𝕏

Task 54794140

Name HuVeMOp_20240626064103635658_ORdGradInc_k_24-Pueyo_APDR-conf_893_1
Workunit 26016877
Created 26 Jun 2024, 4:49:48 UTC
Sent 26 Jun 2024, 8:07:35 UTC
Report deadline 29 Jun 2024, 17:43:35 UTC
Received 26 Jun 2024, 10:54:37 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 232674
Run time 2 hours 29 min 50 sec
CPU time 2 hours 27 min 5 sec
Validate state Initial
Credit 0.00
Device peak FLOPS 5.37 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.79 MB
Peak swap size 32.60 GB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.24.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626064103635658_ORdGradInc_k_24-Pueyo_APDR-conf_893.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626064103635658_ORdGradInc_k_24-Pueyo_APDR-conf_893_1_r1328709885_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626064103635658_ORdGradInc_k_24-Pueyo_APDR-conf_893_1_r1328709885_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 121.885328
     * GNaL_b in INaL: 0.005985
     * Gto_b in Ito: 0.079393
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033104
     * GKs_b in IKs: 0.001832
     * GK1_b in IK1: 0.145681
     * Gncx_b in INaCa_i: 0.000958
     * Pnak_b in INaK: 64.919679
     * GKb_b in IKb: 0.003979
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.050461
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 16763337, states[0] = -94.877863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33202995, states[0] = -94.761079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 50086123, states[0] = -11.643478, states[40]= 0.002065
Saving checkpoint... 
Iteration: 65332054, states[0] = -94.889986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 81304101, states[0] = -94.867588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 98930565, states[0] = -94.918432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 116425338, states[0] = -94.915524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 131564464, states[0] = 3.791202, states[40]= 0.004753
Saving checkpoint... 
Iteration: 149646745, states[0] = -76.543902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 165832204, states[0] = -94.879051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 182165480, states[0] = -94.223569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 199878742, states[0] = -94.899623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 215540268, states[0] = 14.338609, states[40]= 0.005518
Saving checkpoint... 
Iteration: 233399016, states[0] = -94.906035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 250199931, states[0] = -94.723127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 265613357, states[0] = -37.678849, states[40]= 0.000170
Saving checkpoint... 
Iteration: 281851919, states[0] = -94.888419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 299357468, states[0] = -94.890900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 316258487, states[0] = -94.816934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 331947515, states[0] = -94.917318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 350138004, states[0] = -64.758050, states[40]= 0.000002
Saving checkpoint... 
Iteration: 365313577, states[0] = -94.866800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 383283337, states[0] = -94.842891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 399371443, states[0] = -94.896563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 416382500, states[0] = -94.900573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432765288, states[0] = -94.824651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 450755762, states[0] = -94.813570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 465914159, states[0] = -94.909959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 481769291, states[0] = -94.828959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 498690067, states[0] = -94.701934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 516080429, states[0] = -6.003317, states[40]= 0.003253
Saving checkpoint... 
Iteration: 531459351, states[0] = -94.919273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 548748565, states[0] = -94.804400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 565010512, states[0] = 23.560602, states[40]= 0.048920
Saving checkpoint... 
Iteration: 581683875, states[0] = -94.686573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599527249, states[0] = 18.998955, states[40]= 0.007087
Saving checkpoint... 
Iteration: 615104024, states[0] = -28.359961, states[40]= 0.000519
Saving checkpoint... 
Iteration: 633445069, states[0] = -94.916684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 649082828, states[0] = -7.955846, states[40]= 0.002826
Saving checkpoint... 
Iteration: 664688965, states[0] = -94.699333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 680467993, states[0] = -94.920560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 697577376, states[0] = -3.732844, states[40]= 0.003722
Saving checkpoint... 
Iteration: 714357251, states[0] = -94.890558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 729725521, states[0] = -94.770207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 746903254, states[0] = -94.906874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 764432063, states[0] = -94.913984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 780388529, states[0] = -94.902387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 796224968, states[0] = -94.769253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 814232403, states[0] = -94.781170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 830695128, states[0] = -94.712753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 847731458, states[0] = -94.779683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 865298854, states[0] = -94.855794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 880725967, states[0] = -94.770858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 897505320, states[0] = 29.112362, states[40]= 0.135408
Saving checkpoint... 
Iteration: 913986606, states[0] = -94.923017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 930390988, states[0] = -94.903094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 946248917, states[0] = -94.804637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 964470613, states[0] = -94.920794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 979881429, states[0] = -94.899886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 994896249, states[0] = -94.904688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1011582471, states[0] = -7.655829, states[40]= 0.002892
Saving checkpoint... 
Iteration: 1028580401, states[0] = -5.981198, states[40]= 0.003258
Saving checkpoint... 
Iteration: 1046495865, states[0] = -94.924064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1061951081, states[0] = -94.917553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1078923985, states[0] = -94.912005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1096649715, states[0] = -81.046492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1112026628, states[0] = 19.192697, states[40]= 0.007241
Saving checkpoint... 
Iteration: 1128567598, states[0] = 2.213318, states[40]= 0.004608
Saving checkpoint... 
Iteration: 1144037565, states[0] = 15.384959, states[40]= 0.005695
Saving checkpoint... 
Iteration: 1161541407, states[0] = 13.892168, states[40]= 0.005456
Saving checkpoint... 
Iteration: 1178015738, states[0] = 22.082937, states[40]= 0.017769
Saving checkpoint... 
Iteration: 1193527588, states[0] = 18.892027, states[40]= 0.007008
Saving checkpoint... 
Iteration: 1211812662, states[0] = -94.865701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1227481720, states[0] = -94.922207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1242951154, states[0] = -94.917464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1258101851, states[0] = -26.211295, states[40]= 0.000622
Saving checkpoint... 
Iteration: 1273827337, states[0] = -94.874975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1290005512, states[0] = 28.648526, states[40]= 0.132614
Saving checkpoint... 
Iteration: 1306683202, states[0] = -94.684196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1321500987, states[0] = 50.836323, states[40]= 0.022270
Saving checkpoint... 
Iteration: 1337631265, states[0] = -56.976278, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1353496403, states[0] = -94.923954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1369815927, states[0] = -94.867803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1385229045, states[0] = -94.775567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1401670634, states[0] = -94.557749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1416961089, states[0] = -94.919062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1433319752, states[0] = -94.870244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1448571094, states[0] = 0.274981, states[40]= 0.004381
Saving checkpoint... 
Iteration: 1464638445, states[0] = -65.289281, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1479966361, states[0] = -94.919862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497344727, states[0] = -94.884265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1512492847, states[0] = -95.065709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1530248678, states[0] = -95.172129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1545819119, states[0] = -95.146486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1562369254, states[0] = -95.214365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1579534909, states[0] = 14.278251, states[40]= 0.006797
Saving checkpoint... 
Iteration: 1594720187, states[0] = -95.165247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1610903156, states[0] = -95.138705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1627426528, states[0] = -95.177542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1644652659, states[0] = 4.510706, states[40]= 0.005465
Saving checkpoint... 
Iteration: 1659949315, states[0] = 6.503790, states[40]= 0.005676
Saving checkpoint... 
Iteration: 1676271896, states[0] = -95.073446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1694310353, states[0] = -95.153935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1709285582, states[0] = -95.105966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1726152763, states[0] = -95.211187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1742287478, states[0] = -95.110160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1757803023, states[0] = -46.754231, states[40]= 0.000046
Saving checkpoint... 
Iteration: 1775216167, states[0] = -63.288920, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1792136380, states[0] = -95.192251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1807051783, states[0] = 8.562053, states[40]= 0.005148
Saving checkpoint... 
Iteration: 1824721095, states[0] = -94.803990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1840735493, states[0] = -94.812276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1856173867, states[0] = -94.653247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1873274973, states[0] = -94.844520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1890275471, states[0] = -94.840939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1905079287, states[0] = -5.269129, states[40]= 0.003413
Saving checkpoint... 
Iteration: 1922509712, states[0] = 23.905646, states[40]= 0.058458
Saving checkpoint... 
Iteration: 1938811305, states[0] = -94.865919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1954182233, states[0] = -94.681859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1970796933, states[0] = -94.854251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1986961109, states[0] = -94.919103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2004210886, states[0] = -94.743803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2020623976, states[0] = -48.899316, states[40]= 0.000031
Saving checkpoint... 
Iteration: 2035913590, states[0] = -94.908986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2051011572, states[0] = 23.176179, states[40]= 0.038822
Saving checkpoint... 
Iteration: 2067948446, states[0] = -94.916504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2083959359, states[0] = -94.918382, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.799787
 - CaMKt in component CaMK (millimolar): 0.006689
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.737897
 - nass in component intracellular_ions (millimolar): 6.737955
 - ki in component intracellular_ions (millimolar): 145.242984
 - kss in component intracellular_ions (millimolar): 145.242964
 - cansr in component intracellular_ions (millimolar): 1.300483
 - cajsr in component intracellular_ions (millimolar): 1.263491
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003656
 - hf in component INa (dimensionless): 0.878219
 - hs in component INa (dimensionless): 0.878214
 - j in component INa (dimensionless): 0.878186
 - hsp in component INa (dimensionless): 0.722481
 - jp in component INa (dimensionless): 0.878167
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.708446
 - hLp in component INaL (dimensionless): 0.452584
 - a in component Ito (dimensionless): 0.000628
 - iF in component Ito (dimensionless): 0.999867
 - iS in component Ito (dimensionless): 0.626702
 - ap in component Ito (dimensionless): 0.000320
 - iFp in component Ito (dimensionless): 0.999867
 - iSp in component Ito (dimensionless): 0.702414
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.939237
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999899
 - jca in component ICaL (dimensionless): 0.999981
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001565
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.335675
 - xs1 in component IKs (dimensionless): 0.230953
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997364
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
12:48:37 (29416): called boinc_finish(0)

</stderr_txt>
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