
Saving checkpoint... 
Iteration: 751851348, states[0] = -95.014978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 766696227, states[0] = -94.859453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 781872129, states[0] = -95.022907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 796564097, states[0] = 5.526104, states[40]= 0.004951
Saving checkpoint... 
Iteration: 810893183, states[0] = -95.029489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 825491125, states[0] = -95.047615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 839963568, states[0] = -95.044063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 854209122, states[0] = -94.882687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 868681425, states[0] = -94.829162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 882530323, states[0] = 19.486847, states[40]= 0.006614
Saving checkpoint... 
Iteration: 896537611, states[0] = 16.821288, states[40]= 0.005819
Saving checkpoint... 
Iteration: 911107469, states[0] = -28.762230, states[40]= 0.000528
Saving checkpoint... 
Iteration: 924844119, states[0] = -95.011725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 940175318, states[0] = -94.807211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 955700399, states[0] = -94.867110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 971141532, states[0] = -66.838686, states[40]= 0.000002
Saving checkpoint... 
Iteration: 986398693, states[0] = -95.030912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1001747876, states[0] = -94.938712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1016792836, states[0] = -94.981531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1032034688, states[0] = 17.923650, states[40]= 0.006068
Saving checkpoint... 
Iteration: 1047392478, states[0] = -95.029157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1062709166, states[0] = -94.882646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1078201168, states[0] = -94.868449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1093694930, states[0] = -94.856814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1109398974, states[0] = -95.030919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1124779331, states[0] = -94.970606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1140474102, states[0] = -95.045362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1155807194, states[0] = -94.991489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1171235088, states[0] = -94.922382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1186673768, states[0] = -94.796522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1202075083, states[0] = -0.341331, states[40]= 0.004350
Saving checkpoint... 
Iteration: 1217569235, states[0] = 2.944852, states[40]= 0.004744
Saving checkpoint... 
Iteration: 1232918328, states[0] = -95.035598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1248551533, states[0] = 11.168712, states[40]= 0.005248
Saving checkpoint... 
Iteration: 1264178381, states[0] = -94.820282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1279451130, states[0] = -95.041889, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626065019623306_ORdGradInc_k_24-Pueyo_APDR-conf_29.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626065019623306_ORdGradInc_k_24-Pueyo_APDR-conf_29_0_r849445953_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626065019623306_ORdGradInc_k_24-Pueyo_APDR-conf_29_0_r849445953_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 105.593776
     * GNaL_b in INaL: 0.006658
     * Gto_b in Ito: 0.068543
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.033118
     * GKs_b in IKs: 0.001752
     * GK1_b in IK1: 0.166803
     * Gncx_b in INaCa_i: 0.000948
     * Pnak_b in INaK: 66.800503
     * GKb_b in IKb: 0.003776
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.042794
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1279451130
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -95.041889 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1293442777, states[0] = -95.040453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1307140083, states[0] = -64.883138, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1320536495, states[0] = 17.246847, states[40]= 0.005906
Saving checkpoint... 
Iteration: 1334035919, states[0] = 17.464285, states[40]= 0.005954
Saving checkpoint... 
Iteration: 1348062013, states[0] = 6.516098, states[40]= 0.005013
Saving checkpoint... 
Iteration: 1360933982, states[0] = -95.038784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1374283227, states[0] = -94.973755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1388247718, states[0] = -94.938308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1401842945, states[0] = -95.010925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415303174, states[0] = -94.988679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1429008879, states[0] = 26.238101, states[40]= 0.067240
Saving checkpoint... 
Iteration: 1442226040, states[0] = -94.909425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1455288045, states[0] = -94.977601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1468669721, states[0] = -94.736863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1481664524, states[0] = -94.420386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1495109944, states[0] = -31.207909, states[40]= 0.000413
Saving checkpoint... 
Iteration: 1508381576, states[0] = -95.261922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1521847011, states[0] = -95.246085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1535572562, states[0] = -95.139950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1549029167, states[0] = -79.225105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1562463201, states[0] = -0.539351, states[40]= 0.004840
Saving checkpoint... 
Iteration: 1575902303, states[0] = 44.914554, states[40]= 0.078695
Saving checkpoint... 
Iteration: 1589141088, states[0] = 12.526483, states[40]= 0.006375
Saving checkpoint... 
Iteration: 1602599300, states[0] = -95.317736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1616228405, states[0] = -79.360645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1629572643, states[0] = -95.301431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1643352434, states[0] = -95.284441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1656336583, states[0] = 14.759519, states[40]= 0.006762
Saving checkpoint... 
Iteration: 1670214902, states[0] = -58.279861, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1684128251, states[0] = -95.258382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1697563634, states[0] = -95.141067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1710996259, states[0] = -35.292958, states[40]= 0.000254
Saving checkpoint... 
Iteration: 1725083970, states[0] = -21.485731, states[40]= 0.000948
Saving checkpoint... 
Iteration: 1738954704, states[0] = -95.111805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1752817578, states[0] = -95.244313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1766483284, states[0] = -20.716872, states[40]= 0.001008
Saving checkpoint... 
Iteration: 1779751766, states[0] = -95.092052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1793105547, states[0] = 31.292975, states[40]= 0.114094
Saving checkpoint... 
Iteration: 1807629991, states[0] = -57.027310, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1820715836, states[0] = -94.927894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1833763677, states[0] = -94.980198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1847605049, states[0] = -27.453680, states[40]= 0.000590
Saving checkpoint... 
Iteration: 1861218405, states[0] = -94.908772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1874526030, states[0] = 20.814550, states[40]= 0.007508
Saving checkpoint... 
Iteration: 1888523595, states[0] = 21.592072, states[40]= 0.008357
Saving checkpoint... 
Iteration: 1901600440, states[0] = -22.078874, states[40]= 0.000856
Saving checkpoint... 
Iteration: 1915224645, states[0] = -94.909424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1928633336, states[0] = -56.623342, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1942191712, states[0] = -94.851201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1955463607, states[0] = -95.044137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1969184688, states[0] = -94.836445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1982660824, states[0] = -93.595029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1995807189, states[0] = -94.991202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2009490682, states[0] = -95.047014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2022490345, states[0] = -95.046920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2035828628, states[0] = -95.003572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2049639452, states[0] = -64.058079, states[40]= 0.000003
Saving checkpoint... 
Iteration: 2063122682, states[0] = -44.312711, states[40]= 0.000069
Saving checkpoint... 
Iteration: 2076756138, states[0] = -94.947503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2090342332, states[0] = -95.010227, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.923700
 - CaMKt in component CaMK (millimolar): 0.006794
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.673767
 - nass in component intracellular_ions (millimolar): 6.673826
 - ki in component intracellular_ions (millimolar): 145.305560
 - kss in component intracellular_ions (millimolar): 145.305540
 - cansr in component intracellular_ions (millimolar): 1.307839
 - cajsr in component intracellular_ions (millimolar): 1.270459
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003611
 - hf in component INa (dimensionless): 0.880379
 - hs in component INa (dimensionless): 0.880375
 - j in component INa (dimensionless): 0.880350
 - hsp in component INa (dimensionless): 0.726547
 - jp in component INa (dimensionless): 0.880332
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.711605
 - hLp in component INaL (dimensionless): 0.456020
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.625152
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.700222
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934098
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999885
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001602
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.339263
 - xs1 in component IKs (dimensionless): 0.239155
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997331
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
07:57:58 (10700): called boinc_finish(0)

</stderr_txt>
]]>


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